93242.m00133

Species: T.vaginalis
Alias: 93242.m00133, TvagK0223
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
93242.m00133.AA Protein None 316 None Fasta, JSON
93242.m00133.kin_dom Protein Kinase Domain None 241 None Fasta, JSON

Protein domain

Protein domains of 93242.m00133.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 93242.m00133.AA S_TKc 14-254 27 5.2e-66 226.54 SMART 1-231 (231) Show / Hide
Range on Protein: 14-254
Range on HMM: 1-231/231
Sequence Identity: 27% (70 aa)

LECLDVIAIGGYGIIYLVYSHLYKTKFAMKMITKEDFKPIEIQCLMSIDDPHIIRLYQHFKFNDSIYLLMEYCPT---DLEKMLINSKS------ISHDD
 | |..|  |..|  |... .  . ..|.|.|   .    |||.|.. . |.|..|| .|   |..|. ||||..   || ... . ..      ..  .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H

MMRYIQDVILCVRACHQHNIAHCDIKPGNFLIDSYGRIKITDFGMSIIHKQSQNYKSYRGTRLCMAPEIMKKQEYNPIKADIWALGVTIYFMATKRYPFS
  .|.. ... .  ||.|.| |.|.|| | |.|.  .|||.|||.. .       ... ||.  ||||..    |.. |.|.|..|...| |.. . ||.
ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP

ADCIEEKIIQCRYDESLVSDPLLRQVIQSCLNVDPELRFSEDQLLS-------LPYF
    ......         .| ... |. ||..||| | .  ..|         |.|
---QMQMMFKKIG------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 93242.m00133.AA CAMK 19-254 18 4.9e-63 201.68 In-house 1-425 (425) Show / Hide
Range on Protein: 19-254
Range on HMM: 1-425/425
Sequence Identity: 18% (79 aa)

VIAIGGYGIIYLVYSHLYK------------TKFAMKMITK---------------------------------EDFKPIEIQCLMS-------IDDPHI
..  |..|. .|..  . .            .|.|.|.| |                                 ... . ||.....       .| |.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IRLYQHFK------------FNDS--------IYLLM---EYCPT-----DLEKMLINSKS---------------ISHDDMMRYIQDVILCVRACHQHN
|.||...             . .         .|. |   |||.      ||  ...  ..               .. ..  ||.. ..  |. ||.||
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IAHCDIKPGNFLIDSY-----------------GRIKITDFGMSIIHKQ------------------------SQNYKSYRGTRLCMA-PEIMKK-----
|.|.|.|| | |.|.                  . |||.|||.... ..                         | .| . ||   || ||. ..     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------QEYNPIKADIWALGVTIYFMATKRYPFSADC----------------IEEKIIQCRY--DESLVSD----------------------PLLR
        ..| . |.|.|..||  |.| . ..|| .||                . |||....|  ... .|.                      .  .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

QVIQSCLNVDPELRFSEDQLLSLPYF
. |...|.|||| |.. .| |. | .
DLIRKMLQVDPEKRMTIEQCLNHPWM

Pkinase 93242.m00133.AA Pkinase 14-254 25 1.6e-55 195.56 Pfam 1-293 (293) Show / Hide
Range on Protein: 14-254
Range on HMM: 1-293/293
Sequence Identity: 25% (75 aa)

LECLDVIAIGGYGIIYLVYSHLYKTKFAMKMITKEDFKP---------IEIQCLMSIDDPHIIRLYQHFKFNDSIYLLMEYCPT-----DLEKMLI--NS
.... .|  |..|  |. . . .  ..|.| | |.. |.          ||| . ... |.|.|||  |  .|.||. ||||.      ||  ..   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KSI--SHDDMMRYIQDVILCVRACHQHNIAHCDIKPGNFLIDSYGRI----KITDFGMSII--HKQSQNYKSYRGTRLCMAPEIMKKQEYNPIKADIWAL
...  | ..  .|.  ..  .  ||...| |.|.|| |.|||. | |    ||.||| .    .  .. .... ||.  ||||. ....| . |.|.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVTIYFMATKRYPFSAD------CIEEKIIQCRY-----DESLVSD-------------------PLLRQVIQSCLNVDPELRFSEDQLLSLPYF
|...| |...| ||. .      .  ..| . ..     |..  ..                   . ....| .||..||. | . .|.|  |.|
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 93242.m00133.AA CAMKL 34-254 27 2.5e-55 174.97 In-house 20-297 (297) Show / Hide
Range on Protein: 34-254
Range on HMM: 20-297/297
Sequence Identity: 27% (78 aa)

H-LY-KTKFAMKMITKE----DFKPI----------------EIQCLMSID---DPHIIRLYQHFKFNDS------IYLLMEYCPTD---LEKMLINS--
| .. ..| |.|.| |.    | .                  |||......    |.||.||...   .       ||| ||||.     |  ....   
HIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGH

--KSISHDDMMRYIQDVILCVRACHQHNIAHCDIKPGNFLIDSYG--RIKITDFGMSIIHK-Q----SQNYKSYRGTRLCMAPEIMKK--QEYNPIKADI
  .... ..  || . ..  |  ||.|.|.| |||| | |.|. |   |||.|||.|.... .     |  |   |.   ||||| ..  ..|.  |.||
RRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDI

WALGVTIYFMATKRYPFSADCI----------EEKIIQCRYDESLVSDP-LLRQVIQSCLNVDPELRFSEDQLLSLPYF
|..||. |.| . ..|| .|..          ..||... | .   ...  .|. |.. |.|.|| |.. .|... | .
WSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNHPWM

Kinase 93242.m00133.AA AGC 14-254 18 8.7e-51 128.42 In-house 1-395 (395) Show / Hide
Range on Protein: 14-254
Range on HMM: 1-395/395
Sequence Identity: 18% (75 aa)

LECLDVIAIGGYGIIYLVYSH------LYKTKFAMKMITKED---------FKPI--E------------IQCLMSID----------DPHIIR-LYQHF
 | | ||  |..|  |||           .  .|||.. |..          . .  |             . |. ..           | |.. |.  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

KFNDS--IYLLMEYCP---------TDLEKMLINSK-----SISHDDMMRYIQD-------VILCVRACHQ-HNIAHCD-IKPGNFLIDSYGRIKITDFG
. .|   .|..|||.|          ..| .|.. .     . . .    |.         ..|..   |. ..| | | .|| | |.|. | ||.||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

MSIIHKQS---------------------------------------------------QNYKSYRG--TRLCMAPEIMKKQEYNPIKADIWA--LGVTI
.. . ...                                                   .  ..  |  |   |||||     |..  .|.|.  ||. .
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKA-CDWWSFGLGCLM

YFMATKRYPFSAD-------------CIEEKIIQCR----YDESLVSD------------PLLRQVIQSCLNVDPELRFS----------EDQLLSLPYF
| | | . ||..|              . .||. .|     .. . ..            | ..  |. .|..||| |             ... . |.|
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF





Kinase 93242.m00133.AA MARK 119-254 40 1.2e-46 150.63 In-house 120-262 (262) Show / Hide
Range on Protein: 119-254
Range on HMM: 120-262/262
Sequence Identity: 40% (58 aa)

CHQHNIAHCDIKPGNFLIDSYG--RIKITDFGMSIIHKQSQNYKSYRGTRLCMAPEIMKKQEYNPIKADIWALGVTIYFMATKRYPFSADC-----IEEK
||..||.|.|||| | |||. |   |||.|||.||. .  |  ..  ||  .|||||..|..|.  |.|||.|||  ||| . ..|| .|.     ...|
CHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKK

IIQCRYDESLVSDPLLRQVIQSCLNVDPELRFSEDQLLSLPYF
|  ..||      . .|. ||. |.|.|| | . ..... | .
ILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase 93242.m00133.AA Ciliate-E2 14-254 21 8.7e-46 155.15 In-house 1-365 (365) Show / Hide
Range on Protein: 14-254
Range on HMM: 1-365/365
Sequence Identity: 21% (79 aa)

LECLDVIAIGGYGIIYLV--YSH--LY----------------KTK---FAMKMITK---EDFKPIEIQC---------------LMSIDDPHIIRLYQH
 . . .|  |..|..|..  ..   ..                |.|   .|||.. |   | .| .. ..               | ... |.||..| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FK--FNDSIYLLMEYCPT-DLEKMLINS-----------KSISHDDMMRYIQDVIL---------------CVRACHQHN-IAHCDIKPGNFLIDSYGRI
|.   ...||| ||||   ||.. ..|.           |....  . .... ..                ... .|. | | | |||| | |.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KITDFGMSIIHKQS--------------------------------QNYKSYRGTRLCMAPEIMKKQEY--------NPIKADIWALGVTIYFMATKRYP
||.|||.| . ...                                . .... ||   ||||| ....|           |.|||.|||..|.| ....|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FSADCIEEKIIQCRYD------------------ESLVSDPLLRQVIQS----CLNVDPELRFS-EDQLLSLPYF
|     ...|.|| .|                  . .  ..   . |.     .|..||| |..  .|.|  |.|
F-----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 93242.m00133.AA Ciliate-E2-Unclassified 15-254 20 3.3e-42 144.19 In-house 2-352 (352) Show / Hide
Range on Protein: 15-254
Range on HMM: 2-352/352
Sequence Identity: 20% (71 aa)

ECLDVIAIGGYGIIYLVYSHLYKTKF-------AMKMITKEDFKP--------IEIQCLM----------------SIDDPHIIRLYQHFKFNDSIYLLM
. . .|  ||.|..|...    | ..        .... .   .         .|.....                ....|.|.... .|.  . ||. |
KIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYCP-TDLEKMLINSKS-----------------ISHDDMM-----RYIQDVILCVRACHQHN-IAHCDIKPGNFLIDSYG---RIKITDFGMSIIHK--
|||.  ||.... ..|.                 ..   .      .|.  ....   .|. | | | |||| | |.|. |   .|||.||| |.  .  
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

--------------QSQNYKSYRGTRLCM----APEIMKKQEYNP---IKADIWALGVTIYFMATKRYPFSADC-------------------IEEKIIQ
              ..|....  ||   |    |||....|.|.    .|.|||.||| .|.| . .|||.. .                   ....|.|
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

CRYDESL--------VSDPLLRQVIQ----SCLNVDPELRFSEDQLLSLPYF
. .. .          ..|     |.    ..|...|. | . .|.|  |.|
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 93242.m00133.AA Ciliate-E2b 14-254 26 3.1e-38 113.87 In-house 1-272 (272) Show / Hide
Range on Protein: 14-254
Range on HMM: 1-272/272
Sequence Identity: 26% (73 aa)

LECLDVIAIGGYGIIYLVYS-HLYKTKFAMKMITKE--------DFKPIEIQCLMSIDDPHIIRLYQHFKFNDSIYLLMEYCP-TDLEKMLINSK--SIS
..       | .| .||| .    |  .||| | |         .   .|.. |  .. | |..... || ....|..||.|   .|. .... .   .|
MIYIKKLGFGQFGSVYLVWNTKNTKQYYAMKCISKNQIIQQNMEKHMLQEKNVLEKCNHPFIMKFIRSFKDDQHMYFMMEFCNGMELFDVIREIGRLLLS

HDDMMRYIQDVILCVRACHQHNIAHCDIKPGNFLIDSYGRIKITDFGMS-IIHKQSQ----NYKSYRGTRLCMAPEIMK-----KQEYNPIKADIWALGV
  |   ||  ..|| .  |. || . |||| | ..|. | .|. |.| . .. |...    .. . .||   |||||..      . |. .|.|||..|.
TYDSQFYIASICLCLEYLHNQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTF-TIIGTPHYMAPEIIQSLQPGGKGYT-YKVDIWSVGI

TIYFMATKRYPFSADC-----IEEKIIQC--RYD-ESLVSDPLL-RQVIQSCLNVDPELRF--SEDQLLSLPYF
. |..  .. |.  |      | ..||.   . .  |  .| .   . ...||.  ||.|   | ..| | |.|
CLYEFMCGYVPWAEDVQDPYEIYQEIIKKYDEIQFPSYCKDKMADKKLMLQCLQKMPEVRLGGSYSWLKSHPWF

Kinase 93242.m00133.AA ULK 14-254 22 1.2e-35 124.02 In-house 1-324 (324) Show / Hide
Range on Protein: 14-254
Range on HMM: 1-324/324
Sequence Identity: 22% (73 aa)

LECLDVIAIGGYG-IIYLVYSHLY---KTKFAMKMITKEDFKPI---------------EIQCLMSID---DPH--IIRLYQHFKFNDS--IYLLMEYCP
 .  ...  | .|   |  . .     . ..| ||| |  .. .               ||| .  ..    |.  |..||  |.  ..  ||. ||||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

T-DLEKMLI---------NSKSISHDDMMRYIQDVILCVRACHQHNIAHCDIKPGNFLIDSY------------GRIKITDFGMSII-H---KQSQNYKS
  |||. .          . | .| .    .... .   .. |.||| |.|||| | ||               |..||.||| . .     .. | ...
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

YR------GTRLCMAPEIMK----KQEYNPIKADIWALGVTIYFMATKRYPFSADCIEEKI-------------------IQCRYD---ESLVSDPLLRQ
.       || | |||.| .    ...|. .|.||| ||. .| | . .|||... ... .                    . ...   .. .  | ...
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

VIQSCLNVDPELRFSEDQLLSLPYF
 |. .| .|.. |.| ..... | |
LIRRMLQYDEKDRISWEEIFNHPWF

Kinase 93242.m00133.AA ULK 14-254 23 1.2e-34 118.39 In-house 1-329 (329) Show / Hide
Range on Protein: 14-254
Range on HMM: 1-329/329
Sequence Identity: 23% (78 aa)

LECLDVIAIGGYGIIYLVYSHLYK----TKFAMKMIT--KEDFKP-------------IEIQCLMSIDDP--------HIIRLYQHFKFNDS--IYLLME
 .  ...  | .|  |  . .  |     |.| |||   |.. |.              ||. .  ...|        .|..||  |.  ..  ||. ||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCPT-DLEKMLI----------NSKSISHDDMMRYIQDVILCVRACHQHNIAHCDIKPGNFLIDSY------------GRIKITDFGMSII-HKQ---SQ
||.  |||. .           . | .| .    .... .   .. |.||| |.|||| | ||.              |..||.||| .    .     |
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

NYKSYR------GTRLCMAPEIMK----KQEYNPIKADIWALGVTIYFMATKRYPFSAD-CIEE-----KIIQ-------------CRYD---ESLVSDP
 ....       || | |||.| .    ...|.  |.||| ||. .| | . ..||.|  . .      | |.              ...   .. .  |
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISP

LLRQVIQSCLNVDPELRFSEDQLLSLPYF
 ... |. .| .|.. |.| ..|.. | |
ECKDLIRRMLQYDEKDRISWEELFNHPWF

Kinase 93242.m00133.AA CMGC 14-203 16 1.7e-32 103.38 In-house 1-342 (513) Show / Hide
Range on Protein: 14-203
Range on HMM: 1-342/513
Sequence Identity: 16% (58 aa)

LECLDVIAIGGYGIIYLVYS--------------HLYKTKFAMKMITKEDFKP-----------------IEIQCLMSI-----------------DDPH
 |....|  | ||. |  .               | .. . |.| | ..  ..                  ||..|. .                 ....
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IIRLYQHFKFND-----------------SIYLLMEYCPTDLEKMLINSK---------SISHDD------------MMRYI------QDVILCVR--AC
|..|| .|....                 ..|| .||...|| ... | .           |.                 ..      . .. ..    |
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HQHN--IAHCDIKPGNFLIDS--------------------YGRIKITDFGMSI-IHKQ---------------------SQNYKSYRGTRLCMAPEIMK
|.|.  | |.|.|| | ||..                     ||.|| |||..  .|.                      .. | .|  ||   ||||. 
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

KQEYNP---------IKADIWALGVTIYFMATK-------RYPF
  ..            . |.|..|  .. | |.       ..|.
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPL

Kinase 93242.m00133.AA TyrKc 14-254 19 5.5e-12 -28.91 SMART 1-280 (280) Show / Hide
Range on Protein: 14-254
Range on HMM: 1-280/280
Sequence Identity: 19% (57 aa)

LECLDVIAIGGYGIIYL-VYSHLYKTKFAMKMITKEDFKPI-----EIQCLMSI--DDPHIIRLYQHFKFN-------DSIYLLMEYCPT-DLEKMLINS
.. ....  | .|..|. ...    .. | ||. ..    .     |.. ....  . |.|.|||             . ....|||.|  || . | ..
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

KS-ISHDDMMRYIQDVILCVRACHQHNIAHCDIKPGNFLIDSYGRIKITDFGMSIIHKQS-------QNYKSYR--GTR--LC---MAPEIMKKQEYNPI
.  ....|.  .  ..    .  |..|. | |.   | |... ...||.|||.|  ..         . |..    |..  |    |||| ... ... .
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-T

KADIWALGVTIYFMAT---KRYP------FSADCIEEKIIQCRYDESLVS---------DPLLRQVIQSCLNVDPELRFSEDQLLSLPYF
| |.|. ||... . |   . ||       |.. . |.. | .. .   .          . . |....| . ||| | .  ..    .|
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase 93242.m00133.AA MARK 15-87 27 1.1e-08 24.74 In-house 2-85 (262) Show / Hide
Range on Protein: 15-87
Range on HMM: 2-85/262
Sequence Identity: 27% (23 aa)

ECLDVIAIGGYGIIYLVYSHLYKTKFAMKMIT---KED---FKPI--EIQCLMSIDDPHIIRLYQHFK--FNDS-IYLLMEYCP
. | .|  |.|.  .|. ......|.| |..    . |   .|..  ||. ....| |.||.|.. .    .   ||| |||..
KMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYAS

Kinase 93242.m00133.AA Pkinase_Tyr 135-194 28 8e-06 20.44 Pfam 143-205 (270) Show / Hide
Range on Protein: 135-194
Range on HMM: 143-205/270
Sequence Identity: 28% (18 aa)

LIDSYGRIKITDFGMSIIHKQSQNY-KSYRGTRLC---MAPEIMKKQEYNPIKADIWALGVTIY
|... . .||.|||..  .    .| ..  |..|    |||| ..  ... .| |.|. ||...
LVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFT-TKSDVWSFGVLMW

Kinase 93242.m00133.AA CMGC 224-254 35 0.000352 8.61 In-house 483-513 (513) Show / Hide
Range on Protein: 224-254
Range on HMM: 483-513/513
Sequence Identity: 35% (11 aa)

DPLLRQVIQSCLNVDPELRFSEDQLLSLPYF
||...  .. .|  ||. | . .| |. |||
DPQAIDLLKKMLQYDPDKRITAEQALQHPYF