Gene 86997.m00251 (T.vaginalis)

86997.m00251

Species: T.vaginalis
Alias: 86997.m00251, TvagK0961
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
86997.m00251.AA Protein None 304 None Fasta, JSON
86997.m00251.kin_dom Protein Kinase Domain None 154 None Fasta, JSON

Protein domain

Protein domains of 86997.m00251.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 86997.m00251.AA Ciliate-E2 59-253 18 3.3e-18 59.08 In-house 82-359 (365) Show / Hide 
Range on Protein: 59-253
Range on HMM: 82-359/365
Sequence Identity: 18% (55 aa)

ENKILSRISHKNIIKVFEKFQEKQ----------FNFTILEHFM---------------PVSLEKIGVIPKEQIR-------MYSLQILCALEHCSSYG-
| .||....|.|||| .| ||||.          ..   |....               . ....|. | |....       .|  .|..|||.. | . 
EKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN

IYIGNLSPKTIFIDKYGMIKFVDFQHAMLIPKRYC---------------------------------TRFSITTQFPAPEIVQGIPF--------NPKA
|   .. |  |..     || .||  .  . . ..                                  ..  |  . ||||..| .           ..
IIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYK

ADMWSIGIILFYMVNGTYPCKEFTNAEEYMASVENIKSIFQFNEDMLH------------------ADILIN----LFQTDPNIRAT-LEDV
.|.||.|.||..|. | .|          .   .. |  |...|  ..                   |.. .    ..| ||. | |  |..
CDIWSLGVILYEMLFGKPPF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQI
Kinase 86997.m00251.AA Ciliate-E2-Unclassified 35-253 15 2.8e-17 56.5 In-house 17-346 (352) Show / Hide 
Range on Protein: 35-253
Range on HMM: 17-346/352
Sequence Identity: 15% (50 aa)

EVQHRQHNQFF-------------VCKITESPKIFEIENKILSRIS-----------------HKNIIKVFEKFQEKQFNFTILEHFMPVS------LEK
..||.... ..             ...| ..  ..  | |.. ...                 |.....| . ..... .  ..             ..|
KCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKK

IGV-----------------IPKEQIR-----MYSLQILCALEHCSSYG-IYIGNLSPKTIFIDKYG---MIKFVDFQHAM-----------------LI
 .                  .. .|..      |  |||..||.. . . |   .. |  |..|. |    ||  ||. ..                  .
RKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIW

PKRYCTRFSITTQFP----APEIVQGIPFNP---KAADMWSIGIILFYMVNGTYPCKEFTNAE---------------EYMASV-ENIKSIFQFNE----
..  .. |. | ..     |||. ||   .    ...|.|| |.||..|. |.|| .  .  .               ..     ... ... |..    
KQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIP

DMLH--ADILIN-----LFQTDPNIRATLEDV
. ..  |  .||     ... .|| | |.|..
KHWSPEAKDFINDLLQKMLKKNPNKRITFEQI
Kinase 86997.m00251.AA CAMKL 171-255 24 2.2e-16 48.64 In-house 201-293 (297) Show / Hide 
Range on Protein: 171-255
Range on HMM: 201-293/297
Sequence Identity: 24% (23 aa)

APEIVQG--IPFNPKAADMWSIGIILFYMVNGTYPCKEFTN---AEEYMASVENIKSIFQFNED----M-LHADILINLFQTDPNIRATLEDVRK
||||.||   |.. ...|.||.|.||. || |..| .. |.     .     .... .  ....    .    |..  . |..|. |.|......
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMN
Kinase 86997.m00251.AA TSSK 171-203 57 4.6e-14 42.54 In-house 196-228 (289) Show / Hide 
Range on Protein: 171-203
Range on HMM: 196-228/289
Sequence Identity: 57% (19 aa)

APEIVQGIPFNPKAADMWSIGIILFYMVNGTYP
||||..||| .||..| || |.||. ||.|. |
APEILRGIPYDPKWYDVWSMGVILYIMVCGCMP
S_TKc 86997.m00251.AA S_TKc 19-257 23 7.3e-14 26.38 SMART 1-231 (231) Show / Hide 
Range on Protein: 19-257
Range on HMM: 1-231/231
Sequence Identity: 23% (60 aa)

YNVIKPMFSIGQNTYIEVQHRQHNQFFVCKITESPKIFEIENKILSRISHKNIIKVFEKFQEKQFNFTILEHFMP--VSLEKIGV----------IPKEQ
| ....  . .  .   ..|.  .. . .||    . .. | .||..  |.||.| .. ||. .. . ..|.      .| .. .          .|  .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H

IRMYSLQILCALEHCSSYGIYIGNLSPKTIFIDKYGMIKFVDFQHAMLIPKRYCTRFSITTQFPAPEIVQGIPFNPKAADMWSIGIILFYMVNGTYPCKE
.| |  ||.||||.| | ||    | |  |..|.   ||  ||  | ..     | |  |  . |||..   .......|.||.|.||. |. |  |   
ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP-

FTNAEEYMASVENIKSIFQFNEDMLHADILINLFQTDPNIRATLEDVRK---------VF
     ....  ..|.       .    |.. ...| ||. | |  .. .          |
-----QMQMMFKKIG-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 86997.m00251.AA GIN4 62-206 29 1.6e-13 39.14 In-house 87-237 (293) Show / Hide 
Range on Protein: 62-206
Range on HMM: 87-237/293
Sequence Identity: 29% (44 aa)

ILSRISHKNIIKVFEKFQEKQFNFTILEHFMPVSLEKI----GVIPKEQIRMYSLQILCALEHCSSYGIYIGNLSPKTIFIDKYGM-IKFVDFQHAMLIP
|.  ||| |...... . ...  . .||      |  .    | .|      |  ||.  .  | ...|    | |  . .|.    ||  ||  | |  
IMKLISHPNVMRLYDVWETNNDLYLVLEYAEKGELFNYLVDHGPLPEREAIHYFRQIIIGVSYCHAFNICHRDLKPENLLLDHKYNRIKIADFGMAALET

KRYCTRFSITT-QFPAPEIVQGIPFNPKAADMWSIGIILFYMVNGTYPCKE
.    . |     . ||||| |||..  |.|.|| |.||| .. |  |  |
DNKLLETSCGSPHYAAPEIVMGIPYHGFASDVWSCGVILFALLTGHLPFDE
Kinase 86997.m00251.AA CAMK 171-203 32 1.6e-13 39.19 In-house 288-333 (425) Show / Hide 
Range on Protein: 171-203
Range on HMM: 288-333/425
Sequence Identity: 32% (15 aa)

APEIVQG-------------IPFNPKAADMWSIGIILFYMVNGTYP
|||...|             .|  ....||||.|.||. |. |..|
APEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPP
Kinase 86997.m00251.AA MARK 166-213 36 1.7e-13 40.62 In-house 168-217 (262) Show / Hide 
Range on Protein: 166-213
Range on HMM: 168-217/262
Sequence Identity: 36% (18 aa)

TTQFPAPEIVQGIPFNPKAADMWSIGIILFYMVNGTYPCKEFT--NAEEY
|  . ||||... | . ...|.|| |..|..|| |..| .. |  . | |
TPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELY
Kinase 86997.m00251.AA SNRK 108-259 27 7.8e-13 38.09 In-house 102-254 (254) Show / Hide 
Range on Protein: 108-259
Range on HMM: 102-254/254
Sequence Identity: 27% (42 aa)

RMYSLQILCALEHCSSYGIYIGNLSPKT-IFIDKYGMIKFVDFQHA-MLIPKRYCTRFSITTQFPAPEIVQGIPFNPKAADMWSIGIILFYMVNGTYPCK
| |  ||. |.. |    .    | |   .| .| ||.|  ||  .    | .  . .     . ||||. |  .   | |.||.|.||. .| |  | .
RKYFCQIMHAIDYCHQLHVVHRDLKPENVVFFEKQGMVKLTDFGFSNKFMPGEKLETSCGSLAYSAPEILLGDSYDAPAVDIWSLGVILYMLVCGQAPFQ

EFTNAEEYMASVENIKSIFQFNEDMLHADILINLFQTDPNIRATLEDVRKVFGL
|  |  | .. . . |            |..  . . ||. ||.||..     .
E-ANDSETLTMIMDCKYTVPDHVSDECRDLIQSMLVRDPKKRASLEEIVSHSWV
Kinase 86997.m00251.AA ULK 171-203 35 7.1e-11 34.28 In-house 219-255 (329) Show / Hide 
Range on Protein: 171-203
Range on HMM: 219-255/329
Sequence Identity: 35% (13 aa)

APEIVQ----GIPFNPKAADMWSIGIILFYMVNGTYP
||.|.|    ..|.. . .|.||.|.|...|. | .|
APQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPP
Kinase 86997.m00251.AA ULK 171-203 37 1.5e-10 33.68 In-house 215-251 (324) Show / Hide 
Range on Protein: 171-203
Range on HMM: 215-251/324
Sequence Identity: 37% (14 aa)

APEIVQ----GIPFNPKAADMWSIGIILFYMVNGTYP
||.|.|    ..|.. . .|.||.|.|...|. | ||
APQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYP
Kinase 86997.m00251.AA Pkinase 59-121 24 1.6e-07 27.64 Pfam 50-124 (293) Show / Hide 
Range on Protein: 59-121
Range on HMM: 50-124/293
Sequence Identity: 24% (18 aa)

ENKILSRISHKNIIKVFEKFQEKQFNFTILEHFMPV----SLE------KIGVI--PKEQIRMYSLQILCALEHC
| .|. |..|.||.. .. |..|.    ..|. .      .|       . |..  . .....| .|||..||.|
EIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYC
Kinase 86997.m00251.AA Pkinase 171-257 18 6.4e-07 25.54 Pfam 179-293 (293) Show / Hide 
Range on Protein: 171-257
Range on HMM: 179-293/293
Sequence Identity: 18% (22 aa)

APEIVQGIPFNPKAADMWSIGIILFYMVNGTYPCKEF----TNAEEYMASVENIKSIFQFNED-----------------------MLHADILINLFQTD
|||...| .  ....||||.|.||..|..|  |...     . ....   ... . .. |...                           |.. .... |
APEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKD

PNIRATLEDVRKV--F
|. | | |.. .   |
PKKRPTAEQILQHPWF
Kinase 86997.m00251.AA CAMKL 61-83 26 0.000645 8.22 In-house 64-89 (297) Show / Hide 
Range on Protein: 61-83
Range on HMM: 64-89/297
Sequence Identity: 26% (7 aa)

KILSRIS---HKNIIKVFEKFQEKQF
.|.....   |.|||| .| .. ...
QIMKMLNIGKHPNIIKLYEVIETPEH
Kinase 86997.m00251.AA MARK 59-90 31 0.002606 6.87 In-house 49-83 (262) Show / Hide 
Range on Protein: 59-90
Range on HMM: 49-83/262
Sequence Identity: 31% (11 aa)

ENKILSRISHKNIIKVFEKFQ--EKQF-NFTILEH
| .|.....|.|||| |. ..  ..|   . |.|.
EIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEY
Kinase 86997.m00251.AA CAMK 35-126 12 0.011265 3.64 In-house 12-200 (425) Show / Hide 
Range on Protein: 35-126
Range on HMM: 12-200/425
Sequence Identity: 12% (24 aa)

EVQHRQHN------------QFFVCKI---------------------------------TESPKIFEIENKILSR-------ISHKNIIKVFEKFQE--
...|.. .            | . .||                                  .. | .. | .|...       ..|.|||| .| ..   
LCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKLYEVYEDPH

-----------------KQFNFTIL---EHFMPV----S-LEKI------------------GVIPKEQIRMYSLQILCALEHCSSYGI
                 ... . ..   |.          ...|                  | .. .. | |  ||..|...| | .|
YFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI