Gene 84561.m00139 (T.vaginalis)
84561.m00139
Species: T.vaginalis
Alias: 84561.m00139, TvagK0956
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| 84561.m00139.AA | Protein | None | 357 | None | Fasta, JSON |
| 84561.m00139.kin_dom | Protein Kinase Domain | None | 128 | None | Fasta, JSON |
Protein domains of 84561.m00139.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 84561.m00139.AA | CMGC | 226-353 | 15 | 1.4e-16 | 50.08 | In-house | 293-513 (513) | Show / Hide |
Range on Protein: 226-353 Range on HMM: 293-513/513 Sequence Identity: 15% (34 aa) SPEQLLSTR----------WSYEIDIWQLGILFVELITG--------RKLFT-HNNR----------LLHYALIEKLGGQFPLFLLDESQ--------KS .|| ||. . ....||.| .| | |..|| . || |... . . ..| |. | .. ... .. . APEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT-WMIQKGKRHFNFCKHEE EIPIFRDGKCDIS------------MLDDECRKIYNS---FP-----TLENLIHN-------------------------------------DKALSFAQ |.| . . . ... |. .| || ...||. . ..|. . . EWPNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLK ATLCTDPSRRLLPLQLINHPFI |. ||..|. . | .||.. KMLQYDPDKRITAEQALQHPYF |
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| Kinase | 84561.m00139.AA | Pkinase | 226-353 | 17 | 4.8e-12 | 43.67 | Pfam | 179-293 (293) | Show / Hide |
Range on Protein: 226-353 Range on HMM: 179-293/293 Sequence Identity: 17% (24 aa) SPEQLL-STRWSYEIDIWQLGILFVELITGRKLFTHN----NRLLHYALIEKLGG-QFPLFLLDESQKSEIPIFRDGKCDISMLDDECRKIYNSFPTLEN .|| .. .. .....|.| .|... |...|| .| . | . ....|.. .| ... .. .| . ||. . ... APEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-------------F-HWTF- LIHNDKALSFAQATLCTDPSRRLLPLQLINHPFI .. ...| || ||..|. . |. .||.. HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | 84561.m00139.AA | Ciliate-E2 | 225-353 | 12 | 2.8e-11 | 34.95 | In-house | 254-365 (365) | Show / Hide |
Range on Protein: 225-353
Range on HMM: 254-365/365
Sequence Identity: 12% (20 aa)
QSPEQLL---------STRWSYEIDIWQLGILFVELITGRKLFTHNNRLLHYALIEKLGGQFPLFLLDESQKSEIPIFRDGKCDISMLDDECRKIYNSFP
..|| | .....|..||| ||... |...|. | .. . . .. ..
MAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------------------------------------------QQQIKQCKIDFPC
TL-------------ENLIHNDKALSFAQA----TLCTDPSRRLL-PLQLINHPFI
... . ... . . |. ||. |. . |..|||..
PEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
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| S_TKc | 84561.m00139.AA | S_TKc | 46-353 | 13 | 4.4e-11 | -14.32 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 46-353
Range on HMM: 1-231/231
Sequence Identity: 13% (45 aa)
YKILDLIESTNEYKSYFGIHQRQKFFVLIKFYYKSPTLLRKANIETEALTITNTIDLTHQYFVKYIGRYEYNLCPILIFQALGP---TLTKQMEFFNG--
|.||..| . | | ..| . . | || .|. | . | . ||... .. . ... .. .| . .. ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG
--LTFSLSTIRVFMWHLIHALELLHECKLI----------------------CGNLSTDTVSLLEDYVDQKGYVMKTGERSVQLRINSLSCASNGNIWHV
|. ..| .|. .. ||| .|. . | . |
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQL-------------------------------------------T
TSLTPERIQSPEQLLSTRWSY-EIDIWQLGILFVELITGRKLFTHNNRLLHYALIEKLGGQFPLFLLDESQKSEIPIFRDGKCDISMLDDECRKIYNSFP
| .|| | ... ..|.| .|... |...|. .| ......|.|
TFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP-----QMQMMFKKIG-----------------------------------------
TLENLIHNDKALSFAQATLCTDPSRRLLPLQLIN-------HPFI
. |..| . |. ||..|. .. . ||..
-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
|
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| Kinase | 84561.m00139.AA | Ciliate-E2-Unclassified | 221-353 | 20 | 1.1e-08 | 26.33 | In-house | 230-352 (352) | Show / Hide |
Range on Protein: 221-353 Range on HMM: 230-352/352 Sequence Identity: 20% (29 aa) PERIQSPEQLLSTRWS----YEIDIWQLGILFVELITGRKLFTHNNRLLHYALIEKLGGQFPLFLLDESQKSEIPIFRDGKCDISMLDDEC-RKIYNSFP | ....|| | . . |..||| ||... |...|. | ||. |. ||.. . .. ....| ... |... .. P-QYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWI-N---------------NA-----YRKQLYQNIKQKNIQFPK TLE-N--LIHNDKALSFAQ----ATLCTDPSRRLLPLQLINHPFI . . . ...| | . | .|. |. . |..|||.. FPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
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| Kinase | 84561.m00139.AA | CDK | 226-258 | 38 | 3e-06 | 15.69 | In-house | 187-225 (284) | Show / Hide |
Range on Protein: 226-258 Range on HMM: 187-225/284 Sequence Identity: 38% (15 aa) SPEQLL-STRWS--YEIDIWQLGILFVELIT---GRKLF .|| || |.. | .||.| .| |.|..| .. || APELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLF |
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| Kinase | 84561.m00139.AA | DYRK1 | 226-262 | 45 | 4e-06 | 16.79 | In-house | 171-207 (321) | Show / Hide |
Range on Protein: 226-262 Range on HMM: 171-207/321 Sequence Identity: 45% (17 aa) SPEQLLSTRWSYEIDIWQLGILFVELITGRKLFTHNN ||| || .... .||.| || . ||. || ||. | SPEVLLGIEYDMAIDMWSLGCILVEMHTGEPLFSGSN |
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| Kinase | 84561.m00139.AA | Ciliate-D1 | 240-258 | 36 | 1e-05 | 20.02 | In-house | 1-19 (19) | Show / Hide |
Range on Protein: 240-258 Range on HMM: 1-19/19 Sequence Identity: 36% (7 aa) DIWQLGILFVELITGRKLF |||..|... |...|.. | DIWSFGCILYEMLFGQPPF |
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| Kinase | 84561.m00139.AA | DyrkP | 227-262 | 41 | 2.9e-05 | 12.56 | In-house | 174-209 (323) | Show / Hide |
Range on Protein: 227-262 Range on HMM: 174-209/323 Sequence Identity: 41% (15 aa) PEQLLSTRWSYEIDIWQLGILFVELITGRKLFTHNN || .. .. | ||.| || . || || || | PEVIIGCKYDYRIDMWSLGCILAELWTGNVLFQNDN |
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| Kinase | 84561.m00139.AA | CLK | 235-278 | 35 | 4e-05 | 10.54 | In-house | 224-268 (350) | Show / Hide |
Range on Protein: 235-278 Range on HMM: 224-268/350 Sequence Identity: 35% (16 aa) WSYEIDIWQLGILFVELITGRKLFTHNNRLLHYALIEKLGG-QFP ||. |.| | .|| || || .. . | |..|.. | ..| WSQPCDVWSIGCILFELYTGFTLFQTHDNREHLAMMERIMGMPIP |
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| Kinase | 84561.m00139.AA | CDKL | 321-353 | 39 | 0.000154 | 11.44 | In-house | 254-286 (286) | Show / Hide |
Range on Protein: 321-353 Range on HMM: 254-286/286 Sequence Identity: 39% (13 aa) IHNDKALSFAQATLCTDPSRRLLPLQLINHPFI ..| |||.|... | ||..|. || .||. KSNKKALDFMKKCLHMDPDERMTCEQLMHHPYF |
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| Kinase | 84561.m00139.AA | DYRK2 | 226-258 | 39 | 0.000258 | 9.57 | In-house | 170-202 (318) | Show / Hide |
Range on Protein: 226-258 Range on HMM: 170-202/318 Sequence Identity: 39% (13 aa) SPEQLLSTRWSYEIDIWQLGILFVELITGRKLF .|| | .. . .||.| .| .|| || || APEVILGGKYGMAIDMWSFGCIMAELYTGYPLF |
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| Kinase | 84561.m00139.AA | DYRK2 | 337-353 | 52 | 0.001297 | 7.25 | In-house | 302-318 (318) | Show / Hide |
Range on Protein: 337-353 Range on HMM: 302-318/318 Sequence Identity: 52% (9 aa) DPSRRLLPLQLINHPFI ||| |. | | .||.| DPSERMTPSQALKHPWI |
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| Kinase | 84561.m00139.AA | CDKL | 226-258 | 35 | 0.001303 | 8.22 | In-house | 167-200 (286) | Show / Hide |
Range on Protein: 226-258 Range on HMM: 167-200/286 Sequence Identity: 35% (12 aa) SPEQLLS-TRWSYEIDIWQLGILFVELITGRKLF .|| |. | . ..||| .| .. |.|.| |. APELLVGDTQYGKPVDIWAIGCVMAEMIDGQPLW |
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| Kinase | 84561.m00139.AA | DYRK1 | 337-353 | 35 | 0.016106 | 4.09 | In-house | 305-321 (321) | Show / Hide |
Range on Protein: 337-353 Range on HMM: 305-321/321 Sequence Identity: 35% (6 aa) DPSRRLLPLQLINHPFI || .|. |.. . |.|. DPKQRITPYYALQHSFF |
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| Kinase | 84561.m00139.AA | DYRK2 | 143-168 | 34 | 0.05936 | 1.76 | In-house | 99-124 (318) | Show / Hide |
Range on Protein: 143-168 Range on HMM: 99-124/318 Sequence Identity: 34% (9 aa) FSLSTIRVFMWHLIHALELLHECKLI |||. .| | ....|..||. ..| FSLQLVRRFAHSILQCLRFLHKNNII |
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| Kinase | 84561.m00139.AA | CLK | 143-168 | 30 | 0.096107 | 0.19 | In-house | 111-136 (350) | Show / Hide |
Range on Protein: 143-168 Range on HMM: 111-136/350 Sequence Identity: 30% (8 aa) FSLSTIRVFMWHLIHALELLHECKLI . ...||.. . |..|.. ||. ||. YPIDHIRHMAYQLCEAVKFLHDMKLT |
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