Gene TVAG_216840 (T.vaginalis)
TVAG_216840
Species: T.vaginalis
Alias: TvagK1058, TVAG_216840
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| TVAG_216840.AA | Protein | None | 278 | None | Fasta, JSON |
| TVAG_216840.kin_dom | Protein Kinase Domain | None | 199 | None | Fasta, JSON |
Protein domains of TVAG_216840.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | TVAG_216840.AA | Ciliate-E2-Unclassified | 17-191 | 16 | 2.5e-15 | 49.67 | In-house | 89-340 (352) | Show / Hide |
Range on Protein: 17-191
Range on HMM: 89-340/352
Sequence Identity: 16% (41 aa)
EFSNNELLYLITEDYTALNLKEYVATN-----------------GRLSDTEVL-----RISKSIADALTIMHMQH-VAHGGLDSRAICFDFSM---IPKL
.| . . .|...| ..|..| . .... ... .. . | ..| .| .. . | . | || .. .|.
CFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKI
SYFDFA----------------CDINIRKIEKVEVNIMNYF----PPEFLQF-NSNNQ--FTKDAWCLGIITYFMICAQYPFISANQIK-----------
. | .. .|..... . . || .|| || | ... . | |.||.| |.|. .||| . |...
IDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINN
-----LVNIIIKCQYMLPPTTH----PTIH--------ALIAKTLVQDPSQR
| ..|..... |. . ... |. | |. .|..|
AYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKR
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| Kinase | TVAG_216840.AA | SNRK | 114-203 | 33 | 1e-13 | 41.0 | In-house | 165-254 (254) | Show / Hide |
Range on Protein: 114-203 Range on HMM: 165-254/254 Sequence Identity: 33% (30 aa) YFPPEFLQFNSNNQFTKDAWCLGIITYFMICAQYPFISANQIKLVNIIIKCQYMLPPTTHPTIHALIAKTLVQDPSQRANARYISMMLRS | || | | | | ||.| | ..| | || || . |. |.| .|. . ||.. ||.|| .|| | YSAPEILLGDSYDAPAVDIWSLGVILYMLVCGQAPFQEANDSETLTMIMDCKYTVPDHVSDECRDLIQSMLVRDPKKRASLEEIVSHSWV |
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| Kinase | TVAG_216840.AA | CAMKL | 131-197 | 28 | 5.5e-13 | 37.62 | In-house | 218-291 (297) | Show / Hide |
Range on Protein: 131-197 Range on HMM: 218-291/297 Sequence Identity: 28% (22 aa) DAWCLGIITYFMICAQYPFISA--------NQIKLVNIIIKCQYMLPPTTHP-TIHALIAKTLVQDPSQRANARYI | | .|.| |.|.| ..|| . |. .| ..|... |. |. |. . || | |. .|..|... | DIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQI |
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| Kinase | TVAG_216840.AA | MARK | 131-194 | 28 | 9.2e-11 | 31.59 | In-house | 188-253 (262) | Show / Hide |
Range on Protein: 131-194 Range on HMM: 188-253/262 Sequence Identity: 28% (19 aa) DAWCLGIITYFMICAQYPFISAN--QIKLVNIIIKCQYMLPPTTHPTIHALIAKTLVQDPSQRANA | | ||.. |||.| ..|| .. . .| | ...| |. . .. || . |. .|..|. . DIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTI |
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| Kinase | TVAG_216840.AA | CAMK | 131-194 | 22 | 2.1e-10 | 28.98 | In-house | 316-416 (425) | Show / Hide |
Range on Protein: 131-194 Range on HMM: 316-416/425 Sequence Identity: 22% (23 aa) DAWCLGIITYFMICAQYPFISA-------------NQIKLVNIIIKCQYMLPPTT--HPT----------------------IHALIAKTLVQDPSQRAN | | .|.|.|.| | .|| . |. .| |.|..| || ... || | |. ||..|.. DMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMT A . I |
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| Kinase | TVAG_216840.AA | AMPK | 131-193 | 33 | 1.2e-09 | 24.86 | In-house | 182-244 (254) | Show / Hide |
Range on Protein: 131-193 Range on HMM: 182-244/254 Sequence Identity: 33% (21 aa) DAWCLGIITYFMICAQYPFISANQIKLVNIIIKCQYMLPPTTHPTIHALIAKTLVQDPSQRAN | | |.| | |.|. || |. .| |....| .| | .. || . | || .|.. DIWSCGVILYAMLCGYLPFDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRIT |
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| Kinase | TVAG_216840.AA | S_TKc | 3-201 | 18 | 6.6e-08 | -60.98 | SMART | 18-231 (231) | Show / Hide |
Range on Protein: 3-201
Range on HMM: 18-231/231
Sequence Identity: 18% (45 aa)
AVSKL-----------------------KHLNIAATIEFSNNELLYLITEDYTA--LNLKEYVATNGR------LSDTEVLRISKSIADALTIMHMQHVA
.. | .| || ... .. ||...| .|..| .|| .. .. .. . |..|| .| ...
CRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGII
HGGLDSRAICFDFSMIPKLSYFDFACDINIRKIEKVEVNIMNYFPPEFLQFNSNNQFTK---DAWCLGIITYFMICAQYPFISANQIKLVNIIIKCQYML
| | | .| |.. | .|. . . . .| .|| | ...| | | .|.| | |.| . || .. .. ..|
HRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL------GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG------
PPTTHPTIHALIAKTLVQDPSQRANARYISM---------ML
| .| | |. ||..| | . .
----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
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| Kinase | TVAG_216840.AA | PLK1 | 113-203 | 27 | 1.1e-07 | 21.11 | In-house | 164-253 (253) | Show / Hide |
Range on Protein: 113-203 Range on HMM: 164-253/253 Sequence Identity: 27% (25 aa) NYFPPEFLQFNSNNQFTKDAWCLGIITYFMICAQYPFISANQIKLVNIIIKCQYMLPPTTHPTIHALIAKTLVQDPSQRANARYISMMLRS || || |. . | | | .| | | .. | || . | |..|..| ... . || | | .||..| ... . . NYIAPEVLN-KKGHSFEVDIWSIGCIMYILLFGQPPFETKCLKETYSRIKKNEYRIPSHISQPAAQLIRKMLDPDPTRRPTIEQVLNDEFF |
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| Kinase | TVAG_216840.AA | MELK | 1-191 | 24 | 1.3e-07 | 21.74 | In-house | 48-242 (254) | Show / Hide |
Range on Protein: 1-191 Range on HMM: 48-242/254 Sequence Identity: 24% (47 aa) MDAVSKLKHLNIAATIEF-SNNELLYLITEDYTALNLKEYVATNGRLSDTEVLRISKSIADALTIMHMQHVAHGGLDSRAICFDFSMIPKLSYFDFACDI |||. .|.| .| . .. .... | . .. .|. . ||.. | . . | |. .| | || | . || . || | . MDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEETRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKT NIRKIEK---VEVNIMNYFPPEFLQFNSNNQFTKDAWCLGIITYFMICAQYPFISANQIKLVNIIIKCQYMLPPTTHPTIHALIAKTLVQDPSQR || . . | || .| . | | .||. | ..| || | . |.. | |. | |. . | || .| KGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFLPFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKR |
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| Kinase | TVAG_216840.AA | AGC | 133-191 | 20 | 2e-07 | 13.71 | In-house | 287-373 (395) | Show / Hide |
Range on Protein: 133-191 Range on HMM: 287-373/395 Sequence Identity: 20% (18 aa) WC--LGIITYFMICAQYPFISAN----------QIKLVNIII------KCQYMLP----------PTTHPTIHALIAKTLVQDPSQR |. ||.. | |.. . || . | . .. . |. ... .| . | || | |. ||..| WSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKR |
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| Kinase | TVAG_216840.AA | Pkinase | 131-201 | 18 | 2e-06 | 23.65 | Pfam | 194-293 (293) | Show / Hide |
Range on Protein: 131-201 Range on HMM: 194-293/293 Sequence Identity: 18% (18 aa) DAWCLGIITYFMICAQYPFISA------NQIKLVNIIIKCQYMLPPTTH---------------------PTIHALIAKTLVQDPSQRANARYISMM--L | | .|.| | |.| . || .. .|..... | ..... . . .. .| . | .||..| .|. | . DMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | TVAG_216840.AA | Ciliate-E2 | 131-191 | 27 | 2e-06 | 18.37 | In-house | 278-352 (365) | Show / Hide |
Range on Protein: 131-191 Range on HMM: 278-352/365 Sequence Identity: 27% (22 aa) DAWCLGIITYFMICAQYPFISANQIKLVNIIIKCQ-YMLPPTTHPT-----IH--------ALIAK----TLVQDPSQR | |.||.| |.|.. ..|| .||| .| . |. . .. |. . .. || | |. ||..| DIWSLGVILYEMLFGKPPF--QQQIKQCKIDFPCPEWQKD-TQ-CIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKR |
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| Kinase | TVAG_216840.AA | Ciliate-E2 | 18-75 | 17 | 0.262802 | 0.22 | In-house | 101-187 (365) | Show / Hide |
Range on Protein: 18-75 Range on HMM: 101-187/365 Sequence Identity: 17% (15 aa) FS--NNELLYLITEDYTALNLKEYVATN-----------GRLSDTEVLRISKSIAD---------------ALTIMHMQH-VAHGGL | ... .||..| . .|..| | ..... |...|.| |.. || .| .. . | . FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDI |
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| Kinase | TVAG_216840.AA | Pkinase | 6-72 | 19 | 3.250318 | 1.84 | Pfam | 56-131 (293) | Show / Hide |
Range on Protein: 6-72 Range on HMM: 56-131/293 Sequence Identity: 19% (15 aa) KLKHLNIAATIEFS-NNELLYLITEDYTAL----NLKEYVA--TNGRL--SDTEVLRISKSIADALTIMHMQHVAH .|.| || .... .. .|...| |..|. .|.. |. |. .. . |. .| .| . . | RLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIH |
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