Gene 87640.m00151 (T.vaginalis)

87640.m00151

Species: T.vaginalis
Alias: TvagK0196, 87640.m00151
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
87640.m00151.AA Protein None 205 None Fasta, JSON
87640.m00151.kin_dom Protein Kinase Domain None 192 None Fasta, JSON

Protein domain

Protein domains of 87640.m00151.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase 87640.m00151.AA Pkinase 14-205 24 1.4e-40 144.54 Pfam 1-214 (293) Show / Hide 
Range on Protein: 14-205
Range on HMM: 1-214/293
Sequence Identity: 24% (53 aa)

LQLKEVIGNGQSGVVYLVNDPKYRRDFALKSVPLTMFHPSG---------AECMMNIDDPNVIRLYKFEPFESAAYLLEEYCPN-----SLDSALK--KR
......|| | .|.||.  . .... .|.| ...   ...          .. | ... ||..||| .   ..  |.  |||..     .| . ..  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GSF--ENDLLLHYADGILKGIRALHQLRIAHLDIKPANFLIDTFSRV----RVCDFGISNK--FESNELCTKFGGSVPFMSPEILQLQPFDPFKADIWAI
|.|  . . . .|.  ||.|.  .|. .| | |.||.|.|||    .    ..||||.. .    .|. .| | |. ..|.||... .. .. |.|.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVTFFIIATGVLPWEG
|..... ..| .|. |
GCILYEMLCGRPPFPG
Kinase 87640.m00151.AA CAMK 19-205 16 7.9e-38 118.97 In-house 1-336 (425) Show / Hide 
Range on Protein: 19-205
Range on HMM: 1-336/425
Sequence Identity: 16% (57 aa)

VIGNGQSGVVYLVNDPKYR------------RDFALKSVP---------------------------------LTMFHPSGAECMMN-------IDDPNV
..| |. |.|.|. . .              . .| | ..                                    . ..  |.|..       .| ||.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IRLYK-FE----------------PFES---AAYLLE---EYCPN-----SLDSALKKRGS---------------FENDLLLHYADGILKGIRALHQLR
|.||  .|                 | .     |.     |||..      | . ....|.               |. .   .|   |. ... .|.. 
IKLYEVYEDPHYFKNTNDYETSKQVF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IAHLDIKPANFLIDTFS-----------------RVRVCDFGISNKFES------------------------NELCTKFGGSVPFMS-PEILQL-----
|.|.|.|| | |.|. .                  . ..||| .|||..                        ..... | |. ..|. ||.|.      
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------QPFDPFKADIWAIGVTFFIIATGVLPWEG
        .| ...|.|.|..||  .|  .| .|..|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYG
Kinase 87640.m00151.AA CAMKL 14-205 24 2.9e-33 103.39 In-house 1-238 (297) Show / Hide 
Range on Protein: 14-205
Range on HMM: 1-238/297
Sequence Identity: 24% (59 aa)

LQLKEVIGNGQSGVVYLVNDPKY-RRDFALKSVP--------LTMFHPSG------------AECMMNID---DPNVIRLYKFEPFESA------AYLLE
 .. ...| |  |.| |  . .. ..  | | .          .. .. |            ...|. ..    ||.|.||     ..        ||  
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCPNS---LDSALKKR----GSFENDLLLHYADGILKGIRALHQLRIAHLDIKPANFLID-TFS-RVRVCDFGISNKFES-----NELCTKFGGSVPFM
|||..    |   ..|.    |... .   .|   |. ..  .|...|.| |||| | |.|   .  . ..||| ||...      ..... | || |.|
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

SPEILQL--QPFDPFKADIWAIGVTFFIIATGVLPWEG
.|||.|   .|.| .|.|||..||. . . .| ||...
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDD
Kinase 87640.m00151.AA Ciliate-E2 14-203 17 3.1e-31 104.46 In-house 1-296 (365) Show / Hide 
Range on Protein: 14-203
Range on HMM: 1-296/365
Sequence Identity: 17% (52 aa)

LQLKEVIGNGQSGVVYLVNDPKYRRDF------------------ALKSVPLTMFHPSGAECMMNIDDPN-----------------------VIRLYKF
  . ..||.|. |.||.... | ...|                  . | . . ...... | ...... .                       .|..| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

EP--FESAAYLLEEYCPN-SLDSALKKR-----------GSFENDLLLHYADGILK---------------GIRALHQLR-IAHLDIKPANFLIDTFSRV
     ..  ||  |||   .| . .|..           ..|     ...   ||.               ... ||.   | | |||| | |.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

RVCDFGISNKFESN----------ELCTKFG-----------------------GSVPFMSPEILQLQPFDP--------FKADIWAIGVTFFIIATGVL
 ..|||.| |.  .          ....  .                       |. ..|.||||. .. |         .|.|||..||....  .| .
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PW
|.
PF
Kinase 87640.m00151.AA Ciliate-E2-Unclassified 16-202 21 3.3e-29 98.46 In-house 3-269 (352) Show / Hide 
Range on Protein: 16-202
Range on HMM: 3-269/352
Sequence Identity: 21% (58 aa)

LKEVIGNGQSGVVYLV---NDPKY--------RRDFALKSV------------PLTMFHPSGAE--------CMMNIDDPNVIRLYKFEPFESAAYLLEE
. ..||.|. |.||..   .. .|         .... |..               . . .  .         . |...|......  .  .   |.  |
IIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVME

YCPN-SLDSALKKRGS-----------------FENDLLL-----HYADGILKGIRALHQL-RIAHLDIKPANFLIDTFS---RVRVCDFGISNKFESN-
||.. .|   .|||..                 |.    .     .|.  ||.|.  ||.   | | |||| | |.|      .....||||| | ..| 
YCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNN

---------------ELCTKFGGSVPFM----SPEILQLQPFDP---FKADIWAIGVTFFIIATGVLP
               .... | |.  .|    .||.|| |  |    .|.|||. || .. . .| .|
NCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYP
Kinase 87640.m00151.AA ULK 14-203 21 7e-27 92.45 In-house 1-255 (324) Show / Hide 
Range on Protein: 14-203
Range on HMM: 1-255/324
Sequence Identity: 21% (55 aa)

LQLKEVIGNGQSG-VVYLV--NDPKY-RRDFALKSVPLTMFHPSGAE-------CMMN--------ID---DPN--VIRLYKFEPFE--SAAYLLEEYCP
 .|....| |. | .||    .. .    ..| | ...  .  .  |       .. .        ..    ||  ...||..         |.  |||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

N-SLDSALKKRGS---------FENDLLLHYADGILKGIRALHQLRIAHLDIKPANFLIDTFS------------RVRVCDFGISNKFESN----ELCTK
   |.. .||..          .. .  ...   |. | ..||.  | | ||||.| ||                .. ..||| . ....|     .|. 
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

FG------GSVPFMSPEILQLQ----PFDPFKADIWAIGVTFFIIATGVLP---W
.       |.  .|.|.||| |    |.. .|.||| .|. |. . .|  |   |
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW
Kinase 87640.m00151.AA S_TKc 14-205 22 7.6e-25 89.78 SMART 1-220 (231) Show / Hide 
Range on Protein: 14-205
Range on HMM: 1-220/231
Sequence Identity: 22% (52 aa)

LQLKEVIGNGQSGVVYLVNDPKYRRDFALKSVPLTMFHPSGAECMMNIDDPNVIRLYKFEPFESAAYLLEEYCPN---SLDSALKKRGS------FENDL
 .. ..|| |  |.||.. . |  | .|.| ..      .  ..... . ||...|| .    .  |.  |||..   .| . .||||.      |    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H

LLHYADGILKGIRALHQLRIAHLDIKPANFLIDTFSRVRVCDFGISNKFESNELCTKFGGSVPFMSPEILQLQPFDPFKADIWAIGVTFFIIATGVLPWE
  .|.  |....  .|...| | |.||.| |.|.  .. .||||.. ..      | | |.  .|.||.|   .....|.|.|..|..... ..|  |..
ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP

-----------------------------------G
                                    
QMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTAEALQ
Kinase 87640.m00151.AA STE 14-203 21 2.5e-24 82.87 In-house 1-268 (359) Show / Hide 
Range on Protein: 14-203
Range on HMM: 1-268/359
Sequence Identity: 21% (60 aa)

LQLKEVIGNGQSGVVYLV---------NDPKY------RRDFALKSVPLTMFHP----------------------SGAECMMNID--DPNVIRLYKFEP
... |.||.| .|.||.             .        . .| | ..|    .                         . |.. .   ||... |  . 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

FE-------SAAYLLEEYCP-NSLDSALK---KRGS-----------FENDLLLHYADGILKG-IRALHQLRIAHLDIKPANFLIDTFSRVRVCDFGISN
 |       .  ..  ||..  |||. .|   ..|            |. ... ...  ||||    ||...| | |||||| |.     |  ||||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

KFESN-----------------ELCTKFGGSVPFMSPEILQLQPFDPF------KADIWAIGVTFFIIATGVLPW
.....                 . .. | |.  .|.||..| .  .        |.||| .| |    |||  ||
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-RDKGYDTKCDIWSLGCTIIEMATGKPPW
Kinase 87640.m00151.AA LKB 119-205 39 3.4e-24 68.77 In-house 120-211 (265) Show / Hide 
Range on Protein: 119-205
Range on HMM: 120-211/265
Sequence Identity: 39% (36 aa)

LHQLRIAHLDIKPANFLIDTFSRVRVCDFGI---SNKFESNELCTKFGGSVPFMSPEILQL--QPFDPFKADIWAIGVTFFIIATGVLPWEG
||  |. | |||| | |. .   . .||||.   ...|.  . ||.  ||  |  ||. .     |..||.|||. ||| . ..||  | ||
LHSQRVVHKDIKPGNLLLTHDNTLKICDFGVAEQLHHFQRDDCCTTSQGSPAFQPPECANGNHDTFSGFKVDIWSMGVTLYNMTTGKYPFEG
Kinase 87640.m00151.AA ULK 64-203 25 6.1e-24 80.51 In-house 78-259 (329) Show / Hide 
Range on Protein: 64-203
Range on HMM: 78-259/329
Sequence Identity: 25% (46 aa)

PNVIRLYKFEPFE--SAAYLLEEYCPN-SLDSALKKRGS----------FENDLLLHYADGILKGIRALHQLRIAHLDIKPANFLIDTFS----------
||...||..         |.  |||.   |.. .||..           .. .  ...   || | ..||. .| | ||||.| ||.             
PNIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHP

--RVRVCDFGISNKFESN-----ELCTKFG-----GSVPFMSPEILQLQ----PFDPFKADIWAIGVTFFIIATGVLP---W
  .. ..||| . .....      ..|  .     |.  .|.|.||| |    |.. .|.||| .|. |. . .|  |   |
NGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW
Kinase 87640.m00151.AA MARK 119-205 37 1.9e-22 70.3 In-house 120-208 (262) Show / Hide 
Range on Protein: 119-205
Range on HMM: 120-208/262
Sequence Identity: 37% (33 aa)

LHQLRIAHLDIKPANFLIDTFS--RVRVCDFGISNKFESNELCTKFGGSVPFMSPEILQLQPFDPFKADIWAIGVTFFIIATGVLPWEG
.|. .|.| |||| | |||      .  .||| |........ . | |. |.|.|||.. .| | .|.|||. ||  ... .| .|..|
CHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDG
Kinase 87640.m00151.AA STE11 84-190 31 3.4e-19 66.24 In-house 93-225 (303) Show / Hide 
Range on Protein: 84-190
Range on HMM: 93-225/303
Sequence Identity: 31% (42 aa)

EYCPN-SLDSALK-KRGS--FENDLLLHYADGILKGIRALHQLRIAHLDIKPANFLIDTFSR-VRVCDFGISNKFESNELCTKF-----------GGSVP
||||. || | |. |.|   |.  .  .|   ||.|.  ||. .| | |||.|| |.|. .  ..  |||.. ..... .||.             |.. 
EYCPGGSLSSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPY

--------FMSPEILQLQPFD--PFKADIWAIG
        .|.||..  .. |    |||||..|
NSMMGTPMWMAPEVIKQEGRDGYGRKADIWSLG
Kinase 87640.m00151.AA TyrKc 14-200 17 2.4e-07 -103.8 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-200
Range on HMM: 1-280/280
Sequence Identity: 17% (49 aa)

LQLKEVIGNGQSGVVYL-VNDPKYRRDFALKSVP---LTMFHPSGAECMMNI--DDPNVIRLYKFEPFE-------SAAYLLEEYCPN-SLDSALKKRGS
..|....|.|. |.||. . .    .. | |..    . .|. . |. |...  . ||..|||     .          ... ||.|. .|.. |.|.. 
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDAREDFM-REARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

-FENDLLLHYADGILKGIRALHQLRIAHLDIKPANFLIDTFSRVRVCDFGISNKFESN--------ELCTKF--GGS--VPF--MSPEILQLQ-------
 . .. ||...  | .| . ||. .. | |.   | |..   .|...||| | . ..            .|   ||   .|   |.|| ..         
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSD

------------------PFD-----------------------PFK-----------------ADIWAI----GVTFFIIATGV
                  . .                       |                    . |.       ||  |    
VWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 87640.m00151.AA ULK 14-29 37 0.002995 7.3 In-house 1-16 (329) Show / Hide 
Range on Protein: 14-29
Range on HMM: 1-16/329
Sequence Identity: 37% (6 aa)

LQLKEVIGNGQSGVVY
 .|....| |. |.||
YCLNHCLGKGSFGKVY
Kinase 87640.m00151.AA MARK 15-71 24 0.006747 5.5 In-house 2-66 (262) Show / Hide 
Range on Protein: 15-71
Range on HMM: 2-66/262
Sequence Identity: 24% (16 aa)

QLKEVIGNGQSGVVYLVNDPKYRRDFALKSVP---LTM-----FHPSGAECMMNIDDPNVIRLYK
 .. .|| |  ..|.|. . ...| .|.| ..   |.         . .| |. .| ||.|.|..
KMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFH
Kinase 87640.m00151.AA STE11 14-30 47 0.074526 2.84 In-house 1-17 (303) Show / Hide 
Range on Protein: 14-30
Range on HMM: 1-17/303
Sequence Identity: 47% (8 aa)

LQLKEVIGNGQSGVVYL
 |..|.|| |. |.||.
WQKGEIIGKGAFGTVYK