82699.m00115

Species: T.vaginalis
Alias: 82699.m00115, TvagK0159
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
82699.m00115.AA Protein None 312 None Fasta, JSON
82699.m00115.kin_dom Protein Kinase Domain None 243 None Fasta, JSON

Protein domain

Protein domains of 82699.m00115.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 82699.m00115.AA Ciliate-E2 167-256 25 5.6e-21 68.73 In-house 253-365 (365) Show / Hide
Range on Protein: 167-256
Range on HMM: 253-365/365
Sequence Identity: 25% (31 aa)

YMAPEFFNG--------HPIDPIKADIWSLGVTFYFMAAHCYPFFSKDAHTYQKLVLKGNYALQ-----------------SVQCSLL-RSIISK----C
||||| .||        .     |.|||||||..|.|    .||        |.  ..... ..                   ..|.    .|.|    .
YMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRM

LDLNPEKRPS-IEEMLSLDYF
|. .||||.. .|. |   .|
LQKDPEKRITGWEQILNHPWF

Kinase 82699.m00115.AA Ciliate-E2-Unclassified 167-256 24 3.8e-18 59.54 In-house 228-352 (352) Show / Hide
Range on Protein: 167-256
Range on HMM: 228-352/352
Sequence Identity: 24% (31 aa)

YM----APEFFNGHPIDP---IKADIWSLGVTFYFMAAHCYPFFSKDAHT----------------YQKLVLKGNYALQS-------VQCS-----LLRS
||    ||| . |.  |    .|.||||||| .|.|    |||....                   ...  ...|.  ..        . |     ... 
YMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFIND

IISKCLDLNPEKRPSIEEMLSLDYF
...|.|. ||.||...|. |   .|
LLQKMLKKNPNKRITFEQILNHPWF

Kinase 82699.m00115.AA CAMK 167-256 21 1.1e-17 52.85 In-house 285-425 (425) Show / Hide
Range on Protein: 167-256
Range on HMM: 285-425/425
Sequence Identity: 21% (31 aa)

YMA-PEFFNG-------------HPIDPIKADIWSLGVTFYFMAAHCYPFFSK-------------DAHTYQKLVLKGNYA-LQSVQCS-----------
||| || .||             .| .. |.|.||.||  |.|   ..|| ..             . .   . ..||.|    .               
YMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWD

------------LLRSIISKCLDLNPEKRPSIEEMLSLDYF
              .. |.|.|  .||||..||. |.   .
DISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM

Kinase 82699.m00115.AA ULK 166-256 29 1.9e-17 58.48 In-house 212-324 (324) Show / Hide
Range on Protein: 166-256
Range on HMM: 212-324/324
Sequence Identity: 29% (34 aa)

LYMAPEFFNGH----PIDPIKADIWSLGVTFYFMAAHCYPFFSKDAHTYQ----KLVLKG--------NYALQSV------QC-SLLRSIISKCLDLNPE
|||||. ..|.    | . .|.||||||. || |    |||||  . ...    ||. .|        |  .|        .. . ....|...|  ...
LYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEK

KRPSIEEMLSLDYF
.| |.||...   |
DRISWEEIFNHPWF

Kinase 82699.m00115.AA ULK 166-256 27 3e-17 56.85 In-house 216-329 (329) Show / Hide
Range on Protein: 166-256
Range on HMM: 216-329/329
Sequence Identity: 27% (32 aa)

LYMAPEFFNGH----PIDPIKADIWSLGVTFYFMAAHCYPFFSKDAHTYQ-----KLVLKG--------NYALQ------SVQCSL-LRSIISKCLDLNP
|||||. ..|.    | .  |.||||||. || |    .||..  . ...     ||. ..        .  ||      ..|.|  ....|...|  ..
LYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDE

EKRPSIEEMLSLDYF
..| |.||...   |
KDRISWEELFNHPWF

Kinase 82699.m00115.AA Pkinase 167-256 22 5.4e-17 61.17 Pfam 177-293 (293) Show / Hide
Range on Protein: 167-256
Range on HMM: 177-293/293
Sequence Identity: 22% (26 aa)

YMAPEFFNGHPIDPIKADIWSLGVTFYFMAAHCYPFFSK------DAHTYQKLVLKGNYALQSVQC---------------------SLLRSIISKCLDL
|||||  .|.. .. |.|.||.|...| |.    || ..      |     ...... .  .. .                      . ....|..||..
YMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCK

NPEKRPSIEEMLSLDYF
.|.|||..|. |  ..|
DPKKRPTAEQILQHPWF

Kinase 82699.m00115.AA MARK 165-256 39 2.2e-16 50.26 In-house 169-262 (262) Show / Hide
Range on Protein: 165-256
Range on HMM: 169-262/262
Sequence Identity: 39% (37 aa)

LLYMAPEFFNGHPIDPIKADIWSLGVTFYFMAAHCYPFF--SKDAHTYQKLVLKGNYALQSVQCSLLRSIISKCLDLNPEKRPSIEEMLSLDYF
. ||||| |.. | |  |.|||||||  |||   ..||   ..|  . .| .|.|.|   .     .|..|.. | .|||.||.||| ..   .
PPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

S_TKc 82699.m00115.AA S_TKc 14-256 21 1.2e-15 52.58 SMART 1-231 (231) Show / Hide
Range on Protein: 14-256
Range on HMM: 1-231/231
Sequence Identity: 21% (58 aa)

LKISSVIAEGSFGSLILVYSVTEQKNYALKRIQENYFLNPIDYMKRIDQISFVKPYTYYRLDGYVYMLQDYSPS---DLYNCLKLHHN------LTEEQL
 .|  .| .|.||.  ... .  .. .|.|.|  . ... |. .|. .    || | ...  ...||  .| .    ||.  .| .        ..| . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HA

LKLCYEVLISVKE------YHRNPPENGQIKPSAFILDRYGRITVSQLCSIEEFKSAQSMPRNYEC--LLYMAPEFFNGHPIDPIKADIWSLGVTFYFMA
 ...|...  ..        ||       .||.   ||.           |  | .|  .  .  |  . ||||| .   . .. |.|.||.|...| |.
RFYMYQICCALEYCHSHGIIHRD------LKPENILLDE--------HIKICDFGLARQL--TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

AHCYPFFSKDAHTYQKLVLKGNYALQSVQCSLLRSIISKCLDLNPEKRPSIEEMLS-------LDYF
. . ||   .. ...|..            . ....|.|||. .|||||.. | |          .|
CGYPPFP-QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 82699.m00115.AA CAMKL 165-256 33 1.1e-14 43.12 In-house 197-297 (297) Show / Hide
Range on Protein: 165-256
Range on HMM: 197-297/297
Sequence Identity: 33% (34 aa)

LLYMAPEFFNG--HPIDPIKADIWSLGVTFYFMAAHCYPFFSK--------DAHTYQKLVLKGNYAL-QSVQCSLLRSIISKCLDLNPEKRPSIEEMLSL
. ||||| |.|   | |  |.||||.||. |.|    .||           .  .. . . .| |     .. | .|..|.| |  ||||||.|.. .. 
PPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNH

DYF
  .
PWM

Kinase 82699.m00115.AA CAMKK-Unclassified 182-256 37 9.6e-14 40.84 In-house 313-392 (392) Show / Hide
Range on Protein: 182-256
Range on HMM: 313-392/392
Sequence Identity: 37% (30 aa)

KADIWSLGVTFYFMAAHCYPFFSKDAHTYQK-LVLKGNYALQS---VQCS-LLRSIISKCLDLNPEKRPSIEEMLSLDYF
|||||||||||| |. |  ||..|.     . . .... .. .     || .. . | |..| ||.|| .|. ||  ..|
KADIWSLGVTFYCMVYHSLPFWHKNLQELFHQMICQKEINFPPQYHPHCSHEFKDLIQKMCDKNPKKRITIDQMLVHPWF

Kinase 82699.m00115.AA STE 164-256 19 3.2e-13 43.15 In-house 226-359 (359) Show / Hide
Range on Protein: 164-256
Range on HMM: 226-359/359
Sequence Identity: 19% (26 aa)

CLLYMAPEFFNG------HPIDPIKADIWSLGVTFYFMAAHCYPFFSKDAHTYQKLVLKGNYALQ-----------------------------------
.  .||||  ..      .. | .|.|||||| |   ||  ..|..    .    . ...... |                                   
TP-WMAPEVIQQNGQGRDKGYD-TKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYP

SVQCSLLRSIISKCLDLNPEKRPSIEEMLS--LDYF
.   . ..  |.|||. .|.|||. ...|.     .
HKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI

Kinase 82699.m00115.AA NEK 167-256 31 3.9e-12 39.41 In-house 190-286 (286) Show / Hide
Range on Protein: 167-256
Range on HMM: 190-286/286
Sequence Identity: 31% (31 aa)

YMAPEFFNGHPIDPIKADIWSLGVTFYFMAAH--CYPFFSK--DAHTYQKLVLKG-NYA-LQSVQ-CSL-LRSIISKCLDLNPEKRPSIEEMLSLDYF
||.|| ... | .  |.||||||.  | |..     || ..  . .   . . || .|. ..| .  |  |...||..|  .||.|||... |.. . 
YMSPEVCQNKPYNN-KSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI

Kinase 82699.m00115.AA TyrKc 14-256 16 1.6e-05 -133.22 SMART 1-280 (280) Show / Hide
Range on Protein: 14-256
Range on HMM: 1-280/280
Sequence Identity: 16% (50 aa)

LKISSVIAEGSFGSLIL-VYSVTEQKNYALKRIQENY---FLNPIDYMKRI--DQISFVKPYTYYRLD-------GYVYMLQDYSPS-DLYNCLKLHHN-
..   .. || ||   . ...     . | | ..|.    |.. .  |...  .    |. | . . .       . ....  | |  || . |. |.. 
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

LTEEQLLKLCYE----------------------VLISVKEYHRNPPENGQIKPSAFILDRYGRIT-VSQLCSIEEFKSAQ-SMPRNYECLLYMAPEFFN
|. ..||. |.                       .|.. .          ..| | | | |..     .   | .  .... .  .    .  |||| . 
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---------TVKISDFGLSRDIYDDDQQG-ESKDYYRKKEHKGGKTMLPIRWMAPECI-

GHPIDP---IKADIWSLGVTFYFMAAHCYPFFS------KDAHTYQKLVLKGNYALQSVQ--------CSL-LRSIISKCLDLNPEKRPSIEEMLSLDYF
    .    .| |.|| ||. . .   . .  .      ...    ..| .|..  |           |.  . .|...| . .||.||. .|    ..|
---NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF





Kinase 82699.m00115.AA Ciliate-E2 14-62 24 0.002657 7.17 In-house 1-57 (365) Show / Hide
Range on Protein: 14-62
Range on HMM: 1-57/365
Sequence Identity: 24% (14 aa)

LKISSVIAEGSFGSLILVYSVTEQKNYALKRIQENY---------FLNPIDYMKRIDQ
 |.  .| .|.|||  ..    .||..|.|.|. ..         . . | .||.. .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKK

Kinase 82699.m00115.AA NEK 15-46 29 0.048818 3.44 In-house 2-38 (286) Show / Hide
Range on Protein: 15-46
Range on HMM: 2-38/286
Sequence Identity: 29% (11 aa)

KISSVIAEGSFGSLILVYSVTEQKN-----YALKRIQ
.|  .| .||||.  .| .   .|      |..|.|.
EIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKIN

Kinase 82699.m00115.AA CAMK 19-61 13 0.142915 0.02 In-house 1-96 (425) Show / Hide
Range on Protein: 19-61
Range on HMM: 1-96/425
Sequence Identity: 13% (13 aa)

VIAEGSFGSLILVYSV-TEQ-----------KNYALKRIQ----------------------------------ENYFLNPIDYMKR-------ID
.. .||||   |..   | .           . .| | |                                   .  ... |. ||.       .|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLD

Kinase 82699.m00115.AA Pkinase 14-45 31 0.258114 5.73 Pfam 1-32 (293) Show / Hide
Range on Protein: 14-45
Range on HMM: 1-32/293
Sequence Identity: 31% (10 aa)

LKISSVIAEGSFGSLILVYSVTEQKNYALKRI
..| ..| .||||.  . . . ..| .|.|.|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKII

Kinase 82699.m00115.AA Pkinase 69-116 15 4.866814 1.22 Pfam 67-122 (293) Show / Hide
Range on Protein: 69-116
Range on HMM: 67-122/293
Sequence Identity: 15% (9 aa)

YTYYRLDGYVYMLQDYSPS-----DLYNCLK--LHHNL--TEEQLLKLCYEVLISVK
..... ....|| ..| .      ||.  ..   | ..  .|... . .|..|  ..
DWFED-KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLE