Gene 81732.m00008 (T.vaginalis)
81732.m00008
Species: T.vaginalis
Alias: 81732.m00008, TvagK0147
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
---|---|---|---|---|---|
81732.m00008.AA | Protein | None | 128 | None | Fasta, JSON |
81732.m00008.kin_dom | Protein Kinase Domain | None | 99 | None | Fasta, JSON |
Protein domains of 81732.m00008.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Pkinase | 81732.m00008.AA | Pkinase | 1-91 | 35 | 1.5e-25 | 91.42 | Pfam | 79-182 (293) | Show / Hide |
Range on Protein: 1-91 Range on HMM: 79-182/293 Sequence Identity: 35% (38 aa) MEYCPS-----DLERVMK--QQKLF--SKEELLKYSKEVVQSVCACHSKNIAHCDIKPANFLVDKYGRL----KIGDFGLSSV--YDDQYTCDLFKGTII ||||. || .... ... | | .|. .| ..... . |||..| |.|.||.|.|.|. | . ||.||||. . | . .. | ||. MEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPW YMAPEV |||||| YMAPEV |
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Kinase | 81732.m00008.AA | AGC | 1-99 | 21 | 3.1e-25 | 60.82 | In-house | 112-282 (395) | Show / Hide |
Range on Protein: 1-99 Range on HMM: 112-282/395 Sequence Identity: 21% (37 aa) MEYCP---------SDLERVMKQQK-----LFSKEELLKYSKE-------VVQSVCACHS-KNIAHCD-IKPANFLVDKYGRLKIGDFGLSSV--YDD-- |||.| ..| . .|. |. |. | | .| . || ..| | | .|| | | |. | .|. ||||. . |. MEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEK -----------------------------------------------QYTCDLFKG--TIIYMAPEVFESEDYNP . .. | | | |||||.. |.. GQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGK |
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Kinase | 81732.m00008.AA | CAMK | 1-97 | 20 | 5.6e-24 | 73.53 | In-house | 136-310 (425) | Show / Hide |
Range on Protein: 1-97 Range on HMM: 136-310/425 Sequence Identity: 20% (36 aa) M---EYCPSD------LERVMKQ--------------QKLFSKEELLKYSKEVVQSVCACHSKNIAHCDIKPANFLVDKY-----------------GRL | |||. .... .. . |. .| .| . ... | |||.||.|.|.|| | |.|. . . MEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNI KIGDFGLSSVYDD------------------------QYTCDLFKGTIIYMA-PEVFES-------------EDY || |||.. ..|. . | || ||| |||... ..| KIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPY |
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Kinase | 81732.m00008.AA | Ciliate-E2 | 1-98 | 26 | 1.3e-21 | 70.95 | In-house | 113-265 (365) | Show / Hide |
Range on Protein: 1-98 Range on HMM: 113-265/365 Sequence Identity: 26% (42 aa) MEYCPS-DLERVMKQQKLFS-----------KEELLKYSKEVVQ---------------SVCACHSKN-IAHCDIKPANFLVDKYGRLKIGDFGLSSVYD |||| ||. .|..|... .| ....|...| . .|||| | | |||| | |. .|| ||||| || MEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYD DQ----------YTCDLFK-----------------------GTIIYMAPEVFESEDYN |. . . | || |||||......|. DDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYD |
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Kinase | 81732.m00008.AA | Ciliate-E2-Unclassified | 1-98 | 30 | 1.7e-21 | 71.35 | In-house | 100-244 (352) | Show / Hide |
Range on Protein: 1-98 Range on HMM: 100-244/352 Sequence Identity: 30% (44 aa) MEYCPS------------------DLERVMKQQKLFSKEELL-----KYSKEVVQSVCACHSKN-IAHCDIKPANFLVDKYG---RLKIGDFGLSSVYDD ||||. || . |||.| |. .. . .| ....| . .|.|| | | |||| | |.|. | ..|| |||.|. |.. MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ QYTCDLFK-----------------GTIIYM----APEVFESEDYN .. || .. ||..|| ||||.... |. NNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYD |
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Kinase | 81732.m00008.AA | ULK | 1-98 | 29 | 1.8e-21 | 71.8 | In-house | 99-233 (329) | Show / Hide |
Range on Protein: 1-98 Range on HMM: 99-233/329 Sequence Identity: 29% (40 aa) MEYCPS-DLERVMKQQKL----------FSKEELLKYSKEVVQSVCACHSKNIAHCDIKPANFLVDKY------------GRLKIGDFGLSSVYD-D--- ||||. ||| .|..| .| .| ... | .. . |..|| |.||||.| |... |.|||.|||.. . | | MEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNME ---QYTCD---LFKGTIIYMAPEVFE----SEDYN .|| ...|| .||||.... ..|. QQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYY |
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Kinase | 81732.m00008.AA | CAMKL | 37-98 | 40 | 3.6e-21 | 64.19 | In-house | 143-213 (297) | Show / Hide |
Range on Protein: 37-98 Range on HMM: 143-213/297 Sequence Identity: 40% (29 aa) CHSKNIAHCDIKPANFLVDKYG--RLKIGDFGLSSVYDD-----QYTCDLFKGTIIYMAPEVFES--EDYN |||..|.| |||| | |.|. | .|| |||.| |.. ... | |. |||||.|.. ..|. CHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYD |
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Kinase | 81732.m00008.AA | ULK | 1-98 | 29 | 1.1e-19 | 66.51 | In-house | 96-229 (324) | Show / Hide |
Range on Protein: 1-98 Range on HMM: 96-229/324 Sequence Identity: 29% (40 aa) MEYCPS-DLERVMKQQKL---------FSKEELLKYSKEVVQSVCACHSKNIAHCDIKPANFLVDKY------------GRLKIGDFGLSSVYDD----- ||||. ||| .|..| .| .| ... | .. . |..|| |.||||.| |. . |.|||.|||.. . |. MEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQ --QYTCD---LFKGTIIYMAPEVFE----SEDYN .|| . ||| .||||.... ..|. QMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYY |
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Kinase | 81732.m00008.AA | CMGC | 1-76 | 19 | 3.2e-19 | 58.98 | In-house | 134-283 (513) | Show / Hide |
Range on Protein: 1-76 Range on HMM: 134-283/513 Sequence Identity: 19% (29 aa) MEYCPSDLERVMKQQK---------LFSKEE------------LLKYS------KEVVQSVC--ACHSKN--IAHCDIKPANFLVD-------------- .||.. || ...|... .| . ... . . ... |||.. | |.|.||.| |.. FEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSE ------KYGRLKIGDFGLSSVYDDQ------------------------YT | |||||.||||. |.. || DWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYT |
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Kinase | 81732.m00008.AA | Ciliate-E3 | 1-68 | 41 | 5.6e-18 | 52.91 | In-house | 83-153 (202) | Show / Hide |
Range on Protein: 1-68 Range on HMM: 83-153/202 Sequence Identity: 41% (30 aa) MEYCPS-DLERVMKQQKLFSKEELLKYSKEVVQSVCACHSKNIAHCDIKPANFLVDKYG---RLKIGDFGLS .||| || .||| . ....... ....|.. | |.||| | |||| |.|||| .||.|||.| QEYCSNGDLYHYIKQQNK-TQNIIYDICIQIIQGMIAIHEKNIIHSDIKPDNILVDKNNNQLIIKICDFGES |
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Kinase | 81732.m00008.AA | TKL | 38-99 | 23 | 4.1e-16 | 54.53 | In-house | 149-252 (364) | Show / Hide |
Range on Protein: 38-99 Range on HMM: 149-252/364 Sequence Identity: 23% (24 aa) HS--------KNIAHCDIKPANFLVDKYGR--------------LKIGDFGLSSVYDDQYTCDL--------------------FKGTIIYMAPEVFESE || ..|.|.|.|..| |||. .. .||.||||| . . ||. .|||||.. . HSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQ DYNP .... MNYT |
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Kinase | 81732.m00008.AA | S_TKc | 1-125 | 15 | 3.2e-07 | -70.93 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 1-125 Range on HMM: 1-231/231 Sequence Identity: 15% (38 aa) M-----------------------------------------------------------------EYCPS---DLERVMKQQKL------FSKEELLKY |||. || ...|... |. . .| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFY SKEVVQSVCACHSKNIAHCDIKPANFLVDKYGRLKIGDFGLSSVYDDQYTCDLFKGTIIYMAPEVFESEDYNP------------------------IIV ..... . |||..| |.|.||.| |.|. ..||.||||. .. . | || ||||||. |.. . . MYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFPQMQM SIQVLG--------------MVALRSTLPNTCE-------FDTL ....| . | | . . MFKKIGSPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |