Gene 91227.m00021 (T.vaginalis)

91227.m00021

Species: T.vaginalis
Alias: 91227.m00021, TvagK0552
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag2

Sequence

Name Sequence Type Origin Length Description Download
91227.m00021.AA Protein None 178 None Fasta, JSON
91227.m00021.kin_dom Protein Kinase Domain None 137 None Fasta, JSON

Protein domain

Protein domains of 91227.m00021.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 91227.m00021.AA Ciliate-E2-Unclassified 1-116 23 1.2e-26 89.49 In-house 176-347 (352) Show / Hide 
Range on Protein: 1-116
Range on HMM: 176-347/352
Sequence Identity: 23% (41 aa)

MFDRDL---HPKIIDFGFCREKGQN------------------LSTYCGTELFM----APEIICGKSYDG---QKAYIWAFGVTIHALATNQVPFDYANE
.|| .    ..||||||.... .||                  ..| |||  .|    |||...|. ||.    |. ||..|| .... ... ||.. |.
LFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNC

AL----------------LINDIKNNQL------------KLDIKAQGLLGWICKNSLQINPEERLTAAQIL
                  |...||....            ... .|. ..  ...  |. ||..|.|. |||
EQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQIL
Kinase 91227.m00021.AA CAMKL 1-116 32 3.3e-25 77.27 In-house 159-292 (297) Show / Hide 
Range on Protein: 1-116
Range on HMM: 159-292/297
Sequence Identity: 32% (46 aa)

MFDRDL--HPKIIDFGFCRE---K----GQNLSTYCGTELFMAPEIICG--KSYDGQKAYIWAFGVTIHALATNQVPFDYA--------NEALLINDIKN
..| .     |||||||. .   .    || |.| ||.  .|||||. |  |.|||.|. ||. ||.  |. . ..||| .        |  .| . |. 
LLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMC

NQLKLD----I-KAQGLLGWICKNSLQINPEERLTAAQIL
   . .    .  .. |. ..    || |||.| |. ||.
G-YYPPIWYHVSDCRDLIRKM----LQVNPEKRPTIHQIM
Kinase 91227.m00021.AA CAMK 9-117 20 9.5e-23 69.5 In-house 236-421 (425) Show / Hide 
Range on Protein: 9-117
Range on HMM: 236-421/425
Sequence Identity: 20% (39 aa)

KIIDFGFCREK--------------------------GQNLSTYCGTELFMA-PEIICG-------------KSYDGQKAYIWAFGVTIHALATNQVPFD
||||||| ...                          || ..|.|||  .|| ||.. |             | |.|.|. .|. ||   .. .   ||.
KIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFY

YA-------------NEALLINDIKNNQLKLDIK----------------------------AQGLLGWICKNSLQINPEERLTAAQILD
               |.  |   |.. .   . .                            .. |. ..    || .||.|.|..|.|.
GDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKM----LQVDPEKRMTIEQCLN
Kinase 91227.m00021.AA Ciliate-E2 1-117 21 1.9e-21 70.36 In-house 193-361 (365) Show / Hide 
Range on Protein: 1-117
Range on HMM: 193-361/365
Sequence Identity: 21% (40 aa)

MFDRDLHPKIIDFGFCREKGQN----------------------------------LSTYCGTELFMAPEIICGKSYDG--------QKAYIWAFGVTIH
.|     .||||||....  ..                                    |.|||  .|||||. ||.||.         |. ||..||...
LF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILY

ALATNQVPFDYANEALLINDIKNNQLKLDIK-------AQGLLGW------------ICKN----SLQINPEERLT-AAQILD
 . ... ||        .. ||....... .          ...|            ..|.     || .||.|.| . |||.
EMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCI-QCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN
Kinase 91227.m00021.AA Pkinase 1-118 23 1.3e-20 73.91 Pfam 140-290 (293) Show / Hide 
Range on Protein: 1-118
Range on HMM: 140-290/293
Sequence Identity: 23% (37 aa)

MFDRDLHP----KIIDFGFC----REKGQNLSTYCGTELFMAPEIICGKSYDGQKAYIWAFGVTIHALATNQVPFDYA------NEALLINDIKNNQLKL
..|.. |.    ||.|||..      ... ..|.|||  .||||.| | .|.|.|. .|..|.... ... . ||. .      ..  .|. |.  .|. 
LIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHF

D-------------------------IKAQGLLGWICKNSLQINPEERLTAAQILDY
|                           .. .. |.    |. .|..|.||.|||  
DWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWC----LCKDPKKRPTAEQILQH
Kinase 91227.m00021.AA MARK 9-116 36 3.1e-20 63.0 In-house 146-257 (262) Show / Hide 
Range on Protein: 9-116
Range on HMM: 146-257/262
Sequence Identity: 36% (42 aa)

KIIDFGFCREK--GQNLSTYCGTELFMAPEIICGKSYDGQKAYIWAFGVTIHALATNQVPFD--YANEALLINDIKNNQLK----LDIKAQGLLGWICKN
|||||||...   || |.| |||  .|||||. .| |||.|. ||. ||   .. . ..|||   ...  |   | . . .    .  ... |. ..   
KIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRL---

SLQINPEERLTAAQIL
 |..||||| |. .|.
-LTVNPEERPTIEEIM
Kinase 91227.m00021.AA MELK 1-121 30 5e-16 50.98 In-house 129-254 (254) Show / Hide 
Range on Protein: 1-121
Range on HMM: 129-254/254
Sequence Identity: 30% (39 aa)

MFDRDLHPKIIDFGFC-REKGQ----NLSTYCGTELFMAPEIICGKSYDGQKAYIWAFGVTIHALATNQVPFDYANEALLINDIKNNQLKLDIKAQGLLG
.|| |.| |.||||.| . ||.    || | ||   . |||.| ||.| |  | .|. |. . .|    .|||  |  ..   |     .       .  
LFDEDHHLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFLPFDDDNMMIMYKKIMSGCYEEPKWLSPESK

WICKNSLQINPEERLTAAQILDYAKS
 . .. ||..|. |.   ..|.    
QLLRHMLQVDPKKRISMKNLLNHPWV
Kinase 91227.m00021.AA RSK 1-117 23 1.8e-14 49.58 In-house 136-274 (278) Show / Hide 
Range on Protein: 1-117
Range on HMM: 136-274/278
Sequence Identity: 23% (34 aa)

MFDR---DLHPKIIDFGFCRE----KGQNLSTYCGTELFMAPEIIC---GKS-YDGQKAYIWAFGVTIHALATNQVPFDY---ANEALLINDIKNNQ--L
..|    . | |..|||||..    ..| . |.|.|  .||||..    ... .| . . .| .|| .. . | ..||     .| . ... |....  |
LYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHD-KACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSL

KLD------IKAQGLLGWICKNSLQINPEERLT-----AAQILD
...        |. |. .     |. .|. ||.     |..|..
TMPNWQYLSQEAKDLIRKM----LHRDPHKRLGCGPQDAEEIKQ
Kinase 91227.m00021.AA CAMK-Unique 9-117 22 3.1e-14 43.19 In-house 213-359 (363) Show / Hide 
Range on Protein: 9-117
Range on HMM: 213-359/363
Sequence Identity: 22% (33 aa)

KIIDFGFCREKGQNLST-----YCGTELFMAP--------------EIICGKSYDGQKA---YIWAFGVTIHALATNQVPFDYANEA--------LLIND
|..||| |... .| .      .|||...|||              |.| .  ||.|      ||. ||. . ...   ||| ..|.         ..  
KLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDRDYENHDKEIFEC

IKNNQL-KLDIKAQGL-------LGWICKNSLQINPEERLTAAQILD
|.  .. ..| |. ..       .  . |. ... |  |..|...|.
ICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLE
Kinase 91227.m00021.AA ULK 7-87 25 3.4e-14 46.04 In-house 180-290 (329) Show / Hide 
Range on Protein: 7-87
Range on HMM: 180-290/329
Sequence Identity: 25% (29 aa)

HPKIIDFGFCREKGQN------LSTYC------GTELFMAPEIIC----GKSYDGQKAYIWAFGVTIHALATNQVPF--DYANEAL------LIND----
. || ||||..    .      . |.       || |.|||.|.     .| |.  |. || .|. .. . ....||    .|.        |||.    
VLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPW

---IKNNQLKLD
   ||...|. .
PQQIKKQPLQFP
Kinase 91227.m00021.AA ULK 7-89 26 7.6e-14 45.57 In-house 176-287 (324) Show / Hide 
Range on Protein: 7-89
Range on HMM: 176-287/324
Sequence Identity: 26% (30 aa)

HPKIIDFGFCREKG------QNLSTYC------GTELFMAPEIIC----GKSYDGQKAYIWAFGVTIHALATNQVPF--DYANEAL-----LIND-----
. || ||||..         | . |..      || |.|||.|.     .| |.  |. || .|. .. . ....||  . .|.       |||      
VLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQ

--IKNNQLKLDIK
  |||.... ...
IYIKNQPIQFPKP
Kinase 91227.m00021.AA S_TKc 1-119 12 0.000105 -107.9 SMART 18-231 (231) Show / Hide 
Range on Protein: 1-119
Range on HMM: 18-231/231
Sequence Identity: 12% (29 aa)

MFDRD---------------------------------------------------------LHP-----------------------------------
  ...                                                         ..                                    
CRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPEHARFYMYQICCALEYCHSHGIIH

--------------KIIDFGFCREKGQNLSTYCGTELFMAPEIICGKSYDGQKAYIWAFGVTIHALATNQVPFDYANEALLINDIKNNQLKLDIKAQGLL
              ||.|||..|.     .|.|||  .||||..   .|.. |. .|..|...  ... . ||.  ....... |.          . ..
RDLKPENILLDEHIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG---------SPEAK

GWICKNSLQINPEERLTAAQILD---------YA
  . .. || .||.|.|| ..|          . 
D-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF