95258.m00098

Species: T.vaginalis
Alias: 95258.m00098, TvagK0911
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
95258.m00098.AA Protein None 193 None Fasta, JSON
95258.m00098.kin_dom Protein Kinase Domain None 128 None Fasta, JSON

Protein domain

Protein domains of 95258.m00098.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 95258.m00098.AA Ciliate-E2 76-190 19 2.1e-14 45.82 In-house 115-293 (365) Show / Hide
Range on Protein: 76-190
Range on HMM: 115-293/365
Sequence Identity: 19% (36 aa)

LIKGDDLYYYLEKNKASDAEK---------LVWIYFIADQL------------------ETLHKNK-IIHRDICPKNIRIDTKHYPHIIDYDDVQKTDNP
...| ||..|...|| .  ..            .|... .|                  | ||... |||||| | || .     . |||    .| |..
YCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDD

-----------MMTSKR----------------------HGTGLYHSLEVIKSLD---------YTPASDIFALGGVIYYIMTGN
           ...  .                       ||  | . |.... .         |. ..||..|| ..|. ..|.
NQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

Kinase 95258.m00098.AA Ciliate-E2-Unclassified 79-190 25 4.9e-14 45.1 In-house 122-267 (352) Show / Hide
Range on Protein: 79-190
Range on HMM: 122-267/352
Sequence Identity: 25% (37 aa)

GDDLYYYLEKNKASDAEKLV------WIYFIADQLETLHKNK-IIHRDICPKNIRIDTKH---YPHIIDYDDVQKTDN----------------PMMTSK
|.||.  ....|  . .. .      ... | . || ||... |||||| | || .| ..   |. |||.    | ..                ..|.. 
GNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWT

RHGTGLYH----SLEVIKSLDYT----PASDIFALGGVIYYIMTGN
. ||  |     . ||...  |      ..||..|| ..|....|.
FCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGY

Kinase 95258.m00098.AA Pkinase 79-192 28 1.9e-09 34.52 Pfam 84-211 (293) Show / Hide
Range on Protein: 79-192
Range on HMM: 84-211/293
Sequence Identity: 28% (37 aa)

GD----DLYYYLE---KNKA--SDAEKLVWIYFIADQLETLHKNKIIHRDICPKNIRIDTKHYP----HIIDYDDVQK--TDNPMMTSKRHGTGLYHSLE
|.    ||. |..   ...   |. |   ..| |.  || .|...|||||. | || || . ..    .|.|     .  . |   .. . ||  | . |
GGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPE

VIK-SLDYTPASDIFALGGVIYYIMTGNEP
||. . .|.|..|....| ..|. ..|. |
VIRGGQYYGPKVDMWSCGCILYEMLCGRPP

Kinase 95258.m00098.AA Ciliate-E2b 107-137 54 6.8e-08 20.25 In-house 115-145 (272) Show / Hide
Range on Protein: 107-137
Range on HMM: 115-145/272
Sequence Identity: 54% (17 aa)

LETLHKNKIIHRDICPKNIRIDTKHYPHIID
|| ||...||.||| | || .| | |. .||
LEYLHNQNIIYRDIKPENIMVDHKGYMKLID

Kinase 95258.m00098.AA Eta 107-192 29 6e-07 19.55 In-house 113-199 (261) Show / Hide
Range on Protein: 107-192
Range on HMM: 113-199/261
Sequence Identity: 29% (26 aa)

LETLHKNKIIHRDICPKNIRIDTKHYPHIIDYDDVQK-TDNPMMTSKRHGTGLYHSLEVIKSLDYTPASDIFALGGVIYYIMTGNEP
|  ||.. .| ||.   || .|     .. |.   .    | |.|.   ||  |   |... ..| |. | .|.| ..| .|.|. |
LMFLHQHGVIYRDLKLDNILLDHEGHCKLADFGMCKEGIMNGMTTTTFCGTPDYIAPEILQEMEYGPSVDWWAMGVLMYEMMCGQPP

Kinase 95258.m00098.AA NEK10 110-184 39 3e-06 16.19 In-house 135-211 (279) Show / Hide
Range on Protein: 110-184
Range on HMM: 135-211/279
Sequence Identity: 39% (31 aa)

LHKNK-IIHRDICPKNIRIDTKHYPHIIDYD-DVQKT-DNPMMTSKRHGTGLYHSLEVIKSLDYTPASDIFALGGVIY
||| | |.|||  | || . .|    | |.    ||  |.  |||   || ||   |...|. |    |. | | ..|
LHKEKQIVHRDLTPNNIMMGDKDRVTITDFGLAKQKQPDPSKMTS-VVGTILYSCPEIVQSEPYGEKADVWAFGCCLY

Kinase 95258.m00098.AA PKR 103-180 37 5e-06 17.44 In-house 132-210 (272) Show / Hide
Range on Protein: 103-180
Range on HMM: 132-210/272
Sequence Identity: 37% (30 aa)

IADQLETLHKNKIIHRDICPKNI-RIDTKHYPHIIDYDDVQKTDNPMM-TSKRHGTGLYHSLEVIKSLDYTPASDIFALG
|    . .|  |.||||. | ||  .|..|   | |.  |   .|      .|.||  | | | | | .|    ||.|||
IVKGVDYIHSKKLIHRDLKPSNIFLVDERHI-KIGDFGLVTALKNDGKSRTRRKGTLQYMSPEQIFSQHYGKEVDIYALG

Kinase 95258.m00098.AA Ciliate-E1 17-177 19 6e-06 15.78 In-house 19-202 (202) Show / Hide
Range on Protein: 17-177
Range on HMM: 19-202/202
Sequence Identity: 19% (36 aa)

ENEGILRKIYSNSSFVANNRKGVINKILETAKLQKENIFLQELIDIHKNDDGSLYADFRLIKGDDLYYYL-------------EKNKASDAEKLVWIYFI
.|. ..  |  .  .. |.   .|... .  |..||   .| .  | . .    .. |.. .  .. |               ..|. .. .|.  |. .
YNQVAQKIINCCFNYNQNHFQDEIKEYYKIMKFKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQCQQNQNQFTFQQKMQIIFQL

ADQLETLHKNKIIHRDICPKNIRIDTKHYPHIID---------YDDVQKTDNPMMTSKRHGTGLYHSLEV--IKSLDYTPASDIF
 |.|. || ..|||||| |.|| |. .   ...          . . | ..   .|..   .  | . |.  .|.  ..  |||.
IDGLIELHQYNIIHRDIKPQNILINNQ-GNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKSDIY

Kinase 95258.m00098.AA Fer 76-120 43 9e-06 15.75 In-house 90-137 (283) Show / Hide
Range on Protein: 76-120
Range on HMM: 90-137/283
Sequence Identity: 43% (21 aa)

LIKGDDLYYYLEKNKA---SDAEKLVWIYFIADQLETLHKNKIIHRDI
...|..|  || |||.   ||.||.  .| .|. .| ||....|||||
FCNGGSLDSYLKKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDI

Kinase 95258.m00098.AA PDK1 107-125 68 2.2e-05 11.88 In-house 123-141 (307) Show / Hide
Range on Protein: 107-125
Range on HMM: 123-141/307
Sequence Identity: 68% (13 aa)

LETLHKNKIIHRDICPKNI
|| ||.|.|||||. | ||
LEHLHSNGIIHRDLKPENI

Kinase 95258.m00098.AA IRE 155-189 36 0.000166 11.06 In-house 191-228 (292) Show / Hide
Range on Protein: 155-189
Range on HMM: 191-228/292
Sequence Identity: 36% (14 aa)

GTGLYHSLEVIKS---LDYTPASDIFALGGVIYYIMTG
||. .| .|....      | . ||| .| |.||.||.
GTWGWHPPEMLQEFCQKRKTKSVDIFSMGCVFYYVMTN

S_TKc 95258.m00098.AA S_TKc 16-193 19 0.000264 -113.79 SMART 1-220 (231) Show / Hide
Range on Protein: 16-193
Range on HMM: 1-220/231
Sequence Identity: 19% (46 aa)

FENEGILRKIYSNSSFVANNRK-GVIN--KILETAKLQKENIFLQ-------ELIDIHKNDDGSLYADFRLIKG--DDLYYYLEKNK-------ASDAEK
.|   .. |    . . . ..| | |   ||.   ....|   |.        |.|.  .  ..||  . .. |   ||. |..|..        .  . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-EHIRREIQILKKHHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HA

LVWIYFIADQLETLHKNKIIHRDICPKNIRIDTKHYPHIIDYDDVQKTDNPMMTSKRHGTGLYHSLEVIKSLDYTP-ASDIFALGGVIYYIMTGNEP---
  ..| |.. || .|...|||||. | || .|.     |.|     .       .   ||  | . ||.    |.. ..|. .. |.| |.|   .|   
RFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSC-GCILYEMLCGYPPFP

-----------------------------------N
                                   .
QMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTAEALQ

Kinase 95258.m00098.AA Fer 163-192 32 0.001354 8.24 In-house 188-218 (283) Show / Hide
Range on Protein: 163-192
Range on HMM: 188-218/283
Sequence Identity: 32% (10 aa)

EVIKSLDYTPASDIFALGGVIYYIMT-GNEP
|....  |.|..|... | ... |.| | ||
ETWQTGIYSPKTDVWSFGVMCWEIFTNGAEP

Kinase 95258.m00098.AA IRE 110-125 56 0.003002 6.63 In-house 132-147 (292) Show / Hide
Range on Protein: 110-125
Range on HMM: 132-147/292
Sequence Identity: 56% (9 aa)

LHKNKIIHRDICPKNI
||  .|.|||. | ||
LHSQNIVHRDLKPHNI

Kinase 95258.m00098.AA Ciliate-E2b 163-192 31 0.080213 1.51 In-house 175-209 (272) Show / Hide
Range on Protein: 163-192
Range on HMM: 175-209/272
Sequence Identity: 31% (11 aa)

EVIK-----SLDYTPASDIFALGGVIYYIMTGNEP
|.|.        || ..||...| . | .| |  |
EIIQSLQPGGKGYTYKVDIWSVGICLYEFMCGYVP