Gene 94174.m00173 (T.vaginalis)

94174.m00173

Species: T.vaginalis
Alias: TvagK0563, 94174.m00173
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag2

Sequence

Name Sequence Type Origin Length Description Download
94174.m00173.AA Protein None 236 None Fasta, JSON
94174.m00173.kin_dom Protein Kinase Domain None 172 None Fasta, JSON

Protein domain

Protein domains of 94174.m00173.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase 94174.m00173.AA Pkinase 1-120 34 4.9e-37 132.02 Pfam 79-212 (293) Show / Hide 
Range on Protein: 1-120
Range on HMM: 79-212/293
Sequence Identity: 34% (47 aa)

MEFLENG----DMQTFIN--QEYTC--KPQEYIRIVSEILEALSYLHARGISHRDIKPANIMFDKNFHP----KRIDFGFC----RENSPKLKTYCGTDL
||..|.|    |  ..|   .. .    ..| .... .||..| |.|..|| |||.||.||..|.| |.    | .|||..      |.. ..|.|||  
MEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPW

LIAPEIMRHRCYDGEKADMWSFGVTAHIFVTRNLPF
 .|||. |.. |.| |.||||.|.. ........||
YMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPF
Kinase 94174.m00173.AA CAMK 1-121 24 6.5e-37 115.97 In-house 136-335 (425) Show / Hide 
Range on Protein: 1-121
Range on HMM: 136-335/425
Sequence Identity: 24% (49 aa)

M---EFLENG----DMQTFINQE---------------YTCKPQEYIRIVSEILEALSYLHARGISHRDIKPANIMFDKN-----------------FHP
|   |. ..|    |.  .| .                   . .|  |..  |..|. |.| ..| |||.|| ||..|.|                 .  
MEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNI

KRIDFGFCRENSP--------------------------KLKTYCGTDLLIA-PEIMRH-------------RCYDGEKADMWSFGVTAHIFVTRNLPFE
| ||||| ..  |                          |.||.|||   .| ||. .              . |.|.|.|||| ||   | ..  .||.
KIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFY
Kinase 94174.m00173.AA CAMKL 1-121 36 7.6e-33 102.04 In-house 100-237 (297) Show / Hide 
Range on Protein: 1-121
Range on HMM: 100-237/297
Sequence Identity: 36% (51 aa)

MEFLENGD--MQTFI--NQEYT--CKPQEYIRIVSEILEALSYLHARGISHRDIKPANIMFDKNF--HPKRIDFGFCRE---N----SPKLKTYCGTDLL
||  ..|.  .. .|  . .     .. |  |.   |..|..|.| .|| |||||| ||..|.|     | |||||. .   .      |||| ||.   
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

IAPEIMRH--RCYDGEKADMWSFGVTAHIFVTRNLPFE
 ||||     . ||| |.|.|| ||.    |. .|||.
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFD
Kinase 94174.m00173.AA Ciliate-E2-Unclassified 1-127 27 3.1e-31 105.58 In-house 100-277 (352) Show / Hide 
Range on Protein: 1-127
Range on HMM: 100-277/352
Sequence Identity: 27% (49 aa)

MEFLENGDMQTFINQEYT-----------------CKPQEYI-----RIVSEILEALSYLHARG-ISHRDIKPANIMFDKN---FHPKRIDFGFCR---E
||..|.||.. .|..  .                    |. .     ..  .||..|.|||  . | |||||| ||.||.|   ...| ||||...   .
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

N---------------SPKLKTYCGTDLLI----APEIMRHRCYDG---EKADMWSFGVTAHIFVTRNLPFEYKSDSQ
|               . ...| |||   .    |||...   ||.   .|.|.||.|| .. ... ..||..... |
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQ
Kinase 94174.m00173.AA Ciliate-E2 1-171 20 9.1e-31 102.83 In-house 113-362 (365) Show / Hide 
Range on Protein: 1-171
Range on HMM: 113-362/365
Sequence Identity: 20% (55 aa)

MEFLENGDMQTFINQEYTCKPQE----------YIR-IVSEILE---------------ALSYLHARG-ISHRDIKPANIMFDKNFHPKRIDFGFCRENS
||... ||.. .|.. ......|           |. |  .||.               || ||| .. | |||||| ||.|     .| ||||......
MEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYD

PK----------------------------------LKTYCGTDLLIAPEIMRHRCYDG--------EKADMWSFGVTAHIFVTRNLPFEYKSDSQYWKD
..                                   .|.|||    |||| .   ||.        .|.|.||.||. ..... ..||           
DDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF----------Q

VKNRTLKIE-NQAHGI-------IGW------------LVDQ----TVKINPDERME-AGELLEN
 ..   ||. .... .       ..|            |  .      . .|..|.  . ..|..
QQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNH
Kinase 94174.m00173.AA MARK 31-108 48 1.3e-27 87.5 In-house 113-194 (262) Show / Hide 
Range on Protein: 31-108
Range on HMM: 113-194/262
Sequence Identity: 48% (40 aa)

ILEALSYLHARGISHRDIKPANIMFDKNF--HPKRIDFGFCREN--SPKLKTYCGTDLLIAPEIMRHRCYDGEKADMWSFGV
|..|..|.| ..| |||||| ||. |.|     | |||||...     ||.| |||    ||||.  . ||| |.|.|| ||
IVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGV
Kinase 94174.m00173.AA ULK 1-108 26 3.9e-24 81.22 In-house 99-244 (329) Show / Hide 
Range on Protein: 1-108
Range on HMM: 99-244/329
Sequence Identity: 26% (38 aa)

MEFLENGDMQTFINQEYT----------CKPQEYIRIVSEILEALSYLHARGISHRDIKPANIMFDKNF------------HPKRIDFGFCRE-NSP---
||. . || ...|..  .             || | .   ||... .|| ..| ||||||.||. ....            . |  ||||..  ...   
MEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNME

--KLKTYC------GTDLLIAPEIMR-H--RCYDG-EKADMWSFGV
   ..|.       || |  ||.|   .  ..  .  |.|.||.|.
QQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGC
Kinase 94174.m00173.AA ULK 1-108 25 1.5e-23 80.49 In-house 96-240 (324) Show / Hide 
Range on Protein: 1-108
Range on HMM: 96-240/324
Sequence Identity: 25% (37 aa)

MEFLENGDMQTFINQEYT---------CKPQEYIRIVSEILEALSYLHARGISHRDIKPANIMFDKNF------------HPKRIDFGFCRE-NS-----
||. . || ...|..  .            || | .   |.... .|| ..| ||||||.||.  ...            . |  ||||..  ..     
MEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQ

PKLKTYC------GTDLLIAPEIMR-H--RCYDG-EKADMWSFGV
 ...|..      || |  ||.|   .  ..  .  |.|.||.|.
QMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGC
Kinase 94174.m00173.AA TKL 1-135 20 1.6e-23 81.55 In-house 117-314 (364) Show / Hide 
Range on Protein: 1-135
Range on HMM: 117-314/364
Sequence Identity: 20% (41 aa)

MEFLENGD-MQTFINQEYTCKPQEYIRIVSEILEALSYLHA--------RGISHRDIKPANIMFDKNFH--------------PKRIDFGFCRENSP---
||. ..|.   ...       ..  .|.. .|  ...|||.        ..| |||.|..||. |.|..              .|  |||..|..|.   
MEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGN

-------------------KLKTYCGTDLLIAPEIMRHRCYDGEKA---------------DMWSFGVTAHIFVTRNLPFE-YKSDSQY---------WK
                   .. | |||    |||..|   .. ||.               |..|||.     .|| .|.. |......         ..
MNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMM

DVKNR
.....
VCDKG
Kinase 94174.m00173.AA RSK 27-108 36 4.1e-23 81.56 In-house 109-200 (278) Show / Hide 
Range on Protein: 27-108
Range on HMM: 109-200/278
Sequence Identity: 36% (34 aa)

IVSEILEALSYLHARGISHRDIKPANIMFDK---NFHPKRIDFGFCRENSPK----LKTYCGTDLLIAPEIMR---HRC-YDGEKADMWSFGV
. .||  |...|| .|| |||.|| ||..|    . | | .|||||......    ..|.|.|   .|||. .   ... .| . .| ||.||
YMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHD-KACDWWSLGV
Kinase 94174.m00173.AA QIK 26-125 40 8e-23 82.15 In-house 122-223 (272) Show / Hide 
Range on Protein: 26-125
Range on HMM: 122-223/272
Sequence Identity: 40% (41 aa)

RIVSEILEALSYLHARGISHRDIKPANIMFDKNFHPKRIDFGFC--RENSPKLKTYCGTDLLIAPEIMRHRCYDGEKADMWSFGVTAHIFVTRNLPFEYK
|. ..|. |  |.| |.| |||.|  ||..|.|   | .||||    ..   |.|.||.    |||..  . ||| |.| || ||   . |.  |||  |
RWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVDIWSMGVVLYVLVCGALPFDGK

SD
..
TL
Kinase 94174.m00173.AA S_TKc 1-177 18 5.2e-13 13.89 SMART 1-231 (231) Show / Hide 
Range on Protein: 1-177
Range on HMM: 1-231/231
Sequence Identity: 18% (46 aa)

M-----------------------------------------------------------------EFLEN--GDMQTFINQEYT------CKPQEYIRI
                                                                  |....  ||. ..| .  .        . .  ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFY

VSEILEALSYLHARGISHRDIKPANIMFDKNFHPKRIDFGFCRENSPKLKTYCGTDLLIAPEIMRHRCYDGEKADMWSFGVTAHIFVTRNLPFEYKSDSQ
. .|..|| |.| .|| |||.||.||..|.  | | .|||..|.     .|.|||   .|||..    |...|.|.||.|..  .....  ||.   . .
MYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQM

YWKDVKNRTLKIENQAHGIIGWLVDQTVKINPDERMEAGELLE----NLKNKIT
 .| ..          .  .  ....  . .|..|. | |.|.      .    
MFKKIG---------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 94174.m00173.AA TyrKc 1-172 13 0.000155 -149.31 SMART 1-280 (280) Show / Hide 
Range on Protein: 1-172
Range on HMM: 1-280/280
Sequence Identity: 13% (39 aa)

MEF-------------------------------------------L----------------------------------ENGDMQTFI-NQEYTCKPQ
 ..                                           |                                  ..|| . .. . . . ...
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

EYIRIVSEILEALSYLHARGISHRDIKPANIMFDKNFHPKRIDFGFCRENSPK------LKTYC-----GTDLLI-----APEIMRHRCYDGEKADMWSF
. . .   | .  .||| ... |||.   |.. ..|.. |  ||| .|.   .       ..|      |.. ..     ||| ......  .| | |||
DLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-TKSDVWSF

GVTAHIFVTR-NLPFEY-----KSDSQYWKDVKNR-TLKIENQ--------AHGIIGWLVDQTVKINPDERMEAGELLENL
||.     |.   | .      .|...  ..||..  ...           ..  .  .  |  . .|..|    |. | .
GVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF