Gene 91566.m00136 (T.vaginalis)

91566.m00136

Species: T.vaginalis
Alias: 91566.m00136, TvagK0705
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
91566.m00136.AA Protein None 236 None Fasta, JSON
91566.m00136.kin_dom Protein Kinase Domain None 176 None Fasta, JSON

Protein domain

Protein domains of 91566.m00136.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 91566.m00136.AA CAMK 1-111 20 1.5e-34 108.23 In-house 132-321 (425) Show / Hide 
Range on Protein: 1-111
Range on HMM: 132-321/425
Sequence Identity: 20% (39 aa)

MFVIL---EYCSNG----SVLDLLLKQNQ---------------LSGRKILTIVSQLAAAIEVCHSNSVAHHDIKPNNILIDEY----------------
|. ..   ||||.|     ..| . .. .               .. |   ... |.. |.. |||. ..| |.|| |||.|.                 
MYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWN

-NQVKLADFGMSTHLEG--------------------------ISTKFMGSINLLA-PEVINK-------------SPYDPFSADIWSFG
 |..|..|||.......                            . | |.    | |||.|.              ||.....|.|| |
NNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCG
Kinase 91566.m00136.AA CAMKL 1-111 32 2.2e-33 103.77 In-house 96-223 (297) Show / Hide 
Range on Protein: 1-111
Range on HMM: 96-223/297
Sequence Identity: 32% (41 aa)

MFVILEYCSNGS--VLDLLLKQNQ----LSGRKILTIVSQLAAAIEVCHSNSVAHHDIKPNNILIDEYN--QVKLADFGMSTH---L----EGISTKFMG
.. ..||||.|.   .| . |.      .. .    .  |. .|.. |||. ..| |||| |||.|| .  ..|..|||.|..        .   . | |
IYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCG

SINLLAPEVINK--SPYDPFSADIWSFG
| .  |||....   ||| . .|||| |
SPPYMAPEIFQGNNKPYDGPKVDIWSCG
Kinase 91566.m00136.AA Pkinase 1-176 21 7.1e-30 106.72 Pfam 75-293 (293) Show / Hide 
Range on Protein: 1-176
Range on HMM: 75-293/293
Sequence Identity: 21% (47 aa)

MFVILEYCSNG----SVLDLLL--KQNQL--SGRKILTIVSQLAAAIEVCHSNSVAHHDIKPNNILIDEYNQV----KLADFGMS----THLEGISTKFM
. ...||| .|    .  |..   ... .  | . .  .. |.. ..| |||... | |.|| |||||. ...    |..||| .    .   .  | | 
IYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFC

GSINLLAPEVINKSPYDPFSADIWSFGATILALIVSDWFLKGI------PSHKAQLMVQSGEIQIPEETP---------------------HELIEIIKH
|... .|||||....|.. ..|.||.| ..  ..      .|          .   .. ....  .....                      |....|| 
GTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKW

SMIRDPEKRWNITQITNY--L
   .||.||....|| .   .
CLCKDPKKRPTAEQILQHPWF
Kinase 91566.m00136.AA Ciliate-E2 4-174 19 1.3e-29 98.76 In-house 112-361 (365) Show / Hide 
Range on Protein: 4-174
Range on HMM: 112-361/365
Sequence Identity: 19% (52 aa)

ILEYCSNGSVLDLLLKQNQLSG-----------RKILTIVSQLAA---------------AIEVCHSNS-VAHHDIKPNNILIDEYNQVKLADFGMSTHL
..|||. |. .|.. .... ..           ..|..|  |..                |.| .||.  . | ||||.|||.     .|..|||.|. .
VMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKY

E------------GISTKFM-----------------------GSINLLAPEVINKSPYDP--------FSADIWSFGATILALIVSDW-FLKGIPSHKA
             .. .                          |. . .|||..|. .||         ...||||.| ..  ..   . |         
DDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF---------

QLMVQSGEIQIP------------------EETPHELIEIIKH----SMIRDPEKRWN-ITQITN
|   . ..|..|                  .. . | . .||      . .||||| . . || |
QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN
Kinase 91566.m00136.AA MARK 2-111 37 3.8e-28 89.25 In-house 78-193 (262) Show / Hide 
Range on Protein: 2-111
Range on HMM: 78-193/262
Sequence Identity: 37% (43 aa)

FVILEYCSNGSVLDLLLKQ--NQLSGRKILTIVSQLAAAIEVCHSNSVAHHDIKPNNILIDEYN--QVKLADFGMSTHL--EGISTKFMGSINLLAPEVI
..|.||.|.|...| . ..    |. .   .| .|.  |.. |||....| |||| |||||| .  ..|..|||.|..   .   . | |.    |||..
YLIMEYASGGELYDYIKAHPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIF

NKSPYDPFSADIWSFG
.| ||| . .|||| |
LKKPYDGPKVDIWSLG
Kinase 91566.m00136.AA Ciliate-E2-Unclassified 4-111 22 6.7e-27 90.35 In-house 99-257 (352) Show / Hide 
Range on Protein: 4-111
Range on HMM: 99-257/352
Sequence Identity: 22% (36 aa)

ILEYCSNGSVLDLLLKQNQ-----------------LSGRKIL-----TIVSQLAAAIEVCHSNS-VAHHDIKPNNILIDEYN---QVKLADFGMSTHLE
..||| .|. .. . |...                 .. ....     ..  |.  ..| .|..  . | ||||.|||.|. .   ..|..||| | ...
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

------------------GISTKFMGSINLL----APEVINKSPYDP---FSADIWSFG
                   ... |.|..| .    ||||. .  ||    ...||||.|
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLG
Kinase 91566.m00136.AA STE 2-171 21 2.9e-26 89.81 In-house 113-350 (359) Show / Hide 
Range on Protein: 2-171
Range on HMM: 113-350/359
Sequence Identity: 21% (52 aa)

FVILEYCSNGSVLDLLL----KQNQLS----------GRKILTIVSQLAAA-IEVCHSNSVAHHDIKPNNILIDEYNQVKLADFGMSTHLEG--------
....||...||. |..     ....|.             | .|. |.  .  .  ||. . | |||| |||.     |||.||| .. |.         
WICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSN

-----------ISTKFMGSINLLAPEVINK------SPYDPFSADIWSFGATILALIVSDWFLKGIPSHKAQLMVQ----------------SGEIQIPE
            .. | |.    |||||..      ..|| ...||||.| ||. ..     .   . ..| .| .                 .  ..|.
NIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYD-TKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPD

ETP-------------------HELIEIIKHSMIRDPEKRWNITQ
..                     |... |..  ..||.||.. .|
HLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ
Kinase 91566.m00136.AA GIN4 1-172 29 4.3e-26 79.99 In-house 109-287 (293) Show / Hide 
Range on Protein: 1-172
Range on HMM: 109-287/293
Sequence Identity: 29% (54 aa)

MFVILEYCSNGSVLDLLLKQNQLSGRKILTIVSQLAAAIEVCHSNSVAHHDIKPNNILIDEYNQ-VKLADFGMSTHLEGISTKFM----GSINLLAPEVI
....|||   | . ..| .. .|  |  . .  |.   .  ||.  . | |.|| |.|.|. .. .|.|||||   || .  | .    ||    |||..
LYLVLEYAEKGELFNYLVDHGPLPEREAIHYFRQIIIGVSYCHAFNICHRDLKPENLLLDHKYNRIKIADFGMAA-LE-TDNKLLETSCGSPHYAAPEIV

NKSPYDPFSADIWSFGATILALIVSDWFLKGI--PSHKAQLMVQSGEIQIPEE--TPHELIEIIKHSMIRDPEKRWNITQI
   ||. |..|.|| |  . ||.             .|  | ||.|. ..|..     |  ..|.  .. |||||  . .|
MGIPYHGFASDVWSCGVILFALLTGHLPFDEEDGNIRKLLLKVQKGKYEMPSDDEISREAQDLIRKILVVDPEKRIKTRDI
Kinase 91566.m00136.AA TKL 1-176 17 7.5e-26 90.06 In-house 113-364 (364) Show / Hide 
Range on Protein: 1-176
Range on HMM: 113-364/364
Sequence Identity: 17% (45 aa)

MFVILEYCSNGSVLDLLLKQNQLSGRKILTIVSQLAAAIEVCHSNS--------VAHHDIKPNNILIDEYNQ--------------VKLADFGMSTHLEG
.. . |||..|| |..|.        ... .. . | ...  ||.         ..| |.|..|||.|| ..              .|..||| |. ...
LCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQ

I----------------------STKFMGSINLLAPEVINKSPYDP---------------FSADIWSFGATILALIVSDWFLKGIPSHKAQ--------
                       . .  |... .||||........                ..|..|||  .  ..   .  ...|.   .        
SGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEM

-LMVQ--SGEIQIP------------EETPHELIEIIKHSMIRDPEKRWNITQITNYL
  ||   .    ||            . .|......... .  ||||| . ..|. .|
FMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 91566.m00136.AA STE11 3-115 29 2.5e-25 88.7 In-house 90-229 (303) Show / Hide 
Range on Protein: 3-115
Range on HMM: 90-229/303
Sequence Identity: 29% (42 aa)

VILEYCSNGSVLDLLL-KQNQ--LSGRKILTIVSQLAAAIEVCHSNSVAHHDIKPNNILIDEYNQ-VKLADFGMSTHLEGISTK-------------FMG
...|||..||. ..|  |.    ..   |   . |.  ..   ||. . | |||. |||.| ... .|||||| .. |..| |.             . |
IFMEYCPGGSLSSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTG

SIN--------LLAPEVINKSP---YDPFSADIWSFGATIL
...          |||||....   |.  .|||||.|.|..
TPYNSMMGTPMWMAPEVIKQEGRDGYGR-KADIWSLGCTVI
Kinase 91566.m00136.AA QIK 1-174 28 1.1e-22 81.7 In-house 73-268 (272) Show / Hide 
Range on Protein: 1-174
Range on HMM: 73-268/272
Sequence Identity: 28% (55 aa)

MFVILEYCSNGSVLDLLLKQNQ--------------------LSGRKILTIVSQLAAAIEVCHSNSVAHHDIKPNNILIDEYNQVKLADFGMSTHLEGIS
|... ||||||   | | |. .                    .. ..   . .|...|.. ||.  ..| |.|  |||.|.   .|.||||.| . ..  
MYIVTEYCSNGEMFDYLCKHGRKGVKMVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQ

--TKFMGSINLLAPEVINKSPYDPFSADIWSFGATILALIVSDWFLKGIPSHKAQLMVQSGEIQIPEETPHELIEIIKHSMIRDPEKRWNITQITN
    . ||    |||.     ||   .|||| |    .|.       |   .. .  | ||  .||   . .. ..|.| .. |||.| .| || .
LLMTWCGSPPYAAPEMFEGKEYDGPKVDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQ
Kinase 91566.m00136.AA S_TKc 2-176 18 1.5e-14 36.27 SMART 1-231 (231) Show / Hide 
Range on Protein: 2-176
Range on HMM: 1-231/231
Sequence Identity: 18% (48 aa)

FVIL--------------------------------------------------------------EYCSN--GSVLDLLLKQNQ------LSGRKILTI
. ||                                                              |||..  |...|.. |..       ..   .  .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFY

VSQLAAAIEVCHSNSVAHHDIKPNNILIDEYNQVKLADFGMSTHLEGISTKFMGSINLLAPEVINKSPYDPFSADIWSFGATILALIVSDWFLKGIPSHK
. |.. |.| |||. . | |.|| |||.||  ..|..|||....|    | | |. . .||||.   .|.....|.||.| ..  ...          . 
MYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP----QM

AQLMVQSGEIQIPEETPHELIEIIKHSMIRDPEKRWNITQITN---------YL
.... . |        ..|....|.. . .|||||. . .. .         ..
QMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 91566.m00136.AA TyrKc 1-176 18 1.2e-07 -99.24 SMART 1-280 (280) Show / Hide 
Range on Protein: 1-176
Range on HMM: 1-280/280
Sequence Identity: 18% (52 aa)

M---------------------------------------------F----------------------------VILEYCSNGSVLDLLLKQNQ-LSGR
                                              .                            ...||...|. .| | |    |. .
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

KILTIVSQLAAAIEVCHSNSVAHHDIKPNNILIDEYNQVKLADFGMSTHLEGI----------------STKFMGSINLLAPEVINKSPYDPFSADIWSF
. | .  | |.  |  ||. . | |.   |.|..| ..|| .|||.|  ..                  ..|.|  |  .|||.||.. . . | |.|||
DLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS-DVWSF

GAT---ILALIVSDWFLKG-----IPSHKAQLMVQSG-EIQIPEE--------TPHELIEIIKHSMIRDPEKRWNITQITNYL
| .   |. .  . .   |     ..   .   |..|    .|..         | |. .|.|    .|||.| . ..|  ..
GVCMWEIFTYGQQPYP--GMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 91566.m00136.AA CAMK 135-172 17 0.006608 4.4 In-house 358-419 (425) Show / Hide 
Range on Protein: 135-172
Range on HMM: 358-419/425
Sequence Identity: 17% (11 aa)

MVQSGEIQ-IPEETPH-----------------------ELIEIIKHSMIRDPEKRWNITQI
....|. . .|.. ..                       | .  |.. . .|||||..|.|.
KIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQC
Kinase 91566.m00136.AA Pkinase_Tyr 56-73 50 0.006821 10.42 Pfam 141-158 (270) Show / Hide 
Range on Protein: 56-73
Range on HMM: 141-158/270
Sequence Identity: 50% (9 aa)

NILIDEYNQVKLADFGMS
|.|..| |.|| .|||..
NCLVTENNVVKICDFGLA
Kinase 91566.m00136.AA CAMKL 135-172 26 0.021508 3.28 In-house 256-291 (297) Show / Hide 
Range on Protein: 135-172
Range on HMM: 256-291/297
Sequence Identity: 26% (10 aa)

MVQSGEIQIPEETPHELIEIIKHSMIRDPEKRWNITQI
|.. ... |. . . ... .|.. . ..|||| .| ||
MCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQI
Kinase 91566.m00136.AA Pkinase_Tyr 1-40 27 0.366547 4.56 Pfam 82-125 (270) Show / Hide 
Range on Protein: 1-40
Range on HMM: 82-125/270
Sequence Identity: 27% (12 aa)

MFVILEYCSNGSVLDLLLK----QNQLSGRKILTIVSQLAAAIE
.....||. .|. || | |    ...|.   .| .  | |.. |
IYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGME
Kinase 91566.m00136.AA Pkinase_Tyr 143-176 32 1.044307 3.02 Pfam 237-270 (270) Show / Hide 
Range on Protein: 143-176
Range on HMM: 237-270/270
Sequence Identity: 32% (11 aa)

IPEETPHELIEIIKHSMIRDPEKRWNITQITNYL
.|| .| |. ...|. .  |||.|   ..| . |
CPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL