Gene 90434.m00231 (T.vaginalis)

90434.m00231

Species: T.vaginalis
Alias: TvagK0079, 90434.m00231
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
90434.m00231.AA Protein None 314 None Fasta, JSON
90434.m00231.kin_dom Protein Kinase Domain None 196 None Fasta, JSON

Protein domain

Protein domains of 90434.m00231.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 90434.m00231.AA AMPK 1-198 46 1.5e-89 265.99 In-house 55-254 (254) Show / Hide 
Range on Protein: 1-198
Range on HMM: 55-254/254
Sequence Identity: 46% (93 aa)

MVSHPFIAQLFEII-ENEHYYFVVMEFVQNGTLLTYINERCQLKEQEAANIFAQMILVLKYLQDDCNVCHRDIKAENILMDTNYNICVIDFGLSNISPEN
.. || | ||.|.| | .   |.|||.|..| |  ||  .  |.|.||.  |.|.|  . |.  . .. ||| | ||.|.| |.|| . ||||||.  ..
LFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQEREACRFFQQIISGVEYC-HRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDG

-LMNTQCGSPAYASPEMILGQQYT-FSSDIWSCGCVLFAMVCGKLPFYDENISRLAQKIVYTEPQYPSTLSPMCTDLLKRILTKKPEERITINEIMNHDW
 .  | |||| ||.|||| |. |     |||||| .|.||.||.||| |||.. | .||.  |.. |. ||| . ||.|..|.. |..||||..|.||.|
EFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPFDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPW

V
 
F
Kinase 90434.m00231.AA CAMKL 1-198 35 4.7e-88 281.1 In-house 68-297 (297) Show / Hide 
Range on Protein: 1-198
Range on HMM: 68-297/297
Sequence Identity: 35% (83 aa)

MVS---HPFIAQLFEIIENEHY------YFVVMEFVQNGT--LLTYI--NERCQ--LKEQEAANIFAQMILVLKYLQDDCNVCHRDIKAENILMDTNY--
|..   || | .|.|.||.. .      .. ||| ...|   |. ||  ....   ..| ||  .| |..  ..|. . . ..|||||.|||| | |   
MLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHG-IVHRDIKPENILLDENGNN

NICVIDFGLSNI-SP-----ENLMNTQCGSPAYASPEMILG--QQYT-FSSDIWSCGCVLFAMVCGKLPFYDENIS---------RLAQKIVYTEPQYPS
|| .||||.||.  |     .....|.||||.|..||...|  ..|  .  |||||| .|.|||||.||| |....         .. ...  ..|  ..
NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWY

TLSPMCTDLLKRILTKKPEERITINEIMNHDWV
 .|  | ||....|...||.|.|| .|||| |.
HVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 90434.m00231.AA CAMK 1-198 23 5.2e-84 270.48 In-house 94-425 (425) Show / Hide 
Range on Protein: 1-198
Range on HMM: 94-425/425
Sequence Identity: 23% (79 aa)

MVSHPFIAQLFEIIENEHY-------------------YFVVM---EFVQNG----TLLTYINERCQ---------------LKEQEAANIFAQMILVLK
...|| | .|.|..|..||                   .. ||   |....|     |. || |. .               ..|.||. .| |..  ..
KLDHPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVH

YLQDDCNVCHRDIKAENILMDTN-----------------YNICVIDFGLSNISPEN-------------------------LMNTQCGSPAYAS-PEMI
|. .   ..|||.| ||||.|.|                 .|| .||||..|. ...                         .|.|.||.|.|.. ||..
YCHSHN-IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVL

LGQQ--------------YTFSSDIWSCGCVLFAMVCGKLPFYDE-------------NISRLAQKIVYTEPQYPST-----------------------
.|..              |....|.||||..|..|.||..|||..             |...| .||   . ..|.                        
NGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH

-LSPMCTDLLKRILTKKPEERITINEIMNHDWV
 .|. | ||....|.. ||.|.|| ...|| |.
FVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 90434.m00231.AA MARK 1-198 40 5.4e-77 251.24 In-house 55-262 (262) Show / Hide 
Range on Protein: 1-198
Range on HMM: 55-262/262
Sequence Identity: 40% (85 aa)

MVSHPFIAQLFEIIE--NEHY-YFVVMEFVQNGTLLTYINER--CQLKEQEAANIFAQMILVLKYLQDDCNVCHRDIKAENILMDTNY--NICVIDFGLS
...|| | .||..||  .|    ...|| . .| |. || ..    |.| ||  || |..  ..|. .   ..|||||.||||.| |   ||  ||||.|
KLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGRLHEEEARRIFRQIVSAVNYCHSKN-IVHRDIKPENILIDENGNHNIKIIDFGFS

NIS-PENLMNTQCGSPAYASPEMILGQQYT-FSSDIWSCGCVLFAMVCGKLPFYDEN--ISRLAQKIVYTEPQYPSTLSPMCTDLLKRILTKKPEERITI
..  |... || ||.|.|..||..|.. |. .  ||||.| ||..||||..|| . .  .  | .||.  ....|. .|. | .|..|.||  ||||.||
ICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTI

NEIMNHDWV
 |||.| |.
EEIMKHPWM
Kinase 90434.m00231.AA AGC 3-198 22 1.4e-73 188.7 In-house 88-395 (395) Show / Hide 
Range on Protein: 3-198
Range on HMM: 88-395/395
Sequence Identity: 22% (69 aa)

SHPFIAQ-LFEIIENEHY--YFVVMEFVQ---------NG-TLLTYINE--RCQ-LKEQEAANIFAQ-------MILVLKYLQDDCNVCHRD-IKAENIL
.|||| . |.   ... .   . |||...          |  |.... .  ... . |..|  ..|.       ..| | || .  .. ||| .| ||||
HHPFIVKILHYSFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENIL

MDTNYNICVIDFGLSNISP----------------------------------------------------ENLMNTQCG--SPAYASPEMILGQQYTFS
.| . .|.  ||||. . .                                                    ... .| ||  .| | .||..    |...
LDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKA

SDIWS--CGCVLFAMVCGKLPFYDEN----------ISRLAQKIV------YTEPQYP----------STLSPMCTDLLKRILTKKPEERIT--------
 |.||   ||... |..|. |||..|             . |||         ....|          . .|| . ||.|. |.| ||.|..        
CDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGD

--INEIMNHDWV
  ..||.|| | 
KGAEEIKNHPWF
Kinase 90434.m00231.AA Pkinase 1-198 28 1.3e-69 242.35 Pfam 56-293 (293) Show / Hide 
Range on Protein: 1-198
Range on HMM: 56-293/293
Sequence Identity: 28% (68 aa)

MVSHPFIAQLFEIIENEHYYFVVMEFVQNG----TLLTYIN--ERCQL--KEQEAANIFAQMILVLKYLQDDCNVCHRDIKAENILMDTNYNI----CVI
...||.| .|... |.. .. .|||....|     | .||   ... .   |.|. ... |..  |.|. . ....|||.| ||||.| |..|    ...
RLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKIC

DFGLSN---ISPENLMNTQCGSPAYASPEMIL-GQQYTFSSDIWSCGCVLFAMVCGKLPFYDE------NISRLAQKIVYTEPQYPSTLS----------
||||.    . .   |.| ||.| |..|| |. || |. ..|.|||||.|. |.||..||...      .   . ..| .... ...  .          
DFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRH

-----------PMCTDLLKRILTKKPEERITINEIMNHDWV
           . | |..|..|.|.|..|.|. .|..|.|.
WHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 90434.m00231.AA Ciliate-E2-Unclassified 1-198 30 2.1e-65 223.61 In-house 77-352 (352) Show / Hide 
Range on Protein: 1-198
Range on HMM: 77-352/352
Sequence Identity: 30% (83 aa)

MVSHPFIAQLFEIIENEHYYFVVMEFVQNGTLLTYINER-----------------CQLKEQEAA-----NIFAQMILVLKYLQDDCNVCHRDIKAENIL
.  ||||  .|.. ... . . |||....|.|. ||..|                 ... ||.|.     ..||| .. |.||    |..||||| ||||
NHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENIL

MDTNY---NICVIDFGLSN-----------------ISPENLMNTQCGSPAYA----SPEMILGQQYT----FSSDIWSCGCVLFAMVCGKLPFYDENIS
.| |    .|..||||.|                  | ....|.|.||.| |     .||.. ||.|     ...||||.|..|..|. |..||||.|  
FDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCE

R----------------LAQKIVYTEPQYPS--------TLSPMCTDLLK----RILTKKPEERITINEIMNHDWV
                 | |.|   ..|.|.        ..|| . |...    ..| |.|..|||...|.|| | 
QHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 90434.m00231.AA Ciliate-E2 3-198 27 3.3e-65 222.79 In-house 90-365 (365) Show / Hide 
Range on Protein: 3-198
Range on HMM: 90-365/365
Sequence Identity: 27% (77 aa)

SHPFIAQLFEIIE--NEHYYFVVMEFVQNGTLLTYINERC-----------QLKEQEAANIFAQMIL---------------VLKYLQDDCNVCHRDIKA
.||.| ...|  .  ...... |||..| |.|. ||....           ...|.|...|..| .                 |.||    |..||||| 
NHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKP

ENILMDTNYNICVIDFGLS-NISPE--------------------------------NLMNTQCGSPAYASPEMILGQQ---------YTFSSDIWSCGC
||||.     |..|||||| .....                                |. ||.||.| | .||.. |..         |....||||.|.
ENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGV

VLFAMVCGKLPFYDENISRLAQKIVYTEPQY-------------PSTLSPMCTDLLKR----ILTKKPEERIT-INEIMNHDWV
.|. |..||.||    .  . .|| . .|..             .  .|. | ||.|.    .| |.||.||| ...|.|| | 
ILYEMLFGKPPF---QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 90434.m00231.AA QIK 1-198 35 1.7e-62 213.94 In-house 54-272 (272) Show / Hide 
Range on Protein: 1-198
Range on HMM: 54-272/272
Sequence Identity: 35% (77 aa)

MVSHPFIAQLFEIIENEHYYFVVMEFVQNGTLLTYINERCQ--------------------LKEQEAANIFAQMILVLKYLQDDCNVCHRDIKAENILMD
| .||.|  |....| . . ..|.|. .|| .  |...  .                    ..|.||. .| |...  .|. .  |. |||.||||||.|
MLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKMVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKR-NIVHRDLKAENILLD

TNYNICVIDFGLSNIS-PENLMNTQCGSPAYASPEMILGQQYT-FSSDIWSCGCVLFAMVCGKLPFYDENISRLAQKIVYTEPQYPSTLSPMCTDLLKRI
 | || ..|||.|| . .. |..| ||||.|| ||| .|..|.   .|||| | ||...|||.|||  ...  | |...    . |  .|  | .| .. 
NNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHM

LTKKPEERITINEIMNHDWV
|.  || |.||. |..| | 
LVVDPEHRYTIMQICQHRWM
Kinase 90434.m00231.AA GIN4 1-198 38 7.6e-60 189.66 In-house 90-293 (293) Show / Hide 
Range on Protein: 1-198
Range on HMM: 90-293/293
Sequence Identity: 38% (79 aa)

MVSHPFIAQLFEIIENEHYYFVVMEFVQNGTLLTYINERCQLKEQEAANIFAQMILVLKYLQDDCNVCHRDIKAENILMDTNYN-ICVIDFGLSNISPEN
..||| . .|... |..   ..|.|... | |  |. .. .| |.|| ..| |.|  . |     |.||||.| ||.|.|  || | . |||.  .  .|
LISHPNVMRLYDVWETNNDLYLVLEYAEKGELFNYLVDHGPLPEREAIHYFRQIIIGVSYCH-AFNICHRDLKPENLLLDHKYNRIKIADFGMAALETDN

-LMNTQCGSPAYASPEMILGQQYT-FSSDIWSCGCVLFAMVCGKLPFYDE--NISRLAQKIVYTEPQYPST--LSPMCTDLLKRILTKKPEERITINEIM
 |..| |||| ||.||.. |  |  |.||.|||| .|||.. |.||| .|  || .|  |.   . . ||   .|    ||...||.  || ||.. .|.
KLLETSCGSPHYAAPEIVMGIPYHGFASDVWSCGVILFALLTGHLPFDEEDGNIRKLLLKVQKGKYEMPSDDEISREAQDLIRKILVVDPEKRIKTRDIL

NHDWV
 |  .
KHPLI
Kinase 90434.m00231.AA TSSK 1-198 36 8.9e-60 194.86 In-house 71-289 (289) Show / Hide 
Range on Protein: 1-198
Range on HMM: 71-289/289
Sequence Identity: 36% (80 aa)

M-VSHPFIAQLFEIIENEH-YYFVVMEFVQNGTLLTYINER-----CQ-LKEQEAANIFAQMILVLKYLQDDCNVCHRDIKAENILMDTNYNICVIDFGL
. . ||.| |..|..|...   . |||. ..|.|| ||..|     |  |.|..|   | ||.  .||.. ..|| |||.| ||||.|.. ||  .||| 
KTLKHPNIIQFYEMFETCQGKIYMVMEYAEHGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCH-SHNVVHRDLKCENILLDKHWNIKLTDFGF

SN-ISPEN------LMNTQCGSPAYASPEMILGQQY-TFSSDIWSCGCVLFAMVCGKLPFYD--ENISRLAQKIVYTEPQYP----STLSPMCTDLLKRI
..  ..        |  | ||| |||.|| ..|  |  . .|.||.| .|..||||..|| |   || .. . .   ....|     ..|. | ||....
ARYWPRDDPGRCCHLSKTFCGSYAYAAPEILRGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHM

LTKKPEERITINEIMNHDWV
|.  | .|..||||..| |.
LQPHPCNRPHINEICHHCWM
Kinase 90434.m00231.AA S_TKc 1-198 25 5.9e-52 179.84 SMART 1-231 (231) Show / Hide 
Range on Protein: 1-198
Range on HMM: 1-231/231
Sequence Identity: 25% (65 aa)

MV-------------------------------------------SHPFIAQLFEIIENEHYYFVVMEFVQN--GTLLTYINERCQ------LKEQEAAN
                                              ||.| .|...... .....|||.. .  |.|..|| .|        . | .|. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARF

IFAQMILVLKYLQDDCNVCHRDIKAENILMDTNYNICVIDFGLSNISPENLMNTQCGSPAYASPEMILGQQYTF-SSDIWSCGCVLFAMVCGKLPFYDEN
...|... |.|. .  ...|||.| ||||.|.  .| ..||||. .      .|.||.| | .||..   .|.. ..|.|||||.|. |.||. ||.  .
YMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--Q

ISRLAQKIVYTEPQYPSTLSPMCTDLLKRILTKKPEERITINEIMN-------HDWV
. .. .||.          || . |.....|.| ||.|.|. |...       | |.
MQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 90434.m00231.AA TyrKc 2-198 18 3.1e-09 -73.28 SMART 1-280 (280) Show / Hide 
Range on Protein: 2-198
Range on HMM: 1-280/280
Sequence Identity: 18% (52 aa)

V------------------------------------------------SHPFIAQLFEIIENE-------HYYFVVMEFVQNGTLLTYI-NERCQLKEQ
.                                                .|| | .|. ..  .       . ...|||.. .| |. |. . | .|. .
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

EAANIFAQMILVLKYLQDDCNVCHRDIKAENILMDTNYNICVIDFGLSNISPEN--------LMNTQC--GSP-----AYASPEMILGQQYTFSSDIWSC
.  ..  |      || .  |. |||. | |.| . |. . . |||||    .            ..   |.         .|| |    .|. ||.|| 
DLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSF

GCVLF-AMVCGKLPFYD-----ENISRLAQKIV--YTEPQYPS-------TLSPMCTDLLKRILTKKPEERITINEIMNHDWV
| ...  .  |. | ..      . ... ...   |  || |.       . ..   .. |.    .||.| | .||  |.  
GVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF