Gene 80892.m00189 (T.vaginalis)

80892.m00189

Species: T.vaginalis
Alias: 80892.m00189, TvagK0006
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
80892.m00189.AA Protein None 183 None Fasta, JSON
80892.m00189.kin_dom Protein Kinase Domain None 167 None Fasta, JSON

Protein domain

Protein domains of 80892.m00189.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 80892.m00189.AA CAMK 1-167 23 3.3e-53 169.42 In-house 85-367 (425) Show / Hide 
Range on Protein: 1-167
Range on HMM: 85-367/425
Sequence Identity: 23% (68 aa)

MRN-------ANNPYILKIYEVVED-------------------QKYIYIVE---EYVSHG----NLLDYFNKR---------------NTISYSLIKKF
|..        . | |.|.||| ||                   .|..|.|    ||.| |     |.||  ..                 .. .  ...
MKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRY

VSQIIYATKYLNEVLHVTHRDLKLENILLDEYE-----------------NIKIIDFGLSSIHRH------------------------RVKMHKLCGTP
. ||. | .|. .   . |||||.||||||. .                 ||||||||.. . ..                          ||.  ||||
FRQICSAVHYCHSHN-IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTP

EYIA-PEVIQNSS--------------YTDNIDTWSIGIILYAMTHRCLPFDGK-------------TTQEIFTNVVRCDPQYD
||.| |||.. ..              |.  .| ||.|.|||.|   ..||.|.             . .|.| .. ... ...
EYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFP
Kinase 80892.m00189.AA NuaK 1-150 41 5.4e-52 134.68 In-house 53-202 (252) Show / Hide 
Range on Protein: 1-150
Range on HMM: 53-202/252
Sequence Identity: 41% (63 aa)

MRNANNPYILKIYEVVEDQKYIYIVEEYVSHGNLLDYFNKRNTISYSLIKKFVSQIIYATKYLNEVLHVTHRDLKLENILLDEYENIKIIDFGLSSIHRH
|   | | | .|||| | .  | || || | |.| ||  ... ..   ...|  ||. |  |      . ||||||||||||.  |.|| |||||..   
MSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPEREARHFFRQIVSAVHYCHKH-RICHRDLKLENILLDQNCNAKIADFGLSNYYHD

RVKMHKLCGTPEYIAPEVIQNSSYTD-NIDTWSIGIILYAMTHRCLPFDGK
   .|  || | |  ||..    |.   .| || |..||.| .  .||||.
QKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFDGH
Kinase 80892.m00189.AA CAMKL 1-151 39 2.2e-50 158.94 In-house 66-240 (297) Show / Hide 
Range on Protein: 1-151
Range on HMM: 66-240/297
Sequence Identity: 39% (69 aa)

MRNAN---NPYILKIYEVVEDQKY------IYIVEEYVSHGN--LLDYFNKR----NTISYSLIKKFVSQIIYATKYLNEVLHVTHRDLKLENILLDEYE
|.  |    | | |.|||.|....      ||.| ||.| |.  |.||  |.      .. .  ...  ||. | .|. . ... |||.|.|||||||  
MKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHS-HGIVHRDIKPENILLDENG

--NIKIIDFGLSSIHR-H----RVKMHKLCGTPEYIAPEVIQN--SSYT-DNIDTWSIGIILYAMTHRCLPFDGKT
  ||||||||.| ..| .      |..  ||.|.| |||..|    .|    .| ||.|.|||||    ||||. |
NNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDT
Kinase 80892.m00189.AA AGC 1-169 20 1.4e-47 119.95 In-house 74-343 (395) Show / Hide 
Range on Protein: 1-169
Range on HMM: 74-343/395
Sequence Identity: 20% (56 aa)

MRNAN----------NPYILK-IYEVVEDQKY--IYIVEEYVS--------HGN--LLDYFN---KRNTISYSLIKKFVSQ-------IIYATKYLNEVL
. ..|          .|.| |  .   .|...  .|.| ||..         |   |. .     |. . . . .. . ..       |. |  || . .
LEKCNHTHNHPIKSHHPFIVKILHYSFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHM

HVTHRD-LKLENILLDEYENIKIIDFGLSSIHRHR---------------------------------------------------VKMHKLCG--TPEY
.. ||| ||.|||||||  .||. ||||. . . .                                                   .. . .||  ||||
GIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEY

IAPEVIQNSSYTDNIDTWS--IGIILYAMTHRCLPFDGKTTQ----------EIFTNVV------RCDPQYDND
.|||..    |.   | ||   |...| |   . || |...|          |.| ..        ........
MAPEIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFP
Kinase 80892.m00189.AA Ciliate-E2a 1-162 35 1.3e-46 135.2 In-house 53-231 (275) Show / Hide 
Range on Protein: 1-162
Range on HMM: 53-231/275
Sequence Identity: 35% (64 aa)

MRNANNPYILKIYEVVEDQKYIYIVEEYVSHGNLLDYFNKRNTISYS--LIKKFVSQIIY-ATKYLNEVLHVTHRDLKLENILLD-------EYENIKII
||. ..| |.|.||| || ...|.| ||.. | |.|....  .. .    |...  |... .  |.   ... |||||.||||..       .  .||||
MRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEIQEICDIMQQLLWQGLHYMHQ-RNIMHRDLKPENILFKNCSKNSIQNSDIKII

DFGLSSIHRHRVK--MHKLCGTPEYIAPEVIQNSS------YTDNIDTWSIGIILYAMTHRCLPFDGKTTQEIFTNVVRC
||||.       |  |.. |||| |.||||. |        |.   | ||.|.|.| .   ..||.|||..||. .. .|
DFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDMWSCGVIFYILLCGKPPFKGKTYNEILQQNKKC
Kinase 80892.m00189.AA AMPK 7-165 39 1.1e-45 133.62 In-house 59-218 (254) Show / Hide 
Range on Protein: 7-165
Range on HMM: 59-218/254
Sequence Identity: 39% (64 aa)

PYILKIYEVV-EDQKYIYIVEEYVSHGNLLDYFNKRNTISYSLIKKFVSQIIYATKYLNEVLHVTHRDLKLENILLDEYENIKIIDFGLSSIHRHRVKMH
| | . |||. | .. |..| |||| | | ||  |.. ..    ..|  ||| .  |. . . . |||||.||.|||.  |||| ||||| .     .  
PHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQEREACRFFQQIISGVEYCHR-HMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLK

KLCGTPEYIAPEVIQNSSYT-DNIDTWSIGIILYAMTHRCLPFDGKTTQEIFTNVVRCDPQ
  || | | |||.|..  |    .|.|| |.|||||  . ||||   | . . ... ....
TACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPFDDENTPTLYKKIKNGEYY
Kinase 80892.m00189.AA Pkinase 7-169 32 3.1e-44 157.5 Pfam 60-240 (293) Show / Hide 
Range on Protein: 7-169
Range on HMM: 60-240/293
Sequence Identity: 32% (60 aa)

PYILKIYEVVEDQKYIYIVEEYVSHG----NLLDYFN--KRNTI--SYSLIKKFVSQIIYATKYLNEVLHVTHRDLKLENILLDEYENI----KIIDFGL
|.|...|...|| ..||.| ||. .|     | ||    .....  |.  .|... ||. . .|. .   . |||||.||||.|.  .|    ||.||||
PNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGL

SSI--HRHRVKMHKLCGTPEYIAPEVIQ-NSSYTDNIDTWSIGIILYAMTHRCLPFDGK------TTQEIFTNVVRCDPQYDND
.    . . . |. .||||.|.|||||. .. |.  .| ||.|.||| |  . .||.|.      . .... .. .... .| .
AKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWP
Kinase 80892.m00189.AA MARK 7-166 35 1.3e-43 140.54 In-house 59-227 (262) Show / Hide 
Range on Protein: 7-166
Range on HMM: 59-227/262
Sequence Identity: 35% (61 aa)

PYILKIYEVVE--DQKY-IYIVEEYVSHGNLLDYFNKR--NTISYSLIKKFVSQIIYATKYLNEVLHVTHRDLKLENILLDEYE--NIKIIDFGLSSIHR
|.| | ..|.|  . .  ||.. ||.| |.|.||  ..    .. .. ... .||..| .|. .   . |||.|.||||.||    ||||||||.| .  
PNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGRLHEEEARRIFRQIVSAVNYCHSKN-IVHRDIKPENILIDENGNHNIKIIDFGFSICIP

HRVKMHKLCGTPEYIAPEVIQNSSYT-DNIDTWSIGIILYAMTHRCLPFDGKT--TQEIFTNVVRCDPQY
   |    ||||.| |||...   |.   .|.|| |..||.|.. ..||||.|    |.. ...|.....
PGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDI
Kinase 80892.m00189.AA Ciliate-E2 1-168 26 1.7e-42 143.67 In-house 86-309 (365) Show / Hide 
Range on Protein: 1-168
Range on HMM: 86-309/365
Sequence Identity: 26% (62 aa)

MRNANNPYILKIYEVVE--DQKYIYIVEEYVSHGNLLDYFNKRNTIS-----------YSLIKKFVSQIIY---------------ATKYLNEVLHVTHR
... |.|.|.|.||. .  |...||.| ||...|.|.|| ..... .              ||..  ||..               | .|| .  .. ||
LEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHR

DLKLENILLDEYENIKIIDFGLSSI-------HRHRVKMHK--------------------------LCGTPEYIAPEVIQNSS---------YTDNIDT
|.|.||||.     ||||||||| .       ..|  ...|                          .||||.| |||.... .         |.  .| 
DIKPENILF-----IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDI

WSIGIILYAMTHRCLPFDGKTTQEIFTNVVRCDPQYDN
||.|.||| |    .||        . .   |. ....
WSLGVILYEMLFGKPPF--------QQQIKQCKIDFPC
Kinase 80892.m00189.AA Ciliate-E2-Unclassified 1-151 30 4e-40 136.88 In-house 75-274 (352) Show / Hide 
Range on Protein: 1-151
Range on HMM: 75-274/352
Sequence Identity: 30% (60 aa)

MRNANNPYILKIYEVVEDQKYIYIVEEYVSHGNLLDYFNKRNT-----------------ISYSLIK-----KFVSQIIYATKYLNEVLHVTHRDLKLEN
..| ..|.|.| ... .|...|||| ||. .|.|..| .||..                 ..   .|     ..  ||. . .|| . ... |||.|.||
LLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPEN

ILLDEYE---NIKIIDFGLSSIHRHRVK----------------MHKLCGTPEYI----APEVIQNSSYTDN----IDTWSIGIILYAMTHRCLPFDGKT
||.|.     .|||||||.|.     ..                |.  ||||.|.    ||||.|.  | .     .| || |.|||.|    .||....
ILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNN
Kinase 80892.m00189.AA QIK 7-154 36 7.6e-36 125.41 In-house 58-225 (272) Show / Hide 
Range on Protein: 7-154
Range on HMM: 58-225/272
Sequence Identity: 36% (61 aa)

PYILKIYEVVEDQKYIYIVEEYVSHGNLLDYFNKRNT--------------------ISYSLIKKFVSQIIYATKYLNEVLHVTHRDLKLENILLDEYEN
|.| | |.| | ....||| || | | . || .|                       .. .  ..  .||. | .|. . ... ||||| ||||||.  |
PHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKMVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHK-RNIVHRDLKAENILLDNNMN

IKIIDFGLSSIHRHRVKMHKLCGTPEYIAPEVIQNSSYT-DNIDTWSIGIILYAMTHRCLPFDGKTTQE
|||.|||.|        .   ||.| | |||. .  .|.   .| ||.|..||..    ||||||| |.
IKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVDIWSMGVVLYVLVCGALPFDGKTLQN
Kinase 80892.m00189.AA S_TKc 1-181 27 2.1e-21 78.38 SMART 18-220 (231) Show / Hide 
Range on Protein: 1-181
Range on HMM: 18-220/231
Sequence Identity: 27% (63 aa)

MRNAN------------------------NPYILKIYEVVEDQKYIYIVEEYVSH--GNLLDYFNKRNT------ISYSLIKKFVSQIIYATKYLNEVLH
 |. .                         |.| |.|.| .| ...|.| ||...  |.|.||  ||..      ..   ..... ||. | .|. .  .
CRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-G

VTHRDLKLENILLDEYENIKIIDFGLSSIHRHRVKMHKLCGTPEYIAPEVIQNSSYTD-NIDTWSIGIILYAMTHRCLPFDGKTTQEIFTNVVRCDPQYD
. ||||| |||||||  .|||.||||. .       . .||||.|.||||.   .|.   .| ||.|.||| |  .. ||.  . |..| ...       
IIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-------

NDIPAGLLKTHLR------------E
 .    ...  |.            .
SPEAKDFIRKCLQKDPEKRPTAEALQ
Kinase 80892.m00189.AA TyrKc 1-179 19 5.9e-09 -77.81 SMART 1-280 (280) Show / Hide 
Range on Protein: 1-179
Range on HMM: 1-280/280
Sequence Identity: 19% (55 aa)

M-------------------------------------------RNA--NNPYILKIYEVVEDQ-------KYIYIVEEYVSHGNLLDYF-NKRNTISYS
                                            ..   ..| |...| |. .|       . ..|| ||..||.|.||  ..|.... .
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

LIKKFVSQIIYATKYLNEVLHVTHRDLKLENILLDEYENIKIIDFGLSSIHRHR--------VKMHKL--CGTP----EYIAPEVIQNSSYTDNIDTWSI
   .|  ||     || .  .. ||||   |.|..|   .|| |||||  . .         ....|   .|         |||.|. . .|   | || 
DLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSF

GIILYAMTHRC-LPFDG-----KTTQEIFTNVVRC--DPQYDND-------IPAGL--------------------LKTHL
|. .. .  ..  |  |     .. ||.. .| .    || .||        |. .                    ..  .
GVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 80892.m00189.AA Pkinase_Tyr 1-95 33 1e-08 30.17 Pfam 57-158 (270) Show / Hide 
Range on Protein: 1-95
Range on HMM: 57-158/270
Sequence Identity: 33% (35 aa)

MRNA-NNPYILKIYEVVE-DQKY--IYIVEEYVSHGNLLDYFNK----RNTISYSLIKKFVSQIIYATKYLNEVLHVTHRDLKLENILLDEYENIKIIDF
|..  ..| |.. | |.  ...   |||| ||. ||.||||  |    .. .. . . ..  ||  .  || .  .  ||||   |.|..|   .|| ||
MKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESK-NCIHRDLAARNCLVTENNVVKICDF

GLS
||.
GLA