Gene 83629.m00142 (T.vaginalis)
83629.m00142
Species: T.vaginalis
Alias: 83629.m00142, TvagK0780
External Links:
Annotation:
Group:
CAMK
Family:
CAMK-Tvag1
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| 83629.m00142.AA | Protein | None | 315 | None | Fasta, JSON |
| 83629.m00142.kin_dom | Protein Kinase Domain | None | 123 | None | Fasta, JSON |
Protein domains of 83629.m00142.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 83629.m00142.AA | CAMK | 48-124 | 18 | 1.4e-17 | 52.53 | In-house | 202-336 (425) | Show / Hide |
Range on Protein: 48-124
Range on HMM: 202-336/425
Sequence Identity: 18% (25 aa)
HRDLKPDNIVVDGDM-----------------IPHIIDWDDSTDRFSLS-------------------------ISERHGTIPFAA-PEIFSA-------
||||||.|| .| .. |||. .. .. . ... || ...| ||...
HRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQ
------QRK--CESDIFSFGAIMFNMITERYPFYS
.. ..|. | | |.. | . ..|||.
NATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYG
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| Kinase | 83629.m00142.AA | Ciliate-E2-Unclassified | 1-124 | 22 | 5.3e-17 | 55.52 | In-house | 100-272 (352) | Show / Hide |
Range on Protein: 1-124
Range on HMM: 100-272/352
Sequence Identity: 22% (39 aa)
MDYIPGITITKLIS--------GGCVGNRIKKLCML-----------EIFAAIASQL-TLMKEMEIKHRDLKPDNIVVDGDM---IPHIIDWDDST----
|.|..| . . |. |. ....|. ... .|| | . | | .. | |||.||.||..| .. . |||. |
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ
---------DRFSLSISERH----GTIPFA----APEIFSA-QRK----CESDIFSFGAIMFNMITERYPFYS
... .... ||. . |||.. . ..||.|.| |.. |.. .||||.
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYD
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| Kinase | 83629.m00142.AA | Ciliate-E2 | 48-122 | 22 | 4.2e-15 | 48.29 | In-house | 184-296 (365) | Show / Hide |
Range on Protein: 48-122 Range on HMM: 184-296/365 Sequence Identity: 22% (26 aa) HRDLKPDNIVVDGDMIPHIIDWDDSTDRFSLSISERH---------------------------------GTIPFAAPEIFSAQRK----------CESD |||.||.||.. . |||. |.. .. ..| || .. ||||.. . ..| HRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCD IFSFGAIMFNMITERYPF |.|.| |.. |.. ..|| IWSLGVILYEMLFGKPPF |
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| Kinase | 83629.m00142.AA | Pkinase | 48-125 | 27 | 2.2e-11 | 41.3 | Pfam | 131-215 (293) | Show / Hide |
Range on Protein: 48-125 Range on HMM: 131-215/293 Sequence Identity: 27% (24 aa) HRDLKPDNIVVDGDMIP----HIIDWDDST---DRFSLSISERHGTIPFAAPEI--FSAQRKCESDIFSFGAIMFNMITERYPFYSA ||||||.|| .| .. . .|.|. . . . . ||....|||. .. ..|..|.| |.. |.. | ||... HRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGH |
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| Kinase | 83629.m00142.AA | TKL | 48-232 | 13 | 8.4e-09 | 27.84 | In-house | 163-364 (364) | Show / Hide |
Range on Protein: 48-232
Range on HMM: 163-364/364
Sequence Identity: 13% (34 aa)
HRDLKPDNIVVDGDMI--------------PHIIDWDDSTDRF---SLSISE------------------RHGTIPFAAPEIFSAQRK------------
|||||..|| || .. . | | |.. . . . .. . ||. . |||.. | .
HRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCK
-----CESDIFSFGAIMFNMITERYPFY-SAYRTRAGL-------QSLADKFSELQLPNLAETLDVLAEFEQMDDSEQYNHWPTVVSYVEPILTELIKAG
.|..||| ... ..| . |.| |... . .||. . .|. ..
GFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQN-------------------------------------
ARDDYIYNERFQNDPFNRKISELIGLCCKQEPDGRITPEDLHDRI
. ..... . ...|. |....|. | . ... .|.
---HH-K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
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| Kinase | 83629.m00142.AA | Ciliate-A3 | 25-117 | 33 | 1.2e-08 | 24.84 | In-house | 77-176 (237) | Show / Hide |
Range on Protein: 25-117 Range on HMM: 77-176/237 Sequence Identity: 33% (33 aa) LCMLEIFAAIASQLTLMKEMEIKHRDLKPDNIVV--DGDMIPHIIDWDDSTDRFSLSISERHGTIPFAAPEIFSAQRKCES-----DIFSFGAIMFNMIT | ...| |. . ..||....||||||.||.. ||. | | | . .| . |||| ||..| |..||| |...| | LEVIDIAIQITKGMMILKELNLEHRDLKPENILIHNDGEKIIAKISDYGLTKEVQCDLKSIVRTPNYMAPEILSAKKKGSVYDDKIDVWSFGLILYEMFT |
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| Kinase | 83629.m00142.AA | S_TKc | 3-236 | 12 | 6.8e-08 | -61.19 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 3-236
Range on HMM: 1-231/231
Sequence Identity: 12% (39 aa)
YIPGITI-------------TK---------------------------------------------LISG--GCVGNRIKKLCM-----------LEIF
| . .| .| ...| | . .||| ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPEHARFYM
AAIASQLTLMKEMEIKHRDLKPDNIVVDGDMIPHIIDWDDSTDRFSLSISERHGTIPFAAPEIFSAQRKC-ESDIFSFGAIMFNMITERYPFYSAYRTRA
. |.. | . .. | ||||||.|| .| |.| .. . || . |||.. . . ..|. |.| |.. |.. . ||.
YQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYEMLCGYPPFP-------
GLQSLADKFSELQLPNLAETLDVLAEFEQMDDSEQYNHWPTVVSYVEPILTELIKAGARDDYIYNERFQNDPFNRKISELIGLCCKQEPDGRITPEDLHD
......... . ..| |.. .|. |.| ..
---------------QMQMMFKKIG------------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQ
-----RIDSLA
...
DEWDIKCHPWF
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| Kinase | 83629.m00142.AA | CAMKL | 85-122 | 35 | 7.3e-08 | 21.02 | In-house | 195-236 (297) | Show / Hide |
Range on Protein: 85-122 Range on HMM: 195-236/297 Sequence Identity: 35% (15 aa) GTIPFAAPEIFSA--QRKC--ESDIFSFGAIMFNMITERYPF |. |..|||||. .. . . || | | |...|.. ..|| GSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPF |
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| Kinase | 83629.m00142.AA | RIPK | 48-122 | 27 | 1.9e-07 | 21.43 | In-house | 132-228 (290) | Show / Hide |
Range on Protein: 48-122 Range on HMM: 132-228/290 Sequence Identity: 27% (27 aa) HRDLKPDNIVVDGDMIPHIIDWDDSTDR-FSLSISERH--------------GTIPFAAPEIFS---AQR----KCESDIFSFGAIMFNMITERYPF |||||| || ||... | | .|.. | | ..|. ||. . .|| | . . ..|. ||. .|. | . |. HRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNKKPIKVVTPKYDVYSFAIVMWEVLTQKHPY |
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| Kinase | 83629.m00142.AA | Ciliate-E3 | 86-116 | 37 | 2.3e-07 | 19.35 | In-house | 171-202 (202) | Show / Hide |
Range on Protein: 86-116 Range on HMM: 171-202/202 Sequence Identity: 37% (12 aa) TIPFAAPEIFS-AQRKCESDIFSFGAIMFNMI |. .||||. .| . |||. | ||.. .. TPFYAAPEQNDQQQISKESDYYSVGAVFCQLC |
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| Kinase | 83629.m00142.AA | AGC | 85-124 | 34 | 3e-06 | 10.75 | In-house | 267-307 (395) | Show / Hide |
Range on Protein: 85-124 Range on HMM: 267-307/395 Sequence Identity: 34% (15 aa) G--TIPFAAPEIFSAQRKCESDIFS--FGAIMFNMITERYPFYS | | . ||||. . |. | .|..|. |.| . |||. GPCTPEYMAPEIL---YGKACDWWSFGLGCLMYEMLTGYPPFYG |
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| Kinase | 83629.m00142.AA | Ciliate-E9 | 40-59 | 45 | 5.6e-05 | 11.43 | In-house | 127-146 (298) | Show / Hide |
Range on Protein: 40-59 Range on HMM: 127-146/298 Sequence Identity: 45% (9 aa) LMKEMEIKHRDLKPDNIVVD . .. | ||||||.|...| MHQYQNICHRDLKPENMLID |
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| Kinase | 83629.m00142.AA | CAMKL | 48-68 | 47 | 0.000253 | 9.54 | In-house | 150-172 (297) | Show / Hide |
Range on Protein: 48-68 Range on HMM: 150-172/297 Sequence Identity: 47% (11 aa) HRDLKPDNIVVDGDM--IPHIID |||.||.|| .| .. ||| HRDIKPENILLDENGNNNIKIID |
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| Kinase | 83629.m00142.AA | AGC | 48-68 | 50 | 0.000263 | 5.46 | In-house | 177-198 (395) | Show / Hide |
Range on Protein: 48-68 Range on HMM: 177-198/395 Sequence Identity: 50% (11 aa) HRD-LKPDNIVVDGDMIPHIID ||| |||.||. | | .. | HRDYLKPENILLDEDGHIKLTD |
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| Kinase | 83629.m00142.AA | Ciliate-E9 | 104-124 | 52 | 0.000493 | 8.35 | In-house | 207-227 (298) | Show / Hide |
Range on Protein: 104-124 Range on HMM: 207-227/298 Sequence Identity: 52% (11 aa) DIFSFGAIMFNMITERYPFYS |||| | | | |.. ||| . DIFSAGCILFMMVMNQYPFFH |
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| Kinase | 83629.m00142.AA | Ciliate-E3 | 48-59 | 75 | 0.022811 | 3.54 | In-house | 126-137 (202) | Show / Hide |
Range on Protein: 48-59 Range on HMM: 126-137/202 Sequence Identity: 75% (9 aa) HRDLKPDNIVVD | |.||||| || HSDIKPDNILVD |
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