Gene 94687.m00137 (T.vaginalis)

94687.m00137

Species: T.vaginalis
Alias: 94687.m00137, TvagK0982
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
94687.m00137.AA Protein None 404 None Fasta, JSON
94687.m00137.kin_dom Protein Kinase Domain None 208 None Fasta, JSON

Protein domain

Protein domains of 94687.m00137.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 94687.m00137.AA Ciliate-E2 72-264 18 4.5e-29 96.93 In-house 91-365 (365) Show / Hide 
Range on Protein: 72-264
Range on HMM: 91-365/365
Sequence Identity: 18% (52 aa)

HPFIARYIQHFE--DDKYVYIILEPMKGGPFKELLEAKTRW-----------NETQSRSIFIQLF---------------MAIEYMQTAMAMVHGNICLD
||.| ... .|.  ||...|...|  .||  ..... .  .           .| . . |. |..                |.||.      .| .| ..
HPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPE

VFMVDENNYIRLVDFW--GIQPINNCSNSQTLVFNK------------------------------IPFQTPEYLN-TGI--------ITPSADIWALGV
  ..     | ..||    .. ..|. ... .. .|                               ... || ||  ..         . ..|||.|||
NILF-----IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGV

FLYFICVGSSPFSTDTIESVTKMDILYPSF------------------LSGPITDLLKK----LISLSPAHRLN-FRAIKEHPWF
 ||. . |  ||    ..   . .| .|..                  .|    ||.||    ..   |  |.. .  |..||||
ILYEMLFGKPPF----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 94687.m00137.AA AGC 183-264 21 1.2e-24 59.28 In-house 276-395 (395) Show / Hide 
Range on Protein: 183-264
Range on HMM: 276-395/395
Sequence Identity: 21% (27 aa)

PEYLNTGIITPSADIWA--LGVFLYFICVGSSPFST--------------DTIESVT------KMDILYP----------SFLSGPITDLLKKLISLSPA
|| |     ....|.|.  ||...|   .| .||.               .. ...       . .. .|          ...|    ||.|||.   |.
PEIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPE

HRLN----------FRAIKEHPWF
.||           .  ||.||||
KRLGCGGNDFGDKGAEEIKNHPWF
Kinase 94687.m00137.AA Ciliate-E2-Unclassified 42-264 18 4.8e-22 73.27 In-house 34-352 (352) Show / Hide 
Range on Protein: 42-264
Range on HMM: 34-352/352
Sequence Identity: 18% (60 aa)

SAKIYS-KQFLAKEHNQEYFENDIYCFK----------------TFYHPFIARYIQHFEDDKYVYIILEPMKGGPFKELLEAKTR---------------
...||. || . |. .    .. . . |                 ..|||| ... .|.|....||..| ..||  .. .. .                 
KIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQR

--WNETQSR-----SIFIQLFMAIEYMQTAMAMVHGNICLDVFMVDENN---YIRLVDFWGIQPINNCSNSQTLV---------FNKIPFQT--------
    | |..      .| |.  ..||.      .| .| ..  ..|.|.   ||.. ||  .  .....|..            ....  ..        
KIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQ

---PEYLNTGIITPS----ADIWALGVFLYFICVGSSPFS-TD-------------------TIESV----------------TKMDILYPSFLSGPITD
   ||.|       |    .|||.||| ||... |  ||. ..                    ..                   . .  .  |..    |
YTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFIN----D

LLKKLISLSPAHRLNFRAIKEHPWF
||.|..   |  |..|  |..||||
LLQKMLKKNPNKRITFEQILNHPWF
Kinase 94687.m00137.AA Aur 194-264 35 1.4e-19 47.81 In-house 181-257 (257) Show / Hide 
Range on Protein: 194-264
Range on HMM: 181-257/257
Sequence Identity: 35% (27 aa)

SADIWALGVFLYFICVGSSPFST-----DTIESVT-KMDILYPSFLSGPITDLLKKLISLSPAHRLNFRAIKEHPWF
. |||.||| .|  |.| .||        |.. .  |.|| .||..|    || .|.    | .|..   |..|||.
KVDIWCLGVLCYELCHGCPPFESNENHDETYDRIKNKVDIQFPSHISKEAKDLISKILQHDPKQRMTLDQIMNHPWI
Kinase 94687.m00137.AA CAMKL 193-264 27 1.7e-19 58.71 In-house 215-297 (297) Show / Hide 
Range on Protein: 193-264
Range on HMM: 215-297/297
Sequence Identity: 27% (23 aa)

PSADIWALGVFLYFICVGSSPFSTDT-------------IESVTKMDILYPSFLSGPITDLLKKLISLSPAHRLNFRAIKEHPWF
| .|||..|| ||.. .|  ||  ||             .. ..   .  ....| .  ||..|.    | .| .   |..|||.
PKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 94687.m00137.AA PLK1 38-264 21 1.8e-19 60.45 In-house 24-253 (253) Show / Hide 
Range on Protein: 38-264
Range on HMM: 24-253/253
Sequence Identity: 21% (50 aa)

NQEVSAKIYSKQFLAKEHNQEYFENDIYCFKTFYHPFIARYIQHFEDDKYVYIILEPMKGGPFKELLEAKTRWNETQSRSIFIQLFMAIEYMQTAMAMVH
.. . .|. .|..| |.| ..    .|   .   |. | .. ..|||...|||.||  .   . ||   .    |  .|   .|.  ...|..  . ..|
KEVFAGKVVPKSLLIKQHQRDKMTQEIQIHRQLHHRHIVKFHHFFEDKQNVYIVLELCRRRSLMELHKRRKAITEPECRYYMYQIVEGCQYLH-NNKIIH

GNICLDVFMVDENNYIRLVDFWGIQPINNCSNSQTLVFNKIPFQTPEYLNTGIITPSADIWALGVFLYFICVGSSPFST----DTIESVTKMDILYPSFL
  . |    ....  ... ||     ...    .        .  || ||    .   |||..|  .| . .|. || |    .|   . | .   || .
RDLKLGNLFLNDHLQVKIGDFGLATKCEYDGERKKTLCGTPNYIAPEVLNKKGHSFEVDIWSIGCIMYILLFGQPPFETKCLKETYSRIKKNEYRIPSHI

SGPITDLLKKLISLSPAHRLNFRAIKEHPWF
| |  .|..|..   | .| . ... .  .|
SQPAAQLIRKMLDPDPTRRPTIEQVLNDEFF
Kinase 94687.m00137.AA SAK 28-264 22 3.8e-19 61.61 In-house 14-254 (254) Show / Hide 
Range on Protein: 28-264
Range on HMM: 14-254/254
Sequence Identity: 22% (55 aa)

AIWNAHHTISNQEVSAKIYSKQFLAKEHNQEYFENDIYCFKTFYHPFIARYIQHFEDDKYVYIILEPMKGGPFKELLEAKTR-WNETQSRSIFIQLFMAI
... |.     |||  |.  |. . |    .   |..       || |    ..|||  |||..||  . | ..  .. . | . |.  |... |. . .
CVYRAKCIHTHQEVAIKMIDKKLMQKTGMVQRVRNEVEIHCQLKHPSILELYNYFEDNNYVYLVLEMCHNGEMHRYMKHRMRPFTEEEARHFMHQIVIGM

EYMQTAMAMVHGNICLDVFMVDENNYIRLVDFWGIQPINNCSNSQTLVFNKIP-FQTPEYLNTGIITPSADIWALGVFLYFICVGSSPFSTDTIES----
 |.  .  ..|  . |   ..  .  ... || |.    .  . . . .   | .  ||    .     .|.|.||  || . .|  || ||....    
LYLH-SHGIMHRDLTLSNILLTRDMHCKIADF-GLATQLKMPHEKHYTMCGTPNYISPEIATRTAHGLQSDVWSLGCMLYTLLIGRPPFDTDAVKNTLNK

VTKMDILYPSFLSGPITDLLKKLISLSPAHRLNFRAIKEHPWF
|   .   |..||    ||..|..   |. |.   ..  ||. 
VMMAEYIMPAHLSMEAQDLIHKMLRKNPHERITLSTVLCHPFM
Kinase 94687.m00137.AA Ciliate-E2b 194-264 26 4.8e-16 45.4 In-house 190-272 (272) Show / Hide 
Range on Protein: 194-264
Range on HMM: 190-272/272
Sequence Identity: 26% (22 aa)

SADIWALGVFLYFICVGSSPFSTDT------IESVTKM--DILYPSFLSGPIT--DLLKKLISLSPAHRL--NFRAIKEHPWF
..|||..|..||.. .|  |.  |        . ..|   .| .||...  .   .|  .. . .|  ||   . . | ||||
KVDIWSVGICLYEFMCGYVPWAEDVQDPYEIYQEIIKKYDEIQFPSYCKDKMADKKLMLQCLQKMPEVRLGGSYSWLKSHPWF
Kinase 94687.m00137.AA CAMK 191-264 20 9.6e-16 46.52 In-house 311-425 (425) Show / Hide 
Range on Protein: 191-264
Range on HMM: 311-425/425
Sequence Identity: 20% (23 aa)

ITPSADIWALGVFLYFICVGSSPFSTD-----------------TIESVTKMDIL-YPSFLSG-----------------------PITDLLKKLISLSP
..|..|.|..|| ||.  .| .||  |                 . | ..| .   .|...|.                          ||..|.    |
YGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDP

AHRLNFRAIKEHPWF
 .|..   ...|||.
EKRMTIEQCLNHPWM
S_TKc 94687.m00137.AA S_TKc 22-264 18 3.8e-15 45.19 SMART 1-231 (231) Show / Hide 
Range on Protein: 22-264
Range on HMM: 1-231/231
Sequence Identity: 18% (52 aa)

FINERY-------AIWNAHHTISNQEVSAKIYSKQFLAKEHNQEYFENDIYCFKTFYHPFIARYIQHFEDDKYVYIILEPMKG--GPFKELLEAKTR---
.   |          . ..|. ....|  || .          | ... | . |   ||.| ... .|.| ...|...| . |  |  ..... . |   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---WNETQSRSIFIQLFMAIEYMQTAMAMVHGNICLDVFMVDENNYIRLVDF---WGIQPINNCSNSQTLVFNKIPFQTPEY-----LNTGIITP-SADI
    .| . |... |.. |.||.      .|  .  .  ..||   | . ||     .               .    ||.|     |     .. ..|.
RFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL---------------TTFCGTPWYMAPEVL---GYGKCKCDW

WALGVFLYFICVGSSPFSTDTIESVTKMDILYPSFLSGPITDLLKKLISLSPAHRLNFRAIKE-------HPWF
|..|. ||  ..|  ||.    . ..   |.     | .  |...|.    |..|.    . .       ||||
WSCGCILYEMLCGYPPFP---QMQMMFKKIG-----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 94687.m00137.AA Pkinase 191-264 18 1.2e-11 42.3 Pfam 189-293 (293) Show / Hide 
Range on Protein: 191-264
Range on HMM: 189-293/293
Sequence Identity: 18% (19 aa)

ITPSADIWALGVFLYFICVGSSPFSTD----------TIESVTKMDILYPSFLS---------------------GPITDLLKKLISLSPAHRLNFRAIK
..|..|.|..|. ||  . |  ||. .           |. . . .. .... .                      .  |..|... . |. |.... |.
YGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQIL

EHPWF
.||||
QHPWF
Kinase 94687.m00137.AA RSK 192-264 28 4.3e-11 37.13 In-house 190-278 (278) Show / Hide 
Range on Protein: 192-264
Range on HMM: 190-278/278
Sequence Identity: 28% (25 aa)

TPSADIWALGVFLYFICVGSSPFST-------DTIESVTKMD--ILYP--SFLSGPITDLLKKLISLSPAHRLN-----FRAIKEHPWF
. ..|.| ||| .|   .| .||         .... . | .     |  ..|| .  ||..|.    |. ||.        ||.||||
DKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 94687.m00137.AA Ciliate-E2b 72-158 23 2.3e-10 27.87 In-house 59-146 (272) Show / Hide 
Range on Protein: 72-158
Range on HMM: 59-146/272
Sequence Identity: 23% (21 aa)

HPFIARYIQHFEDDKYVYIILEPMKGGPFKELLEAKT--RWNETQSRSIFIQLFMAIEYMQTAMAMVHGNICLDVFMVDENNYIRLVDF
|||| ..|. | ||...| ..|  .|. . ...        .. .|. .. ..  ..|| .     ... |     |||.. |..|.|.
HPFIMKFIRSFKDDQHMYFMMEFCNGMELFDVIREIGRLLLSTYDSQFYIASICLCLEYLH-NQNIIYRDIKPENIMVDHKGYMKLIDM
Kinase 94687.m00137.AA CAMK 32-129 14 5.7e-10 27.57 In-house 13-195 (425) Show / Hide 
Range on Protein: 32-129
Range on HMM: 13-195/425
Sequence Identity: 14% (27 aa)

AHHTISN------------QEVSAKIYSKQFLAK-------------------------EHNQEYFENDIYCFKT-------FYHPFIARYIQHFED---
. |. ..            |.| .||..|. | .                         ..... ... | . |.         || | . ....||   
CIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKLYEVYEDPHY

----------------DKYVYIIL---EPMKGG----PFKELLEAK---------------TRWNETQSRSIFIQLFMAIEYM
                ||..|...   | . ||       . . ..                | .| . | .| |.  |..|.
FKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYC
Kinase 94687.m00137.AA RSK 72-129 22 9.7e-09 28.44 In-house 60-120 (278) Show / Hide 
Range on Protein: 72-129
Range on HMM: 60-120/278
Sequence Identity: 22% (14 aa)

HPFIARYIQHFEDDKYVYIILEPMKGGPFKELLEAKTR---WNETQSRSIFIQLFMAIEYM
|||| ..   |......|.|.| ..|| . . |. . .   . |.  . .. .. .|.|..
HPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHL
Kinase 94687.m00137.AA CAMKL 68-129 20 4e-08 21.86 In-house 67-143 (297) Show / Hide 
Range on Protein: 68-129
Range on HMM: 67-143/297
Sequence Identity: 20% (16 aa)

KTFY---HPFIARYIQHFEDDKY------VYIILEPMKGGP--FKELLEAK----TRWNETQSRSIFIQLFMAIEYM
| .    || | .  ...|....      .|...|   ||     . ....     |  | . | .| |.  |..|.
KMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYC
Kinase 94687.m00137.AA AGC 72-158 23 5.3e-07 12.59 In-house 89-199 (395) Show / Hide 
Range on Protein: 72-158
Range on HMM: 89-199/395
Sequence Identity: 23% (26 aa)

HPFIAR-YIQHFEDDKY--VYIILEPMK---------GG-PFKELLE---AKTRWNETQSRSIFIQ-------LFMAIEYMQTAMAMVHGN-ICLDVFMV
|||| .     |.|...  .|...| |.         ||  .   |     . | .| ..| .. .       . .|.||.   |  .|   . ..  . 
HPFIVKILHYSFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILL

DENNYIRLVDF
||. .|.|.||
DEDGHIKLTDF
Kinase 94687.m00137.AA Pkinase 72-129 22 5.7e-07 25.72 Pfam 59-124 (293) Show / Hide 
Range on Protein: 72-129
Range on HMM: 59-124/293
Sequence Identity: 22% (15 aa)

HPFIARYIQHFEDDKYVYIILEPMKGG----PFKELLE--AKTRW--NETQSRSIFIQLFMAIEYM
||.| |..  |||....|...| . ||      .....  ....    | . .... |.. ..||.
HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYC
Kinase 94687.m00137.AA Aur 72-129 30 2e-06 12.6 In-house 58-117 (257) Show / Hide 
Range on Protein: 72-129
Range on HMM: 58-117/257
Sequence Identity: 30% (18 aa)

HPFIARYIQHFEDDKYVYIILEPMKGGPFKELLEAK--TRWNETQSRSIFIQLFMAIEYM
|| | ..  .|.||...|.|||   ||   ..|  .   | .| ..  .. |.  |..|.
HPNILKMYGYFHDDQRIYLILEYAPGGELYKELQKQPNKRFDEQRAAKYMYQICNALDYC
TyrKc 94687.m00137.AA TyrKc 21-264 17 3.6e-05 -139.08 SMART 1-280 (280) Show / Hide 
Range on Protein: 21-264
Range on HMM: 1-280/280
Sequence Identity: 17% (51 aa)

VFINE----------RYAIWNAHHTISNQEV---SAKIYSKQFLAKEHNQEYFENDIYCFKTF--YHPFIARYIQHFEDD-------KYVYIILEPMKGG
.  ..          . ..|.       ..|   . | ..         .| | . .   . .   || | | .    ..       . ..|..| |..|
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA---------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHG

PFKELLEAKTR-WNETQSRSIFIQLFMAIEYMQTAMAMVHGNICLDVFMVDENNYIRLVDFWGI-QPINNC----SNSQTLVF-----NK--IPFQ--TP
  |. | .. .  .  .  |. .|     ||    .  .|  .     .|.||. ..  || |    | .      .... .       |  .|     |
DLKDYLRKHRPKLCMKDLLSFCWQIACGMEYL-HSKNCIHRDLAARNCLVGENHTVKISDF-GLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAP

EYLNTGIITPSADIWALGVFLYFIC-VGSSPFST---------DTIESVTKMDILYPSFL---------SGPITDLLKKLISLSPAHRLNFRAIKEHPWF
| .|.|. |.  |.|. || .. |.  | .| .          . || | . . . .            .  . .. |.     |. | .|..|  |  |
ECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF