Gene 82761.m00587 (T.vaginalis)

82761.m00587

Species: T.vaginalis
Alias: 82761.m00587, TvagK0373
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
82761.m00587.AA Protein None 147 None Fasta, JSON
82761.m00587.kin_dom Protein Kinase Domain None 82 None Fasta, JSON

Protein domain

Protein domains of 82761.m00587.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 82761.m00587.AA AGC 5-82 30 1.6e-36 90.66 In-house 280-395 (395) Show / Hide 
Range on Protein: 5-82
Range on HMM: 280-395/395
Sequence Identity: 30% (35 aa)

YSYAIDEWA--LGVLAFEMILGVTPFYDDN----------KAVMFGKIV------NEPPVFP----------QGLDNRIIDFINKLLAKDPAQRAK----
|..| | |.  ||.| .||. | .|||.||          .. || ||       |... ||          . ...   |.|.||| |||..|      
YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGN

------FDDLKSHPFF
      ....|.||.|
DFGDKGAEEIKNHPWF
Kinase 82761.m00587.AA Aur 3-82 31 5.2e-25 62.47 In-house 176-257 (257) Show / Hide 
Range on Protein: 3-82
Range on HMM: 176-257/257
Sequence Identity: 31% (26 aa)

QPYSYAIDEWALGVLAFEMILGVTPFYD-DNKAVMFGKIV-NEPPVFPQGLDNRIIDFINKLLAKDPAQRAKFDDLKSHPFF
|.. . .| |.||||..|.. |  ||.  .|.  .. .|  .   .||  .     |.|.|.| .|| ||   |. ..||..
QMHDHKVDIWCLGVLCYELCHGCPPFESNENHDETYDRIKNKVDIQFPSHISKEAKDLISKILQHDPKQRMTLDQIMNHPWI
Kinase 82761.m00587.AA SGK 3-82 41 9.7e-25 72.93 In-house 200-283 (283) Show / Hide 
Range on Protein: 3-82
Range on HMM: 200-283/283
Sequence Identity: 41% (35 aa)

QPYSYAIDEWALGVLAFEMILGVTPFYDDNKAVMFGKIVNEPPVFPQGLDNRIIDFINKLLAKDPAQR--AK--FDDLKSHPFF
||.. . | | || . .||. |  |||. ||. |. .| |.|  .|..  |   | |. ||.||| .|  .|  | . |.||||
QPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 82761.m00587.AA Akt 12-82 36 3.6e-24 74.08 In-house 186-264 (264) Show / Hide 
Range on Protein: 12-82
Range on HMM: 186-264/264
Sequence Identity: 36% (29 aa)

WA-LGVLAFEMILGVTPFYDDNKAVMFGKIVNEPPVFP--QGLDNRIIDFINKLLAKDPAQRA--KFD---DLKSHPFF
|. ||.. .||. |  |||.... .|| || |.|  ||    ...   |.|..|| ||| .|   ...   ..|.||.|
WGSLGCVMYEMMCGRPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 82761.m00587.AA AktR 1-82 31 1.2e-23 84.87 In-house 177-268 (268) Show / Hide 
Range on Protein: 1-82
Range on HMM: 177-268/268
Sequence Identity: 31% (29 aa)

MQ-QPYSYAIDEWALGVLAFEMILGVTPFYDDNKAVMFGKIVNEP---PVFPQGLDNRIIDFIN-KLLAKDPAQRAK-----FDDLKSHPFF
.. ... ...| ||.|.. .||. | .|||..|.  || || ...   . .|  . .   |.|. ||| |.| .| .     ....||||.|
TKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 82761.m00587.AA Ciliate-E2-Unclassified 1-82 28 2.2e-22 74.47 In-house 239-352 (352) Show / Hide 
Range on Protein: 1-82
Range on HMM: 239-352/352
Sequence Identity: 28% (32 aa)

MQQPYS----YAIDEWALGVLAFEMILGVTPFYDDNKAV----------------MFGKIVNEPPVFP--------QGLDNRIIDFIN----KLLAKDPA
..| |.    |..| |.|||...||. |  |||| |.                  .. .| . .. ||        .....  .||||    |.| |.| 
QGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPN

QRAKFDDLKSHPFF
.|  |.... ||.|
KRITFEQILNHPWF
Kinase 82761.m00587.AA Ciliate-E2 2-82 25 8.5e-21 68.11 In-house 270-365 (365) Show / Hide 
Range on Protein: 2-82
Range on HMM: 270-365/365
Sequence Identity: 25% (27 aa)

QQPYSYAIDEWALGVLAFEMILGVTPFYDDNKAVMFGKIVNEPPVFP------------------QGLDNRIIDFINK----LLAKDPAQRAK-FDDLKS
|..|.|..| |.|||. .||. | .||        . .| . .  ||                  . ...  .|.|.|    .| ||| .|   ..... 
QKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN

HPFF
||.|
HPWF
Kinase 82761.m00587.AA PKC 3-82 29 2.6e-19 59.08 In-house 175-262 (262) Show / Hide 
Range on Protein: 3-82
Range on HMM: 175-262/262
Sequence Identity: 29% (26 aa)

QPYSYAIDEWALGVLAFEMILGVTPFYDDNKAVMFGKIVNEPPVFPQGLDNRIIDFINKLLAKDPAQR-----AK---FDDLKSHPFF
|.|. ..| ||.||| .|| .|  ||  ..   .|  | .. |..|  |  .. . . ... |.|..|     ..   ..| ..||||
QEYGKSVDWWAFGVLMYEMMAGQSPFHGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase 82761.m00587.AA RSK 2-82 31 2.8e-19 67.41 In-house 185-278 (278) Show / Hide 
Range on Protein: 2-82
Range on HMM: 185-278/278
Sequence Identity: 31% (30 aa)

QQP-YSYAIDEWALGVLAFEMILGVTPFYD---DNKAVMFGKIVNEP--PVFP--QGLDNRIIDFINKLLAKDPAQRAK-----FDDLKSHPFF
||  .. | | | |||| .||  | .||.    .|... . .| .    . .|  | | .   |.|.|.| .||..| .      ...|.||.|
QQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 82761.m00587.AA PKA 8-82 36 5.4e-19 69.43 In-house 179-263 (263) Show / Hide 
Range on Protein: 8-82
Range on HMM: 179-263/263
Sequence Identity: 36% (31 aa)

AIDEWALGVLAFEMILGVTPFYDD--NKAVMFGKIVNEPPVFPQGLDNRI---IDFINKLLAKDPAQRA---KF--DDLKSHPFF
..| ||||.| .||  |..||||.  ... .. ||.|    ||. .|..     |.|.|||..|. .|    |.  .| | |..|
SVDWWALGILIYEMLAGYPPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 82761.m00587.AA Pkinase 2-82 23 7.3e-18 64.25 Pfam 186-293 (293) Show / Hide 
Range on Protein: 2-82
Range on HMM: 186-293/293
Sequence Identity: 23% (25 aa)

QQPYSYAIDEWALGVLAFEMILGVTPFYDD------NKAVMFGKIVNEPPVFPQGLD---------------------NRIIDFINKLLAKDPAQRAKFD
.|.|....| |..|.. .||..| .||...      .. .|. .|   |. |.   .                        .|||...|.|||..|  ..
GQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAE

DLKSHPFF
... ||.|
QILQHPWF
Kinase 82761.m00587.AA S_TK_X 83-143 30 1.5e-13 52.24 SMART 1-79 (79) Show / Hide 
Range on Protein: 83-143
Range on HMM: 1-79/79
Sequence Identity: 30% (24 aa)

EGFDWVKVYN--RDYTPSFVPQVK----DPLNTQNFDPEFTSEIAADSFVQPAIGDDGA------------VQGFSYYD
 |.|| |.||  . ..| |.|..|    .|  | |||||||.| . .. ..|.. .                 ||.|  
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase 82761.m00587.AA Pkinase_C 102-145 40 5.4e-08 31.45 Pfam 1-46 (46) Show / Hide 
Range on Protein: 102-145
Range on HMM: 1-46/46
Sequence Identity: 40% (19 aa)

QVKDPLNTQNFDPEFTSEIAADSF---VQPAIGDDGAVQGFSYYDSN
|||.|. |.|||||||.| . |..        ||. . .||.|  ..
QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFTYVNPD