Gene 85337.m00288 (T.vaginalis)

85337.m00288

Species: T.vaginalis
Alias: 85337.m00288, TvagK0464
External Links:
Annotation:

Classification

Group: CK1
Family: CK1
Subfamily: CK1-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
85337.m00288.AA Protein None 266 None Fasta, JSON
85337.m00288.kin_dom Protein Kinase Domain None 179 None Fasta, JSON

Protein domain

Protein domains of 85337.m00288.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 85337.m00288.AA CK1 1-182 28 6.9e-55 188.67 In-house 108-339 (339) Show / Hide 
Range on Protein: 1-182
Range on HMM: 108-339/339
Sequence Identity: 28% (66 aa)

MEILGPSISNILK--LIHDNRFSFSTTIRTIYHMLKCIESFHIFGLIHRDIKPGNILTR-------EGHEH--------PLCLVDFGLSH-VYIDP----
|. |||... ..|     ...|| .|...  . ||. .|  |  | |||||||.|..         . | |         . ..|||...  |.|.    
MTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKH-HHEWNNEHRQVYMIDFGMARRKYRDKDGHN

-------NSGKILPPRK---RLGFRG-TKVYASIYAHQNEDLGRRDDLLSWFYVSMELLVGS--LPWRGKTDKYE-----ILQMKLNYNVQEAIGNKV--
       . ... |||.   . |||| |  |.|| .|.. ..|||||| ||||. .|.|.|.  |||.. .|. .     . .|| ..       ...  
RWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKMSTPFFL

----------PELVTIYNLLSRLSFADTPNYAQI
          .|. .|.. .. |.. |.|.|. |
CCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI
Kinase 85337.m00288.AA TTBKL 1-186 29 1.5e-46 155.2 In-house 79-288 (288) Show / Hide 
Range on Protein: 1-186
Range on HMM: 79-288/288
Sequence Identity: 29% (62 aa)

MEILGPSISNILKLIHDNR-FSFSTTIRTIYHMLKCIESFHIFGLIHRDIKPGNILT-REGH----EHPLCLVDFGLSHVYIDPNSG----------KIL
|. .||... . | .  .. || .|. |  .  |...   |  | ||||.||.|. .  ..|    .. . |.|||..  |......          .. 
MTLCGPNLQDLRKMMPNKKRFSDGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMR

PPRK---RLGFRGTKVYASIYAHQNEDLGRRDDLLSWFYVSMELLVGSLPWRGKTDKYEILQMKLNYNVQEAIGNKV------PELVTIYNLLSRLSFAD
.||.   . .||||  |.|...|.  ..|| ||| ||.|. .||..| |||.. .|| || .||.| . .   ...       .|.  ..  |..|...|
RPRNFRHKAPFRGTTRYCSPNMHDRKEQGRHDDLWSWMYMIIELHCG-LPWTNMEDKMEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYD

TPNYAQIYQLL
.|.|  ||...
RPDYEMIYECF
Kinase 85337.m00288.AA Worm6 1-182 30 3e-43 150.0 In-house 82-279 (279) Show / Hide 
Range on Protein: 1-182
Range on HMM: 82-279/279
Sequence Identity: 30% (60 aa)

MEILGPSISNILKLIHDNRFSFSTTIRTIYHMLKCIESFHIFGLIHRDIKPGNI-LTR-----EGHEHPLCLVDFGLSH--VYIDPNSGKILPPR-KRLG
|...|.. ... |   |..||..|...    .|. ||  | .| ||||.||||    |      . .| ....|||...  .|.. . ... .|| .. |
MTLVGKNLWDLRKNRPDRKFSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCN-KGNELRTPRWTACG

FRGTKVYASIYAHQNEDLGRRDDLLSWFYVSMELLVGSLPWRGKTDKYEILQMKLN--YNVQ----EAIGNKVP--ELVTIYNLLSRLSFADTPNYAQI
||||  ||.. .|.. ...|.||. ||||.  |..|| ||||. .|. .  . |    .. .    .   ...|  |.. |   .  .|. |.|.|..|
FRGTVRYAPLACHKGQEQCRKDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI
Kinase 85337.m00288.AA TTBK 1-182 37 1.7e-40 140.84 In-house 75-257 (257) Show / Hide 
Range on Protein: 1-182
Range on HMM: 75-257/257
Sequence Identity: 37% (69 aa)

MEILGPSISNILKLIHDNRFSFSTTIRTIYHMLKCIESFHIFGLIHRDIKPGNI-LTREGHEHPLC-LVDFGLSHVYIDPNSGKILPPRKRLGFRGTKVY
|...| . ..      .  || |||.|    .|. ||| |  |  |||||| |  . |   .   | ..||||   |.   .| . |||.  |||||  |
MQLQGKNLADLRRKQPRGCFSLSTTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQYTN-ACGEVRPPREVAGFRGTVRY

ASIYAHQNEDLGRRDDLLSWFYVSMELLVGSLPWRGKTDKYEILQMKLNYNVQEAIGNKVPELVTIYNLLSRLSFADTPNYAQI
||| ||.| ..||.||| | ||.  | ..| ||||   || .. .||  |. .  . .  .|. .  . .. | ..|.|.|. |
ASINAHRNREMGRHDDLWSLFYMLVEFVQGQLPWRKIKDKDQVGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI
Kinase 85337.m00288.AA CK1-D 1-182 35 6.8e-28 95.41 In-house 74-261 (261) Show / Hide 
Range on Protein: 1-182
Range on HMM: 74-261/261
Sequence Identity: 35% (67 aa)

MEILGPSISNILKLIHDNRFSFSTTIRTIYHMLKCIESFHIFGLIHRDIKPGNILTREGHE-HPLCLVDFGLSHVYIDPNSGKILPPRKRLGFRGTKVYA
|..||||.  .    |  .||. | .     |.. ||  |    ||||||| | |   |.  .   ..||||.  | |... . .| |      ||  ||
MDLLGPSLEDLFNYCH-RKFSLKTVLMLADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYA

SIYAHQNEDLGRRDDLLSWFYVSMELLVGSLPWRG-----KTDKYE-ILQMKLNYNVQEAIGNKVPELVTIYNLLSRLSFADTPNYAQI
||  ||  .  ||||| |  || |    ||||| |     | .||| | . |.. ....       | ..  |   .| | | |.|. .
SINTHQGIEQSRRDDLESLGYVLMYFNRGSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL
Kinase 85337.m00288.AA CK1-A 1-182 34 8e-27 91.72 In-house 74-261 (261) Show / Hide 
Range on Protein: 1-182
Range on HMM: 74-261/261
Sequence Identity: 34% (66 aa)

MEILGPSISNILKLIHDNRFSFSTTIRTIYHMLKCIESFHIFGLIHRDIKPGNILTREG-HEHPLCLVDFGLSHVYIDPNSGKILPPRKRLGFRGTKVYA
|..||||. ..  .  . ||.. | .     |.  ||  |  . ||||||| | |   | |   | |.||||.  | |... . .| |.     ||  ||
MDLLGPSLEDLFNFC-KRRFTMKTVLMLADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYA

SIYAHQNEDLGRRDDLLSWFYVSMELLVGSLPWRG-----KTDKYE-ILQMKLNYNVQEAIGNKVPELVTIYNLLSRLSFADTPNYAQI
|| ||.  .  ||||. |  || |    |.||| |     |  ||| |.  |.   ...       |.  . |    | | ..|.|  .
SINAHLGIEQSRRDDMESMGYVMMYFNRGKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL
Kinase 85337.m00288.AA CK1 32-180 37 8.4e-23 75.47 In-house 114-271 (271) Show / Hide 
Range on Protein: 32-180
Range on HMM: 114-271/271
Sequence Identity: 37% (60 aa)

MLKCIESFHIFGLIHRDIKPGNIL-TR-EGHEHPLCLVDFGLSHVYIDPNSGKILPPRKRLGFRGTKVYASIYAHQNEDLGRRDDLLSWFYVSMELLVGS
|.. || .|  ..||||||| |.|  | . |.| . ..||||.  |.|.....  | |   .. ||  |||| .|.    .||||. |  || | .| ||
MIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDMESLGYVLMYFLRGS

LPWRG-----KTDKYE-ILQMKLNYNVQEAIGNKVP-ELVTIYNLLSRLSFADTPNYA
||| |     | .||| |. .|....|..   .. | |...  |   .|.|...|.|.
LPWQGLKANTKKQKYEKIMEKKMSTPVEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM
Kinase 85337.m00288.AA CK1-Unclassified 32-154 42 5.4e-21 58.71 In-house 113-244 (244) Show / Hide 
Range on Protein: 32-154
Range on HMM: 113-244/244
Sequence Identity: 42% (56 aa)

MLKCIESFHIFGLIHRDIKPGNIL--TREGHEHPLCLVDFGLSHVYIDP-NSGKILPPRKRLGFRGTKVYASIYAHQNEDLGRRDDLLSWFYVSMELLVG
|.. || .|  ..||||||| |.|   .... | . ..|||||  |||. . ||  | |   .. ||  |||| ||.    .||||| |  || . .| |
MIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDMDKTGKHIPYRENKNLTGTARYASINAHLGIEQSRRDDLESLGYVLIYFLKG

SLPWRG-----KTDKYE-ILQMKLNYNVQEAI
|||| .     | .||| |. ||... |..  
SLPWQNIKANNKKEKYEKIMEMKMSTPVEQLC
Kinase 85337.m00288.AA CK1-G 1-182 32 1.1e-20 66.72 In-house 75-266 (266) Show / Hide 
Range on Protein: 1-182
Range on HMM: 75-266/266
Sequence Identity: 32% (63 aa)

MEILGPSISNILKLIHDNRFSFSTTIRTIYHMLKCIESFHIFGLIHRDIKPGNIL-TREG--HEHPLCLVDFGLSHVYIDPNSGKILPPRKRLGFRGTKV
|. ||||      .  | .||  |..     |.. .|  |   || ||.|| | |  |..  ..| . ..|||.   ||||. ..  | | .    ||  
MDLLGPSLEDLFDWC-DRKFSVKTVCMVAIQMIHRMEYVHSHHLIYRDVKPDNFLIGRPSNKDQHVIHIIDFGMAKQYIDPETKQHIPYREHKSLTGTAR

YASIYAHQNEDLGRRDDLLSWFYVSMELLVGSLPWRG-KTD----KYE-ILQMKLNYNVQEAIGN-KVP-ELVTIYNLLSRLSFADTPNYAQI
| ||  |      ||||. .   . |  | ||||| | | |    .|. | . | . |..  . |  .| .. |      ||.| ..| |  .
YMSINTHLGREQSRRDDMEALGHMFMYFLRGSLPWQGLKADNNKERYQKIGDTKRKTNIEDLCQNNAFPEQFATYLRYVRRLDFFECPDYDYL
Kinase 85337.m00288.AA CK1-Unique 1-133 30 1.7e-19 64.26 In-house 89-233 (337) Show / Hide 
Range on Protein: 1-133
Range on HMM: 89-233/337
Sequence Identity: 30% (44 aa)

MEILGPSISNILKLIHDNRFSFS------TTIRTIYHMLKCIESFHIFGLIHRDIKPGNILTREGH---EHPLCLVDFGLS-HVYIDPNSGKILPPRKRL
| ..|||.  .  .     |  .      . |.. |  |  ||  |  | .||..||.|. .       .| .   |.| .  | .  |.. | .||.. 
MTMHGPSMEECCMMMKNFQFTLNEKKNQLCAIQCGYQCLNVIECMHWHGFHHRHMKPNNYCYMAPSQQHQHCYYMLDYGICRRVFFVSNNHQIRQPRPIT

GFRGTKVYASIYAHQNEDLGRRDDLLSWFYVSMELLVGS--LPWR
 |||.| |...  || ...|||||. ||||  . |. .   | |.
PFRGCKDYCPCSCHQCREHGRRDDMESWFYMLYHLVHNTRGLSWK
Kinase 85337.m00288.AA Pkinase 40-100 31 2e-06 23.62 Pfam 125-179 (293) Show / Hide 
Range on Protein: 40-100
Range on HMM: 125-179/293
Sequence Identity: 31% (20 aa)

HIFGLIHRDIKPGNILTREGHEHP---LCLVDFGLSHVYIDPNSGKILPPRKRLGFRGTKVYAS
|  | ||||.|| |||    . |.   ... ||||. ..       . . .   .| ||  |..
HSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFD------Y-NNS-MTTFCGTPWYMA
Kinase 85337.m00288.AA S_TKc 1-191 13 4.3e-05 -102.21 SMART 1-231 (231) Show / Hide 
Range on Protein: 1-191
Range on HMM: 1-231/231
Sequence Identity: 13% (36 aa)

MEILGP-------------SIS----------------------------------------------------NILKLIHDNR-------FSFSTTIRT
 ||| .              ..                                                    . ...|....       |.  .. . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFY

IYHMLKCIESFHIFGLIHRDIKPGNILTREGHEHPLCLVDFGLSHVYIDPNSGKILPPRKRLGFRGTKVYASIYAHQNEDLGR-RDDLLSWFYVSMELLV
.| ... .|  |  | ||||.|| |||  |     . . ||||. ..                | ||  | .         |. . |  |   .  |.|.
MYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL--------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

GSLPWRGKTDKYEILQMKLNYNVQEAIGNKVPELVTIYNLLSRLSFADTPNYAQIYQLLD-------TAMK
|  |..   . ...... .                   ......   |  .   . ..|            
GYPPFP---QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF