86244.m00029

Species: T.vaginalis
Alias: TvagK0916, 86244.m00029
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CRK7-like

Sequence

Name Sequence Type Origin Length Description Download
86244.m00029.AA Protein None 328 None Fasta, JSON
86244.m00029.kin_dom Protein Kinase Domain None 276 None Fasta, JSON

Protein domain

Protein domains of 86244.m00029.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 86244.m00029.AA CMGC 2-276 21 4.7e-83 272.63 In-house 17-513 (513) Show / Hide
Range on Protein: 2-276
Range on HMM: 17-513/513
Sequence Identity: 21% (106 aa)

KAIDPTNG--------------EVVAIKKVR-IFNQNQAL--------PQAFYRETSNLQTLK-----------------HPNIINLREIFRSNS--GEE
|..|  ..              |.|||||..  |...||.        |.  .|| . |. |.                 |.||..|..||...   |.|
KCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNIVKLYDIFYHKNSDGNE

P-------------YMVFDYCEFDLDGLIHSRNT-----KGLPL-------------QTVKCYF------KQILNAVK--ACHDLN--IVHRDLKPANIF
.             |.||.|.. || ..|.. ..     ...||             ...|...      .|||...|   ||  .  |.||||||.|| 
YEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENIL

ITRDNVV--------------------KLGDFGLSRDLTKG---------------------NSQRTLGVVTPGYRAPEIILGNTQYD---------YSS
|. .. .                    |..||||.| . .                      | . |  |||  ||||||.|| ..|.         .. 
INHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPI

DIWSLGAILFEMLTG--------IPLFRPLTS---------SDISQLAAIVFVLGKPN---------------ENDFANNSC------------------
|.||.| |..||.||         ||| . ..         |.| ||. |. |||.|.               |... | ..                  
DMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKLPWYNKFPKKWNWQTMTN

----SNINLLNMVRDSDRSLEGILSECLVG-----------------------------------ESAEAIPLILGMLKYNPSQRITVDEALCSQFL
    .  | ... ..  .     ...   .                                   .. .|| |. .||.|.|..|||...||   ..
HWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF

S_TKc 86244.m00029.AA S_TKc 1-276 27 2.1e-80 274.31 SMART 16-231 (231) Show / Hide
Range on Protein: 1-276
Range on HMM: 16-231/231
Sequence Identity: 27% (81 aa)

MKAIDPTNGEVVAIKKVRIFNQNQALPQAFYRETSNLQTLKHPNIINLREIFRSNSGEEPYMVFDYCEF---DLDGLIHSRNTKG----LPLQTVKCYFK
.|...   |..||||...         . ..|| . |.  .||||..| ..|..   .. |||..||.    ||  .|..|...|    .|  ....|..
YKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMY

QILNAVKACHDLNIVHRDLKPANIFITRDNVVKLGDFGLSRDLTKGNSQRTLGVVTPGYRAPEIILGNTQYDY-SSDIWSLGAILFEMLTGIPLFRPLTS
||..|.. ||...|.||||||.||....  ..|..||||.| |       |  ..|| |.|||..    .|.. ..|.||.| ||.|||.| |.|.    
QICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCGYPPFP----

SDISQLAAIVFVLGKPNENDFANNSCSNINLLNMVRDSDRSLEGILSECLVGESAEAIPLILGMLKYNPSQRITVDEALC-------SQFL
    |....  ..|                                       | ||. .| ..|...|..|.|. |||         ...
----QMQMMFKKIG---------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 86244.m00029.AA Pkinase 2-276 28 1.6e-77 268.68 Pfam 17-293 (293) Show / Hide
Range on Protein: 2-276
Range on HMM: 17-293/293
Sequence Identity: 28% (84 aa)

KAIDPTNGEVVAIKKVRIFNQNQALPQAFYR--ETSNLQTLKHPNIINLREIFRSNSGEEPYMVFDYCEF-----DLDGLIHSRNTKGL--PLQTVKCYF
|...  .|..||.|...  ...   .|.  |  | . .. |.||||. |...|..  . ..|||..|||      ||  .|. .. ...  . ...|.|.
KCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYM

KQILNAVKACHDLNIVHRDLKPANIFITRDNVV----KLGDFGLSRDL-TKGNSQRTLGVVTPGYRAPEIILGNTQYDYSSDIWSLGAILFEMLTGIPLF
.||| ... ||. .|.||||||.||.| .....    |..||||.. . .  ||  |  ..||.|.|||.|.|.. |....|.||.| ||.|||.| |.|
YQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPF

RPL--TSSDISQLAAIVFVLGKPNENDFANNSC-SNINLLNMVRDSDRSLEGILSECLVGESAEAIPLILGMLKYNPSQRITVDEALCSQFL
.    . . ..|.. |. ..|.|.. |. . .. |. . ..  . .      ....  .  | |.. .| ..|...|..|.| ...|.. ..
PGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H------FHWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 86244.m00029.AA CDK 2-212 33 1.7e-69 221.49 In-house 17-248 (284) Show / Hide
Range on Protein: 2-212
Range on HMM: 17-248/284
Sequence Identity: 33% (83 aa)

KAIDPTNG-----EVVAIKKVRIFNQ-----NQALPQAFYRETSNLQTLKHPNIINLREIFRSNSGE---------EPYMVFDYCEFDLDGLIHSRNTKG
||.|  .|     ..||.||.|. |.        .|.   || | |. | ||||..|.... ... .           ||||.|.. || ....      
KARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEYMDHDLKKYMD------

LPLQTVKCYFKQILNAVKACHDLNIVHRDLKPANIFITRDNV-----VKLGDFGLSRDLTK------GNSQRTLGVVTPGYRAPEIILGNTQYD--YSSD
     .|||..|.|...  ||. .|.||||||.|| |... .     .|..||||.|           |   |  |||  |||||. || ..|.   . |
-----IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPELLLGSKHYSGGTPID

IWSLGAILFEMLT---GIPLFRPLTSSDISQLAAIVFVLGKPNEND
.||.| |. ||.|   . |||    .|.| ||  |  ..| |.|..
MWSVGCIFAEMFTDVTRKPLFP--GDSEIDQLFKIFRICGTPTEDN

Kinase 86244.m00029.AA CDC2 2-213 40 1.9e-66 203.02 In-house 17-233 (301) Show / Hide
Range on Protein: 2-213
Range on HMM: 17-233/301
Sequence Identity: 40% (89 aa)

KAIDPTNGEVVAIKKVRIFNQNQA--LPQAFYRETSNLQTLK-HPNIINLREIFRSNSGEEPYMVFDYCEFDLDGLIH-SRNT-KGLPLQTVKCYFKQIL
|..|   ...||.||.|. ...     |.   || | |. || ||||. |.... .      ||||.|...||  .   |  . | .|.|.|| |..|||
KCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYLDMDLKKYMDMSIPKNKHMPPQLVKSYMYQIL

NAVKACHDLNIVHRDLKPANIFITRDNVVKLGDFGLSRDLTKGNSQRTLG--VVTPGYRAPEIILGNTQYDYSSDIWSLGAILFEM---LTGIPLFRPLT
..|  ||   |.|||||| ||.| .. ..|..||||.|. .    . | .  |||  |||||| ||  .|. . |.||.| |. ||    |  |||    
QGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEMFMDVTKKPLFH--G

SSDISQLAAIVFVLGKPNENDF
 | | ||  |  .|| |||...
DSEIDQLFKIFRILGTPNEQTW

Kinase 86244.m00029.AA MAPK 2-276 31 1.7e-57 197.35 In-house 17-328 (328) Show / Hide
Range on Protein: 2-276
Range on HMM: 17-328/328
Sequence Identity: 31% (98 aa)

KAIDPT------NGEVVAIKKVRIFNQNQALPQAFYRETSNLQTL-KHPNIINLREIFRS------NSG---EEPYMVFDYCEFDLDGLIHSRNTKGLPL
.|||        .|. |||||.    ||. . .  |||   |. . .|.|||.|..||.       ||    .. |.|....| ||  .|.|..   |  
SAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMETDLHQIIKSQQ--PLSD

QTVKCYFKQILNA--VKACHDLNIVHRDLKPANIFITRDNVVKLGDFGLSRDLTKGNSQR--------------TLGVVTPGYRAPEIILG--NTQYDYS
. ..  . |||..  .|  |  |..||||||.|| .. .  .|..||||.| .    ...              |  |.|  ||||||.|.   . |. .
DHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAPEIMLNWIWMHYTKA

SDIWSLGAILFEMLT-GIPLFRPLTSSDISQLAAIVFVLGKPNENDFANNS-CSNI-NLLNMV----RDSDRSLEGILSECLVGESAEAIPLILGMLKYN
 |.||.| |. |||| . |||.   .. | |.  |. |||.| | .  . . ...  |..       .   ...| ...  . . . .|| |.  ||  .
VDMWSVGCIFAEMLTDRKPLFP--GKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQAIDLLEKMLVFD

PSQRITVDEALCSQFL
|..||||.|||   ..
PDKRITVEEALQHPYF

Kinase 86244.m00029.AA Ciliate-E2 33-276 26 1.2e-55 189.44 In-house 82-365 (365) Show / Hide
Range on Protein: 33-276
Range on HMM: 82-365/365
Sequence Identity: 26% (85 aa)

ETSNLQTLKHPNIINLREIFRSNSGEEPYMVFDYCEF-DLDGLIHSRNTKG---------LPLQTVKCYFKQILN---------------AVKACHDLN-
| ..|..|.|||||.. | | ... .  |.|..||.  ||  .| ....|          . .. .| ..||||.               |.. .|  | 
EKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN

IVHRDLKPANIFITRDNVVKLGDFGLSRDLTKGNS-----------------QRTLG--------------VVTPGYRAPEIILG--------NTQYDYS
|.|||.|| ||..     .|. |||||..... |                   || |              . |||| ||||. |         ..|||.
IIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYK

SDIWSLGAILFEMLTGIPLFRPLTSSDISQLAAIVFVLGKPNENDFANNSCSNINLLNMVRDSDRSLEGILSECLV----GESAEAIPLILG----MLKY
.|||||| ||.|||.| | |                         . ..   .|.. .   ..| ..  |   | .      | |.. ||      ||..
CDIWSLGVILYEMLFGKPPF-------------------------QQQIKQCKIDFPCPEWQKD-TQ-CI-Q-CKWKSWKKWSQECKDLIKKFGKRMLQK

NPSQRIT-VDEALCSQFL
.|..|||  ...|  ...
DPEKRITGWEQILNHPWF

Kinase 86244.m00029.AA ERK7 2-276 34 1.6e-54 184.73 In-house 17-292 (292) Show / Hide
Range on Protein: 2-276
Range on HMM: 17-292/292
Sequence Identity: 34% (97 aa)

KAIDPTNGEVVAIKKVRIFNQNQALPQAFYRETSNLQTLK-HPNIINLREIFRSNSGEEPYMVFDYCEFDLDGLIHSRNTKGLPLQTV--KCYFKQILNA
||.|   ..|||.||.    .||   |  .||   || .. ||||| | ...| .     |.||.. | ||   |     ||  |. .  .. . |.|.|
KAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIRADNDRDIYLVFEFMETDLHAVIR----KGNILKDIHKQYIMYQLLRA

VKACHDLNIVHRDLKPANIFITRDNVVKLGDFGLSRDLTKGN------SQRTLGVVTPGYRAPEIILGNTQYDYSSDIWSLGAILFEMLTGIPLFRPLTS
.|  |  |..||||||.|| .  . .||. |||| | ... .        .|  | |  |||||| || ..|    | ||.| || |||.| |.|    .
IKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCILGEMLRGKPMFP--GT

SDISQLAAIVFVLGKPNENDFAN-NSCSNINLLNMVRDSDRSLEGILSECLVGESAEAIPLILGMLKYNPSQRITVDEALCSQFL
| . |.  |. ...|| . | .  .|   .|.|. .    .. .  |.. . . . .|| |.  .| .|| .|.|...||   . 
STMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMN---QQKRKTLDQMMPQCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV

Kinase 86244.m00029.AA ULK 7-185 30 3.4e-49 169.74 In-house 24-250 (324) Show / Hide
Range on Protein: 7-185
Range on HMM: 24-250/324
Sequence Identity: 30% (69 aa)

TN--GEVVAIKKVRIFNQNQALPQ--------AFYRETSNLQTLK---HPN--IINLREIFRSNSGEEPYMVFDYCEF-DLDGLIHSRNT-------KGL
||  ...||.|.. ....|.   .         . .| .....||   |||  |. | ..|..      |....||.  ||. .|. ...       | |
TNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPETEEKKRL

PLQTVKCYFKQILNAVKACHDLNIVHRDLKPANIFITRDN------------VVKLGDFGLSRDLTKGNSQRTLG---V------VTPGYRAPEIILGN-
. | .. .||||.|. |. |. ||.|||.||.|| |. ..            |.|..|||... . ..| . ..    |       || | ||.|. |. 
SEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQG

---TQYDYSSDIWSLGAILFEMLTGIP
    .||| .|||||| |..|||.| .
EQKPYYDYKCDIWSLGCIFYEMLYGKY

Kinase 86244.m00029.AA CAMK 2-185 21 5.1e-49 155.67 In-house 12-332 (425) Show / Hide
Range on Protein: 2-185
Range on HMM: 12-332/425
Sequence Identity: 21% (70 aa)

KAIDP-TNG-----------EVVAIKKVR-----------------IFNQ---------NQALPQAFYRETSNLQT-------LKHPNIINLREIFRS--
..|.  |.|           . |||| .                  |...         ..   . ..|| . ...       |.|||||.| |.. .  
LCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKLYEVYEDPH

---------NSGE-------EPYMVF---DYC---EF--DLDGLIHSRNT-------------KGLPLQTVKCYFKQILNAVKACHDLNIVHRDLKPANI
         .          . |||.   .||   |   ||   | ..               . .. . .. ||.||. ||. ||..||||||||| ||
YFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENI

FITRD-----------------NVVKLGDFGLSRDLTKGNSQRTL-----------------------GVVTPGYRA-PEIILG-------------NTQ
 .. .                 | .|. |||... ...|......                        . ||.| | ||...|             .. 
LLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPY

YDYSSDIWSLGAILFEMLTGIP
|....|.||.| ||. ||.| |
YGPKCDMWSCGVILYIMLCGYP

Kinase 86244.m00029.AA ULK 2-185 30 4.7e-48 165.83 In-house 17-254 (329) Show / Hide
Range on Protein: 2-185
Range on HMM: 17-254/329
Sequence Identity: 30% (74 aa)

KAI-DPTN---GEVVAIKKVR-----IFNQN---QALPQAFYRETSNLQTLK--------HPNIINLREIFRSN-SGEEPYMVFDYCEF-DLDGLIHSRN
|..   |.   .|.||.|..      ..|..   | . | . .|  ....||        ||||. | ..|..  .    |....||.  ||. .|. ..
KGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNH-NNIYIIMEYCNGGDLEQYIKKNK

T--------KGLPLQTVKCYFKQILNAVKACHDLNIVHRDLKPANIFITRDN------------VVKLGDFGLSRDLTKG--NSQRTLGVV-------TP
.        | |. | .. .||||||. |. |. ||.|||.||.|| |. ..            |.|..|||... ....  . | ..  |       ||
KLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTP

GYRAPEIILGN----TQYDYSSDIWSLGAILFEMLTGIP
 | ||.|. |.     .||| .|||||| |..|||.| |
LYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKP

Kinase 86244.m00029.AA CDKL 8-207 41 3.9e-45 152.27 In-house 23-218 (286) Show / Hide
Range on Protein: 8-207
Range on HMM: 23-218/286
Sequence Identity: 41% (83 aa)

NGEVVAIKKVRIFNQNQALPQAFYRETSNLQTLKHPNIINLREIFRSNSGEEPYMVFDYCEFD-LDGLIHSRNTKGLPLQTVKCYFKQILNAVKACHDLN
.|..|||||      ...      ||   | .|||.|| ||.|.|| .   . ..|| ||.   |. | .  . .|.. . |. |  |||.|.. ||  |
TGQIVAIKKFKESEDDPMVKKIAMREIKMLKQLKHENIVNLIEVFRRK--RKLHLVFEYCDHTVLHELEE--YPNGVDEHVVRKYMWQILKAINFCHKHN

IVHRDLKPANIFIT-RDNVVKLGDFGLSRDLTKGNSQRTLGVVTPGYRAPEIILGNTQYDYSSDIWSLGAILFEMLTGIPLFRPLTSSDISQLAAIVFVL
..||| || ||.|| .. .|||.|||. | |.| .   |  | |  |||||  .| |||  . |||..| .. ||..| ||. |  .||| ||  |. .|
CIHRDIKPENILITPKNGQVKLCDFGFARMLAKPGEIYTDYVATRWYRAPELLVGDTQYGKPVDIWAIGCVMAEMIDGQPLW-P-GQSDIDQLYHIQKCL

GK
|.
GP

Kinase 86244.m00029.AA Pkinase_Tyr 12-182 27 9.8e-16 53.92 Pfam 31-209 (270) Show / Hide
Range on Protein: 12-182
Range on HMM: 31-209/270
Sequence Identity: 27% (50 aa)

VAIKKVRIFNQNQA-LPQAFYRETSNLQTL-KHPNIINLREIFRSNSGE-EPYMVFDYCEF-DLDGLIHSR--NTKGLPLQTVKCYFKQILNAVKACHDL
||.|...     .. . ..| || . . .| .||||..|  .  . ..  ..|.|. |..  ||.   ...  . . |....  ..  || ..    .. 
VAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESK

NIVHRDLKPANIFITRDNVVKLGDFGLSRDL-TKGNS--QRTLGVVTPGYRAPEIILGNTQYDYSSDIWSLGAILFEMLT
|..||||   |. .|..|||| .||||.||.  ...   .|. | .     ||| |  .  .   ||.|| |  ..|..|
NCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTKSDVWSFGVLMWEIFT

Kinase 86244.m00029.AA TyrKc 2-275 19 1.6e-13 -4.04 SMART 19-280 (280) Show / Hide
Range on Protein: 2-275
Range on HMM: 19-280/280
Sequence Identity: 19% (59 aa)

KAIDPTNGEVVAIKKVRIFNQNQALPQAFYRETSNLQTL--KHPNIINLREIFRSNSG-----EEPYMVFDYCEF-DLDGLIHSRNTKGLPLQTVKCYFK
...     . ||.|...         ..|.|| . .  |  .||||..|  . .. ..     | ...|. |..  ||.  ....  | |....   .  
TWK-----IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK-LCMKDLLSFCW

QILNAVKACHDLNIVHRDLKPANIFITRDNVVKLGDFGLSRDLTKG-------NSQRT----LGV--VTPGYRAPEIILGNTQYDYSSDIWSLGAILFEM
|| .     |. |..||||   |. ......|| .|||||||.. .          |.     |   .     ||| |     .   ||.|| |  ..|.
QIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFTTKSDVWSFGVCMWEI

LTGIPLFRP------LTSSDISQLAAIVFVLGKPNE----NDFANNSCSNINLLNMVRDSDRSLEGILSECLVGESAEAIPLILGMLKYNPSQRITVDEA
.|      |      .. ... ..    . . .| .                                .   |. ..|   ...   ...|..| |  | 
FTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS---------------------------F---VCCPDEMYQIMKQCWHEDPEDRPTFSEI

LCSQF
 ...|
-HECF

Kinase 86244.m00029.AA CDK 252-276 36 2.5e-08 22.6 In-house 260-284 (284) Show / Hide
Range on Protein: 252-276
Range on HMM: 260-284/284
Sequence Identity: 36% (9 aa)

LILGMLKYNPSQRITVDEALCSQFL
|. .|| |.|..||. ..|| ....
LLNKMLCYDPKKRISAEQALQHPYF

Kinase 86244.m00029.AA CAMK 246-276 32 4e-08 21.53 In-house 395-425 (425) Show / Hide
Range on Protein: 246-276
Range on HMM: 395-425/425
Sequence Identity: 32% (10 aa)

SAEAIPLILGMLKYNPSQRITVDEALCSQFL
|.|.. || .||...|..|.|....|  ...
SQECKDLIRKMLQVDPEKRMTIEQCLNHPWM

Kinase 86244.m00029.AA CDC2 248-276 41 1.1e-07 19.11 In-house 273-301 (301) Show / Hide
Range on Protein: 248-276
Range on HMM: 273-301/301
Sequence Identity: 41% (12 aa)

EAIPLILGMLKYNPSQRITVDEALCSQFL
|.| |.  || |.|..||...|||   ..
EGIDLLMQMLQYDPQKRISAKEALQHPYF

Kinase 86244.m00029.AA ULK 252-276 32 6e-05 13.31 In-house 305-329 (329) Show / Hide
Range on Protein: 252-276
Range on HMM: 305-329/329
Sequence Identity: 32% (8 aa)

LILGMLKYNPSQRITVDEALCSQFL
|| .||.|....||. .| .   ..
LIRRMLQYDEKDRISWEELFNHPWF

Kinase 86244.m00029.AA CDKL 246-276 16 0.000394 10.02 In-house 256-286 (286) Show / Hide
Range on Protein: 246-276
Range on HMM: 256-286/286
Sequence Identity: 16% (5 aa)

SAEAIPLILGMLKYNPSQRITVDEALCSQFL
...|. .. ..|. .|..|.|..... . . 
NKKALDFMKKCLHMDPDERMTCEQLMHHPYF

Kinase 86244.m00029.AA ULK 252-276 32 0.001123 8.99 In-house 300-324 (324) Show / Hide
Range on Protein: 252-276
Range on HMM: 300-324/324
Sequence Identity: 32% (8 aa)

LILGMLKYNPSQRITVDEALCSQFL
|| .||.|....||. .| .   ..
LIRRMLQYDEKDRISWEEIFNHPWF