Gene 89650.m00231 (T.vaginalis)

89650.m00231

Species: T.vaginalis
Alias: 89650.m00231, TvagK0203
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
89650.m00231.AA Protein None 263 None Fasta, JSON
89650.m00231.kin_dom Protein Kinase Domain None 206 None Fasta, JSON

Protein domain

Protein domains of 89650.m00231.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 89650.m00231.AA CAMK 1-201 22 5.2e-52 165.5 In-house 79-420 (425) Show / Hide 
Range on Protein: 1-201
Range on HMM: 79-420/425
Sequence Identity: 22% (76 aa)

MSEVDCLME-------IDDPRIVRLYN-----------NYVF---------DNHIYMLM---EHCVG-----DLSKFLGKETPP------------KGI-
..|.....        .| | |..||            |  .         |.|.|| |   |.| |     ||  .. . ...            . . 
RREIEIMKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTND-YETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFT

--ELQSYIRGVITAVKACHDKNIAHCDLKPSNFLIDTY-----------------GRIKIGDFGLSTIFRD------------------------KPTAS
  | . |.| .. ||. ||..||.|.|||| | |.|.                  . ||| |||....|..                         .  .
EREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMK

CVKGTPMFMA-PEIFKP-------------YEYNPMKADIWAMGVTLYVIATGMLPFHGR-------------NIGEIVSKIENCDYN-IQLVEDN----
 . ||| .|| ||...               .| . |.|.|..|| ||.  .| .|| |              |. |.  || ...|. .    ..    
TFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCN

-------------------DLKILIAQCLDLDPECRPTPDQLL
                   . | || ..|  ||| |.| .| |
YGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCL
Kinase 89650.m00231.AA Pkinase 13-206 29 4.3e-48 170.88 Pfam 60-293 (293) Show / Hide 
Range on Protein: 13-206
Range on HMM: 60-293/293
Sequence Identity: 29% (69 aa)

PRIVRLYNNYVFDNHIYMLMEHCVG-----DLSKFLG--KETPP--KGIELQSYIRGVITAVKACHDKNIAHCDLKPSNFLIDTYGRI----KIGDFGLS
| |||||  .  ..|||| ||.| |     ||. ..   ....      |...|.. .. ... ||...| |.||||.|.|||  | |    ||.||||.
PNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLA

TI--FRDKPTASCVKGTPMFMAPEIFKPYEYNPMKADIWAMGVTLYVIATGMLPFHGR------NIGEIVSKIENCDYNIQLVED---------------
       .. .. . ||| .||||. . ..| . |.|.|..|..||  ..| .|| |.      .  ... .|  ...  .  ..               
KQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHW

------NDLKILIAQCLDLDPECRPTPDQLLIMNYF
       ..| .|  ||..||..|||..|.|   .|
TFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 89650.m00231.AA CAMKL 3-206 30 5.9e-43 134.83 In-house 62-297 (297) Show / Hide 
Range on Protein: 3-206
Range on HMM: 62-297/297
Sequence Identity: 30% (73 aa)

EVDCLMEID---DPRIVRLYNNYVFDNH------IYMLMEHCVGD---LSKFLGKETPPK-GIEL---QSYIRGVITAVKACHDKNIAHCDLKPSNFLID
|. ... ..    | |..||  .  ..|      ||. ||.| |    |  .. |.  ..  ..    . | | .. ||. ||...|.| |.|| | |.|
EIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLD

TYG--RIKIGDFGLSTIFRD-----KPTASCVKGTPMFMAPEIFKP--YEYNPMKADIWAMGVTLYVIATGMLPFHGR--------NIGEIVSKIENCDY
  |   ||| |||.|...|.       . .   |.| .||||||.    .|.  |.|||..||.||.. .| ||| .         || .   ||  . |
ENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-Y

NIQLVEDN-DLKILIAQCLDLDPECRPTPDQLLIMNYF
..    .  |.. || . |  .|| ||| .|..    .
YPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 89650.m00231.AA MARK 64-206 39 1.2e-42 137.33 In-house 116-262 (262) Show / Hide 
Range on Protein: 64-206
Range on HMM: 116-262/262
Sequence Identity: 39% (58 aa)

AVKACHDKNIAHCDLKPSNFLIDTYG--RIKIGDFGLSTIFRDKPTASCVKGTPMFMAPEIFKPYEYNPMKADIWAMGVTLYVIATGMLPFHGRN--IGE
||. ||.|||.|.|.|| | |||  |   ||| |||.|...      .   ||| .||||||.  .|.  |.|||..|| ||.. .| .|| | .  . |
AVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKE

IVSKIENCDYNIQLVEDNDLKILIAQCLDLDPECRPTPDQLLIMNYF
.  || ...| |      ... || . | ..|| ||| ....    .
LYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 89650.m00231.AA AGC 60-206 21 5.5e-42 105.15 In-house 160-395 (395) Show / Hide 
Range on Protein: 60-206
Range on HMM: 160-395/395
Sequence Identity: 21% (51 aa)

G-VITAVKACHD-KNIAHCD-LKPSNFLIDTYGRIKIGDFGLSTIFRDKP--------------------------------------------------
| .. |.   |. ..| | | ||| | |.|  | ||. ||||........                                                  
GCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKR

-TASCVKG--TPMFMAPEIFKPYEYNPMKADIWA--MGVTLYVIATGMLPFHGRNIG----------EIVSKIENCD----YNIQLVED-----------
 ...   |  || .|||||.    |..  .|.|.  .|. .|   ||  ||.| | .          |.  ||.|..     ....  .           
DRTWTFCGPCTPEYMAPEIL----YGKA-CDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWF

-NDLKILIAQCLDLDPECRPT----------PDQLLIMNYF
 ...| || ..|  ||| |..           ...    .|
SPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 89650.m00231.AA Ciliate-E2 7-206 23 3.6e-41 139.06 In-house 86-365 (365) Show / Hide 
Range on Protein: 7-206
Range on HMM: 86-365/365
Sequence Identity: 23% (70 aa)

LMEIDDPRIVRLYNNYV--FDNHIYMLMEHCVG-DLSKFLG--KETPPKG---------IELQSYIRGVIT---------------AVKACHDKN-IAHC
| ... | |...|  .    ||.||. || | | || ...   |   ..           | . ... ..                |.. .| || | | 
LEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHR

DLKPSNFLIDTYGRIKIGDFGLSTIFRDKPTASC--------------------------------VKGTPMFMAPEIFK--PYE------YNPMKADIW
|.||.| |.     ||| |||||... |.                                     . |||..|||||..  .|.      .   |.|||
DIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIW

AMGVTLYVIATGMLPFHGRNIGEIVSKIENCDYNIQ------------------LVEDNDLKILIAQ----CLDLDPECRPT-PDQLLIMNYF
..||.||   .| .||          .|..|.....                  .  ... | || .    .|. ||| |.| ..|.|   .|
SLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 89650.m00231.AA S_TKc 1-206 26 1.4e-38 135.36 SMART 1-231 (231) Show / Hide 
Range on Protein: 1-206
Range on HMM: 1-231/231
Sequence Identity: 26% (68 aa)

M------------------------------------SEVDCLMEIDDPRIVRLYNNYVFDNHIYMLMEHCVG---DLSKFLGKETPP------KGIELQ
                                     .|...|.. . | ||.||  ..  .|.|| ||.| |   || ... |  ..         . .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HAR

SYIRGVITAVKACHDKNIAHCDLKPSNFLIDTYGRIKIGDFGLSTIFRDKPTASCVKGTPMFMAPEIFKPYEYNPMKADIWAMGVTLYVIATGMLPFHGR
.|.. .. |.. ||...| |.||||.| |.|.  .|||.||||....      . . ||| .||||..    |.. |.|.|. |..||  ..|  ||.  
FYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--

NIGEIVSKIENCDYNIQLVEDNDLKILIAQCLDLDPECRPTPDQLLI-------MNYF
.. ..  ||           . ..| .| .||. ||| |||  ..|        . .|
QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 89650.m00231.AA ULK 15-206 24 1.7e-35 123.47 In-house 77-324 (324) Show / Hide 
Range on Protein: 15-206
Range on HMM: 77-324/324
Sequence Identity: 24% (62 aa)

IVRLYNNYVFD--NHIYMLMEHCVG-DLSKFLGKETP------PKGIE---LQSYIRGVITAVKACHDKNIAHCDLKPSNFLIDTY------------GR
||.||  .  .  |.||. || | | ||.... |  .      .| ..    .....  . . |. |..|| |.|.||.| ||               |.
IVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGV

IKIGDFGLSTIFRD-----KPTASCV-----KGTPMFMAPEIFK----PYEYNPMKADIWAMGVTLYVIATGMLPFHGRNIGEIV----SKIEN------
.||.|||.. .. .       . .||     ||||..|||.|..      .|.  |.||| .|. .| . .|  || .. . . .    . |.|      
LKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQI

CDYNIQLVED---------NDLKILIAQCLDLDPECRPTPDQLLIMNYF
  .| ..  .         ...| || ..|  |.. | . .... .  |
YIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 89650.m00231.AA ULK 1-206 23 1.3e-34 118.27 In-house 58-329 (329) Show / Hide 
Range on Protein: 1-206
Range on HMM: 58-329/329
Sequence Identity: 23% (64 aa)

MSEVDCLMEIDDPR--------IVRLYNNYVFD--NHIYMLMEHCVG-DLSKFLGKETP-------PKGIE---LQSYIRGVITAVKACHDKNIAHCDLK
..|.. . ....|         ||.||  .  .  |.||. || | | ||.... |  .       .| ..    .....  . . |. |..|| |.|.|
KNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIK

PSNFLIDTY------------GRIKIGDFGLSTIFRDK-----PTASCV-----KGTPMFMAPEIFK----PYEYNPMKADIWAMGVTLYVIATGMLPFH
|.| ||.              |..||.|||..  . .       . .||     .|||..|||.|..      .|.  |.||| .|. .| . .|  || 
PQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFY

GRNIGEIV-----SKIEN--------CDYNIQ-------LVEDNDLKILIAQCLDLDPECRPTPDQLLIMNYF
.  . . .     . |.|        .. ..|        .  ...| || ..|  |.. | . ..|. .  |
AW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 89650.m00231.AA Ciliate-E2-Unclassified 7-206 22 8.5e-34 114.62 In-house 70-352 (352) Show / Hide 
Range on Protein: 7-206
Range on HMM: 70-352/352
Sequence Identity: 22% (64 aa)

LME---IDDPRIVRLYNNYVF--DNHIYMLMEHCVG-DLSKFLGKETP-----------------PKGIELQ-----SYIRGVITAVKACHDKN-IAHCD
.|    .. | .....  |.|  ...||. || | | ||.... |                        . .      |.. .. . . .| || | | |
IMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRD

LKPSNFLIDTYG---RIKIGDFGLST-----------------IFRDKPTASCVKGTPMFM----APEIFKPYEYNPM---KADIWAMGVTLYVIATGML
.||.| |.|  |   .||| |||.|                  |.... . ... |||..|    |||...  .|. .   |.|||..|| || . .| .
IKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFC-GTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYY

PFHGRNIGE----------------IVSKIENCDYNIQLVE--------DNDLKILIA----QCLDLDPECRPTPDQLLIMNYF
|| ..|  .                . ..| .......  .        ..  | .|     ..|. .|. |.|..|.|   .|
PFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 89650.m00231.AA NEK 1-206 29 3.1e-33 114.59 In-house 51-286 (286) Show / Hide 
Range on Protein: 1-206
Range on HMM: 51-286/286
Sequence Identity: 29% (72 aa)

M-SEVDCLMEIDDPRIVRLYNNYVFDN--HIYMLMEHCV--GDLSKFLGKETPPKGIELQS----YIRG-VIT--------AVKACHDK-----NIAHCD
. .||  | ... | ||. |. .. ..  ...  ||.|   |||.... .      |. |     |.   .|         |.| .||.     .| | |
QNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS------IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRD

LKPSNFLIDTYGR----IKIGDFGLSTIFRDKPT-ASC-VKGTPMFMAPEIFKPYEYNPMKADIWAMGVTLYVIATG--MLPFHGR--NIGEIVSKIENC
.||.|  ..  ..    .||||||.| .. .. . |.  . ||| .|.||...   ||  |.|||. |. || ..|     || .   |. . . || ..
IKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNKPYN-NKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKG

-DYN-IQLV--EDNDLKILIAQCLDLDPECRPTPDQLLIMNYF
 .|. |.      .||. || |.|  ||| ||. .|.| | . 
PQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase 89650.m00231.AA QIK 61-157 45 9.6e-28 98.49 In-house 127-223 (272) Show / Hide 
Range on Protein: 61-157
Range on HMM: 127-223/272
Sequence Identity: 45% (44 aa)

VITAVKACHDKNIAHCDLKPSNFLIDTYGRIKIGDFGLSTIFRDKPTASCVKGTPMFMAPEIFKPYEYNPMKADIWAMGVTLYVIATGMLPFHGRNI
...||. ||..||.| |||  | |.|    ||| |||.|  |    . .   |.| . |||.|.  ||. .|.||| ||| |||  .| ||| | ..
ICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVDIWSMGVVLYVLVCGALPFDGKTL
Kinase 89650.m00231.AA TyrKc 1-206 20 7.8e-10 -63.63 SMART 1-280 (280) Show / Hide 
Range on Protein: 1-206
Range on HMM: 1-280/280
Sequence Identity: 20% (59 aa)

M-------------------------------------SEVDCLMEI--DDPRIVRLYNNYVFD-------NHIYMLMEHCV-GDLSKFLGKETP-PKGI
                                      .|   ....  . | |||||   . .         ....||..  ||| ..| |  |  .  
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

ELQSYIRGVITAVKACHDKNIAHCDLKPSNFLIDTYGRIKIGDFGLS-TIFRD---------KPTAS--CVKG-TPMF-MAPEIFKPYEYNPMKADIWAM
.| |.   .       |.||. | ||   | |..  ...||.|||||  |  |         . ...  . |.  |   |||| .. ..... | |.|. 
DLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT-KSDVWSF

GVTLY-VIATGMLPFHG-----RNIGEIVSKIENCDYNIQLVE---------DNDLKILIAQCLDLDPECRPTPDQLLIMNYF
||... .   |. |  |      .  |.. .... ..  |  .           ..  .. || . |||.|||  ..    .|
GVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 89650.m00231.AA QIK 3-35 30 0.18294 1.98 In-house 48-80 (272) Show / Hide 
Range on Protein: 3-35
Range on HMM: 48-80/272
Sequence Identity: 30% (10 aa)

EVDCLMEIDDPRIVRLYNNYVFDNHIYMLMEHC
||  .  .. | |..||.    |. .|...| |
EVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYC