Gene 89799.m00090 (T.vaginalis)
89799.m00090
Species: T.vaginalis
Alias: TvagK0404, 89799.m00090
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| 89799.m00090.AA | Protein | None | 289 | None | Fasta, JSON |
| 89799.m00090.kin_dom | Protein Kinase Domain | None | 208 | None | Fasta, JSON |
Protein domains of 89799.m00090.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 89799.m00090.AA | AGC | 18-224 | 29 | 8.8e-123 | 318.89 | In-house | 55-395 (395) | Show / Hide |
Range on Protein: 18-224
Range on HMM: 55-395/395
Sequence Identity: 29% (102 aa)
VLTE------------KNIMMKIH----------HPFVVN-LCFAFQSDRK--VYLGLEYAS---------GG-ELFYYME---KVGVVPIDDARLYIAE
..|| .||..|.. |||.|. | ..||.... .|. .||.. || |||... | |. . . || |.||
TMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAE
-------IGLALSHLHK-YGIIYRD-LKPENVLFDADGHIKLTDFGLSKELN------------------------------------------------
| ||| .||. |||.|| |||||.|.|.|||||||||||.||..
MQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDT
---GTTGATTFCG--TPDYLAPEVVLQQEYGTKIDEWA--LGILTYEMIFGRTPFYNEN----------KSILLQDIV------ESEPFYP---------
.. ..|||| ||.|.|||.. || | |. ||.| |||..|..|||..| . . | | . .. .|
TRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPE
-EDADERIVDFMKRLLEKDPKKRAT----------FEEIKSHPFF
. .. .|..|.||.|||.|| . .||||.||.|
DRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
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| Kinase | 89799.m00090.AA | SGK | 18-224 | 45 | 2e-95 | 295.14 | In-house | 71-283 (283) | Show / Hide |
Range on Protein: 18-224 Range on HMM: 71-283/283 Sequence Identity: 45% (97 aa) VLTEK-NIMMKIHHPFVVNLCFAFQSDRKVYLGLEYASGGELFYYMEKVGVVPIDDARLYIAEIGLALSHLHKYGIIYRDLKPENVLFDADGHIKLTDFG ...|. .|. .. ||| ||| .||| . | |. ..|. |||.||.. . . | | || | ||| .|| .||. ||||||||||.| |..||..||||| IMAERNVILKNMKHPFIVNLHYAFQTKWKLYFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFG LSK-ELNGTTGATTFCGTPDYLAPEVVLQQEYGTKIDEWALGILTYEMIFGRTPFYNENKSILLQDIVESEPFYPEDADERIVDFMKRLLEKDPKKR--A |.| . ... .|||||| |||||| . |... | | ||.. |||..| |||. ||... . | .. | | .. ||.|||||| . LCKEGIKTNDTTFTFCGTPEYLAPEVLRKQPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGT T--FEEIKSHPFF |.|||.|||| KRDFMEIKNHPFF |
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| Kinase | 89799.m00090.AA | Akt | 18-224 | 44 | 7.5e-95 | 303.63 | In-house | 47-264 (264) | Show / Hide |
Range on Protein: 18-224 Range on HMM: 47-264/264 Sequence Identity: 44% (97 aa) VLTEKNIMMKIHHPFVVNLCFAFQSDRKVYLGLEYASGGELFYYMEKVGVVPIDDARLYIAEIGLALSHLHKYGIIYRD-LKPENVLFDADGHIKLTDFG ..||.|| .. |||.||| ..||. | |. ..|..||||||.. . .. . | || |.||| ||. |||. .||||| |||||.| |.||||.||||| TKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSEDRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFG LSK-E-LNGTTGATTFCGTPDYLAPEVVLQQEYGTKIDEWA-LGILTYEMIFGRTPFYNENKSILLQDIVESEPFYP--EDADERIVDFMKRLLEKDPKK |.| . . . ..|||||| |||||. ... .. . | |. ||...|||..|| ||||... . . | ... .| . . |. ..||.||||| LCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKK RA-----TFEEIKSHPFF | . .|||.||.| RLGGGPNDAQEIKRHPWF |
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| Kinase | 89799.m00090.AA | RSK | 3-224 | 38 | 1.6e-83 | 283.79 | In-house | 31-278 (278) | Show / Hide |
Range on Protein: 3-224 Range on HMM: 31-278/278 Sequence Identity: 38% (95 aa) QIHKKSVIN-DVDGCSVLTEKNIMMKIH-HPFVVNLCFAFQSDRKVYLGLEYASGGELFYYMEKVGV---VPIDDARLYIAEIGLALSHLHKYGIIYRDL ...|. ... ..| ..|| ||.. . |||.|.| ||| . |.|| .|| .|||||. .| . |.|. |.||| ||..|||. |||.||| VLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDL KPENVLFDA---DGHIKLTDFGLSKE-LNG-TTGATTFCGTPDYLAPEVVL---QQE-YGTKIDEWALGILTYEMIFGRTPFYN---ENKSILLQDIVES ||||.|.| .|||||||||..|. . . . |||.| .|.|||.. ||. .. | | ||.| ||| .|..||.. .|.. ... | . KPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKG E--PFYP--EDADERIVDFMKRLLEKDPKKRAT-----FEEIKSHPFF . . | . . |. ...|..||.|| . ||||.||.| KFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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| Kinase | 89799.m00090.AA | AktR | 18-224 | 43 | 1.5e-81 | 277.23 | In-house | 47-268 (268) | Show / Hide |
Range on Protein: 18-224 Range on HMM: 47-268/268 Sequence Identity: 43% (96 aa) VLTEKNIMM-KIHHPFVVNLCFAFQSDRKVYLGLEYASGGELFYYMEKVGVVPIDDARLYIAEIGLALSHLHKY-GIIYRDLKPENVLFDADGHIKLTDF ..||.||| .. ||| |.| ..||...| .. .|| |||||.. | . ..|| |.|.| ||| .||. |||||||||| | | |||.|.||| TITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSEEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDF GLSK--ELN-GTTGATTFCGTPDYLAPEVVLQ-QEYGTKIDEWALGILTYEMIFGRTPFYNENKSILLQDIVESE---PFYPEDADERIVDFMK-RLLEK |||| . . |..||||| |.|||.... . .. .| ||.||. |||..| .|||..|. ...| | ... . ||.. . |. . .|| | GLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCK DPKKRAT-----FEEIKSHPFF .|.|| . .|||||||.| NPNKRLGYYCNGWEEIKSHPWF |
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| Kinase | 89799.m00090.AA | PKA | 18-224 | 42 | 3.2e-80 | 272.83 | In-house | 46-263 (263) | Show / Hide |
Range on Protein: 18-224 Range on HMM: 46-263/263 Sequence Identity: 42% (93 aa) VLTEKNIMMKIHHPFVVN-LCFAFQSDRKVYLGLEYASGGELFYYMEKVGVVPIDDARLYIA-EIGLALSHLHKYGIIYRDLKPENVLFDADGHIKLTDF |..||||.. |.|||.|. . . || ||. |. .||..|||.|.|. |.| . ..|..|.| .| ||| ||. |||||||||| | | .||||.||| VHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNPHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDF GLSKELNGTTGATTFCGTPDYLAPEVVLQQ-EYGTKIDEWALGILTYEMIFGRTPFYNE--NKSILLQDIVESEPFYPEDADERI---VDFMKRLLEKDP | .|.. . | ||||.|||||... .| .| |||||| ||| .| .|||.. .. . . |.. . ..|. | . |. |.||..|. GFAKKVDD--RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDL KKRA-TFEE----IKSHPFF .|| .... || |..| TKRYGNMKNGVNDIKNHKWF |
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| S_TKc | 89799.m00090.AA | S_TKc | 2-224 | 35 | 6.7e-76 | 259.39 | SMART | 16-231 (231) | Show / Hide |
Range on Protein: 2-224
Range on HMM: 16-231/231
Sequence Identity: 35% (88 aa)
HQIHKKS--------VINDVDGCSVLTEKNIMMKIHHPFVVNLCFAFQSDRKVYLGLEYASG--GELFYYMEKVGV------VPIDDARLYIAEIGLALS
.. ..|. .|. .... | .|..| |||..|.| .||. ..|. .||..| |.|| |..| | | .|| |...| .||
YKCRHKKTGRIVAIKIIK----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALE
HLHKYGIIYRDLKPENVLFDADGHIKLTDFGLSKELNGTTGATTFCGTPDYLAPEVVLQQEYGT-KIDEWALGILTYEMIFGRTPFYNENKSILLQDIVE
..|. |||.|||||||.|.| |||..||||...| |||||||.|.||||. ||. |.| |..|.. |||. |..||. . ... |.
YCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-
SEPFYPEDADERIVDFMKRLLEKDPKKRATFEEIKS-------HPFF
.. ||....|.|||.|| | |. ||.|
---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
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| Kinase | 89799.m00090.AA | Pkinase | 24-224 | 34 | 1.9e-74 | 258.44 | Pfam | 53-293 (293) | Show / Hide |
Range on Protein: 24-224
Range on HMM: 53-293/293
Sequence Identity: 34% (85 aa)
IMMKIHHPFVVNLCFAFQSDRKVYLGLEYASGG----ELFYYME--KVGVV--PIDDARLYIAEIGLALSHLHKYGIIYRDLKPENVLFDADGHI----K
|| ...||..| | .|......|. .||. || .|| |.. . |.. . .... |. .| .| ..|. |||.|||||||.|.| .||| |
IMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVK
LTDFGLSKE--LNGTTGATTFCGTPDYLAPEVVL-QQEYGTKIDEWALGILTYEMIFGRTPFYNE------NKSILLQDIVESEPFYPEDAD--------
..||||.| . . .|||||||.|.||||.. .|.||.|.| |..|.. |||..||.||... .. ... | . .. .... .
ICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFF
-------------ERIVDFMKRLLEKDPKKRATFEEIKSHPFF
| ||.|..|.|||||| |.|.|. ||.|
RHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
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| Kinase | 89799.m00090.AA | CAMK | 4-224 | 21 | 5.4e-74 | 237.62 | In-house | 39-425 (425) | Show / Hide |
Range on Protein: 4-224
Range on HMM: 39-425/425
Sequence Identity: 21% (83 aa)
IHKKSVIN-------------------------DVDGCSVLTEKNIMMK-------IHHPFVVNLCFAFQS-------------------DRKVYLGL--
| || . . ..| .|. | .||.| ..|| ...| .... |...|. .
IDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEI
-EYASGGEL----FYYMEKV---------------GVVPIDDARLYIAEIGLALSHLHKYGIIYRDLKPENVLFDAD-----------------GHIKLT
||.||||| | | . | .. ..|| |. | |. ..|. .|. |||||||.|.| . . ||..
MEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKII
DFGLSKELNG------------------------TTGATTFCGTPDYLA-PEVVLQ--------------QEYGTKIDEWALGILTYEMIFGRTPFYNE-
|||....... . .|||||| | | |||... . || |.| |..|...| | |. ||| .
DFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDC
------------NKSILLQDIVESE-PFYPEDADE-----------------------RIVDFMKRLLEKDPKKRATFEEIKSHPFF
| . |.. | . . |.|. .. |. ...|..||.||.| |....||..
DNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | 89799.m00090.AA | PKC | 4-224 | 40 | 1.1e-73 | 238.14 | In-house | 32-262 (262) | Show / Hide |
Range on Protein: 4-224 Range on HMM: 32-262/262 Sequence Identity: 40% (93 aa) IHKKSVINDVDGCSVLTEKNIM-MKIHHPFVVNLCFAFQSDRKVYLGLEYASGGELFYYMEKVGVVPIDDARLYIAEIGLALSHLHKYGIIYRDLKPENV . | .| | | ...||| .. ||| ..| ||. . . .|| || | . . ... . || | ||| .|| ||. |||||||| .|| LKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEEHARFYAAEIICALQFLHEKGIIYRDLKLDNV LFDADGHIKLTDFGLSKE-LNGTTGATTFCGTPDYLAPEVVLQQEYGTKIDEWALGILTYEMIFGRTPFYNENKSILLQDIVESEPFYPEDADERIVDFM | |..||||..|||..|| ... . ..||||||||.|||.. |||| .| ||.|.| ||| |. || |. | | | . .|.|| . ...|. . LLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPFHGEDEDELFQSIMHDNPHYPRWLSKEAVSIC KRLLEKDPKKRATF--------EEIKSHPFF | ...|.|.|| ..|..|||| KGFMTKNPEKRLGCHPQQEEGEQDIREHPFF |
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| Kinase | 89799.m00090.AA | p70 | 21-224 | 39 | 1.5e-72 | 247.33 | In-house | 78-299 (299) | Show / Hide |
Range on Protein: 21-224 Range on HMM: 78-299/299 Sequence Identity: 39% (88 aa) EKNIMMKIHHPFVVNLCFAFQSDRKVYLGLEYASGGELFYYMEKVGVVPIDDARLYIAEIGLALSHLHKYGIIYRDLKPENVLFDADGHIKLTDFGLSKE | || . |||.. | .||| . | || ||| .|||||. |. |. . | |. | .|| .|| |||. |||||||||||.. .. ||..||||||.|| ERNILEEVKHPFICDLHYAFQTNGKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKE -LNGTTG----------ATTFCGTPDYLAPEVVLQQEYGTKIDEWALGILTYEMIFGRTPFYNENKSILLQDIVESE--PFYPEDADERIVDFMKRLLEK ... . |||||. | |||... .. .| |.||.| | | | || ||. | . | . | |.|| . SIHDGAVDEEDPENVNATHTFCGTIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKR DPKKRAT-----FEEIKSHPFF .|..| . ..|..|||| HPTQRWGAGPEDAADIQEHPFF |
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| Kinase | 89799.m00090.AA | Ciliate-E2 | 21-224 | 29 | 1.9e-72 | 246.98 | In-house | 82-365 (365) | Show / Hide |
Range on Protein: 21-224 Range on HMM: 82-365/365 Sequence Identity: 29% (88 aa) EKNIMMKIHHPFVVNLCFAFQ--SDRKVYLGLEYASGGELFYYME-------------------KVGVVPIDDAR-------LYIAEIGLALSHLHKYG- ||||. .. ||..... .|| .| ..|| .||..||.||.|.. ... . .. |||.| ||| .||. . EKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN IIYRDLKPENVLFDADGHIKLTDFGLSKELN----------------------GTTG----------ATTFCGTPDYLAPEVVL---------QQEYGTK ||.||.||||.|| ||..||||||... .|.| . |.|||| |.|||.. |..|..| IIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYK IDEWALGILTYEMIFGRTPFYNENKSILLQDIVESEPFYPEDADERIV---------------DFMKR----LLEKDPKKRAT-FEEIKSHPFF .| |.||.. |||.||..|| . |. ..| ..|.. .| . .. |..|. .|.|||.|| | .|.|. ||.| CDIWSLGVILYEMLFGKPPF---QQQIKQCKIDFPCPEWQKD-TQ-CIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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| Kinase | 89799.m00090.AA | S_TK_X | 225-285 | 27 | 1.9e-14 | 55.27 | SMART | 1-79 (79) | Show / Hide |
Range on Protein: 225-285 Range on HMM: 1-79/79 Sequence Identity: 27% (22 aa) EGVDWDAILG--REYMPSYIPQIK----DRFSTQNFDPEFTNEIAVDSFVTPGMTDFGN------------IAGFSFVQ |.|||... .|. | ..|.|| . . | |||||||.| .... . |.... . .||..| RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF |
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| Kinase | 89799.m00090.AA | TyrKc | 4-224 | 20 | 1.3e-13 | -2.71 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 4-224 Range on HMM: 1-280/280 Sequence Identity: 20% (58 aa) IHKKSVI-----------------------NDVDGCSVLTEKNIMMKI--HHPFVVNLCFAFQSD-------RKVYLGLEYASGGELFYYMEKVGV-VPI |... .. .| . | .||.|. ||| .|.| . .. ... .||...| | | | . .. ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCM DDARLYIAEIGLALSHLHKYGIIYRDLKPENVLFDADGHIKLTDFGLSKELNGT-----TGATTFC----GTPD-----YLAPEVVLQQEYGTKIDEWAL .| . | ..||. ..| ||| |.| ......| .|||||... . . |. . .|||. .. || | |. KDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSF GILTYEMI-FGRTPFYN------ENKSILLQDIVESEPFYPED--------ADERIVDFMKRLLEKDPKKRATFEEIKSHPFF |.. .|. .| .| .. .|. .. . . |.. . . . . ||. . ||..| ||.|| | .| GVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |
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| Kinase | 89799.m00090.AA | Pkinase_C | 244-287 | 33 | 2e-06 | 26.18 | Pfam | 1-46 (46) | Show / Hide |
Range on Protein: 244-287 Range on HMM: 1-46/46 Sequence Identity: 33% (16 aa) QIKDRFSTQNFDPEFTNEIAVDSF----VTPGMTDFGNIAGFSFVQTG |.|.. |.|||||||.| ..|.. ..|. . . ||..| QVKSPTDTSNFDPEFTDEPPMDTPPDWRMSSGDQE--PFRGFTYVNPD |
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| Kinase | 89799.m00090.AA | Pkinase_Tyr | 19-224 | 25 | 7e-06 | 20.53 | Pfam | 51-270 (270) | Show / Hide |
Range on Protein: 19-224 Range on HMM: 51-270/270 Sequence Identity: 25% (56 aa) LTEKNIMMKI-HHPFVVNLCFAFQ-SDRK--VYLGLEYASGGELFYYMEK----VGVVPIDDARLYIAEIGLALSHLHKYGIIYRDLKPENVLFDADGHI . | .||... ||| .|.| . .. .|. .||. .| | | | . ... | . ..| ....|. ..| ||| |.| . .... MREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVV KLTDFGLSKEL----NG-TTGATTFCGTPDYLAPEVVLQQEYGTKIDEWALGILTYEMIF-GRTP-FYNENKSILLQDI-VESEPFY-PEDADERIVDFM | .||||.. . . ... . .|||. .. || | |. |.| .|.. |..| ... . ... | . . ||.. . | | | KICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLM KRLLEKDPKKRATFEEIKSHPFF |. ..||..| ||.|| | .. KQCWHYDPEDRPTFSEI--HEQL |
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