Gene 82414.m00147 (T.vaginalis)
82414.m00147
Species: T.vaginalis
Alias: 82414.m00147, TvagK0854
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
---|---|---|---|---|---|
82414.m00147.AA | Protein | None | 183 | None | Fasta, JSON |
82414.m00147.kin_dom | Protein Kinase Domain | None | 133 | None | Fasta, JSON |
Protein domains of 82414.m00147.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 82414.m00147.AA | MARK | 1-132 | 35 | 5.3e-43 | 138.51 | In-house | 123-258 (262) | Show / Hide |
Range on Protein: 1-132 Range on HMM: 123-258/262 Sequence Identity: 35% (48 aa) MGIAHRDLKPSNLLIDQYN--RIKIADFGLAVSAEKNQKITRFGGSLTFSSPEIIKGLKHDPFKADIWALGITFYCLVFGKIPYTATT--EDELKQQISD ..|.|||.|| |.|||. . |||.|||... . .|| ..| |.. . .|||... . | .|.|||.||. | .| |. |. ..| . ||...| KNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILR AKITIPATCDKRISIILDMILKPDPDERPTAAGVLQ | .|| | . .. .|...|.||||. ... GKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMK |
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Kinase | 82414.m00147.AA | CAMKL | 1-127 | 29 | 3.5e-40 | 125.83 | In-house | 146-288 (297) | Show / Hide |
Range on Protein: 1-127 Range on HMM: 146-288/297 Sequence Identity: 29% (43 aa) MGIAHRDLKPSNLLIDQYN--RIKIADFGLAVSAEK-----NQKITRFGGSLTFSSPEIIKG--LKHDPFKADIWALGITFYCLVFGKIPYTATT----- .||.|||.|| |.|.|. . |||.|||.. .. .|| . | ||. . .|||..| ..| .|.|||..|.. | .|.|. | . | HGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQG ----EDELKQQISDAKITIPATCDKRISIILDMILKPDPDERPTA . ..|. . ...|. . . .. .|...|..|||. KDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTI |
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Kinase | 82414.m00147.AA | CAMK | 1-132 | 19 | 5.8e-37 | 116.13 | In-house | 198-421 (425) | Show / Hide |
Range on Protein: 1-132 Range on HMM: 198-421/425 Sequence Identity: 19% (43 aa) MGIAHRDLKPSNLLIDQY-----------------NRIKIADFGLAVSAEK------------------------NQKITRFGGSLTFSS-PEIIKG--- ..|.|||||| |.|.|. | |||.|||.| .. .|| . | |.. . . ||...| HNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGH ----------LKHDPFKADIWALGITFYCLVFGKIPYTAT-------------TEDELKQQISDAKIT-IPAT-----------------------CDKR . ...|.|.|..|. | .. |. |. . .. ||...| .| . .| ... CNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQE ISIILDMILKPDPDERPTAAGVLQ . .|..||..|.|.. .|. CKDLIRKMLQVDPEKRMTIEQCLN |
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Kinase | 82414.m00147.AA | Ciliate-E2-Unclassified | 2-132 | 24 | 1.6e-32 | 110.17 | In-house | 164-348 (352) | Show / Hide |
Range on Protein: 2-132 Range on HMM: 164-348/352 Sequence Identity: 24% (46 aa) GIAHRDLKPSNLLIDQYN---RIKIADFGLAVSAEKN----------------QKITRFGGSLTFS----SPEIIKGLKHDP---FKADIWALGITFYCL .| |||.||.|.|.|. . .|||.|||.. ..| |... | |.. . .||...| ..| .|.|||.||. .|.. NIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEM VFGKIPYTATTEDE----------------LKQQISDAKITIPATCD----KRIS---IILDM-----ILKPDPDERPTAAGVLQ .||. |. ...... |.|.| . .| .| |..| . . .|| .|..|.|. .|. LFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILN |
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Kinase | 82414.m00147.AA | CAMKK | 5-94 | 30 | 1.6e-32 | 100.17 | In-house | 219-341 (396) | Show / Hide |
Range on Protein: 5-94 Range on HMM: 219-341/396 Sequence Identity: 30% (38 aa) HRDLKPSNLLIDQYN---RIKIADFGLAVSAE-KNQKITR-----------FGGSLTFSSPEIIKGLKHDP---------------FKADIWALGITFYC |||.||.|.|||. . ..|||||| ... | .|.. . | .| || . . . ..|||||||.|.|| HRDIKPQNILIDEEGCGEHVKIADFGVSHIFEGQDQTLSNCESCFQRELNKTAGTPAFMAPELCSKENQKENYNGYKYRFRFIYCGKAADIWALGVTLYC LVFGKIPYTATTEDELKQ---QI .||||.|. .... .|. .| FVFGKCPFWHNNLMQLHHNYMKI |
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Kinase | 82414.m00147.AA | Pkinase | 1-134 | 28 | 9.8e-31 | 109.75 | Pfam | 127-293 (293) | Show / Hide |
Range on Protein: 1-134 Range on HMM: 127-293/293 Sequence Identity: 28% (49 aa) MGIAHRDLKPSNLLIDQYNRI----KIADFGLAVS--AEKNQKITRFGGSLTFSSPEIIKGLKHDPFKADIWALGITFYCLVFGKIPYTAT------TED ||| ||||||.|.|||. . | ||.||||| .|. | | |.. . .||.|.| .... |.|.|..|...|....|. |. ... MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQM ELKQQISD--AKITIPATCD-------------------KRISIILDMILKPDPDERPTAAGVLQI--F .. ..| . . .| .|. . ... .|..|| .||||. .|| | QMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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Kinase | 82414.m00147.AA | Ciliate-E2 | 2-132 | 24 | 3.9e-29 | 97.14 | In-house | 180-361 (365) | Show / Hide |
Range on Protein: 2-132 Range on HMM: 180-361/365 Sequence Identity: 24% (48 aa) G-IAHRDLKPSNLLIDQYNRIKIADFGLAVSAEKN----------QKITRFG-----------------------GSLTFSSPEIIKGLK--------HD . | |||.||.|.|. |||.||||. . .. .... . |.. . .|||..| | . NNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGY PFKADIWALGITFYCLVFGKIPYTATTEDELKQQISDAKITIPATC--------------DKRISII-LDMILK-------PDPDERPT-AAGVLQ .|.|||.||...|...||| |. ||| . || .| . | .| |.| | ||..|.| . .|. DYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN |
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Kinase | 82414.m00147.AA | CAMKK-Unclassified | 3-131 | 29 | 1.2e-28 | 90.23 | In-house | 220-387 (392) | Show / Hide |
Range on Protein: 3-131 Range on HMM: 220-387/392 Sequence Identity: 29% (50 aa) IAHRDLKPSNLLIDQYNR-----IKIADFGLAVSAE-KNQK-ITRFGGSLTFSSPEIIKGL--KHDPFK-------------------------ADIWAL | |||.|| |.|||. . .||||||..|. | .|| . | ..| .|| . | |. ||||.| IIHRDIKPQNILIDHEDNDKGEHFKIADFGISVIMEHEQQKKLKNNAGTYCFMAPEFWSKENFKYDYNDYSFLPGTFNPLRKTYRIERICFYKKADIWSL GITFYCLVFGKIPYTATTEDELKQ-QISDAKITIPA-----TCDKRISIILDMILKPDPDERPTAAGVL |.||||.|....|. ... ||. .| ..| | . .. | |. | .|..| |. ..| GVTFYCMVYHSLPFWHKNLQELFHQMICQKEINFPPQYHPHCSHEFKDLIQKMCDK-NPKKRITIDQML |
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Kinase | 82414.m00147.AA | ULK | 1-124 | 23 | 1.4e-26 | 91.32 | In-house | 145-312 (324) | Show / Hide |
Range on Protein: 1-124 Range on HMM: 145-312/324 Sequence Identity: 23% (39 aa) MGIAHRDLKPSNLLIDQYN------------RIKIADFGLAVSAEKNQKITRFG----------GSLTFSSPEIIKGL----KHDPFKADIWALGITFYC ..| |||.||.|.|| . ..||||||.| . ..|.. |. . .|.|..|. ... .|.||| ||. || HNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYE LVFGKIP---YTATTED----ELKQQ-------ISDAKITIP-----ATCDKRISIILDMILKPDPDER ...|| | . ..... .|... | . .| .| . . . .. |. |...| MLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDR |
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Kinase | 82414.m00147.AA | ULK | 1-124 | 22 | 1.6e-25 | 86.07 | In-house | 149-317 (329) | Show / Hide |
Range on Protein: 1-124 Range on HMM: 149-317/329 Sequence Identity: 22% (38 aa) MGIAHRDLKPSNLLIDQYN------------RIKIADFGLAVSAEKN----QKITRFG------GSLTFSSPEIIKGL----KHDPFKADIWALGITFYC ..| |||.||.| ||. . ..||||||.| . ... | .. . |. . .|.|..|. ... .|.||| ||. || HNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYE LVFGKIP---YTATTED-----ELKQQ-------ISDAKITIP-----ATCDKRISIILDMILKPDPDER ...|| | . ..... .|... | . .. .| .. . . .. |. |...| MLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDR |
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Kinase | 82414.m00147.AA | TKL | 1-134 | 17 | 4.6e-25 | 87.21 | In-house | 159-364 (364) | Show / Hide |
Range on Protein: 1-134 Range on HMM: 159-364/364 Sequence Identity: 17% (36 aa) MGIAHRDLKPSNLLIDQYNR--------------IKIADFGLA--VSAEKNQKITR------------------FGGSLTFSSPEIIKGLKHDP------ ..|.|||||..|.|.|. .. .||.||||. .| ..|.. | .|.. . .||...| .. PPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGID ---------FKADIWALGITFYCLVFGKIPYT-ATTEDEL------KQQISDA----KITIP------------ATCDKRISIILDMILKPDPDERPTAA |.|... || .. .. ...|| .... .. .. . .|| .|..... .. . ..||..||.. EFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQ GVLQIF .|... EILKRL |
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Kinase | 82414.m00147.AA | S_TKc | 1-137 | 16 | 3.3e-09 | -41.9 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 1-137 Range on HMM: 1-231/231 Sequence Identity: 16% (41 aa) M---------------------------------------------------------------------G----------------------------- | YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPEHARFYM --------------IAHRDLKPSNLLIDQYNRIKIADFGLAVSAEKNQKITRFGGSLTFSSPEIIKGLKHDPFKADIWALGITFYCLVFGKIPYTATTED | ||||||.|.|.|. .|||.||||| | | |.. . .||.. .....|.|.|..|...| .. |. |. ... YQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQ ELKQQISDAKITIPATCDKRISIILDMILKPDPDERPTAAGVLQ------IFNYI .. ..| .. ... .|. ||..|||| .|| . .. MMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |