Gene 87835.m00290 (T.vaginalis)

87835.m00290

Species: T.vaginalis
Alias: 87835.m00290, TvagK0918
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CRK7-like

Sequence

Name Sequence Type Origin Length Description Download
87835.m00290.AA Protein None 326 None Fasta, JSON
87835.m00290.kin_dom Protein Kinase Domain None 276 None Fasta, JSON

Protein domain

Protein domains of 87835.m00290.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 87835.m00290.AA CMGC 2-276 20 1.8e-87 287.36 In-house 17-513 (513) Show / Hide 
Range on Protein: 2-276
Range on HMM: 17-513/513
Sequence Identity: 20% (103 aa)

KAIDPKNG--------------DIVAIKRVK-VFNSSQS---------LPQSFYRETSNLQHLK-----------------HENIINLREVFRPSNSNVP
|..| ...               |||||..| .|              .|.. .|| . |.||.                 |.||..|...|...||. .
KCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNIVKLYDIFYHKNSDGN

---------------YMVFDYCEFDLDGLIHNR---YSN----GLDNKT------------VKSYF------KQILTAVK--FCHDNN--IIHRDLKPSN
               |.||.|.. || ..|.|    | .    .|.               .|...      .|||...|  .|| ..  ||||||||.|
EYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPEN

IFVTRDNVV--------------------KLGDFGLSRDLSKG---------------------SPRMTLNVVTPGYRAPELILGNSEYD---------T
| .. .. .                    |..||||.| ...                      .  .| .|||  |||||..|| ..|.         |
ILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTT

SSDIWSLGTILFEMITG--------VPLFKPLTS---------SDISQLASIVFVMGKPN---------------PDEISPKCANSNI------------
. |.||.| |..||.||         |||.. ..         |.| ||. |. |.|.|.               ..|.  .  . .             
PIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKLPWYNKFPKKWNWQTM

-----------LNM---VSRTSGVPFEDFLRENLQ-------------------------------GEAAAAIPLIFSMLRYNPEERISIEEALCSSFF
           ...     .  . |....   .                                  .   || |.  ||.|.|..||..|.||   .|
TNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase 87835.m00290.AA Pkinase 2-276 28 2.3e-79 274.76 Pfam 17-293 (293) Show / Hide 
Range on Protein: 2-276
Range on HMM: 17-293/293
Sequence Identity: 28% (84 aa)

KAIDPKNGDIVAIKRVKVFNSSQSLPQSFYR--ETSNLQHLKHENIINLREVFRPSNSNVPYMVFDYCEF-----DLDGLIHNRYSNGL--DNKTVKSYF
|... ..|.|||.|..|. . . . .|.  |  | . ...|.|.||. |...|.   .. .|||..|||      ||  .|. ......  . ...|.|.
KCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYM

KQILTAVKFCHDNNIIHRDLKPSNIFVTRDNVV----KLGDFGLSRDL-SKGSPRMTLNVVTPGYRAPELILGNSEYDTSSDIWSLGTILFEMITGVPLF
.||| ....||...||||||||.||.. .....    |..||||.. .    .. ||  ..||.|.|||.|.|...|....|.||.| ||.||..| |.|
YQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPF

KPL--TSSDISQLASIVFVMGKPNPDEISPKCANSNILNMVSRTSGVPFEDFLRENLQGEAAAAIPLIFSMLRYNPEERISIEEALCSSFF
.    . . ..|.. |. .||.|.. ... .| .|.   .  |.   .  . ....      ... .| ..|...|..|...|..|.. .|
PGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYF--F-FRH-W-H--F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
S_TKc 87835.m00290.AA S_TKc 1-276 28 2.9e-76 260.6 SMART 16-231 (231) Show / Hide 
Range on Protein: 1-276
Range on HMM: 16-231/231
Sequence Identity: 28% (82 aa)

MKAIDPKNGDIVAIKRVKVFNSSQSLPQSFYRETSNLQHLKHENIINLREVFRPSNSNVPYMVFDYCEF---DLDGLIHNRYSNG----LDNKTVKSYFK
.|... | | |||||..|         ....|| . |.. .|.||..| .||.    .  |||..||.    ||  .|..| ..|    ..  ....|..
YKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMY

QILTAVKFCHDNNIIHRDLKPSNIFVTRDNVVKLGDFGLSRDLSKGSPRMTLNVVTPGYRAPELILGNSEYDT-SSDIWSLGTILFEMITGVPLFKPLTS
||. |...||...||||||||.||....  ..|..||||.| |       |  ..|| |.|||..     |.. ..|.||.| ||.||..| |.|     
QICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCGYPPFP----

SDISQLASIVFVMGKPNPDEISPKCANSNILNMVSRTSGVPFEDFLRENLQGEAAAAIPLIFSMLRYNPEERISIEEALC-------SSFF
    |.. .  ..|                                          |. .|  .|...||.|... |||          .|
----QMQMMFKKIG---------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 87835.m00290.AA CDK 2-211 34 2.9e-75 240.21 In-house 17-247 (284) Show / Hide 
Range on Protein: 2-211
Range on HMM: 17-247/284
Sequence Identity: 34% (84 aa)

KAIDPKNG-----DIVAIKRVKVFN-----SSQSLPQSFYRETSNLQHLKHENIINLREVFRPSNS---------NVPYMVFDYCEFDLDGLIHNRYSNG
||.| ..|     .|||.|.... |         .|..  || | |..| |.||..|..|.  .|.         |  ||||.|.. || ....      
KARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEYMDHDLKKYMD------

LDNKTVKSYFKQILTAVKFCHDNNIIHRDLKPSNIFVTRDNV-----VKLGDFGLSRDLSK------GSPRMTLNVVTPGYRAPELILGNSEYD--TSSD
     .|.|..|.| .. .||.|.|.||||||.|| .... .     .|..||||.|  .        .  .| .|||  |||||| || ..|.  |. |
-----IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPELLLGSKHYSGGTPID

IWSLGTILFEMIT---GVPLFKPLTSSDISQLASIVFVMGKPNPD
.||.| |. ||.|   . |||    .|.| ||  |  ..| |..|
MWSVGCIFAEMFTDVTRKPLFP--GDSEIDQLFKIFRICGTPTED
Kinase 87835.m00290.AA CDC2 2-187 38 6.3e-68 207.67 In-house 17-209 (301) Show / Hide 
Range on Protein: 2-187
Range on HMM: 17-209/301
Sequence Identity: 38% (76 aa)

KAIDPKNGDIVAIKRVKVFNSSQS--LPQSFYRETSNLQHLK-HENIINLREVFRPSNSNVPYMVFDYCEFDLDGLIHNRYS--NGLDNKTVKSYFKQIL
|..| . ..|||.|.... . .     |..  || | |. || |.||. |..|.     |  ||||.|...||  .  .  .    ..  .||||..|||
KCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYLDMDLKKYMDMSIPKNKHMPPQLVKSYMYQIL

TAVKFCHDNNIIHRDLKPSNIFVTRDNVVKLGDFGLSRDLSKGSPRMT--LNVVTPGYRAPELILGNSEYDTSSDIWSLGTILFEM---ITGVPLF
 .| ||| . |.||||||.||.. .. ..|..||||.|. .  .   |   .|||  |||||. || . |.|. |.||.| |. ||   .|  |||
QGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEMFMDVTKKPLF
Kinase 87835.m00290.AA MAPK 2-276 31 6.8e-66 225.23 In-house 17-328 (328) Show / Hide 
Range on Protein: 2-276
Range on HMM: 17-328/328
Sequence Identity: 31% (100 aa)

KAIDPK------NGDIVAIKRVK-VFNSSQSLPQSFYRETSNLQHL-KHENIINLREVFRPS-----NS----NVPYMVFDYCEFDLDGLIH-NRYSNGL
.||| .      .|..||||..  .|.. ..     |||   |.|. .|||||.|...|.|.     ||    |  |.|....| ||  .|. ..    |
SAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCK-RTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMETDLHQIIKSQQ---PL

DNKTVKSYFKQILTA--VKFCHDNNIIHRDLKPSNIFVTRDNVVKLGDFGLSRDLSKGSP--------------RMTLNVVTPGYRAPELILG--NSEYD
... ... . ||| .  .|. |  |.|||||||||| |. .  .|..||||.| .   .                || .|.|  |||||..|.    .|.
SDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAPEIMLNWIWMHYT

TSSDIWSLGTILFEMIT-GVPLFKPLTSSDISQLASIVFVMGKPNPDEISPKCA-NSNILNMVSR------TSGVPFEDFLRENLQGEAAAAIPLIFSML
.. |.||.| |. ||.| . |||.   .. | |.  |. |.|.| ..|   .   ...  |....      . ..|.|. .  .. .    || |.. ||
KAVDMWSVGCIFAEMLTDRKPLFP--GKDYIDQWNLIMEVLGTP-SEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQAIDLLEKML

RYNPEERISIEEALCSSFF
  .|..||..||||   .|
VFDPDKRITVEEALQHPYF
Kinase 87835.m00290.AA ERK7 2-276 33 4.7e-52 176.2 In-house 17-292 (292) Show / Hide 
Range on Protein: 2-276
Range on HMM: 17-292/292
Sequence Identity: 33% (95 aa)

KAIDPKNGDIVAIKRVKVFNSSQSLPQSFYRETSNLQHLK-HENIINLREVFRPSNSNVPYMVFDYCEFDLDGLIHNRYSNGLDNKTVKSYFKQILTAVK
||.| . ...||.|..      |   |  .||   || .. |.||| | .|.| .|    |.||.. | ||   |  |  | | .  ... . |.| |.|
KAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIRADNDRDIYLVFEFMETDLHAVI--RKGNILKDIHKQYIMYQLLRAIK

FCHDNNIIHRDLKPSNIFVTRDNVVKLGDFGLSRDLSKGS------PRMTLNVVTPGYRAPELILGNSEYDTSSDIWSLGTILFEMITGVPLFKPLTSSD
. |  |.|||||||||| .  . .||. |||| | ...        | .|  | |  |||||  ||  .|    | ||.| || ||..| |.|    .| 
YMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCILGEMLRGKPMFP--GTST

ISQLASIVFVMGKPNPDEIS---PKCANSNILNMVSRTSGVPFEDFLRENLQGEAAAAIPLIFSMLRYNPEERISIEEALCSSFF
. |.  |. ...||   .|    ...| .|.|. . ..   .......    .   .|| |.  .| .||..|...|.||   . 
MNQIEKILETIPKPTQEDIEAIGSHYA-WNMLEQMNQQKRKTLDQMMP----QCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV
Kinase 87835.m00290.AA Ciliate-E2 33-276 22 8.5e-52 176.07 In-house 82-365 (365) Show / Hide 
Range on Protein: 33-276
Range on HMM: 82-365/365
Sequence Identity: 22% (78 aa)

ETSNLQHLKHENIINLREVFRPSNSNVPYMVFDYCEF-DLDGLIHNR----------YSNGLDNKTVKSYFKQILT---------------AVKFCHDNN
| ..|..|.| |||.. |.|   . |  |.|..||.  ||  .| |.          . . .. | .| ..||||                |....| .|
EKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKN

-IIHRDLKPSNIFVTRDNVVKLGDFGLSRDLSKG----------SPRMTLN----------------------VVTPGYRAPELILGNSE--------YD
 |||||.||.||..     .|. |||||.....              |  .                      . |||| ||| . | ..        ||
NIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYD

TSSDIWSLGTILFEMITGVPLFKPLTSSDISQLASIVFVMGKPNPDEISPKCANSNILNMVSRTSGVPFEDFLRENLQGEAA------------------
...|||||| ||.||..| | |                                                  .....|..                    
YKCDIWSLGVILYEMLFGKPPF--------------------------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWK

-------AAIPLIFS----MLRYNPEERIS-IEEALCSSFF
        .. ||      || ..||.||. .|..|   .|
SWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 87835.m00290.AA CDKL 8-207 44 6.3e-49 165.41 In-house 23-218 (286) Show / Hide 
Range on Protein: 8-207
Range on HMM: 23-218/286
Sequence Identity: 44% (89 aa)

NGDIVAIKRVKVFNSSQSLPQSFYRETSNLQHLKHENIINLREVFRPSNSNVPYMVFDYCEFD-LDGLIHNRYSNGLDNKTVKSYFKQILTAVKFCHDNN
.| |||||. |     ..      ||   |  |||||| ||.||||    .  ..|| ||.   |. | .  | ||.| . |..|  ||| |..||| .|
TGQIVAIKKFKESEDDPMVKKIAMREIKMLKQLKHENIVNLIEVFR--RKRKLHLVFEYCDHTVLHELEE--YPNGVDEHVVRKYMWQILKAINFCHKHN

IIHRDLKPSNIFVT-RDNVVKLGDFGLSRDLSKGSPRMTLNVVTPGYRAPELILGNSEYDTSSDIWSLGTILFEMITGVPLFKPLTSSDISQLASIVFVM
.|||| || ||..| .. .|||.|||. | |.| .   |  | |  |||||| .|  .| .. |||..| .. |||.| ||. |  .||| ||  |. ..
CIHRDIKPENILITPKNGQVKLCDFGFARMLAKPGEIYTDYVATRWYRAPELLVGDTQYGKPVDIWAIGCVMAEMIDGQPLW-P-GQSDIDQLYHIQKCL

GK
|.
GP
Kinase 87835.m00290.AA CDK10 2-276 33 2e-48 166.45 In-house 17-285 (285) Show / Hide 
Range on Protein: 2-276
Range on HMM: 17-285/285
Sequence Identity: 33% (93 aa)

KAIDPKNGDIVAIKRVKVFNSSQSLPQSFYRETSNLQHLKHENIINLREVFRPSNSNVPYMVFDYCEFDLDGLIHNRYSNGLDNKTVKSYFKQILTAVKF
.| | .  .|||.|.|..      || |  ||   | ...||||..|.||      .  ..| .||| ||  |. |  ..      ||    |.| ..|.
RARDMRSDEIVALKKVRMDKEKDGLPISGLREIMLLIQCRHENIVELHEVVVGQHLDSIFLVMQYCEQDLASLLDN-MPQPFTETQVKCIMLQMLRGLKY

CHDNNIIHRDLKPSNIFVTRDNVVKLGDFGLSRDLSKGSPRMTLNVVTPGYRAPELILGNSEYDTSSDIWSLGTILFEMITGVPLFKPLTSSDISQLASI
 ||| .|||||| ||. .| .  .|. |||| |  .     ||  .||  ||||||.||  .  |. |.| .| || |.. . ||.    .|.| |.  |
LHDNFMIHRDLKVSNLLMTDKGCIKVADFGLARMYGVPVKPMTPKMVTLWYRAPELLLGCRTQTTAIDMWAVGCILGELLVHKPLMP--GNSEIHQIDMI

VFVMGKPNPDEISPKCANSNILNMVSRTSGVPFEDFLRENLQGEAAAAIPLIFSMLRYNPEERISIEEALCSSFF
. ..| |. ..| |  ..  . .  .  .  |.   |..  .  . .   |.  .. ||| .|   ||.| ||.|
IDLLGTPS-ENIWPGFSDLPMVQNFT-LKKQPYNN-LKHKFHWLSQSGRRLLNFLFMYNPKKRATAEECLESSYF
Kinase 87835.m00290.AA CDK4 2-208 39 7.5e-47 158.68 In-house 17-228 (290) Show / Hide 
Range on Protein: 2-208
Range on HMM: 17-228/290
Sequence Identity: 39% (86 aa)

KAIDPKNGDIVAIKRVKVFNSSQ--SLPQSFYRETSNLQHLK---HENIINLREVFRPSNSNV----PYMVFDYCEFDLDGLIHNRYSNGLDNKTVKSYF
.| |...| .|| |.|.. ..     .|.|  || | . ||.   | ||. | .|.  .          |||  |. ||  .. .    |.  .|.|   
RARDLHTGHFVALKQVRIPIGEEGGGMPMSTIREISVMRHLCQFEHPNIVKLMDVCHVMDTDRAEMKITMVFEHCDWDLHTYLDKCPPPGMPPCTIKHMM

KQILTAVKFCHDNNIIHRDLKPSNIFVTRDNVVKLGDFGLSRDLSKGSPRMTLNVVTPGYRAPELILGNSEYDTSSDIWSLGTILFEMITGVPLFKPLTS
.|.|..| | | . |||||||| || ||.|  ||| ||||.|  |     .|  |||  |||||  |  | | |  |.||.| | .||    |||    .
HQLLRGVDFLHSHRIIHRDLKPQNILVTSDGHVKLADFGLARIYSFQM-ALTPVVVTLWYRAPEVLL-QSYYNTPVDMWSVGCIFAEMYCRRPLF--CGQ

SDISQLASIVFVMGKP
|.  ||  |  ||| |
SEKDQLHKIFDVMGLP
Kinase 87835.m00290.AA ULK 2-185 27 3.8e-43 148.47 In-house 17-254 (329) Show / Hide 
Range on Protein: 2-185
Range on HMM: 17-254/329
Sequence Identity: 27% (65 aa)

KAIDPKN----GDIVAIKRVK--VFNSSQSLPQ------SFYRETSNLQHLK--------HENIINLREVFRPSNSNVPYMVFDYCEF-DLDGLIHNR--
|... |.    . .||.| .    .| .. . .      .. .|  ... ||        |.||. | ..|. ||.|  |....||.  ||. .|...  
KGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKK

------YSNGLDNKTVKSYFKQILTAVKFCHDNNIIHRDLKPSNIFVTRDN------------VVKLGDFGLSRDLSKG--SPRMTLNVV-------TPG
      . . |  . ....||||| . |. |..||||||.||.|| .. ..            |.|..|||... ....  . .|..  |       || 
LPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPL

YRAPELIL---GNSEYDTS-SDIWSLGTILFEMITGVP
| ||...    .. .|... .||||||.|..||..| |
YMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKP
Kinase 87835.m00290.AA Pkinase_Tyr 12-182 30 7.2e-17 57.76 Pfam 31-209 (270) Show / Hide 
Range on Protein: 12-182
Range on HMM: 31-209/270
Sequence Identity: 30% (56 aa)

VAIKRVKVFNSSQS-LPQSFYRETSNLQHL-KHENIINLREVFR-PSNSNVPYMVFDYCEF-DLDGLIHNR--YSNGLDNKTVKSYFKQILTAVKFCHDN
||.| .|   ...  . ..| || . . .| .|.||..|  |    . .| .|.|. |..  ||.   ...    . |. |.  ..  ||  .  . ...
VAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESK

NIIHRDLKPSNIFVTRDNVVKLGDFGLSRDL-------SKGSPRMTLNVVTPGYRAPELILGNSEYDTSSDIWSLGTILFEMIT
|.|||||   |. ||..|||| .||||.||.        |..  . | .      ||| |  .  . | ||.|| |  ..|..|
NCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIK---WMAPECINYGK-FTTKSDVWSFGVLMWEIFT
Kinase 87835.m00290.AA TyrKc 2-275 21 2.4e-13 -6.86 SMART 19-280 (280) Show / Hide 
Range on Protein: 2-275
Range on HMM: 19-280/280
Sequence Identity: 21% (64 aa)

KAIDPKNGDIVAIKRVKVFNSSQSLPQSFYRETSNLQHL--KHENIINLREVFRPS-----NSNVPYMVFDYCEF-DLDGLIHNRYSNGLDNKTVKSYFK
...       ||.| .|         . |.|| . . .|  .|.||..|  | . .      .  ...|. |..  ||.  ....  . | .|.  |.  
TWK-----IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK-LCMKDLLSFCW

QILTAVKFCHDNNIIHRDLKPSNIFVTRDNVVKLGDFGLSRDLSKG-----SPRMTLNVVTPGYR--------APELILGNSEYDTSSDIWSLGTILFEM
||     . |..|.|||||   |. |.....|| .|||||||.  .     |  .     . | .        ||| |   ... | ||.|| |  ..|.
QIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFTTKSDVWSFGVCMWEI

IT-GVPLFKP-----LTSSDISQLASIVFVMGKPNP--DEISPKCANSNILNMVSRTSGVPFEDFLRENLQGEAAAAIPLIFSMLRYNPEERISIEEALC
 | | .         .. ... ..    . | .|      .|                      |        ..    .. .  ...||.| . .|  .
FTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYP-MS----------------------F----VCCPDEMYQ-IMKQCWHEDPEDRPTFSEI-H

SSF
. |
ECF
Kinase 87835.m00290.AA CDC2 249-276 46 9.6e-09 22.45 In-house 274-301 (301) Show / Hide 
Range on Protein: 249-276
Range on HMM: 274-301/301
Sequence Identity: 46% (13 aa)

AIPLIFSMLRYNPEERISIEEALCSSFF
.| |. .||.|.|. |||..|||   .|
GIDLLMQMLQYDPQKRISAKEALQHPYF
Kinase 87835.m00290.AA CDK 252-276 48 1.3e-07 20.25 In-house 260-284 (284) Show / Hide 
Range on Protein: 252-276
Range on HMM: 260-284/284
Sequence Identity: 48% (12 aa)

LIFSMLRYNPEERISIEEALCSSFF
|. .|| |.|. ||| |.|| . .|
LLNKMLCYDPKKRISAEQALQHPYF
Kinase 87835.m00290.AA ULK 252-276 44 3e-06 17.97 In-house 305-329 (329) Show / Hide 
Range on Protein: 252-276
Range on HMM: 305-329/329
Sequence Identity: 44% (11 aa)

LIFSMLRYNPEERISIEEALCSSFF
||  || |....|||.|| .   .|
LIRRMLQYDEKDRISWEELFNHPWF
Kinase 87835.m00290.AA CDK4 249-276 32 1.7e-05 14.62 In-house 263-290 (290) Show / Hide 
Range on Protein: 249-276
Range on HMM: 263-290/290
Sequence Identity: 32% (9 aa)

AIPLIFSMLRYNPEERISIEEALCSSFF
.. |.  ||.||.. |.| ...|  ..|
GDDLLQKMLCYNHHKRMSAYQCLQHPYF
Kinase 87835.m00290.AA CDKL 238-276 20 6.7e-05 12.69 In-house 247-286 (286) Show / Hide 
Range on Protein: 238-276
Range on HMM: 247-286/286
Sequence Identity: 20% (8 aa)

LRENLQGEA-AAAIPLIFSMLRYNPEERISIEEALCSSFF
|.. ...   ..|. .. ..|  .| ||.. |... ...|
LEKRYPNKSNKKALDFMKKCLHMDPDERMTCEQLMHHPYF