Gene 91452.m00056 (T.vaginalis)

91452.m00056

Species: T.vaginalis
Alias: 91452.m00056, TvagK0968
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
91452.m00056.AA Protein None 308 None Fasta, JSON
91452.m00056.kin_dom Protein Kinase Domain None 204 None Fasta, JSON

Protein domain

Protein domains of 91452.m00056.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 91452.m00056.AA Ciliate-E2 54-265 21 1.7e-35 119.32 In-house 70-365 (365) Show / Hide 
Range on Protein: 54-265
Range on HMM: 70-365/365
Sequence Identity: 21% (67 aa)

YRAMECYN----NEKDILGSVIHPNIAETFDFFT--SKNHAFLIFELCKDLSLETLVSIPCSC-----------TEKSIYGYISQIIH------------
.| ..|      ||| || .. |||| . ...|   ..|. .|..|.|.  .|. .  . . .           ||| |  .. ||.             
MREINC-FYKKINEKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIAC

---GISHLHANS-IAHNNINPSNIMFDRFGRIKIVDFDHSIFTNDQ-------PLCS--------------------------FTGTTRFPRAPESLNSK
   .. .|| .  | | .| |.||.|     |||.||  | . .|.       ..|                           . ||  .  ||| ||.|
IILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGY-MAPEILNGK

LYDP--------IAADIWGFGAVSYFLLSGEYPWSPELECSYSEAITNSIKK----------------------IYGKFDEKLIQLIVN----CLSENPT
 ||          ..||| .| . |..|.|..|.             . ||.                      .. | ... ..|| .    .|  .| 
KYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPE

DRPS---SAAIHSYL
 |..    .  | ..
KRITGWEQILNHPWF
Kinase 91452.m00056.AA Ciliate-E2-Unclassified 64-265 22 3.8e-31 105.28 In-house 72-352 (352) Show / Hide 
Range on Protein: 64-265
Range on HMM: 72-352/352
Sequence Identity: 22% (64 aa)

KDILGSVIHPNIAETFDFFTSKNHAFLIFELCKDLSLETLVSIP-----------------CSCTEKSIY-----GYISQIIHGISHLHANS-IAHNNIN
..|| .  ||.|   |. |..|.. ... |.|....|.   ..                  .  ||. .       |. ||. |...|| .  | | .| 
QQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIK

PSNIMFDRFG---RIKIVDFDHSI-----------------FTNDQPLCSFTGTTRF-PR--APESLNSKLYDP---IAADIWGFGAVSYFLLSGEYPWS
|.||.||  |   .||| ||  |.                 .. .| ...|.|| .. |.  ||| | .. ||    ...|||..| . |..| |.|| .
PENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFY

----PELECSYSEAITN------SIKKIYGK---------------FDEKLIQLIV----NCLSENPTDR--PSSAAIHSYL
     . ... .. | |       ...|. |                ... . .|      .|  ||  |  .. .  | ..
DNNCEQHQQLITQWI-NNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 91452.m00056.AA CAMK 62-261 16 6e-27 83.27 In-house 80-419 (425) Show / Hide 
Range on Protein: 62-261
Range on HMM: 80-419/425
Sequence Identity: 16% (55 aa)

NEKDILGS-------VIHPNIAETFDFFTS-------------------KNHAFLIF---ELCK--DL--S-LETLVSIPC--------------SCTEK
.| .|. .       . ||||   .... .                   ..| ....   |.|   .|    .. .|. .|                ||.
REIEIMKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTER

SIYGYISQIIHGISHLHANSIAHNNINPSNIMFD-RF----------------GRIKIVDFDHS--IFTN-----------------------DQPLCSF
    |. ||. .. ..| . |.|  . | ||..| ..                . |||.||  .  .. .                       .|..  |
EARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTF

TGTTRFPRA-PESLNS-------------KLYDPIAADIWGFGAVSYFLLSGEYPWSPE-LECSYS--------EAITNSIKKIYGKFDEK---------
 ||  .  | || ||.             | |.. ..|.|  | . |..|.|..|.  .  .. ..        . .   |.|    |...         
CGTPEY-MAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNY

-------------------LIQLIVNCLSENPTDRPSSAAI
                    ..|| ..|  .|..|.. . .
GPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQC
Kinase 91452.m00056.AA Pkinase 72-265 22 6.8e-24 85.56 Pfam 59-293 (293) Show / Hide 
Range on Protein: 72-265
Range on HMM: 59-293/293
Sequence Identity: 22% (53 aa)

HPNIAETFDFFTSKNHAFLIFELCKDL----SLETLVS--IPCSC--TEKSIYGYISQIIHGISHLHANSIAHNNINPSNIMFDRFGRI----KIVDFDH
|||| ...|.|..|.|  ...|.|       .| ...|    ..   .|. .  |. ||. |. ..|...| |  . |.||..|. | |    || ||  
HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGL

SI---FTNDQPLCSFTGTTRFPRAPESLNSKLYDPIAADIWGFGAVSYFLLSGEYPWSPE--------LECSYSEAITNSIKKIYGKFD-----------
.      |.. . .|.|| .. .||| ...  |.. ..|.|..| . | .|.|. |.. .        ... .    .     .. . .           
AKQFDY-NNS-MTTFCGTPWY-MAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHF

--------EKLIQLIVNCLSENPTDRPS--SAAIHSYL
        | ....| .||  .|..||.   .  | ..
HWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 91452.m00056.AA CAMKL 72-257 24 3.8e-21 64.1 In-house 74-287 (297) Show / Hide 
Range on Protein: 72-257
Range on HMM: 74-287/297
Sequence Identity: 24% (54 aa)

HPNIAETFDFFTSKNH------AFLIFELCKDL---SLETLVSIPC---SCTEKSIYGYISQIIHGISHLHANSIAHNNINPSNIMFDRFG--RIKIVDF
||||   .. .. ..|       .|. |.|       .. .|. ..   . .|.    |  ||.......| . |.|  | | ||..|  |   |||.||
HPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDF

DHS-----I-FTNDQPLCSFTGTTRFPRAPESLNS--KLYDPIAADIWGFGAVSYFLLSGEYPWS-PEL------ECSYSEAITNSIKKIYGKF---DEK
  |     . |...| |  | |.  .  ||| ...  | ||  ..|||  | . |... |..|.  . .         | . ....  . . ..   .  
GFSNMYRPCIFGPGQKLKTFCGSPPY-MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-D

LIQLIVNCLSENPTDRPS
...||   |  ||..||.
CRDLIRKMLQVNPEKRPT
Kinase 91452.m00056.AA PLK1 63-267 28 5.4e-18 55.49 In-house 49-253 (253) Show / Hide 
Range on Protein: 63-267
Range on HMM: 49-253/253
Sequence Identity: 28% (59 aa)

EKDILGSVIHPNIAETFDFFTSKNHAFLIFELCKDLSLETLVSIPCSCTEKSIYGYISQIIHGISHLHANSIAHNNINPSNIMFDRFGRIKIVDFDHSIF
| .|  .. |..| . ..||  |.  ... |||.  ||  |     . ||     |. ||..|. .|| | | |  .   |. ..   ..|| ||    .
EIQIHRQLHHRHIVKFHHFFEDKQNVYIVLELCRRRSLMELHKRRKAITEPECRYYMYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHLQVKIGDFGLATK

TNDQ--PLCSFTGTTRFPRAPESLNSKLYDPIAADIWGFGAVSYFLLSGEYPW-SPELECSYSEAITNSIKKIYGKFDEKLIQLIVNCLSENPTDRPSSA
 . .        ||  .  ||| || |       |||  | . | || |. |. .  |.  ||  | .   .|  .  .   |||.. | ..|| ||   
CEYDGERKKTLCGTPNY-IAPEVLN-KKGHSFEVDIWSIGCIMYILLFGQPPFETKCLKETYSR-IKKNEYRIPSHISQPAAQLIRKMLDPDPTRRPTIE

AIHSYLSN
.. .    
QVLNDEFF
Kinase 91452.m00056.AA TKL 55-265 15 1.8e-17 59.44 In-house 67-364 (364) Show / Hide 
Range on Protein: 55-265
Range on HMM: 67-364/364
Sequence Identity: 15% (49 aa)

RAMECYNNEKDILGSVIHPNIAETFDFFTSKNH-------------AFLIFELCKDLS-LETLVSIPCSCTEKSIYGYISQIIHGISHLHANS-------
..... ..|  .. .  ||||     . .. ..              ... |.|.  | |..|           .   . .|  |...||..        
WFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKP

-IAHNNINPSNIMFDRFGR--------------IKIVDFDHSIFTNDQP---------------------LCSFTGTTRFPRAPESLNSKLYDPIAA---
 |.| .....||. |. ..              .|| ||  | | .                        ...  ||.|.  ||| |. ..... ..   
PIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRW-MAPEVLRGQMNYTEKVGID

------------DIWGFGAVSYFLLSGEYPWSPELECSYSEAI---------TNSIKKIY-----------------GKFDEKLIQLIVNCLSENPTDRP
            |.. || | . .|...    |. .  |.. |            ..| .                   ... ...|.  | ...|..||
EFCKGFEYSEKCDVYSFGIVLWEILTRCR---PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRP

SSAAIHSYL
|   | ..|
SFQEILKRL
S_TKc 91452.m00056.AA S_TKc 18-265 23 1.3e-16 62.39 SMART 1-231 (231) Show / Hide 
Range on Protein: 18-265
Range on HMM: 1-231/231
Sequence Identity: 23% (63 aa)

YTIILTISDTPSSKHIEVTKGK-GFSFDAKIYKLKGNYRAMECYNNEKDILGSVIHPNIAETFDFFTSKNHAFLIFELCKD--LSLETLVSIPCS-----
|.|. .|     .|   ... | |  .  || |        |   .| .|| .  ||||   .|.| . .| ....|.|     .| ..     .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-CTEKSIYGYISQIIHGISHLHANSIAHNNINPSNIMFDRFGRIKIVDFDHSIFTNDQPLCSFTGTTRFPRAPESLNSKLYDPIAADIWGFGAVSYFLLS
  .|  .  |. ||. .. ..| . | |  . |.||..|.  .||| ||  . .       .| ||  . .||| |    |.. ..|.| .| . | .|.
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWY-MAPEVL---GYGKCKCDWWSCGCILYEMLC

GEYPWSPELECSYSEAITNSIKKIYGKFDEKLIQLIVNCLSENPTDRPSSAAIHS---------YL
|. |..          .   .|||    .. ....| .||  .|..||.   .           ..
GYPPFP---------QMQMMFKKIG---SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 91452.m00056.AA GIN4 72-216 28 7.9e-16 46.63 In-house 93-238 (293) Show / Hide 
Range on Protein: 72-216
Range on HMM: 93-238/293
Sequence Identity: 28% (42 aa)

HPNIAETFDFFTSKNHAFLIFELCKDLSLETLVSIPCSCTEKSIYGYISQIIHGISHLHANSIAHNNINPSNIMFDRFGR-IKIVDFDHSIFTNDQPLCS
|||. . .| .  .|  .|. |      |  ..       |.    |  ||| |.|  ||  | |  . | |.. |.. . ||| ||       |. |  
HPNVMRLYDVWETNNDLYLVLEYAEKGELFNYLVDHGPLPEREAIHYFRQIIIGVSYCHAFNICHRDLKPENLLLDHKYNRIKIADFGMAALETDNKLLE

FTGTTRFPRAPESLNSKLYDPIAADIWGFGAVSYFLLSGEYPWSPE
         |||      |.  |.|.|  | . . || |  |.  |
TSCGSPHYAAPEIVMGIPYHGFASDVWSCGVILFALLTGHLPFDEE
Kinase 91452.m00056.AA STE 72-258 18 1.2e-15 51.88 In-house 89-348 (359) Show / Hide 
Range on Protein: 72-258
Range on HMM: 89-348/359
Sequence Identity: 18% (50 aa)

HPNIAETFDFFTSK-------NHAFLIFELCKDLSLETLVSI--PCSCT------------EKSIYGYISQIIHG-ISHLHANSIAHNNINPSNIMFDRF
|||| . .. .  .       .. ... |..   ||. ..     | ..            |. |  .. ||..|  ..|| . | |  | |.||..   
HPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL---

GRIKIVDFDHSIFTND-----------------QPLC-SFTGTTRFPRAPESLNS------KLYDPIAADIWGFGAVSYFLLSGEYPWSPELECSYSEAI
  .|..|| ..   .|                 |  . .|.||     ||| ..       | || . .||| .| .   .. |..||. .   .   .|
--VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP--WMAPEVIQQNGQGRDKGYD-TKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMI

TNSI-------------------KKI----------------YGKFDEKLIQLIVNCLSENPTDRPSS
....                   .                    |. ..... | .||  .| .||..
PFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTA
Kinase 91452.m00056.AA ULK 56-157 24 1.2e-10 34.0 In-house 53-182 (324) Show / Hide 
Range on Protein: 56-157
Range on HMM: 53-182/324
Sequence Identity: 24% (32 aa)

AMECYNNEKDILGSVI---HPN--IAETFDFFTSK--NHAFLIFELCKDLSLETLVSIPCSCTEKS----------IYGYISQIIHGISHLHANSIAHNN
...  .||  |.       |||  | . .|.| ..  |. ..|.|.| .  ||..      ..|            . ... ||. |  .|| . | |  
MWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRD

INPSNIMFDRF------------GRIKIVDF
| |.||.                |..|| ||
IKPQNILIHNGQPKTDSKKVHPNGVLKIADF
Kinase 91452.m00056.AA ULK 56-157 23 1.5e-10 33.11 In-house 53-186 (329) Show / Hide 
Range on Protein: 56-157
Range on HMM: 53-186/329
Sequence Identity: 23% (32 aa)

AMECYNNEKDILGSVI--------HPNIAETFDFFTSK--NHAFLIFELCKDLSLETLVS----------IPCSCTEKSIYGYISQIIHGISHLHANSIA
.... .|| .|.            |||| . .|.| ..  |. ..|.|.| .  ||.. .           .   .|. .  .. ||. |  .|| . | 
MWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNII

HNNINPSNIMFDRF------------GRIKIVDF
|  | |.||. .              |..|| ||
HRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADF
TyrKc 91452.m00056.AA TyrKc 34-265 19 4.6e-07 -108.5 SMART 14-280 (280) Show / Hide 
Range on Protein: 34-265
Range on HMM: 14-280/280
Sequence Identity: 19% (53 aa)

EVTKGKGFSFDAKIYKLKGNYRAMECYNNEKDILGSV--IHPNIAETFDFFTSK-------NHAFLIFELCKDLSLETLVSIPCS-CTEKSIYGYISQII
|| ||.    .  . .|| .   .|   .|  |. ..   ||||   .   |..          ....|...  .|      .    . |    .  || 
EVYKGTWK-IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIA

HGISHLHANSIAHNNINPSNIMFDRFGRIKIVDFDHSIFTNDQ-------PLCSFTG--TTR--FP---RAPESLNSKLYDPIAADIWGFGAVSYFLLS-
 | ..|| . . |  .   |.. .. ...|| ||  | .  |           . ..   ..  .|    |||..| . .  .. |.| || . . ... 
CGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-TKSDVWSFGVCMWEIFTY

GEYPWSPELE--CSYSEAITNSIKK----IYGK--------FDEKLIQLIVNCLSENPTDRPSSAAIHSYL
|. |.. . .  .| .|.| .  .     .             ... |..  |  |.| |||. ..||...
GQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 91452.m00056.AA ULK 180-255 19 5e-06 17.29 In-house 219-317 (329) Show / Hide 
Range on Protein: 180-255
Range on HMM: 219-317/329
Sequence Identity: 19% (19 aa)

APESLNSKL----YDPIAADIWGFGAVSYFLLSGEYP---WSPELEC-----SYSEA-------ITNSIKKIY-----GKFDEKLIQLIVNCLSENPTDR
||. |....    |.   .||| .| . | .| |..|   | .. .      .  .        | .   ...      .. .....||  .|  ...||
APQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDR
Kinase 91452.m00056.AA ULK 180-255 22 1.8e-05 15.45 In-house 215-312 (324) Show / Hide 
Range on Protein: 180-255
Range on HMM: 215-312/324
Sequence Identity: 22% (22 aa)

APESLNSKL----YDPIAADIWGFGAVSYFLLSGEYP---WSPELEC----SYSEA-------ITNSIKKIY-----GKFDEKLIQLIVNCLSENPTDR
||. |....    |. . .||| .| . | .| |.||   | .. .     .  .        | |   ...      |. .....||  .|  ...||
APQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDR