Gene 89470.m00195 (T.vaginalis)

89470.m00195

Species: T.vaginalis
Alias: TvagK0928, 89470.m00195
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
89470.m00195.AA Protein None 179 None Fasta, JSON
89470.m00195.kin_dom Protein Kinase Domain None 147 None Fasta, JSON

Protein domain

Protein domains of 89470.m00195.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 89470.m00195.AA Ciliate-E2 1-147 23 5.5e-33 110.56 In-house 170-365 (365) Show / Hide 
Range on Protein: 1-147
Range on HMM: 170-365/365
Sequence Identity: 23% (50 aa)

MSGISYLHHRG-IAHKEISLKNIRVLDDDTIKITEFGIYRRPVTSSGN-------------------------------------TFVYMPPEILQEKAF
.... ||| .. | |  | . || .     |||. ||. ..  ... |                                     |  ||.||||. |  
ILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKY

DK--------YKADIWTAGICLYAMTANHMPWTVNESTPVESIWEDIQSQICRGEIIFD------------------DNQSDILQDLLSQ----MLSIEP
|.        ||.||| .|..|| |  .  |.               | ||. ..| |.                  .. |.  .||...    ||  .|
DNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF---------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDP

DFRPD-ADEILNHAWL
. |.. ...|||| |.
EKRITGWEQILNHPWF
Kinase 89470.m00195.AA Ciliate-E2-Unclassified 2-147 25 2.1e-29 99.17 In-house 154-352 (352) Show / Hide 
Range on Protein: 2-147
Range on HMM: 154-352/352
Sequence Identity: 25% (52 aa)

SGISYLHHRG-IAHKEISLKNIRVLDDD----TIKITEFGIYRRP---------------------VTSSGNTFVYM----PPEILQEKAFDK---YKAD
.|..|||| . | |  | . || ..|..     |||. ||| ...                      ..   |  ||    .||.||..  |.   ||.|
QGLEYLHHKNNIIHRDIKPENI-LFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCD

IWTAGICLYAMTANHMPWTVNESTP-----VESIWE-----DIQSQICRGEI------------IFDDNQSDILQDLLSQMLSIEPDFRPDADEILNHAW
||. |..||.|  .  |   | ..       . |        ....|. ..|            . .... |...|||..||   |. |.....|||| |
IWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWI-NNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPW

L
.
F
Kinase 89470.m00195.AA CAMK 2-147 18 1.3e-23 72.35 In-house 190-425 (425) Show / Hide 
Range on Protein: 2-147
Range on HMM: 190-425/425
Sequence Identity: 18% (44 aa)

SGISYLHHRGIAHKEISLKNIRVLDDD-----------------TIKITEFGIYRR-----------------------------PVTSSGNTFVYMP-P
|.. |.| ..|.|  . . || . |..                 .|||. ||  ..                             . . .  |  ||. |
SAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAP

EILQE-------------KAFDKYKADIWTAGICLYAMTANHMPWTVN------ESTPVESIW-----EDIQSQICRGEIIFDDNQSDI-----------
|.|.              |  . .|.|.| .|. ||.|   ..|.         |    |  |     ...  .|..|.  |.. . ..           
EVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICE-D--E--WIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWD

-------------LQDLLSQMLSIEPDFRPDADEILNHAWL
              .||...||  .|. |. ....||| |.
DISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 89470.m00195.AA MARK 48-147 29 9.1e-21 64.77 In-house 168-262 (262) Show / Hide 
Range on Protein: 48-147
Range on HMM: 168-262/262
Sequence Identity: 29% (30 aa)

TFVYMPPEILQEKAFDKYKADIWTAGICLYAMTANHMPWTVNESTPVESI--WEDIQSQICRGEIIFDDNQSDILQDLLSQMLSIEPDFRPDADEILNHA
|  ||.|||.. |  | .|.|||. |. ||.|.  . |.        ..    .... .| ||.  . .. |. ...|....| . |. ||...||..| 
TPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFD-------GDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHP

WL
|.
WM
Kinase 89470.m00195.AA CAMKL 1-147 28 2.4e-20 61.5 In-house 137-297 (297) Show / Hide 
Range on Protein: 1-147
Range on HMM: 137-297/297
Sequence Identity: 28% (46 aa)

MSGISYLHHRGIAHKEISLKNIRVLDDD--TIKITEFGIY----------RRPVTSSGNTFVYMPPEILQE--KAFDKYKADIWTAGICLYAMTANHMPW
.|...|.| .||.|  | . || . ...  .|||. ||             .  . .  .  ||.|||.|   | .| .|.||| .|. ||||   ..|.
VSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPF

TVNEST--PVESIWEDIQSQICRGEII-FDDNQSDILQDLLSQMLSIEPDFRPDADEILNHAWL
         .. | .    ..|  . .      |  ..||...||   |. || ...|.|| |.
DDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 89470.m00195.AA Kin4 1-147 29 1.8e-17 49.62 In-house 120-273 (273) Show / Hide 
Range on Protein: 1-147
Range on HMM: 120-273/273
Sequence Identity: 29% (46 aa)

MSGISYLHHRGIAHKEISLKNIRVLDDDTIKITEFGIYRRPV-------TSSGNTFVYMPPEILQEKAFDKYKADIWTAGICLYAMTANHMPWTVNESTP
.||. |.| .|. |... | |. .  .. . ||.||     .       || |      |  ..  |...  |||||  |. |||| |  .||   .  |
ISGVHYMHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEFCEDNELMKTSCGSPCYAAPELVISTKPYEARKADIWSCGVILYAMLAGYLPWDDDHNNP

VESIWEDIQSQICRGEIIFDDNQSDILQDLLSQMLSIEPDFRPDADEILNHAWL
  .    .   | .  . | |    |  |||  ||  .|  |    .|  | ||
EGDDIARLYNYINQTPLKFPDYITPIPRDLLRRMLVPDPRRRINLQQIKRHEWL
Kinase 89470.m00195.AA ULK 48-147 25 8.9e-17 55.17 In-house 214-329 (329) Show / Hide 
Range on Protein: 48-147
Range on HMM: 214-329/329
Sequence Identity: 25% (30 aa)

TFVYMPPEILQ----EKAFDKYKADIWTAGICLYAMTANHMPWTVNESTPVE-SIWEDIQSQ-------ICRGEIIFD-----DNQSDILQDLLSQMLSI
|  || |.|||    .| .. ||.|||  |. .| |  .  |.  .  ..    | ..   .       |.   . |.     .. |. ..||...|| .
TPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQY

EPDFRPDADEILNHAWL
... | . .|..|| |.
DEKDRISWEELFNHPWF
Kinase 89470.m00195.AA ULK 48-147 28 7e-16 52.89 In-house 210-324 (324) Show / Hide 
Range on Protein: 48-147
Range on HMM: 210-324/324
Sequence Identity: 28% (33 aa)

TFVYMPPEILQ----EKAFDKYKADIWTAGICLYAMTANHMPWTVN-ESTPVESIWEDIQS------QICRGEIIFDDNQ-----SDILQDLLSQMLSIE
|  || |.|||    .| .. ||.|||  |. .| |  .  |.  . ...    | . |.       .|.   | |...      |. ..||...|| ..
TPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYD

PDFRPDADEILNHAWL
.. | . .||.|| |.
EKDRISWEEIFNHPWF
Kinase 89470.m00195.AA TKL 2-145 16 9.8e-14 45.84 In-house 143-364 (364) Show / Hide 
Range on Protein: 2-145
Range on HMM: 143-364/364
Sequence Identity: 16% (37 aa)

SGISYLHH--------RGIAHKEISLKNIRVLDDDT--------------IKITEFGIYRRP-------------------------VTSSGNTFVYMPP
.|..|||         ..|.|  .  ||| | .. |              .||. ||. |.                            . . |. .|.|
RGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAP

EILQEKAFDK---------------YKADIWTAGICLYAMTANHMPWT-VNESTPV-----ESIWEDIQSQICRGEIIF----------DDNQSDILQDL
|.|... ...                |.|..  ||.|. . .   |.   ......     | ... . .  .| .|             ..  . . .|
EVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKL

LSQMLSIEPDFRPDADEILNHA
. .  . .|. || ..||| . 
MQDCWDHDPEKRPSFQEILKRL
Kinase 89470.m00195.AA Pkinase 48-147 22 3.7e-12 44.08 Pfam 174-293 (293) Show / Hide 
Range on Protein: 48-147
Range on HMM: 174-293/293
Sequence Identity: 22% (28 aa)

TFVYMPPEILQEKAFDKYKADIWTAGICLYAMTANHMPWTVNE----------------STPVESIWEDI---------QSQICRGEIIFDDNQSDILQD
|  ||.||....   . .|.|.| .|. || |   . |.  ..                ..|... |.           . . .. .  | .|.|. ..|
TPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFP-GHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRH-W-HF-HWTF-HNWSEECKD

LLSQMLSIEPDFRPDADEILNHAWL
... .|   |  || |..||.| |.
FIKWCLCKDPKKRPTAEQILQHPWF
Kinase 89470.m00195.AA LKB 53-80 43 1.9e-08 21.23 In-house 174-203 (265) Show / Hide 
Range on Protein: 53-80
Range on HMM: 174-203/265
Sequence Identity: 43% (13 aa)

PPEILQE--KAFDKYKADIWTAGICLYAMT
|||. .     |. .|.||| .|. || ||
PPECANGNHDTFSGFKVDIWSMGVTLYNMT
Kinase 89470.m00195.AA LKB 120-147 32 2.7e-08 20.81 In-house 238-265 (265) Show / Hide 
Range on Protein: 120-147
Range on HMM: 238-265/265
Sequence Identity: 32% (9 aa)

LQDLLSQMLSIEPDFRPDADEILNHAWL
||.|.  ||..... |.   .| .| |.
LQNLIKGMLQYDHNKRFSCHQIMHHPWF
Kinase 89470.m00195.AA S_TKc 1-147 15 2e-06 -80.88 SMART 19-231 (231) Show / Hide 
Range on Protein: 1-147
Range on HMM: 19-231/231
Sequence Identity: 15% (38 aa)

MSGI-----------------------------------------------SY----LHHRGIAHKE------ISLKNIR--------------------
                                                   .     |...   ..       ..   .|                    
RHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIH

--------VLDDDTIKITEFGIYRRPVTSSGNTFVYMPPEILQEKAFDKYKADIWTAGICLYAMTANHMPWTVNESTPVESIWEDIQSQICRGEIIFDDN
         ||. .|||. ||. |.  |.   |  ||.||.|    ..| |.|.|  |..|| | .   |.       .. ... |              
RDLKPENILLDE-HIKICDFGLARQL-TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP-----QMQMMFKKIG-------------

QSDILQDLLSQMLSIEPDFRPDADEILN-------HAWL
 |. . |.....|  .|. || | |.|.       | |.
-SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 89470.m00195.AA LKB 3-37 40 0.002101 6.03 In-house 116-150 (265) Show / Hide 
Range on Protein: 3-37
Range on HMM: 116-150/265
Sequence Identity: 40% (14 aa)

GISYLHHRGIAHKEISLKNIRVLDDDTIKITEFGI
|  ||| ... || |   |. .  | |.||  ||.
GCEYLHSQRVVHKDIKPGNLLLTHDNTLKICDFGV
Kinase 89470.m00195.AA MARK 2-14 38 0.169105 0.86 In-house 115-127 (262) Show / Hide 
Range on Protein: 2-14
Range on HMM: 115-127/262
Sequence Identity: 38% (5 aa)

SGISYLHHRGIAH
|...|.| ..|.|
SAVNYCHSKNIVH