Gene 94489.m00090 (T.vaginalis)

94489.m00090

Species: T.vaginalis
Alias: TvagK0981, 94489.m00090
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
94489.m00090.AA Protein None 285 None Fasta, JSON
94489.m00090.kin_dom Protein Kinase Domain None 126 None Fasta, JSON

Protein domain

Protein domains of 94489.m00090.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 94489.m00090.AA Ciliate-E2-Unclassified 59-185 20 5.3e-20 66.09 In-house 77-257 (352) Show / Hide 
Range on Protein: 59-185
Range on HMM: 77-257/352
Sequence Identity: 20% (38 aa)

NLRFPSIIQLYHIEKIDNELDFFQEFFPYGDLTKFEEY------------------NYIGENIIA-----QFFYQCARGLQYLHNQG-YIHRDIKPPNIF
|.  | |. ...... .. . .  |....||| .. .                   . . |. ..     ..|.|   ||.||| ..  ||||||| ||.
NHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENIL

IDKNK---NASLEDLENST-------------------NDPDSQSAYGNGTYA----APEIYKEGQNT----KKSDIYSIG
.|.|.   .  . |. .|                     .  ...  |.  |     |||.... ..     .|.||.| |
FDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLG
Kinase 94489.m00090.AA Ciliate-E2 83-188 20 5.6e-20 65.25 In-house 114-286 (365) Show / Hide 
Range on Protein: 83-188
Range on HMM: 114-286/365
Sequence Identity: 20% (36 aa)

EFFPYGDLTKFEEYN------------YIGENIIAQFFYQCAR---------------GLQYLHNQG-YIHRDIKPPNIFIDKNKNASLEDLENSTNDPD
|.. .||| .. . |            |. |. |.....| ..               .|.|||...  ||||||| ||..       . |. .|..  |
EYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDD

SQSA-----------------------------------YGNGTYAAPEIYKEGQ---------NTKKSDIYSIGATF
..                                     .|.  | ||||.. ..          ..|.||.|.| ..
DNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVIL
Kinase 94489.m00090.AA STE 72-187 25 1e-16 55.69 In-house 106-257 (359) Show / Hide 
Range on Protein: 72-187
Range on HMM: 106-257/359
Sequence Identity: 25% (41 aa)

EKIDNELDFFQEFFPYGDLTKFEEYNYIG---------------ENIIAQFFYQCARG-LQYLHNQGYIHRDIKPPNIFIDKNKNASLED------LENS
.| |.||  . |. ..| |... . .|.                |..|| . .|. .| |.|||....||||||| ||..     . | |      |..|
HKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDS

--------------TNDPDSQSAYGNGTYAAPEIYKEGQNT------KKSDIYSIGAT
              |..  ...  |   . |||. . ....       |.||.|.| |
MANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCT
Kinase 94489.m00090.AA CAMK 59-185 15 9.6e-16 46.52 In-house 94-321 (425) Show / Hide 
Range on Protein: 59-185
Range on HMM: 94-321/425
Sequence Identity: 15% (36 aa)

NLRFPSIIQLYHIEKI-------------------DNELDFFQ---EFFPYG----D-LTKFEEYNY---------------IGENIIAQFFYQCARGLQ
.|. | ||.||..                      |... ..    |. . |    | . .  |  .               . |   ...| | . ...
KLDHPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVH

YLHNQGYIHRDIKPPNIFIDKNK-----------------NASLEDLENSTN---------------------------DPDSQSAYGNGTYAA-PEIYK
|.|... .|||.|| || .|.|.                 |  . |   ..                            ..  .   |   |.| ||. .
YCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLN

--------------EGQNTKKSDIYSIG
              .   ..|.|. |.|
GKGHCNMQNATDEEKPYYGPKCDMWSCG
Kinase 94489.m00090.AA ULK 65-139 30 1.3e-14 47.46 In-house 80-167 (329) Show / Hide 
Range on Protein: 65-139
Range on HMM: 80-167/329
Sequence Identity: 30% (27 aa)

IIQLYHIEKID--NELDFFQEFFPYGDLTKFEEYN-----------YIGENIIAQFFYQCARGLQYLHNQGYIHRDIKPPNIFIDKNK
|..||.. . .  | . ...|. . ||| .. . |           .. |... |||.| . |...|| ...||||||| || |....
IVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQ
Kinase 94489.m00090.AA MLK 109-185 28 1.7e-14 46.86 In-house 131-223 (291) Show / Hide 
Range on Protein: 109-185
Range on HMM: 131-223/291
Sequence Identity: 28% (27 aa)

YQCARGLQYLHNQG---YIHRDIKPPNIFID------KNKNASLED--LENSTNDPDSQ---SAYGNGTYAAPEIY---KEGQNTKKSDIYSIG
.|||||..|||..    .||||.|..|| ||      .....   |  .  . .. . .   |. |.  . |||.    .......|.|..|.|
LQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWG
Kinase 94489.m00090.AA WEE 97-188 25 4.3e-14 43.75 In-house 106-226 (297) Show / Hide 
Range on Protein: 97-188
Range on HMM: 106-226/297
Sequence Identity: 25% (31 aa)

NYIGENIIAQFFYQCARGLQYLHNQ-GYIHRDIKPPNIFIDKNK--------------------NASLEDLENSTNDP----DSQSA-YGNGTYAAPEIY
... |. | |.. . ..||...|.. | .| |||| |||| |..                    .  . |.  .|. .    .....  |.. | |||| 
HWLPEWMIWQILVDICQGLHHIHSNCGMVHMDIKPENIFISKKMNCNQIVNNDQQNNNDWWFNMMCKIGDFGHVTDMNSNNNNPHQEQEGDSRYMAPEIL

K---EGQNTKKSDIYSIGATF
    .  . .|.||.|.|.|.
QGYYHYTHLYKADIFSLGITI
Kinase 94489.m00090.AA NEK 88-185 22 5.3e-14 46.05 In-house 92-165 (286) Show / Hide 
Range on Protein: 88-185
Range on HMM: 92-165/286
Sequence Identity: 22% (25 aa)

GDLTKF----EEYN----YIGENIIAQFFYQCARGLQYLHNQ-----GYIHRDIKPPNIFIDKNKNASLEDLENSTNDPDSQSAYGNGTYAAPEIYKEGQ
||| ..    ...     |. |..|  .|.| . .|.|.|..       .|||||| |||..|| | .                                
GDLYQKIKSIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDY--------------------------------

NTKKSDIYSIG
     ..  ||
-----HNVKIG
Kinase 94489.m00090.AA ULK 65-139 31 1.3e-13 44.76 In-house 77-163 (324) Show / Hide 
Range on Protein: 65-139
Range on HMM: 77-163/324
Sequence Identity: 31% (27 aa)

IIQLYHIEKID--NELDFFQEFFPYGDLTKFEEYN----------YIGENIIAQFFYQCARGLQYLHNQGYIHRDIKPPNIFIDKNK
|..||.. . .  | . ...|. . ||| .. . |          .. |... |||.| . |...||....||||||| || | ...
IVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQ
Kinase 94489.m00090.AA Pkinase 65-138 32 7.3e-13 46.57 Pfam 62-144 (293) Show / Hide 
Range on Protein: 65-138
Range on HMM: 62-144/293
Sequence Identity: 32% (27 aa)

IIQLYHIEKIDNELDFFQEFFPYG----DLT----KFEEYNYI--GENIIAQFFYQCARGLQYLHNQGYIHRDIKPPNIFIDKN
|..||..   .... . .|. . |    ||       .... .   |. .  ..|| .|||.|.|..| ||||.|| ||.||.|
IVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST-WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNN
S_TKc 94489.m00090.AA S_TKc 20-234 19 2.3e-12 4.36 SMART 1-231 (231) Show / Hide 
Range on Protein: 20-234
Range on HMM: 1-231/231
Sequence Identity: 19% (50 aa)

NSDLKK-----GANVHLLFHRETGILLTRKNVAICNWSQQTNR-----MNLRFPSIIQLYHIEKIDNELDFFQEFFPY--GDLTK-FEEYNY------IG
   |.|      . |..  |..|| .   | .      ... |     .. . | |..|| .    ..| .. |. .   ||| .  .....      . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

ENIIAQFFYQCARGLQYLHNQGYIHRDIKPPNIFIDKNKNASLEDLENSTNDPDSQSAYGNGTYAAPEIYKEGQNTK-KSDIYSIGATF-----------
|  .. ..|| ...|.|.|..| ||||.|| ||..|.  .  . |   ..      .  |   | |||.    . .| |.|..|.| ..           
E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP

-EEYILKIQGDDDFKNDLLDIVSQTKAEEPDNRISADDLVS-----QLEELL
 .. ..|. |      ...|....    .|..|..| ..        . . .
QMQMMFKKIG----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 94489.m00090.AA NZAK 112-163 41 7.4e-11 32.19 In-house 115-167 (329) Show / Hide 
Range on Protein: 112-163
Range on HMM: 115-167/329
Sequence Identity: 41% (22 aa)

ARGLQYLHNQGYIHRDIKPPNIFIDKNKNASLEDLENSTNDPDSQS-AYGNGT
|... ||| .. ||||||. |.  |.|||  | |   |. .   |.  | | |
AETMSYLHKHHIIHRDIKSNNVILDFNKNLKLIDFGSSIIQQQYQFEQYLNET
TyrKc 94489.m00090.AA TyrKc 31-230 17 8.3e-07 -112.57 SMART 1-280 (280) Show / Hide 
Range on Protein: 31-230
Range on HMM: 1-280/280
Sequence Identity: 17% (50 aa)

LLFHRE----------TGILLTRKNVAICNWSQQTNR----------MNL--RFPSIIQLYHIEKID-------NELDFFQEFFPYGDLTKFEEYNY--I
. . ..           |..    .||.      . |          ..|  . | |..|| .   .         |    |. |.||| ..  ..   .
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKL

GENIIAQFFYQCARGLQYLHNQGYIHRDIKPPNIFIDKNK-----------NASLEDLENSTNDPDSQSAYG-----NGT------YAAPEIYKEGQNTK
      .| .| |.| .||| ...||||.   |. ...|.           .   .| .       |.. |      .|         |||  ..|  | 
CMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG-----ESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

KSDIYS----------------IG--------ATFEEYILKIQGDDDFKN-----------DLLDIVSQTKAEEPDNRISADDLVSQL
|||..|                 |        .   ||. .    .  .|           .. .| .|  .|.|..| .  ......
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 94489.m00090.AA NZAK 164-187 41 7.5e-05 11.66 In-house 238-261 (329) Show / Hide 
Range on Protein: 164-187
Range on HMM: 238-261/329
Sequence Identity: 41% (10 aa)

YAAPEIYKEGQNTKKSDIYSIGAT
| |||  .    ..|||..|.| |
YMAPENKNNHRINEKSDVWSFGCT
Kinase 94489.m00090.AA ULK 164-185 33 0.00062 9.72 In-house 217-243 (329) Show / Hide 
Range on Protein: 164-185
Range on HMM: 217-243/329
Sequence Identity: 33% (9 aa)

YAAPEIYKEG-----QNTKKSDIYSIG
| ||.| ..      ....|.||.|.|
YMAPQILQGQGEQKPYYDYKCDIWSLG
Kinase 94489.m00090.AA Pkinase_Tyr 106-128 43 0.000645 13.89 Pfam 115-137 (270) Show / Hide 
Range on Protein: 106-128
Range on HMM: 115-137/270
Sequence Identity: 43% (10 aa)

QFFYQCARGLQYLHNQGYIHRDI
|. .| |.|..||.....||||.
QMCWQIAKGMEYLESKNCIHRDL
Kinase 94489.m00090.AA ULK 164-185 33 0.000815 9.49 In-house 213-239 (324) Show / Hide 
Range on Protein: 164-185
Range on HMM: 213-239/324
Sequence Identity: 33% (9 aa)

YAAPEIYKEG-----QNTKKSDIYSIG
| ||.| ..      ....|.||.|.|
YMAPQILQGQGEQKPYYDYKCDIWSLG
Kinase 94489.m00090.AA Pkinase 164-185 34 0.420652 4.98 Pfam 177-199 (293) Show / Hide 
Range on Protein: 164-185
Range on HMM: 177-199/293
Sequence Identity: 34% (8 aa)

YAAPEIYK-EGQNTKKSDIYSIG
|.|||. .     ..|.|..|.|
YMAPEVIRGGQYYGPKVDMWSCG
Kinase 94489.m00090.AA Pkinase_Tyr 214-230 23 2.329273 1.84 Pfam 254-270 (270) Show / Hide 
Range on Protein: 214-230
Range on HMM: 254-270/270
Sequence Identity: 23% (4 aa)

AEEPDNRISADDLVSQL
...|..| .  ....||
HYDPEDRPTFSEIHEQL