Gene 89234.m00107 (T.vaginalis)
89234.m00107
Species: T.vaginalis
Alias: 89234.m00107, TvagK0874
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| 89234.m00107.AA | Protein | None | 969 | None | Fasta, JSON |
| 89234.m00107.kin_dom | Protein Kinase Domain | None | 170 | None | Fasta, JSON |
Protein domains of 89234.m00107.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 89234.m00107.AA | VPS15 | 86-296 | 26 | 2.3e-23 | 77.75 | In-house | 61-296 (296) | Show / Hide |
Range on Protein: 86-296 Range on HMM: 61-296/296 Sequence Identity: 26% (64 aa) IIDYSNIIINDRYAFLIRPKKQYTLPQRLEEYPRLEEIEKRWVVFQIYSAISSLHSIN-LVHGALNPDNIFVDWDISTTVG------DLAPFKPTQIRAD . |. .| |..| ..| .| |. | |..|||.|. ||. |.. .| . .||.. . || | |.. | |.|||. . | CCPYQKVIETDKAAYMMRQYVKHNLYDRISTRPFLQMIEKKWIAFQTLCALEQCHKQGNVCHGDIKSENILV------TSWNWCYLTDFACFKPCYLPED KPNVYHHYFSTSTRNGCYLAPEQII----TEDNVLD----------------PLFFSNLKISADLFSIGCIVYYLYT-G-THLFNFSTLIQFKEG--KFN | . .| || |. ||.||| . . ... | | |. . | || ||.. |.. | . .|..| | .. | .| NPADFTFFFDTSRRRTCYIAPERFVSNTEQDQDSNNGNMRDIHTDSIDRQQNPWLFGELTPAMDIFSAGCVIAELFCEGDQPPFDYSQLCKYRSGEYHPN LDAKLQALPD-KIRNFARTLLDID-PNSRQEVNTSLSKYFPPCF .. .. | .||| ....| | | . |.|. . | REQIMEKIQDEHIRNLCHHMIQKDNPMKRMSCEEYLNKW--RGF |
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| S_TKc | 89234.m00107.AA | S_TKc | 23-292 | 15 | 4.5e-09 | -43.81 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 23-292
Range on HMM: 1-231/231
Sequence Identity: 15% (46 aa)
ITVKNSIDSGTFLLTLDCVNQY-NEPLIVKAYEYTESLEKGNLGVDNSRKYFNHLTDKIQATQCIIDYSNIIINDRYAFLIRPKKQY---TLPQRLEEYP
.. . | .|.| |.. .. .| .. |. . | |. . .. . . ... .| .......
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------EHIRREIQILKK---HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG
R------LEEIEKRWVVFQIYSAISSLHSINLVHGALNPDNIFV-------DWDISTTVGDLAPFKPTQIRADKPNVYHHYFSTSTRNGCYLAPEQIITE
| . | . | .. || .|. .|| . .| | |.||.. | ... . ... | |.||| .
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQL-------------------TTFCGTP----WYMAPEVL---
DNVLDPLFFSNLKI-SADLFSIGCIVYYLYTGTHLFNFSTLIQFKEGKFNLDAKLQALPDKIRNFARTLLDIDPNSRQEVNTSLS--------KYF
..| |.|||.| ...| .| || . .. ..| | .|. ||. | . | .|
----------GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
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| Kinase | 89234.m00107.AA | Ciliate-E2 | 220-281 | 17 | 4.1e-08 | 23.94 | In-house | 276-352 (365) | Show / Hide |
Range on Protein: 220-281 Range on HMM: 276-352/365 Sequence Identity: 17% (14 aa) SADLFSIGCIVYYLYTGTHLFNFSTLIQFKEGKFNLDAKL---------------QALPDKIRNFART----LLDIDPNSR ..|..|.|.| |.. .| . | ..| |..|.... . . .... .. . .|. ||. | KCDIWSLGVILYEMLFGKPPF----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKR |
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| Kinase | 89234.m00107.AA | ERK7 | 120-157 | 39 | 4.3e-07 | 19.97 | In-house | 97-134 (292) | Show / Hide |
Range on Protein: 120-157 Range on HMM: 97-134/292 Sequence Identity: 39% (15 aa) LEEIEKRWVVFQIYSAISSLHSINLVHGALNPDNIFVD |..| |. ...|. || .|| |..| | | || .| LKDIHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLD |
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| Kinase | 89234.m00107.AA | TBCK | 130-157 | 39 | 1.7e-05 | 15.57 | In-house | 87-114 (346) | Show / Hide |
Range on Protein: 130-157 Range on HMM: 87-114/346 Sequence Identity: 39% (11 aa) FQIYSAISSLHSINLVHGALNPDNIFVD .|| ...| .|. ..||..| |.|| | YQILCGLSYMHKHHIVHRFLHPHNIYLD |
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| Kinase | 89234.m00107.AA | Ciliate-E6 | 131-157 | 40 | 3.1e-05 | 13.02 | In-house | 61-87 (154) | Show / Hide |
Range on Protein: 131-157 Range on HMM: 61-87/154 Sequence Identity: 40% (11 aa) QIYSAISSLHSINLVHGALNPDNIFVD |. .|.. ||| |.|.. . . |||.| QLFHAVEYLHSKNYVLQNITLKNIFLD |
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| Kinase | 89234.m00107.AA | IRE | 222-240 | 55 | 6.8e-05 | 12.43 | In-house | 214-233 (292) | Show / Hide |
Range on Protein: 222-240 Range on HMM: 214-233/292 Sequence Identity: 55% (11 aa) DLFSIGCIVYYLYT-GTHLF | || ||..||..| |.| | DIFSMGCVFYYVMTNGQHPF |
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| Kinase | 89234.m00107.AA | Ciliate-E2a | 222-281 | 24 | 0.0001 | 9.86 | In-house | 198-263 (275) | Show / Hide |
Range on Protein: 222-281 Range on HMM: 198-263/275 Sequence Identity: 24% (16 aa) DLFSIGCIVYYLYTGTHLFNF----STLIQFKEGKFNLDAKL--QALPDKIRNFARTLLDIDPNSR |..|.|.| | | .|. .|. .|.| |. |.... . . ... .. . .|. ||. | DMWSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKR |
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| Kinase | 89234.m00107.AA | Ciliate-D1 | 222-240 | 42 | 0.000101 | 16.51 | In-house | 1-19 (19) | Show / Hide |
Range on Protein: 222-240 Range on HMM: 1-19/19 Sequence Identity: 42% (8 aa) DLFSIGCIVYYLYTGTHLF |..|.||| |.. .| . | DIWSFGCILYEMLFGQPPF |
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| Kinase | 89234.m00107.AA | Ciliate-E2-Unclassified | 219-281 | 15 | 0.000312 | 10.61 | In-house | 249-340 (352) | Show / Hide |
Range on Protein: 219-281 Range on HMM: 249-340/352 Sequence Identity: 15% (14 aa) ISADLFSIGCIVYYLYTGTHLFNFST-------------------LIQFK-EGKFNLDAKLQ-----ALPDKIRNFAR----TLLDIDPNSR ...| .| |.| |.. .|.. |. . |.| . ..... . . .... .| . .|. .||.| YKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKR |
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| Kinase | 89234.m00107.AA | PLK1 | 120-166 | 27 | 0.000371 | 9.27 | In-house | 96-142 (253) | Show / Hide |
Range on Protein: 120-166 Range on HMM: 96-142/253 Sequence Identity: 27% (13 aa) LEEIEKRWVVFQIYSAISSLHSINLVHGALNPDNIFVDWDISTTVGD . | | |. . || .. || ...| | |.|.. .. .|| ITEPECRYYMYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHLQVKIGD |
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| Kinase | 89234.m00107.AA | PLK1 | 222-293 | 28 | 0.000553 | 8.69 | In-house | 181-253 (253) | Show / Hide |
Range on Protein: 222-293 Range on HMM: 181-253/253 Sequence Identity: 28% (21 aa) DLFSIGCIVYYLYTGTHLFNFSTLIQ-FKEGKFNLDAKLQALPDKIRNFARTLLDIDPNSRQEVNTSLSKYFP |..|||||.| | | | ..| . .. | | . . ... | .|| ||..| ... |.. | DIWSIGCIMYILLFGQPPFETKCLKETYSRIKKNEYRIPSHISQPAAQLIRKMLDPDPTRRPTIEQVLNDEFF |
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| Kinase | 89234.m00107.AA | Ciliate-E2-Unclassified | 106-157 | 17 | 0.003651 | 6.85 | In-house | 104-178 (352) | Show / Hide |
Range on Protein: 106-157 Range on HMM: 104-178/352 Sequence Identity: 17% (13 aa) KQYTLPQRLEEYPR-----------------LEEIEKR-----WVVFQIYSAISSLHSIN-LVHGALNPDNIFVD .. .| | ..... ..| . . || .....||. | .| . |.||..| EGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFD |
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| Kinase | 89234.m00107.AA | IRE | 131-157 | 40 | 0.106987 | 1.16 | In-house | 124-150 (292) | Show / Hide |
Range on Protein: 131-157 Range on HMM: 124-150/292 Sequence Identity: 40% (11 aa) QIYSAISSLHSINLVHGALNPDNIFVD |. . .. ||| | || |.| || .. QCMNGLQHLHSQNIVHRDLKPHNILIH |
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| Kinase | 89234.m00107.AA | Ciliate-E2 | 112-156 | 23 | 0.142127 | 1.15 | In-house | 131-194 (365) | Show / Hide |
Range on Protein: 112-156 Range on HMM: 131-194/365 Sequence Identity: 23% (15 aa) QRLEEYP---RLEEIEKRWVVFQIYS---------------AISSLHSIN-LVHGALNPDNIFV .|..| . .. | | . . || . |. .||| | .| . |.||.. KRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF |
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