Gene 96280.m00182 (T.vaginalis)

96280.m00182

Species: T.vaginalis
Alias: 96280.m00182, TvagK0256
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
96280.m00182.AA Protein None 237 None Fasta, JSON
96280.m00182.kin_dom Protein Kinase Domain None 177 None Fasta, JSON

Protein domain

Protein domains of 96280.m00182.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 96280.m00182.AA CAMK 1-177 21 5.6e-48 152.28 In-house 134-425 (425) Show / Hide 
Range on Protein: 1-177
Range on HMM: 134-425/425
Sequence Identity: 21% (62 aa)

MLM---EYCPN-----DLFNLLKGNTN---------------VTEDQMLRYMHDILIAIKACHDRNIAHNDIKPSNFLLDKY-----------------G
| |   |||..     |||. .. ...               .||..  ||.. |. |.. ||..||.| |.|| | |||.                  .
MVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNN

RIKMCDFGLSRMYDE------------------------HCMSSCYRGTMLFMA-PELFKK-------------SPYNPLKADIWSIGITFFYIATRSFP
 || .|||.....|.                          . . . ||  .|| ||....              || . |.|.||.|.  .   .  .|
NIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPP

FFAA--------------DKQVYIKSLNSGIY-PQFIVQN----------------------PQLRVLIQSCLQVNPEARPTIDELLQMPYF
| .               |.. . | ..   . | . . .                      .. . ||...|||.|| |.||.. |. | .
FYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Pkinase 96280.m00182.AA Pkinase 1-177 26 1.1e-46 166.14 Pfam 77-293 (293) Show / Hide 
Range on Protein: 1-177
Range on HMM: 77-293/293
Sequence Identity: 26% (59 aa)

MLMEYCPN-----DLFNLLK--GNTNV--TEDQMLRYMHDILIAIKACHDRNIAHNDIKPSNFLLDKYGRI----KMCDFGLSRM--YDEHCMSSCYRGT
| ||||..     ||| ...   ....  .|..  .||  || ... ||...| | |.||.|.|.|. | |    | |||||..   |      . . ||
MVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGT

MLFMAPELFKKSPYNPLKADIWSIGITFFYIATRSFPFFAA------DKQVYIKSLNSGIYPQFIVQN---------------------PQLRVLIQSCL
  .||||. ....| . |.|.||.|..... ... .||  .      |... |.   .....  . .                      . .. .| .||
PWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCL

QVNPEARPTIDELLQMPYF
...|. |||....|| |.|
CKDPKKRPTAEQILQHPWF
Kinase 96280.m00182.AA CAMKL 1-177 32 4.3e-45 141.75 In-house 98-297 (297) Show / Hide 
Range on Protein: 1-177
Range on HMM: 98-297/297
Sequence Identity: 32% (66 aa)

MLMEYCPND---LFNLL--KGNTN--VTEDQMLRYMHDILIAIKACHDRNIAHNDIKPSNFLLDKYG--RIKMCDFGLSRMYDE-----HCMSSCYRGTM
. ||||..    ||. .  .|. .   .|..  ||   |. |.. ||...|.| |||| | |||. |   || .|||.| ||..       . .   |. 
LVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSP

LFMAPELFKK--SPYNPLKADIWSIGITFFYIATRSFPFFAA--------DKQVYIKSLNSGIYPQFIVQNP-QLRVLIQSCLQVNPEARPTIDELLQMP
 .||||.|..   ||.  |.||||.|.. . . .  .|| ..        ..  . .  ..| |   |   . ..| ||.. |||||| ||||..... |
PYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNHP

YF
 .
WM
Kinase 96280.m00182.AA ULK 3-177 26 5.4e-43 149.16 In-house 96-324 (324) Show / Hide 
Range on Protein: 3-177
Range on HMM: 96-324/324
Sequence Identity: 26% (60 aa)

MEYCPN-DLFNLLK---------GNTNVTEDQMLRYMHDILIAIKACHDRNIAHNDIKPSNFLLDKY------------GRIKMCDFGLSRMYDE-----
||||.  ||....|          . . .|.. . ....|. . |. |..|| | ||||.| |. .             |..| .|||.... |.     
MEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQ

-HCMSSC----YRGTMLFMAPELFK----KSPYNPLKADIWSIGITFFYIATRSFPFFAADKQVYI----KSLNSG------IYPQFIVQN---------
  |.. .    ..|| |.|||....    . ||.  |.||||.|. |... . . |||.  .. ..    | .| |      |. | |  .         
QMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKIS

PQLRVLIQSCLQVNPEARPTIDELLQMPYF
|... ||. .||.... | ...|....| |
PECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 96280.m00182.AA ULK 3-177 26 1.6e-42 146.26 In-house 99-329 (329) Show / Hide 
Range on Protein: 3-177
Range on HMM: 99-329/329
Sequence Identity: 26% (61 aa)

MEYCPN-DLFNLLK----------GNTNVTEDQMLRYMHDILIAIKACHDRNIAHNDIKPSNFLLDKY------------GRIKMCDFGLSRMYDEH---
||||.  ||....|           . . .|.. . ....|| . |. |..|| | ||||.| |...             |..| .|||.... |.    
MEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNME

---CMSSC----YRGTMLFMAPELFK----KSPYNPLKADIWSIGITFFYIATRSFPFFA-ADKQV---YIKSLNSG------IYPQFIVQN--------
    |.      ..|| |.|||....    . ||.  |.||||.|. |... .   ||.| . .|.   ..| .| .      |  | .  .        
QQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQI

-PQLRVLIQSCLQVNPEARPTIDELLQMPYF
 |... ||. .||.... | ...||...| |
SPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 96280.m00182.AA Ciliate-E2 1-177 23 1.3e-41 140.63 In-house 111-365 (365) Show / Hide 
Range on Protein: 1-177
Range on HMM: 111-365/365
Sequence Identity: 23% (62 aa)

MLMEYCPN-DLFNLLK------------GNTNVTEDQMLRYMHDIL---------------IAIKACHDRN-IAHNDIKPSNFLLDKYGRIKMCDFGLSR
. ||||   ||| ..|            .  . || .....|  ||                |.. .| .| | | ||||.| |.     || .|||||.
LVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSK

MYDE------HCMSSCY---------------------------RGTMLFMAPELFKKSPY--------NPLKADIWSIGITFFYIATRSFPFFAADKQV
 ||.      | .. |.                            ||  .|||| ... .|           |.||||.|.....  .  .||    .| 
KYDDDNQNRTH-KQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF---QQQI

YIKSLNSGIYP-------------QFIVQNPQLRVLIQS----CLQVNPEARPT-IDELLQMPYF
  . ..   .               .    ..   ||.     .||..|| |.| ....|. |.|
KQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 96280.m00182.AA Ciliate-E2-Unclassified 3-177 23 2.6e-39 133.99 In-house 100-352 (352) Show / Hide 
Range on Protein: 3-177
Range on HMM: 100-352/352
Sequence Identity: 23% (60 aa)

MEYC------------------PNDLFNLLKGNTNVTEDQML-----RYMHDILIAIKACHDRN-IAHNDIKPSNFLLDKYG---RIKMCDFGLSRMYDE
||||                   ||||. .| .  .|| |..     .|.  || ... .|  | | | ||||.| |.|. |   .|| .|||.|. |..
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

----------------HCMSSCYRGTMLFM----APELFKKSPYNP---LKADIWSIGITFFYIATRSFPFFAADKQV----------------YIKSLN
                ..|..   ||  .|    |||....  |.     |.|||| |. .... .  .||.. ..                  ...  .
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

SGIYPQF---------IVQNPQ---LRVLIQSCLQVNPEARPTIDELLQMPYF
 ... ..         .... .   .. |.|..|..||. |.|....|. |.|
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 96280.m00182.AA MARK 32-177 39 2.8e-37 119.51 In-house 113-262 (262) Show / Hide 
Range on Protein: 32-177
Range on HMM: 113-262/262
Sequence Identity: 39% (60 aa)

ILIAIKACHDRNIAHNDIKPSNFLLDKYG--RIKMCDFGLSRMYDEHCMSSCYRGTMLFMAPELFKKSPYNPLKADIWSIGITFFYIATRSFPFF-AA--
|. |.. ||..||.| |||| | |.|. |   || .|||.|.   . .. .   ||  .||||.|.| ||.  |.|||| |.  ... . .|||  .   
IVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQD

DKQVYIKSLNSGIY-PQFIVQNPQLRVLIQSCLQVNPEARPTIDELLQMPYF
.|. | | |.     | .    ...| |||. |.|||| ||||.|... | .
YKELYKKILRGKYDIPCH--VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 96280.m00182.AA CAMKK-Unclassified 21-177 24 7.1e-32 100.89 In-house 176-392 (392) Show / Hide 
Range on Protein: 21-177
Range on HMM: 176-392/392
Sequence Identity: 24% (53 aa)

TEDQMLRYMHDILIAIKACHDRN---------------------IAHNDIKPSNFLLDKYGR-----IKMCDFGLSRMYDEHCMS--SCYRGTMLFMAPE
.|.. ..|. ... ... .|..|                     | | |||| | |.|. ..     .| .|||.| .   .  .  .   ||  |||||
HEQYLKKYFRQCCKGLQYMHNFNQACSYIIIYINEFDKIDHFQDIIHRDIKPQNILIDHEDNDKGEHFKIADFGISVIMEHEQQKKLKNNAGTYCFMAPE

LFKKS--PYNPLK-------------------------ADIWSIGITFFYIATRSFPFFAADKQVYIK-SLNSGI--YP-QFIVQN-PQLRVLIQSCLQV
.. |.   |...                          ||||| |.||..... | ||.. . |.  .  .  ..   | |..  . ...  |||...  
FWSKENFKYDYNDYSFLPGTFNPLRKTYRIERICFYKKADIWSLGVTFYCMVYHSLPFWHKNLQELFHQMICQKEINFPPQYHPHCSHEFKDLIQKMCDK

NPEARPTIDELLQMPYF
||. | ||| .|  |.|
NPKKRITIDQMLVHPWF
Kinase 96280.m00182.AA CMGC 1-124 21 4.8e-25 78.45 In-house 132-343 (513) Show / Hide 
Range on Protein: 1-124
Range on HMM: 132-343/513
Sequence Identity: 21% (45 aa)

MLMEYCPNDLFNLLKGNT---------NVTEDQ------------MLRYM------HDILIAIK--ACHDRN--IAHNDIKPSNFLLD------------
. .||...||....| |          . .| .               .|      . || ..|   || ..  | | |.||.| |..            
LVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWK

--------KYGRIKMCDFGLSRMYDEH----------------------CMSSCYRGTMLFMAPELFKKSPYNP---------LKADIWSIGITFFYIAT
        | ||.| |||||.| |..|                       . . |  |.   |||.   ...            . |.||.|  |. . |
SEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYT

R-------SFPFF
.         |.|
GYQSLIFRGKPLF
Kinase 96280.m00182.AA S_TKc 2-177 24 8.5e-23 82.98 SMART 1-231 (231) Show / Hide 
Range on Protein: 2-177
Range on HMM: 1-231/231
Sequence Identity: 24% (63 aa)

L----------------------------------------------------------------MEYCPN---DLFNLLKGNTN------VTEDQMLRY
                                                                 ||||..   ||| ..| .         .| .  .|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFY

MHDILIAIKACHDRNIAHNDIKPSNFLLDKYGRIKMCDFGLSRMYDEHCMSSCYRGTMLFMAPELFKKSPYNPLKADIWSIGITFFYIATRSFPFFAADK
|. |. |.. ||...| | |.||.| |||.  .|| |||||.| .      . . ||  .||||..   .|.. |.|.||.|....  ...  ||   . 
MYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QM

QVYIKSLNSGIYPQFIVQNPQLRVLIQSCLQVNPEARPTIDELLQ-------MPYF
|. .| .            |... .|. |||..|| |||. |.||       .|.|
QMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 96280.m00182.AA NEK 3-110 32 3.3e-22 75.31 In-house 85-211 (286) Show / Hide 
Range on Protein: 3-110
Range on HMM: 85-211/286
Sequence Identity: 32% (42 aa)

MEYCP--NDLFNL---LKGNT----NVTEDQMLRYMHDILIAIKACHDR-----NIAHNDIKPSNFLLDKYGR----IKMCDFGLSRMYDEH--CMSSCY
||||    ||...   .| ..    .  |.| ....  ...|.| .|||     .| | ||||.|  |.| ..    .|. |||.|.. .    . .. .
MEYCEGGGDLYQKIKSIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQ

RGTMLFMAPELFKKSPYNPLKADIWSIG
 ||  .|.||...  |||  |.||||.|
VGTPYYMSPEVCQNKPYNN-KSDIWSLG
Kinase 96280.m00182.AA NEK 148-177 40 1.3e-10 34.03 In-house 257-286 (286) Show / Hide 
Range on Protein: 148-177
Range on HMM: 257-286/286
Sequence Identity: 40% (12 aa)

PQLRVLIQSCLQVNPEARPTIDELLQMPYF
..|. ||...||..|| ||.....|.||. 
QDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase 96280.m00182.AA CMGC 142-177 36 2.4e-09 25.88 In-house 478-513 (513) Show / Hide 
Range on Protein: 142-177
Range on HMM: 478-513/513
Sequence Identity: 36% (13 aa)

QFIVQNPQLRVLIQSCLQVNPEARPTIDELLQMPYF
.   ..||.. |.. .|| .|. |.|... ||.|||
KRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase 96280.m00182.AA TyrKc 1-175 17 4e-06 -123.63 SMART 1-280 (280) Show / Hide 
Range on Protein: 1-175
Range on HMM: 1-280/280
Sequence Identity: 17% (48 aa)

M---------------------------------------------L------------------------------MEYCPN-DLFNLLKGNTN-VTED
                                              |                              |||.|. || . |. . . .. .
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

QMLRYMHDILIAIKACHDRNIAHNDIKPSNFLLDKYGRIKMCDFGLSRMYDEH----CMSSCYR-----GTM--L---FMAPELFKKSPYNPLKADIWSI
..| ....|       |..|. | |.   | |... ...| .||||||  ...      .. ||     |.   |    |||| .... ... | |.|| 
DLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT-KSDVWSF

GITFFYIATRSFPFF-------AADKQVYIKSLNSGIYPQFIV--------QNPQLRVLIQSCLQVNPEARPTIDELLQMP
|.. . | |.  .           ...|. .  . .  ||             . .  ....| . .|| |||  |. .  
GVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF