Gene 89397.m00076 (T.vaginalis)
89397.m00076
Species: T.vaginalis
Alias: TvagK0546, 89397.m00076
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
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89397.m00076.AA | Protein | None | 343 | None | Fasta, JSON |
89397.m00076.kin_dom | Protein Kinase Domain | None | 253 | None | Fasta, JSON |
Protein domains of 89397.m00076.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 89397.m00076.AA | CAMK | 15-273 | 19 | 3.2e-63 | 202.29 | In-house | 1-421 (425) | Show / Hide |
Range on Protein: 15-273 Range on HMM: 1-421/425 Sequence Identity: 19% (82 aa) HVATTANSQVFLATKVNDS--SF--------KTYIMKIVQRT--------------------------HRNPKAISNLEGEIRIMQK-------IDHPSI . . ..|.|.. |. . . .||. .. .|.|| |.. ||.||.| .||| | TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI IKLLDVIYD-------------------QDEVTLVI---EYGENG----DLVKYLNEK---------------GVIDLNTTLSIMRDIFDAIAYLHARNI |||..|. | .... .| || ..| || |. |. | .. . ..| | .|..|.| .|| IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI AHRDIKLENIVITAE-----------------GKPKLIDLGLSKEYINNE-------NPNNEPLQER-----SGKILKTTFCGTYEYMA-PELFEKH--- .|||.|.||| .. .. |.|| |...... .| . ..| . .. . .||||| |||| ||.... VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC ---------VFYDPFAADVWAAGMCLYVLYNGFFPWVDS--------------EFGALDQIRRTKIS-IPKTWPAI-----------------------I |.....|.|..| ||.. |..|. .. . . .|.. | . .|. .. | NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQEC RRVVSMSLEIDPCKRAKAKDILN . .. |. || ||......|| KDLIRKMLQVDPEKRMTIEQCLN |
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S_TKc | 89397.m00076.AA | S_TKc | 10-279 | 24 | 5.6e-62 | 213.14 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 10-279 Range on HMM: 1-231/231 Sequence Identity: 24% (70 aa) YIPYSHVATTANSQVFLATKVNDSSFKTYIMKIVQRTHRNPKAISNLEGEIRIMQKIDHPSIIKLLDVIYDQDEVTLVIEYGEN--GDLVKYLNEKGV-- | .. | ..|....... . . . .||. ... ||.|..| .|| |.||.||..| |.. .| || .. ||| .|. ..| YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG ----IDLNTTLSIMRDIFDAIAYLHARNIAHRDIKLENIVITAEGKPKLIDLGLSKEYINNENPNNEPLQERSGKILKTTFCGTYEYMAPELFEKHVFYD .. .. ..|. |..|..|.| ..| |||.| ||| .. |..| ||.... |||||| .|||||.. |. LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------------------TTFCGTPWYMAPEVL----GYG PFAADVWAAGMCLYVLYNGFFPWVDSEFGALDQIRRTKISIPKTWPAIIRRVVSMSLEIDPCKRAKAKDILN-----EMDNFM ....|.|. | .|| .. | |. .. ...|. . . .. |. || || | ..|. .. .. KCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 89397.m00076.AA | CAMKL | 40-273 | 26 | 3.4e-55 | 174.52 | In-house | 30-293 (297) | Show / Hide |
Range on Protein: 40-273 Range on HMM: 30-293/297 Sequence Identity: 26% (74 aa) MKIVQ--RTHRNPKAISN-----------LEGEIRIMQKID---HPSIIKLLDVIYDQDE------VTLVIEYGENGD--LVKYLNEK----GVIDLNTT .||. .. .|.. .| .. ||.||.... || ||||..||.... . || || ..|. | |. .. | .. . . IKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEA LSIMRDIFDAIAYLHARNIAHRDIKLENIVITAEG--KPKLIDLGLSKEYI-NNENPNNEPLQERSG-KILKTTFCGTYEYMAPELFEK-HVFYDPFAAD . | | .|..|.| ..|.|||||.||| .. | . |.|| |.| .|. . | . .||||...|||||.|.. . || ...| RRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPC-----------IFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVD VWAAGMCLYVLYNGFFPWVDS----------EFGALDQIRRTKISIPKTWPAIIRRVVSMSLEIDPCKRAKAKDILN .|..| ||.. | .|. | .. . . ... |.. . |. . |. .| ||.....|.| IWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMN |
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Kinase | 89397.m00076.AA | MARK | 41-279 | 32 | 1.2e-52 | 170.46 | In-house | 30-262 (262) | Show / Hide |
Range on Protein: 41-279 Range on HMM: 30-262/262 Sequence Identity: 32% (82 aa) KIVQRTHRNP-KAISNLEGEIRIMQKIDHPSIIKLLDVIY--DQDE-VTLVIEYGENGDLVKYLNEK--GVIDLNTTLSIMRDIFDAIAYLHARNIAHRD ||.... |. ....|.. ||.||.|.||| ||||..|| . . |. || ..|.| |. .. | . . . | | | |. |.| .||.||| KIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRD IKLENIVITAEG--KPKLIDLGLSKEYINNENPNNEPLQERSGKILKTTFCGTYEYMAPELFEKHVFYDPFAADVWAAGMCLYVLYNGFFPWVDSE--FG ||.||| | ..| . |.|| |.| . .... .|||||..|||||.|.| || ...|.|. | ||.. | ||. .. . IKPENILIDENGNHNIKIIDFGFSICIPPGQK--------------LNTFCGTPPYMAPEIFLKKP-YDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYK AL-DQIRRTKISIPKTWPAIIRRVVSMSLEIDPCKRAKAKDILNEMDNFM | .|.| | .|| .. .| .. | ..| .|.....|. .. .| ELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIM--KHPWM |
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Kinase | 89397.m00076.AA | Pkinase | 20-275 | 24 | 7.3e-52 | 183.42 | Pfam | 11-293 (293) | Show / Hide |
Range on Protein: 20-275 Range on HMM: 11-293/293 Sequence Identity: 24% (72 aa) ANSQVFLATKVNDSSFKTYIMKIVQRTHRNPKAISNLEG--EIRIMQKIDHPSIIKLLDVIYDQDEVTLVIEYGENG----DLVKYLN--EKGVI--DLN . ..|......... .. .||. . |.... .. ||.||....|| |..|.|. .| |.. .| || |.| || |. ..|.. . . SFGCVYKCHHKGTGK--IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEW TTLSIMRDIFDAIAYLHARNIAHRDIKLENIVITAEGKP----KLIDLGLSKEYINNENPNNEPLQERSGKILKTTFCGTYEYMAPELFEKHVFYDPFAA . ..|. |. ...|.|...| |||.|.||| | .| . |..| ||.| . . .. ||||||..|||||. . |.. .. ECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-----------Y-NNS--MTTFCGTPWYMAPEVIR-GGQYYGPKV DVWAAGMCLYVLYNGFFPWVDS-------EFGALDQIRRTKISIPKTWP---------------------AIIRRVVSMSLEIDPCKRAKAKDILNE--M |.|..| || ...| .|. .. . ...|...... . |. . ... |. || || |..||. . DMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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Kinase | 89397.m00076.AA | Ciliate-E2 | 22-273 | 22 | 1.6e-47 | 161.15 | In-house | 13-361 (365) | Show / Hide |
Range on Protein: 22-273 Range on HMM: 13-361/365 Sequence Identity: 22% (81 aa) SQVFLATKVNDSSF---------------------KTYIMKIVQRTHRNPKAISNLEGEIR-------------IMQKIDHPSIIKLLDVIY--DQDEVT ..|..... .. | | |||.. ... ..|.. . ..| |.....|| |||. .. . |.. . GSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMK--KNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKDDNNIY LVIEYGENGDLVKYLNEK-----------GVIDLNTTLSIMRDIFD---------------AIAYLHARN-IAHRDIKLENIVITAEGKPKLIDLGLSKE || || . ||| .|.... . .... . ||. |.. |. ||| .| | |||||.|||.. .|.||.||||. LVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKK YINNENPNNEPLQERSGKILKT--------------------TFCGTYEYMAPELFE-KH------VFYDPFAADVWAAGMCLYVLYNGFFPWVDSEFGA | .... . . .|.. .. |.|||..||||| .. | . ...|.|..|..|| . | .|. YDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF------- LDQIRRTKISIP------------------KTWPAIIRRVVSM----SLEIDPCKRAK-AKDILN ..|| ||..| | |. . |. || || ...||| QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN |
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Kinase | 89397.m00076.AA | Ciliate-E2-Unclassified | 20-223 | 22 | 1.4e-45 | 156.12 | In-house | 11-269 (352) | Show / Hide |
Range on Protein: 20-223 Range on HMM: 11-269/352 Sequence Identity: 22% (58 aa) ANSQVFLATKVND---------SSFKTYIMKIVQRTHRNPKAISNLEGEIR-------------IMQKIDHPSIIKLLDVIYDQDEVTLVIEYGENGDLV ....|... . .. .... | .|.... . . . . . . .. |.. ..|| |.|.... |.. . .| || |.||| GFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLW KYLNEKGV-----------------IDLNTTL-----SIMRDIFDAIAYLHARN-IAHRDIKLENIVITAEG---KPKLIDLGLSKEYINNENPNNEPL- .|..... .. . .. ... | ... ||| | | |||||.|||... .| ..|.||.|.||.|..|.| . QYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCD-TNQQ --QERSGKILKTTFCGTYEYM----APELFEKHVFYDP--FAADVWAAGMCLYVLYNGFFP . . . . .|||||..|| |||..... ... ...|.|. |..|| . | .| QKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYP |
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Kinase | 89397.m00076.AA | AGC | 22-215 | 23 | 7.3e-41 | 102.17 | In-house | 13-296 (395) | Show / Hide |
Range on Protein: 22-215 Range on HMM: 13-296/395 Sequence Identity: 23% (67 aa) SQVFLATKVND----SSFKTYIMKIVQRTH---RNPK-AISNLEGE------------IRIMQKID----------HPSIIK-LLDVIYDQDE--VTLVI ..|.|. |... .. | | ||... | .. | . . | .|..|.. || |.| | |.| . .| GKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSFQDKDHTYLYFVM EYGE---------NG-DLVKYLN---EKGVIDLNTTLSIMRD-------IFDAIAYLHA-RNIAHRD-IKLENIVITAEGKPKLIDLGLSKEYINNENP- || . | .| .| .|. | ... .. | |. ||| ..| ||| .|.|||.....| || | ||.|| .|.... EYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKG ---------------------------NNEPLQER---------SGKILKTTFCG--TYEYMAPELFEKHVFYDPFAADVWA--AGMCLY .|. .... ... . .|||| | |||||| . |. .|.| |. | ..| QQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YG-KACDWWSFGLGCLMY |
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Kinase | 89397.m00076.AA | ULK | 59-244 | 22 | 4.6e-34 | 116.35 | In-house | 60-291 (329) | Show / Hide |
Range on Protein: 59-244 Range on HMM: 60-291/329 Sequence Identity: 22% (55 aa) EIRIMQKID--------HPSIIKLLDVIYDQDE--VTLVIEYGENGDLVKYLNEKGV----------IDLNTTLSIMRDIFDAIAYLHARNIAHRDIKLE ||.||.|.. || |.||.|. ..... . .. || . ||| .|..... . . .......| . .|| .|| |||||.. EIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQ NIVITA-EGK-----------PKLIDLGLSKEYINN--ENP-NNEPL-QERSGKILKTT-FCGTYEYMAPELFE---KHVFYDPFAADVWAAGMCLYVLY || |. .| |. | |..| |. |. . . . . .||| ||||.... .. |. . .|.| |. .| . NILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNE---------KRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEML NGFFP---WVDSEF-----GALDQ-------IRRTKISIPK | | | ... ... |. ... .|| YGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPK |
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Kinase | 89397.m00076.AA | ULK | 59-228 | 25 | 9.3e-32 | 109.98 | In-house | 60-258 (324) | Show / Hide |
Range on Protein: 59-228 Range on HMM: 60-258/324 Sequence Identity: 25% (54 aa) EIRIMQKID---HPS--IIKLLDVIYDQDE--VTLVIEYGENGDLVKYLN---------EKGVIDLNTTLSIMRDIFDAIAYLHARNIAHRDIKLENIVI ||.||.|.. || |.||.|. ..... . .. || . ||| .|.. ||. . . .......| . .|| .|| |||||..|| | EIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILI TA-EGK-----------PKLIDLGLSKEYINNENPNNEPLQERSGKILKTTFC------GTYEYMAPELFE---KHVFYDPFAADVWAAGMCLYVLYNGF . .| |. | |..| ||. . . .|.. || ||||.... .. |. . .|.| |. .| . | HNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNN----------MEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGK FP---WVDSE | | .. YPFFSW-FND |
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Kinase | 89397.m00076.AA | TKL | 59-275 | 19 | 4.1e-31 | 109.26 | In-house | 75-364 (364) | Show / Hide |
Range on Protein: 59-275 Range on HMM: 75-364/364 Sequence Identity: 19% (57 aa) EIRIMQKIDHPSIIKLLDVIYDQDE-------------VTLVIEYGENGDLVKYLNEKGVIDLNTTLSIMRDIFDAIAYLHARN--------IAHRDIKL ||..| ...|| |.... . . . .| || ..|.| ||. .. ......|| ...|||..| |.|||.| EIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKS ENIVITAEGK--------------PKLIDLGLSKEYINNENPNNEPLQER------SGKILKTTFCGTYEYMAPELFEKHVFYDP--------------F .|| . .. .|. |.|||.. ...| | .. ... . | |||. .||||..... .|. KNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSE AADVWAAGMCLYVLYNGFFPWVDSEFG------------ALDQIRRTKISIP------------KTWPAIIRRVVSMSLEIDPCKRAKAKDILNEM ..||.. |..|. .. . |. | . ... .. . || .. | ... . . || || ...|| .. KCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL |
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Kinase | 89397.m00076.AA | RSK | 36-279 | 23 | 3.6e-29 | 103.22 | In-house | 25-278 (278) | Show / Hide |
Range on Protein: 36-279 Range on HMM: 25-278/278 Sequence Identity: 23% (64 aa) KTYIMKIVQRTHRNPKA--ISNLEGEIRIMQKID-HPSIIKLLDVIYDQDEVTLVIEYGENGDLVKYLNEKGV---IDLNTTLSIMRDIFDAIAYLHARN . | ||.... . ... . |..|.. . || |..| .. ..... |. || . |.| . | ... .. .. .|. | |. .|| . QIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQG IAHRDIKLENIVITA---EGKPKLIDLGLSKEYINNENPNNEPLQERSG-KILKTTFCGTYEYMAPELFE---KHVFYDPFAADVWAAGMCLYVLYNGFF | |||.|.|||. . || ||.| |..|. | . . |||.| ||||||. . . .| |.|.| | .| . |. IIHRDLKPENILYDDESNEGHIKLTDFGFCKQF-------------RCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDK-ACDWWSLGVLMYEMLTGCP PWVD----SEFGALDQIRRTK--ISIP--KTWPAIIRRVVSMSLEIDPCKRAK-----AKDILNEMDNFM | . ...|.. | ..| .. . . ... |. || || . |..|.. . .. PFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHP--WF |
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Kinase | 89397.m00076.AA | TyrKc | 18-275 | 20 | 1.2e-13 | -2.27 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 18-275 Range on HMM: 1-280/280 Sequence Identity: 20% (60 aa) TTANSQ--------VFLATKVNDSSFKTYIMKIVQRTHRNPKAISNLEGEIRIMQKI--DHPSIIKLLDVIYDQ-------DEVTLVIEYGENGDLVKYL | . . |...| . | .. . . . |.||| |. .|| |..|. |. .| . . .| || ..||| .|| ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL -NEKGVIDLNTTLSIMRDIFDAIAYLHARNIAHRDIKLENIVITAEGKPKLIDLGLSKEYINN-ENPNNEPLQERSGKILKTTF--CGT----YEYMAPE . .. . . . ||.. .| . .||| .|. |||. |. ..... | | |||.. . .. |.. ... .| . |||| RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG-------ESKDYYRKKEHKGGKTMLPIRWMAPE LFEKHVFYDPFAADVWAAGMCLY-VLYNGFFPWVD------SEFGALDQIRRT-KISIPKT--------WPAIIRRVVSMSLEIDPCKRAKAKDILNEM . ...| .. |||. | |.. .. .| |. . | . .. .... .|. |. . .. .. . || .| ..| .. CINYGKFT--TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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Kinase | 89397.m00076.AA | Pkinase_Tyr | 59-135 | 29 | 3.9e-13 | 45.1 | Pfam | 53-137 (270) | Show / Hide |
Range on Protein: 59-135 Range on HMM: 53-137/270 Sequence Identity: 29% (25 aa) EIRIMQKI-DHPSIIKLLDVIY-DQDE--VTLVIEYGENGDLVKYLNE----KGVIDLNTTLSIMRDIFDAIAYLHARNIAHRDI |..|| .. .|| |..|. |.. ... . .| || ..||| .|| . |. ... . |.. ..| .. .||...|. |||. EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL |