Gene 82699.m00115 (T.vaginalis)
82699.m00115
Species: T.vaginalis
Alias: 82699.m00115, TvagK0159
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
---|---|---|---|---|---|
82699.m00115.AA | Protein | None | 312 | None | Fasta, JSON |
82699.m00115.kin_dom | Protein Kinase Domain | None | 243 | None | Fasta, JSON |
Protein domains of 82699.m00115.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 82699.m00115.AA | Ciliate-E2 | 167-256 | 25 | 5.6e-21 | 68.73 | In-house | 253-365 (365) | Show / Hide |
Range on Protein: 167-256 Range on HMM: 253-365/365 Sequence Identity: 25% (31 aa) YMAPEFFNG--------HPIDPIKADIWSLGVTFYFMAAHCYPFFSKDAHTYQKLVLKGNYALQ-----------------SVQCSLL-RSIISK----C ||||| .|| . |.|||||||..|.| .|| |. ..... .. ..|. .|.| . YMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRM LDLNPEKRPS-IEEMLSLDYF |. .||||.. .|. | .| LQKDPEKRITGWEQILNHPWF |
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Kinase | 82699.m00115.AA | Ciliate-E2-Unclassified | 167-256 | 24 | 3.8e-18 | 59.54 | In-house | 228-352 (352) | Show / Hide |
Range on Protein: 167-256 Range on HMM: 228-352/352 Sequence Identity: 24% (31 aa) YM----APEFFNGHPIDP---IKADIWSLGVTFYFMAAHCYPFFSKDAHT----------------YQKLVLKGNYALQS-------VQCS-----LLRS || ||| . |. | .|.||||||| .|.| |||.... ... ...|. .. . | ... YMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFIND IISKCLDLNPEKRPSIEEMLSLDYF ...|.|. ||.||...|. | .| LLQKMLKKNPNKRITFEQILNHPWF |
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Kinase | 82699.m00115.AA | CAMK | 167-256 | 21 | 1.1e-17 | 52.85 | In-house | 285-425 (425) | Show / Hide |
Range on Protein: 167-256 Range on HMM: 285-425/425 Sequence Identity: 21% (31 aa) YMA-PEFFNG-------------HPIDPIKADIWSLGVTFYFMAAHCYPFFSK-------------DAHTYQKLVLKGNYA-LQSVQCS----------- ||| || .|| .| .. |.|.||.|| |.| ..|| .. . . . ..||.| . YMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWD ------------LLRSIISKCLDLNPEKRPSIEEMLSLDYF .. |.|.| .||||..||. |. . DISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM |
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Kinase | 82699.m00115.AA | ULK | 166-256 | 29 | 1.9e-17 | 58.48 | In-house | 212-324 (324) | Show / Hide |
Range on Protein: 166-256 Range on HMM: 212-324/324 Sequence Identity: 29% (34 aa) LYMAPEFFNGH----PIDPIKADIWSLGVTFYFMAAHCYPFFSKDAHTYQ----KLVLKG--------NYALQSV------QC-SLLRSIISKCLDLNPE |||||. ..|. | . .|.||||||. || | ||||| . ... ||. .| | .| .. . ....|...| ... LYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEK KRPSIEEMLSLDYF .| |.||... | DRISWEEIFNHPWF |
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Kinase | 82699.m00115.AA | ULK | 166-256 | 27 | 3e-17 | 56.85 | In-house | 216-329 (329) | Show / Hide |
Range on Protein: 166-256 Range on HMM: 216-329/329 Sequence Identity: 27% (32 aa) LYMAPEFFNGH----PIDPIKADIWSLGVTFYFMAAHCYPFFSKDAHTYQ-----KLVLKG--------NYALQ------SVQCSL-LRSIISKCLDLNP |||||. ..|. | . |.||||||. || | .||.. . ... ||. .. . || ..|.| ....|...| .. LYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDE EKRPSIEEMLSLDYF ..| |.||... | KDRISWEELFNHPWF |
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Kinase | 82699.m00115.AA | Pkinase | 167-256 | 22 | 5.4e-17 | 61.17 | Pfam | 177-293 (293) | Show / Hide |
Range on Protein: 167-256 Range on HMM: 177-293/293 Sequence Identity: 22% (26 aa) YMAPEFFNGHPIDPIKADIWSLGVTFYFMAAHCYPFFSK------DAHTYQKLVLKGNYALQSVQC---------------------SLLRSIISKCLDL ||||| .|.. .. |.|.||.|...| |. || .. | ...... . .. . . ....|..||.. YMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCK NPEKRPSIEEMLSLDYF .|.|||..|. | ..| DPKKRPTAEQILQHPWF |
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Kinase | 82699.m00115.AA | MARK | 165-256 | 39 | 2.2e-16 | 50.26 | In-house | 169-262 (262) | Show / Hide |
Range on Protein: 165-256 Range on HMM: 169-262/262 Sequence Identity: 39% (37 aa) LLYMAPEFFNGHPIDPIKADIWSLGVTFYFMAAHCYPFF--SKDAHTYQKLVLKGNYALQSVQCSLLRSIISKCLDLNPEKRPSIEEMLSLDYF . ||||| |.. | | |.||||||| ||| ..|| ..| . .| .|.|.| . .|..|.. | .|||.||.||| .. . PPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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S_TKc | 82699.m00115.AA | S_TKc | 14-256 | 21 | 1.2e-15 | 52.58 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 14-256 Range on HMM: 1-231/231 Sequence Identity: 21% (58 aa) LKISSVIAEGSFGSLILVYSVTEQKNYALKRIQENYFLNPIDYMKRIDQISFVKPYTYYRLDGYVYMLQDYSPS---DLYNCLKLHHN------LTEEQL .| .| .|.||. ... . .. .|.|.| . ... |. .|. . || | ... ...|| .| . ||. .| . ..| . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HA LKLCYEVLISVKE------YHRNPPENGQIKPSAFILDRYGRITVSQLCSIEEFKSAQSMPRNYEC--LLYMAPEFFNGHPIDPIKADIWSLGVTFYFMA ...|... .. || .||. ||. | | .| . . | . ||||| . . .. |.|.||.|...| |. RFYMYQICCALEYCHSHGIIHRD------LKPENILLDE--------HIKICDFGLARQL--TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML AHCYPFFSKDAHTYQKLVLKGNYALQSVQCSLLRSIISKCLDLNPEKRPSIEEMLS-------LDYF . . || .. ...|.. . ....|.|||. .|||||.. | | .| CGYPPFP-QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 82699.m00115.AA | CAMKL | 165-256 | 33 | 1.1e-14 | 43.12 | In-house | 197-297 (297) | Show / Hide |
Range on Protein: 165-256 Range on HMM: 197-297/297 Sequence Identity: 33% (34 aa) LLYMAPEFFNG--HPIDPIKADIWSLGVTFYFMAAHCYPFFSK--------DAHTYQKLVLKGNYAL-QSVQCSLLRSIISKCLDLNPEKRPSIEEMLSL . ||||| |.| | | |.||||.||. |.| .|| . .. . . .| | .. | .|..|.| | ||||||.|.. .. PPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNH DYF . PWM |
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Kinase | 82699.m00115.AA | CAMKK-Unclassified | 182-256 | 37 | 9.6e-14 | 40.84 | In-house | 313-392 (392) | Show / Hide |
Range on Protein: 182-256 Range on HMM: 313-392/392 Sequence Identity: 37% (30 aa) KADIWSLGVTFYFMAAHCYPFFSKDAHTYQK-LVLKGNYALQS---VQCS-LLRSIISKCLDLNPEKRPSIEEMLSLDYF |||||||||||| |. | ||..|. . . .... .. . || .. . | |..| ||.|| .|. || ..| KADIWSLGVTFYCMVYHSLPFWHKNLQELFHQMICQKEINFPPQYHPHCSHEFKDLIQKMCDKNPKKRITIDQMLVHPWF |
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Kinase | 82699.m00115.AA | STE | 164-256 | 19 | 3.2e-13 | 43.15 | In-house | 226-359 (359) | Show / Hide |
Range on Protein: 164-256 Range on HMM: 226-359/359 Sequence Identity: 19% (26 aa) CLLYMAPEFFNG------HPIDPIKADIWSLGVTFYFMAAHCYPFFSKDAHTYQKLVLKGNYALQ----------------------------------- . .|||| .. .. | .|.|||||| | || ..|.. . . ...... | TP-WMAPEVIQQNGQGRDKGYD-TKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYP SVQCSLLRSIISKCLDLNPEKRPSIEEMLS--LDYF . . .. |.|||. .|.|||. ...|. . HKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI |
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Kinase | 82699.m00115.AA | NEK | 167-256 | 31 | 3.9e-12 | 39.41 | In-house | 190-286 (286) | Show / Hide |
Range on Protein: 167-256 Range on HMM: 190-286/286 Sequence Identity: 31% (31 aa) YMAPEFFNGHPIDPIKADIWSLGVTFYFMAAH--CYPFFSK--DAHTYQKLVLKG-NYA-LQSVQ-CSL-LRSIISKCLDLNPEKRPSIEEMLSLDYF ||.|| ... | . |.||||||. | |.. || .. . . . . || .|. ..| . | |...||..| .||.|||... |.. . YMSPEVCQNKPYNN-KSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI |
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Kinase | 82699.m00115.AA | TyrKc | 14-256 | 16 | 1.6e-05 | -133.22 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 14-256 Range on HMM: 1-280/280 Sequence Identity: 16% (50 aa) LKISSVIAEGSFGSLIL-VYSVTEQKNYALKRIQENY---FLNPIDYMKRI--DQISFVKPYTYYRLD-------GYVYMLQDYSPS-DLYNCLKLHHN- .. .. || || . ... . | | ..|. |.. . |... . |. | . . . . .... | | || . |. |.. ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK LTEEQLLKLCYE----------------------VLISVKEYHRNPPENGQIKPSAFILDRYGRIT-VSQLCSIEEFKSAQ-SMPRNYECLLYMAPEFFN |. ..||. |. .|.. . ..| | | | |.. . | . .... . . . |||| . LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---------TVKISDFGLSRDIYDDDQQG-ESKDYYRKKEHKGGKTMLPIRWMAPECI- GHPIDP---IKADIWSLGVTFYFMAAHCYPFFS------KDAHTYQKLVLKGNYALQSVQ--------CSL-LRSIISKCLDLNPEKRPSIEEMLSLDYF . .| |.|| ||. . . . . . ... ..| .|.. | |. . .|...| . .||.||. .| ..| ---NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |
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Kinase | 82699.m00115.AA | Ciliate-E2 | 14-62 | 24 | 0.002657 | 7.17 | In-house | 1-57 (365) | Show / Hide |
Range on Protein: 14-62 Range on HMM: 1-57/365 Sequence Identity: 24% (14 aa) LKISSVIAEGSFGSLILVYSVTEQKNYALKRIQENY---------FLNPIDYMKRIDQ |. .| .|.||| .. .||..|.|.|. .. . . | .||.. . YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKK |
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Kinase | 82699.m00115.AA | NEK | 15-46 | 29 | 0.048818 | 3.44 | In-house | 2-38 (286) | Show / Hide |
Range on Protein: 15-46 Range on HMM: 2-38/286 Sequence Identity: 29% (11 aa) KISSVIAEGSFGSLILVYSVTEQKN-----YALKRIQ .| .| .||||. .| . .| |..|.|. EIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKIN |
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Kinase | 82699.m00115.AA | CAMK | 19-61 | 13 | 0.142915 | 0.02 | In-house | 1-96 (425) | Show / Hide |
Range on Protein: 19-61 Range on HMM: 1-96/425 Sequence Identity: 13% (13 aa) VIAEGSFGSLILVYSV-TEQ-----------KNYALKRIQ----------------------------------ENYFLNPIDYMKR-------ID .. .|||| |.. | . . .| | | . ... |. ||. .| TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLD |
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Kinase | 82699.m00115.AA | Pkinase | 14-45 | 31 | 0.258114 | 5.73 | Pfam | 1-32 (293) | Show / Hide |
Range on Protein: 14-45 Range on HMM: 1-32/293 Sequence Identity: 31% (10 aa) LKISSVIAEGSFGSLILVYSVTEQKNYALKRI ..| ..| .||||. . . . ..| .|.|.| YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKII |
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Kinase | 82699.m00115.AA | Pkinase | 69-116 | 15 | 4.866814 | 1.22 | Pfam | 67-122 (293) | Show / Hide |
Range on Protein: 69-116 Range on HMM: 67-122/293 Sequence Identity: 15% (9 aa) YTYYRLDGYVYMLQDYSPS-----DLYNCLK--LHHNL--TEEQLLKLCYEVLISVK ..... ....|| ..| . ||. .. | .. .|... . .|..| .. DWFED-KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLE |