Gene 84370.m00111 (T.vaginalis)

84370.m00111

Species: T.vaginalis
Alias: 84370.m00111, TvagK0171
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
84370.m00111.AA Protein None 219 None Fasta, JSON
84370.m00111.kin_dom Protein Kinase Domain None 177 None Fasta, JSON

Protein domain

Protein domains of 84370.m00111.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 84370.m00111.AA CAMK 1-174 18 2.8e-40 127.0 In-house 136-421 (425) Show / Hide 
Range on Protein: 1-174
Range on HMM: 136-421/425
Sequence Identity: 18% (53 aa)

M---EYCSGG----S-LQYLIDHSKPT-----------DDM-ETK-IKYVHEIIEAINYMHERSFAHCDIKPSNILIDQF-----------------GRA
|   ||||||      ..|...|....             . |    .|.. |..|..|.|..  .|.|.|| |||.|.                  .  
MEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNI

KLADFGLTHFVGSSG----------------------QDAKITYSGSFSYMS-PELLKY-------------RKCDPFKADVWAFGVTLYTLFGKHHPFR
|..|||.  .. ..                        .   |. |. .||. ||.|..             .. ...|.|.|. || ||..   . ||.
KIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFY

GK-------------TMETIICQMQAGII--PLKNIPH-----------------------DLGNIIEGCLKYKANERMTISQIKA
|.             ... .  . ..|    | . ...                       .  . | ..|..  ..||||.|...
GDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLN
Kinase 84370.m00111.AA TKL 1-176 19 8.5e-40 138.54 In-house 117-364 (364) Show / Hide 
Range on Protein: 1-176
Range on HMM: 117-364/364
Sequence Identity: 19% (50 aa)

MEYCSGGS-LQYLIDHSKPTDDMETKIKYVHEIIEAINYMHE--------RSFAHCDIKPSNILIDQFGR--------------AKLADFGLTHFVGSSG
||||.||| | ||.        .. ... ...|  ..||.|         .  .|.|.|..|||.|. ..              .|..||||  |.  ||
MEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSG

QDAKITY------------------SGSFSYMSPELLKYR---------------KCDPFKADVWAFGVTLYTLFGKHHPFRGKTMETIICQ-------M
.. .. .                   |.. .|.||.|.                 .    |.||..||. |. ..   .|...  ....|.|       |
NMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFM

QAG------IIP-----------LKNIPHDLGNIIEGCLKYKANERMTISQIKAEF
...       ||            ...|... .... | ......| . ..|. ..
MVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Pkinase 84370.m00111.AA Pkinase 1-176 24 3.6e-39 139.58 Pfam 79-293 (293) Show / Hide 
Range on Protein: 1-176
Range on HMM: 79-293/293
Sequence Identity: 24% (53 aa)

MEYCSGG----SLQYLID-HSKPTD--DMETKIKYVHEIIEAINYMHERSFAHCDIKPSNILIDQFGRA----KLADFGLTHFV-GSSGQDAKITYSGSF
|||| ||    .|  .|  ... .   .... ..|. .|.....|.|.... |.|.||.|||||. |      |..||||  ..   ...    |. |. 
MEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTP

SYMSPELLKYRKCDPFKADVWAFGVTLYTLFGKHHPFRGK------TMETIICQMQAGIIPLK----------------------NIPHDLGNIIEGCLK
 ||.||... .. .. |.|.|..|..|| .. .. ||.|.      ..  .||.   ....                        |.. ..  .|..||.
WYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLC

YKANERMTISQIKAE--F
.. ..| |. ||.    |
KDPKKRPTAEQILQHPWF
Kinase 84370.m00111.AA CAMKL 1-173 30 5.3e-36 112.27 In-house 100-292 (297) Show / Hide 
Range on Protein: 1-173
Range on HMM: 100-292/297
Sequence Identity: 30% (59 aa)

MEYCSGG---SLQYLIDHS---KPTDDMETKIKYVHEIIEAINYMHERSFAHCDIKPSNILIDQFG--RAKLADFGLTHFVGS--SG-QDAKITYSGSFS
|||||||    ..|.. |    .. .  |.. .|   |..|.||.|..  .| |||| |||.|. |   .|..|||.  .      |  .   |  || .
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEAR-RYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPP

YMSPELLKY--RKCDPFKADVWAFGVTLYTLFGKHHPFRGKTM--------ETIICQMQAGIIPL--KNIPHDLGNIIEGCLKYKANERMTISQIK
||.||...   .. | .|.|.|. ||.||..   . ||.. |.        .    .|.    |   . .. |. ..| . |. . ..|.|| ||.
YMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIM
Kinase 84370.m00111.AA Ciliate-E2 1-173 20 1.5e-31 105.55 In-house 113-360 (365) Show / Hide 
Range on Protein: 1-173
Range on HMM: 113-360/365
Sequence Identity: 20% (53 aa)

MEYCSGGSLQYLI---DHSKPTD-------DMETKIKYVHEIIE---------------AINYMHERS-FAHCDIKPSNILIDQFGRAKLADFGLTHFVG
||||.||.|...|   .....         ...  ...  .|..               |..|.|..    | ||||.|||.      |..||||  .. 
MEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYD

SS---------------GQDAKITYS---------------GSFSYMSPELLKYRKCDP--------FKADVWAFGVTLYTLFGKHHPFRGKTMETIICQ
 .               ..| ..|..               |.  ||.|| |.. | |         .|.|.|..||.|| .  . .||        . |
DDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQ

MQAGIIP-------------------LKNIPHDLGNIIEG----CLKYKANERMT-ISQIK
 . . |                     |... .  ..|      .|... ..|.| ..||.
IKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQIL
Kinase 84370.m00111.AA Ciliate-E2-Unclassified 1-173 24 8.5e-31 104.07 In-house 100-347 (352) Show / Hide 
Range on Protein: 1-173
Range on HMM: 100-347/352
Sequence Identity: 24% (60 aa)

MEYCSGGSLQYLIDHSKP-----------------TDDMETKI----KYVHEIIEAINYMHERS-FAHCDIKPSNILIDQFG---RAKLADFGLTHFVGS
|||| ||.|.. | ..|                   .. ..|     .|  .|.....|.|.   . | ||||.|||.|. |   . |..|||.  . ..
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

S--------------GQDAKITYSGSFSYM----SPELLKYRKCDP---FKADVWAFGVTLYT-LFGKHHPFRGKT-------------------METII
.               |.   | .|. .||    .||.|.  . |    .|.|.|..|| ||  |||. .|| ...                   .. .|
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGY-YPFYDNNCEQHQQLITQWINNAYRKQLYQNI

CQMQAGIIPLKN--IPHDLG--------NIIEGCLKYKANERMTISQIK
.| .  . . ..  ||...         ...  .||.. |.|.|..||.
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQIL
Kinase 84370.m00111.AA ULK 1-178 21 7.2e-29 97.95 In-house 99-329 (329) Show / Hide 
Range on Protein: 1-178
Range on HMM: 99-329/329
Sequence Identity: 21% (49 aa)

MEYCSGGSLQYLIDHSKPTDDMET----------KIKYVHEIIEAINYMHERSFAHCDIKPSNILIDQF------------GRAKLADFGLTHFVGSS--
|||| || |. .| . . .  ..|           |.. . |...  ..|..   |.||||.||||.              |..|.||||.  .| ..  
MEYCNGGDLEQYI-KKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNM

GQDAKITYS------GSFSYMSPELLKYR--KCDPF-K-ADVWAFGVTLYTLFGKHHPFRGKTMETII---CQMQAGI----------IPLK--------
 |.   |..      |.  ||.|..|. .  ....  . .|.| .|. .| .     ||..   .. .   .|    .          .||.        
EQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDP

NIPHDLGNIIEGCLKYKANERMTISQIKAEFPT
.|  .. ..| ..|.|. ..|... .. . .  
QISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 84370.m00111.AA ULK 1-178 21 9.3e-29 99.19 In-house 96-324 (324) Show / Hide 
Range on Protein: 1-178
Range on HMM: 96-324/324
Sequence Identity: 21% (49 aa)

MEYCSGGSLQYLIDHSKPTDDMETK-----------IKYVHEIIEAINYMHERSFAHCDIKPSNILIDQF------------GRAKLADFGLTHFVGS--
|||| || |. .|   |.   .| .           |.. . |...  ..|..   |.||||.||||               |..|.||||.  .| .  
MEYCNGGDLEQYIKKNKKL--PE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNN

SGQDAKITYS------GSFSYMSPELLKYR--KCDPF-K-ADVWAFGVTLYTLFGKHHPFRGKTMETII--------------CQMQAGIIPLK---NIP
  |.   |.       |.  ||.|..|. .  ....  . .|.| .|. .| .     ||..   .. .               ...   |. .   ..|
MEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDP

H---DLGNIIEGCLKYKANERMTISQIKAEFPT
.   .. ..| ..|.|. ..|... .| . .  
KISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 84370.m00111.AA STE 1-171 20 7.1e-26 88.41 In-house 116-350 (359) Show / Hide 
Range on Protein: 1-171
Range on HMM: 116-350/359
Sequence Identity: 20% (50 aa)

MEYCSGGSLQYLIDHSKPTDDM------------ETKI-KYVHEIIEA-INYMHERSFAHCDIKPSNILIDQFGRAKLADFGLTHFVGS-----------
|||..||||  .|.| . . ..            |. | .....|...  .| |.    | ||||.|||.     .||.|||.   . .           
MEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNII

----SGQDAKITYSGSFSYMSPELLKYRKCDPF------KADVWAFGVTLYTLFGKHHPF---RGKTMETIICQMQ-------------AGIIPLKN---
    ..|    |  |.  .|.|| .. ....        |.|.| .| |.  .   ..|.       .   | ...              .. ||..   
DCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-RDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLS

-----------------IPHDLGNIIEGCLKYKANERMTISQ
                    .. . |. ||..  |.| | ||
QNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ
Kinase 84370.m00111.AA TKL-Unique 1-127 26 3.4e-23 78.77 In-house 79-236 (290) Show / Hide 
Range on Protein: 1-127
Range on HMM: 79-236/290
Sequence Identity: 26% (42 aa)

MEYCSGGSLQYLID---------HSKPTDDMETKIKYVHEIIEAINYMHERS--FAHCDIKPSNILIDQF-----GRAKLADFGLTHFVGSSGQDAKI--
||||.||||  ...          .. . .|. ..| .. |  . .| | ..   .|.|.|.||.|.|..      ..|..||||  |  .. .  ..  
MEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEH

------TYSGSFSYMSPELLKYR-KCDPFKADVWAFGVTLYTLFGKHH------PFRG
      |  ||| .|.||.|.   .    |.||..||. |. ..  .       |..|
KGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQG
Kinase 84370.m00111.AA MARK 32-69 50 7.2e-17 51.83 In-house 193-232 (262) Show / Hide 
Range on Protein: 32-69
Range on HMM: 193-232/262
Sequence Identity: 50% (20 aa)

IIEAINYMHERSFAHCDIKPSNILIDQFG--RAKLADFGL
|..|.||.|... .|.|||| |||||. |   .|..|||.
IVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGF
Kinase 84370.m00111.AA MARK 86-172 28 7.3e-17 51.81 In-house 167-256 (262) Show / Hide 
Range on Protein: 86-172
Range on HMM: 167-256/262
Sequence Identity: 28% (26 aa)

GSFSYMSPELLKYRKCDPFKADVWAFGVTLYTLFGKHHPFRGKT--METIICQMQAGIIP-LKNIPHDLGNIIEGCLKYKANERMTISQI
|. .||.||...... | .|.|.|. || ||..   . ||.|.|  ....  ....|  .   ...... |.|   |.   .||.||..|
GTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEI
Kinase 84370.m00111.AA S_TKc 1-178 17 1.3e-15 52.0 SMART 1-231 (231) Show / Hide 
Range on Protein: 1-178
Range on HMM: 1-231/231
Sequence Identity: 17% (46 aa)

M-----------------------------------------------------------------EYCSG--GSLQYLIDHSKP-----TDDMETKIKY
                                                                  |||.|  |.|  .|.. ..       .  .  .|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFY

VHEIIEAINYMHERSFAHCDIKPSNILIDQFGRAKLADFGLTHFVGSSGQDAKITYSGSFSYMSPELLKYRKCDPFKADVWAFGVTLYTLFGKHHPFRGK
...|..|..|.|.. . |.|.||.|||.|.  . |..||||  ..         |. |.  ||.||.|   . ...|.|.|..|..|| ..    ||.  
MYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--

TMETIICQMQAGIIPLKNIPHDLGNIIEGCLKYKANERMTISQIKA-------EFPT
.|.... ..          .... ..|..||..  ..|.|. .. .           
QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 84370.m00111.AA Pkinase_Tyr 1-116 27 1.5e-10 36.37 Pfam 86-205 (270) Show / Hide 
Range on Protein: 1-116
Range on HMM: 86-205/270
Sequence Identity: 27% (33 aa)

MEYCSGGSL-QYLIDH--SKPTDDMETKIKYVHEIIEAINYMHERSFAHCDIKPSNILIDQFGRAKLADFGLTHFV--GSSG-QDAKITYSGSFSYMSPE
|||. .|.|  || .|  .|.  .|...... ..| .. .| ... . | |.   |.|..  . .| .||||.  .   .   . .. .       |.||
MEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPE

LLKYRKCDPFKADVWAFGVTLY
 ..|.|.   | |||.|||...
CINYGKFT-TKSDVWSFGVLMW
Kinase 84370.m00111.AA TyrKc 1-176 17 2.8e-08 -88.68 SMART 1-280 (280) Show / Hide 
Range on Protein: 1-176
Range on HMM: 1-280/280
Sequence Identity: 17% (50 aa)

M-----------------------------------------------------------------------------EYCSGGSL-QYLIDHSKPTDDM
                                                                              ||...|.| .|| .| .    |
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK-LCM

ETKIKYVHEIIEAINYMHERSFAHCDIKPSNILIDQFGRAKLADFGLTHFVGSS---GQDAKITYS-----GSFS-----YMSPELLKYRKCDPFKADVW
...... . | .  .| |.. . | |.   |.|..  ...| .||||. ....    |  .| .|.     |. .      |.|| ..|.|.  .| |||
KDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG-ESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-TKSDVW

AFGVTLYTLFGK-HHPFRG-----KTMETIICQMQAG--IIPLKN--------IPHDLGNIIEGCLKYKANERMTISQIKAEF
.|||... .|     |  |     .. . .| . ..|    . .|         | .. .|.. | ......| | |.|. .|
SFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF