Gene 90492.m00307 (T.vaginalis)

90492.m00307

Species: T.vaginalis
Alias: TvagK0927, 90492.m00307
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: AMPK

Sequence

Name Sequence Type Origin Length Description Download
90492.m00307.AA Protein None 308 None Fasta, JSON
90492.m00307.kin_dom Protein Kinase Domain None 176 None Fasta, JSON

Protein domain

Protein domains of 90492.m00307.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 90492.m00307.AA AMPK 105-176 43 6.3e-35 101.18 In-house 183-254 (254) Show / Hide 
Range on Protein: 105-176
Range on HMM: 183-254/254
Sequence Identity: 43% (31 aa)

VWRCGIILYRLLTGNFPFEDDSKSELFTNILSMKPIIPSQISNDAKSLLKRMLTKDPYERITLEEIVEHPFF
.| ||.||| .| |  ||.|.. ..|. .|.. .. ||. .|..||.|.|.||..|| .||| ..|..||.|
IWSCGVILYAMLCGYLPFDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 90492.m00307.AA AGC 109-176 27 2.9e-34 84.73 In-house 292-395 (395) Show / Hide 
Range on Protein: 109-176
Range on HMM: 292-395/395
Sequence Identity: 27% (29 aa)

GIILYRLLTGNFPFEDDS----------KSELFTNIL------SMKPIIP----------SQISNDAKSLLKRMLTKDPYERIT----------LEEIVE
|...| .|||  || .|.          . |.| .|.      . |. .|          ...|..||.|.|..|.||| .|..           ||| .
GCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKN

HPFF
||.|
HPWF
Kinase 90492.m00307.AA Ciliate-E2-Unclassified 1-176 22 1.6e-28 96.06 In-house 100-352 (352) Show / Hide 
Range on Protein: 1-176
Range on HMM: 100-352/352
Sequence Identity: 22% (56 aa)

MEYLSDKNLEEYITNKKD-----------------INEDQVR-----VWFSEMILTLLYLDSSFQVCHNYLEASNFSLSNNG---HLKLFDFENCQFLDT
|||. ...|..||...|                  . | |..      .| . .. | || ..  ..|  .  .|  ..|||   ..|. || .. ....
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

A----------------MNSQVKKCHPFYL----SPEEIKNETNP----FTLTVWRCGIILYRLLTGNFPFEDDSKSE----------------LFTNIL
                 .... . . | |.    .|| .... .     .   .| .|.||| .|.|..||.| .. .                |. ||.
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

SM------KPI--IPSQISNDAKSLLK----RMLTKDPYERITLEEIVEHPFF
         |   || ..|. || ...    .|| |.| .|||.|.| .||.|
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 90492.m00307.AA CAMKL 105-176 29 2.2e-28 87.56 In-house 219-297 (297) Show / Hide 
Range on Protein: 105-176
Range on HMM: 219-297/297
Sequence Identity: 29% (24 aa)

VWRCGIILYRLLTGNFPFEDDS---------KSELFTNILSMKPIIPSQISNDAKSLLKRMLTKDPYERITLEEIVEHPFF
.| ||.||| ...|..||.||.         . .. ....  .| |....| |...|...||...| .|.|...|..||..
IWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 90492.m00307.AA MARK 105-176 40 1.7e-27 87.09 In-house 189-262 (262) Show / Hide 
Range on Protein: 105-176
Range on HMM: 189-262/262
Sequence Identity: 40% (30 aa)

VWRCGIILYRLLTGNFPFEDDS--KSELFTNILSMKPIIPSQISNDAKSLLKRMLTKDPYERITLEEIVEHPFF
.| .|..|| ...|.|||..|.    ||. .||. |. ||. .| ....|..|.|| .| ||.|.|||..||..
IWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 90492.m00307.AA CAMK 54-176 20 4.2e-27 83.78 In-house 228-425 (425) Show / Hide 
Range on Protein: 54-176
Range on HMM: 228-425/425
Sequence Identity: 20% (41 aa)

FSLSNNGHLKLFDFENCQFLDT------------------------AMNSQVKKCHPFYLS-PEEIKNET--------------NPFTLTVWRCGIILYR
| ..||. .|. ||   ...|                             .     | | . || .. ..               ..   .| ||.||| 
F-DWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYI

LLTGNFPFEDD-------------SKSELFTNILSMKPI-IPSQ---------------ISND--------AKSLLKRMLTKDPYERITLEEIVEHPFF
.|.| .||..|             . .||| .|.. |   .|..               ||..        .|.|...||..|| .|.|.|.. .||..
MLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 90492.m00307.AA SAK 9-176 30 6.8e-25 81.49 In-house 86-254 (254) Show / Hide 
Range on Protein: 9-176
Range on HMM: 86-254/254
Sequence Identity: 30% (51 aa)

LEEYITNK-KDINEDQVRVWFSEMILTLLYLDSSFQVCHNYLEASNFSLSNNGHLKLFDFENCQFLDTAMNSQVKKC-HPFYLSPEEIKNETNPFTLTVW
.. |. .. .   |.  |  . ...  .|||  |  . |  |  ||  |. . |.|. ||     |       .  |  | |.||| .   .      ||
MHRYMKHRMRPFTEEEARHFMHQIVIGMLYLH-SHGIMHRDLTLSNILLTRDMHCKIADFGLATQLKMPHEKHYTMCGTPNYISPEIATRTAHGLQSDVW

RCGIILYRLLTGNFPFEDDSKSELFTNILSMKPIIPSQISNDAKSLLKRMLTKDPYERITLEEIVEHPFF
  | .|| ||.|  ||. |.  .    ..    |.|. .| .|. |...|| |.| |||||. .. ||| 
SLGCMLYTLLIGRPPFDTDAVKNTLNKVMMAEYIMPAHLSMEAQDLIHKMLRKNPHERITLSTVLCHPFM
Kinase 90492.m00307.AA MELK 1-176 29 6.1e-24 78.44 In-house 76-254 (254) Show / Hide 
Range on Protein: 1-176
Range on HMM: 76-254/254
Sequence Identity: 29% (53 aa)

MEYLSDKNLEEYITNKKDINEDQVRVWFSEMILTLLYLDSSFQVCHNYLEASNFSLSNNGHLKLFDFENCQFLDTAMNSQ-VKKC--HPFYLSPEEIK-N
||| .  .. .||  .. ..|.. |. | ...  . |. |     |  |   |. . .. |||| ||  |      ..   .. |   | |  || |.  
MEYCPGGEMFDYIIRQDRLEEEETRHFFRQIVSAIAYVHSQ-GYAHRDLKPENLLFDEDHHLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQGK

ETNPFTLTVWRCGIILYRLLTGNFPFEDDSKSELFTNILSMKPIIPSQISNDAKSLLKRMLTKDPYERITLEEIVEHPFF
.       ||  ||.|| |. |  ||.||  . ..  |.| .   |  .|  .| ||..||  ||  || . ....||. 
QYIGSEADVWSMGILLYVLMCGFLPFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV
Kinase 90492.m00307.AA Ciliate-E2 1-176 20 1.2e-23 78.0 In-house 113-365 (365) Show / Hide 
Range on Protein: 1-176
Range on HMM: 113-365/365
Sequence Identity: 20% (55 aa)

MEYLSDKNLEEYITNK-----------KDINEDQVR---------------VWFSEMILTLLYLDSSFQVCHNYLEASNFSLSNNGHLKLFDFENCQFLD
|||.. ..|..|| |.           | ..| ...                .. ..|| | || |   ..|  .  .|  .     .|. || .....|
MEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYD

T----------AMNSQVKK-----------------------CHPFYLSPEEIKNET---------NPFTLTVWRCGIILYRLLTGNFPFEDDSKSELFT
.          . . .  |                       . | |..|| ....            .   .| .|.|||..|.|..||        . 
DDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------QQ

NILSMKPIIP------------------SQISNDAKSLLKR----MLTKDPYERIT-LEEIVEHPFF
.|.  |  .|                   ..|...| |.|.    || ||| .|||  |.| .||.|
QIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 90492.m00307.AA Pkinase 86-176 24 1.3e-23 84.52 Pfam 175-293 (293) Show / Hide 
Range on Protein: 86-176
Range on HMM: 175-293/293
Sequence Identity: 24% (29 aa)

PFYLSPEEIK-NETNPFTLTVWRCGIILYRLLTGNFPFEDD------SKSELFTNILSMKPIIPSQIS---------------------NDAKSLLKRML
|.|..|| |. ..  .    .| ||.||| .|.|..|| ..      .. ... .|.. ..  ... .                      ..|...|..|
PWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCL

TKDPYERITLEEIVEHPFF
.|||..|.| |.|..||.|
CKDPKKRPTAEQILQHPWF
Kinase 90492.m00307.AA RSK 109-176 32 7.4e-23 80.61 In-house 199-278 (278) Show / Hide 
Range on Protein: 109-176
Range on HMM: 199-278/278
Sequence Identity: 32% (26 aa)

GIILYRLLTGNFPFED---DSKSELFTNILSMK--PIIP--SQISNDAKSLLKRMLTKDPYERIT-----LEEIVEHPFF
|...| .|||. ||     ....|....|.. |  . .|  . .|..||.|...||..||  |..     .||| .||.|
GVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 90492.m00307.AA S_TKc 1-176 18 6.5e-10 -31.54 SMART 1-231 (231) Show / Hide 
Range on Protein: 1-176
Range on HMM: 1-231/231
Sequence Identity: 18% (48 aa)

M-----------------------------------------------------------------EYLSD--KNLEEYITNKKD------INEDQVRVW
                                                                  ||..    .| .|| ...       ..| ..| .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFY

FSEMILTLLYLDSSFQVCHNYLEASNFSLSNNGHLKLFDFENCQFLDTAMNSQVKKCHPFYLSPEEIKNETNPFTLTVWRCGIILYRLLTGNFPFEDDSK
. .... | |. |  ...|  |  .|  |..  |.|. ||  . .|            |.|..|| .    ...   .| ||.||| .|.|  ||.    
MYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYEMLCGYPPFP--QM

SELFTNILSMKPIIPSQISNDAKSLLKRMLTKDPYERITLEEIVE-------HPFF
 ..| .|.          | .||......|.||| .|.|  |. .       ||.|
QMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 90492.m00307.AA CAMK 1-38 18 0.004492 4.95 In-house 136-195 (425) Show / Hide 
Range on Protein: 1-38
Range on HMM: 136-195/425
Sequence Identity: 18% (11 aa)

M---EYLSDK----NLEEYITNKKD---------------INEDQVRVWFSEMILTLLYL
|   || |       | .||. ...               ..|...| .|  ..  . |.
MEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYC
Kinase 90492.m00307.AA CAMKL 1-32 26 0.02444 3.1 In-house 100-137 (297) Show / Hide 
Range on Protein: 1-32
Range on HMM: 100-137/297
Sequence Identity: 26% (10 aa)

MEYLSDKN--LEEYITNKKD----INEDQVRVWFSEMI
||| |  .  | .|| ....    . |.. |  |  ..
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIV
Kinase 90492.m00307.AA MARK 1-32 29 0.058462 2.39 In-house 81-114 (262) Show / Hide 
Range on Protein: 1-32
Range on HMM: 81-114/262
Sequence Identity: 29% (10 aa)

MEYLSDKNLEEYITNK--KDINEDQVRVWFSEMI
||| | ..| .|| ..    . |.  |. |. ..
MEYASGGELYDYIKAHPNGRLHEEEARRIFRQIV
Kinase 90492.m00307.AA Pkinase 1-38 19 0.485447 4.76 Pfam 79-124 (293) Show / Hide 
Range on Protein: 1-38
Range on HMM: 79-124/293
Sequence Identity: 19% (9 aa)

MEYLSDK----NLEEYIT--NKKDI--NEDQVRVWFSEMILTLLYL
|||.        | .||.  ... .   |.... .. ...  | |.
MEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYC
UBA_CAMKL 90492.m00307.AA UBA_CAMKL 194-229 25 0.000616 12.55 In-house 3-41 (41) Show / Hide 
Range on Protein: 194-229
Range on HMM: 3-41/41
Sequence Identity: 25% (10 aa)

DIIKQLEGS--GYNKATVIADLKAKLF-TEKTAAYNILL
.||....    |...  .|  |.   .  . ||.| .||
EIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL