Gene 82588.m00113 (T.vaginalis)
82588.m00113
Species: T.vaginalis
Alias: 82588.m00113, TvagK0155
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
---|---|---|---|---|---|
82588.m00113.AA | Protein | None | 212 | None | Fasta, JSON |
82588.m00113.kin_dom | Protein Kinase Domain | None | 148 | None | Fasta, JSON |
Protein domains of 82588.m00113.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 82588.m00113.AA | Pkinase | 37-173 | 26 | 1.2e-31 | 113.04 | Pfam | 124-293 (293) | Show / Hide |
Range on Protein: 37-173 Range on HMM: 124-293/293 Sequence Identity: 26% (46 aa) CHEFGIRHGDVKPSNFLIDKYGRV----KICDFGFSQK--LNRDENNTNFSGTFIYESPEIIRQEPFDGFAADIWALGVSYFILITGQCPWNLY------ ||. || | |.||.|.|||. | . ||||||.. . . ... .| | || | .||.|| . .| ..|.|..|. .....|. |. CHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNH SKDAMIKSIQNAIFDEFQIND---------------------LLLRRIVSLCLQIDPTKRPSAEDLVNM--L ....||. | ..... .. .. ... ||. ||.|||.||.... . DQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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Kinase | 82588.m00113.AA | Ciliate-E2 | 34-171 | 21 | 6e-30 | 99.99 | In-house | 173-361 (365) | Show / Hide |
Range on Protein: 34-171 Range on HMM: 173-361/365 Sequence Identity: 21% (43 aa) LQSCHEFG-IRHGDVKPSNFLIDKYGRVKICDFGFSQKLNRDENNTN--------------------------------FSGTFIYESPEIIRQEPFDG- |...|. . | | | ||.| |. .||.|||.|.|.. |..|. . || | .|||.. .. |. LEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQ -------FAADIWALGVSYFILITGQCPWNLYSKDAMIKSIQNAIFD------------------EFQINDLLLRRIVSL----CLQIDPTKRPS-AEDL ...|||.||| .....|. |. .. |.. .| ... .. . . .|| || ||.. .|.. QKQKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQI VN | LN |
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Kinase | 82588.m00113.AA | CAMK | 37-171 | 19 | 7.7e-30 | 92.76 | In-house | 195-421 (425) | Show / Hide |
Range on Protein: 37-171 Range on HMM: 195-421/425 Sequence Identity: 19% (45 aa) CHEFGIRHGDVKPSNFLIDKY-----------------GRVKICDFGFSQKLNRDENNTN------------------------FSGTFIYES-PEIIRQ ||. .| | | || | |.|. . .||.||||..|....|||.. | || | . ||.... CHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNG -------------EPFDGFAADIWALGVSYFILITGQCPWNLY-------------SKDAMIKSIQNAIFD-EFQINDL--------------------- .| .|...|.|..|| .|. .| |.. . . . |... .| . . KGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFV --LLRRIVSLCLQIDPTKRPSAEDLVN . .. .|| ||.||...|. | SQECKDLIRKMLQVDPEKRMTIEQCLN |
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Kinase | 82588.m00113.AA | MARK | 37-171 | 32 | 1.1e-29 | 94.35 | In-house | 120-258 (262) | Show / Hide |
Range on Protein: 37-171 Range on HMM: 120-258/262 Sequence Identity: 32% (46 aa) CHEFGIRHGDVKPSNFLIDKYG--RVKICDFGFSQKLNRDENNTNFSGTFIYESPEIIRQEPFDGFAADIWALGVSYFILITGQCPWNLYS--KDAMIKS ||. .| | | || | |||. | .||.||||| . . .. . | || | .|||. ..| ||...|||.||| .....|. |. .. . | CHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKK IQNAIFDEFQINDL--LLRRIVSLCLQIDPTKRPSAEDLVN |.. .| . . . .| .... |...| .||..|.... ILRGKYD-IPCH-VSKECRNLIQRLLTVNPEERPTIEEIMK |
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Kinase | 82588.m00113.AA | Ciliate-E2-Unclassified | 1-171 | 19 | 2.2e-29 | 99.12 | In-house | 100-348 (352) | Show / Hide |
Range on Protein: 1-171 Range on HMM: 100-348/352 Sequence Identity: 19% (48 aa) MEYCPSSIDKIFLE-RWV-----------------LTNEELY-----RYAIGMAQSLQSCHEFG-IRHGDVKPSNFLIDKYG---RVKICDFGFSQKLN- ||||. . ... |. .| .. .|. | |...|. . | | | ||.| |.|. | ..||.|||.| |.. MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ ---------------RDENNTNFSGTFIYE----SPEIIRQEPFDG---FAADIWALGVSYFILITGQCPWNLYSKDA----------------MIKSIQ .... . |.|| .| .||..... |. ...|||.||| . ...|..| . .... ... |. NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK NAIFDEF--------QINDLLLRRIVS----LCLQIDPTKRPSAEDLVN . ... . .. . ... .|. .| ||...|.. | QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILN |
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Kinase | 82588.m00113.AA | AGC | 34-169 | 18 | 1.1e-28 | 69.99 | In-house | 166-389 (395) | Show / Hide |
Range on Protein: 34-169 Range on HMM: 166-389/395 Sequence Identity: 18% (43 aa) LQSCHE-FGIRHGD-VKPSNFLIDKYGRVKICDFGFSQKLNRDE---------------------------------------------------NNTNF |.. |. || | | .|| | |.|. | .|..|||.. ....|. .. | LEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTF SG--TFIYESPEIIRQEPFDGFAADIWA--LGVSYFILITGQCPWNL----------YSKDAMIKSIQNAI---FDEFQIN-------------DLLLRR | | | .|||. |.|.|.|. ||. . ..||. | . .... | ..|.| . ... ... . .. CGPCTPEYMAPEIL-----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKD IVSLCLQIDPTKRPS----------AEDL ... .|. ||.||. ||.. LIKKLLCKDPEKRLGCGGNDFGDKGAEEI |
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Kinase | 82588.m00113.AA | CAMKL | 37-171 | 27 | 3e-28 | 87.12 | In-house | 143-293 (297) | Show / Hide |
Range on Protein: 37-171 Range on HMM: 143-293/297 Sequence Identity: 27% (43 aa) CHEFGIRHGDVKPSNFLIDKYG--RVKICDFGFSQKLNR-----DENNTNFSGTFIYESPEIIRQ--EPFDGFAADIWALGVSYFILITGQCPWN----- ||. || | | || | |.|. | .||.||||| . . .. . | |. | .|||. .|.||...|||..|| . ...|. |.. CHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYN -----LYSKDAMIKSIQNAIFDEFQINDLLLRRIVSLCLQIDPTKRPSAEDLVN . . .. .. .. . . .|.. . || .|.|||......| KQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMN |
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Kinase | 82588.m00113.AA | STE | 1-169 | 21 | 1.4e-26 | 90.95 | In-house | 116-351 (359) | Show / Hide |
Range on Protein: 1-169 Range on HMM: 116-351/359 Sequence Identity: 21% (52 aa) MEYCP-SSIDKIFLER--------------WVLTNEELYRYAIGMAQS-LQSCHEFGIRHGDVKPSNFLIDKYGRVKICDFGFSQKLNR----------- |||.. |.|.| .. ... ... ... . |. |. .| | |.||.| |. ||.||||.. .|. MEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNII ------DENNTNFSGTFIYESPEIIRQEPFD-----GFAADIWALGVSYFILITGQCPW-NLYSKDAMIKSIQN-AIF-----------DEFQIND---- ..... | || . .||.|.|. . .. .||| || ..||. || ... || ..| ... . .. | DCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQ ------------------LLLRRIVSLCLQIDPTKRPSAEDL .. ...|||.|| |||.|..| NEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQL |
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Kinase | 82588.m00113.AA | CAMKK | 29-120 | 27 | 5.7e-24 | 72.59 | In-house | 184-325 (396) | Show / Hide |
Range on Protein: 29-120 Range on HMM: 184-325/396 Sequence Identity: 27% (39 aa) GMAQSLQSCH-EFG-------------------IRHGDVKPSNFLIDKYG---RVKICDFGFSQKL-NRDENNTN-----------FSGTFIYESPEIIR .... |. .| . . | | | ||.| |||. | .|||.||| |... |... | || . || .. DCIKGLEYLHNYQKACSYIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFGVSHIFEGQDQTLSNCESCFQRELNKTAGTPAFMAPELCS QEP---------------FDGFAADIWALGVSYFILITGQCP | ..|.|||||||||. .....|.|| KENQKENYNGYKYRFRFIYCGKAADIWALGVTLYCFVFGKCP |
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Kinase | 82588.m00113.AA | TKL | 1-173 | 17 | 1.7e-22 | 77.84 | In-house | 117-364 (364) | Show / Hide |
Range on Protein: 1-173 Range on HMM: 117-364/364 Sequence Identity: 17% (45 aa) MEYCPSSI-DKIFLERWVLTNEELYRYAIGMAQSLQSCHEFG--------IRHGDVKPSNFLIDKYGR--------------VKICDFGFSQKLNRDEN- ||||| ... . . | |...|. .. | . | | | |..| |.|. .. .||||||.|. .....| MEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNM -------------------NTNFSGTFIYESPEIIRQEPFDGFAA---------------DIWALGVSYFILITGQCPW--NLYS------------KDA . . ||. . .||..|..... .. |... |. . ..|.. |. . |. . . NDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMV MIKSIQNAIFDEFQ------INDLL---LRRIVSLCLQIDPTKRPSAEDLVNML |. . | .. | .. .... | . ||.||||..... | CDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL |
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Kinase | 82588.m00113.AA | ULK | 38-163 | 23 | 1.6e-20 | 69.56 | In-house | 143-312 (324) | Show / Hide |
Range on Protein: 38-163 Range on HMM: 143-312/324 Sequence Identity: 23% (40 aa) HEFGIRHGDVKPSNFLIDKY------------GRVKICDFGFSQKLNRDENNTNFS----------GTFIYESPEIIR----QEPFDGFAADIWALGVSY |. .| | | ||.| || . |..||.||||..... .. . . || .| .|.|. |.|.. . .||| ||. . HKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIF FILITGQCP---WNLYSKDA-MIKSIQN------AIFD---EFQIND------LLLRRIVSLCLQIDPTKR . ...|..| | .. . ..| |.| | . .|.... .. . . .||.|...| YEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDR |
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Kinase | 82588.m00113.AA | S_TKc | 1-173 | 18 | 2.2e-13 | 19.26 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 1-173 Range on HMM: 1-231/231 Sequence Identity: 18% (48 aa) M-----------------------------------------------------------------EYCPS---SIDKIFLERWV------LTNEELYRY |||. . .. .| .. . .| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFY AIGMAQSLQSCHEFGIRHGDVKPSNFLIDKYGRVKICDFGFSQKLNRDENNTNFSGTFIYESPEIIRQEPFDGFAADIWALGVSYFILITGQCPWNLYSK . ... |. ||. || | |.||.| |.|. ..||||||.. .| | | || | .||.. .......|.|..|. .....|. |. MYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QM DAMIKSIQNAIFDEFQINDLLLRRIVSLCLQIDPTKRPSAEDLVN---------ML ..|.| | . .. ... ||| ||.|||.| .. . . QMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |