Gene 89348.m00043 (T.vaginalis)

89348.m00043

Species: T.vaginalis
Alias: 89348.m00043, TvagK0200
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
89348.m00043.AA Protein None 307 None Fasta, JSON
89348.m00043.kin_dom Protein Kinase Domain None 244 None Fasta, JSON

Protein domain

Protein domains of 89348.m00043.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 89348.m00043.AA S_TKc 14-257 21 2.5e-33 117.94 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-231/231
Sequence Identity: 21% (56 aa)

LDLVETISSMKCGSVYIIRYPNCEKNYVLKSIPIEKFKQKDYDYMMDSTDVNTTKIYAYESYESNVYILQEFCPN---TVDYMIRRQKY------LNKEL
 .....| .   |.||  |  .  . . .| |.  .  ..  . ..     |  |.| .    ...|.  |.|..   ..  .|.....      ..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H

LVKHSIAIAKAVAQLHHKQKPHLNLKPSNILIDEDETIKLTDFGYPTDDEFGTCENEFLNSLPFLAPEYTSITKQDPY-KADIWALGVIFYMMYTGRIPW
  .    |..|.. .| ..  |  |||.|||.||  .||..|||  .        . |  .. ..|||      .  . |.|.|..|.|.| |..|. |.
ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCGYPPF

DGISKATIAENVLKEEPNLDAIDNKEYADIIGSCLQLNPSDRPSIDDLLN-------VPLF
.    ... ....           .|  |.|  ||| .|..||.. ..|.        | |
P--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 89348.m00043.AA Ciliate-E2 14-257 16 2.8e-29 97.64 In-house 1-365 (365) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-365/365
Sequence Identity: 16% (62 aa)

LDLVETISSMKCGSVYII--RYPNCEKN----------------YVLKSIPIEKFKQKDYDYMMDSTDVN-----------------------TTKIY-A
 .... | .   ||||    .  .....                .  | . .. .|...  ...   ...                         |.| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YES-YESNVYILQEFCPNT--VDYMIRRQKYLNKELL------VKHSIAIAKAVAQ-----------------LHHKQKP---HLNLKPSNILIDEDETI
...  ..|.|.  |.|      ||.. ..|  |.|.        |. . | | ..|                  . ..|    | ..||.|||.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLTDFGY------PTDDEF-----GTCENEF----------------------LNSLPFLAPEYTSITK--------QDPYKADIWALGVIFYMMYTGRI
|..|||.      . ....     . . . .                      . .....|||  .  |        .  ||.|||.||||.|.| .|. 
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PWDGISKATIAENVLKEEPNLD------------------AIDNKEYADIIGS----CLQLNPSDRPS-IDDLLNVPLF
|.         .. .. . ...                      .|  |.|      .|| .|. |.. ....|| | |
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 89348.m00043.AA Ciliate-E2-Unclassified 68-257 20 3.5e-29 98.37 In-house 85-352 (352) Show / Hide 
Range on Protein: 68-257
Range on HMM: 85-352/352
Sequence Identity: 20% (56 aa)

KIYAYESYESNVYILQEFCPN-TVDYMIRRQ-----------------KYLNKELLV-----KHSIAIAKAVAQLHHKQ-KPHLNLKPSNILIDEDE---
| . ..  . |.||  |.|.. .  ..|. .                 | .  .  .     .    | ..  .||||.   | ..||.|||.|..    
KMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNY

TIKLTDFGY-----PTDDEFGTC------------ENEFLNSLPFL----APEYTSITKQDP---YKADIWALGVIFYMMYTGRIPWDGISKAT------
 ||..|||        ...  |              . |  .. ..    |||.    ..|    ||.|||.||||.| | .|. | .. ..        
YIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLIT

----------IAENVLKEEPNLDAIDN--------KEYADIIG----SCLQLNPSDRPSIDDLLNVPLF
          . .| .. ... .  ..        .|..|.|     ..|. ||. |......|| |.|
QWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 89348.m00043.AA CAMK 72-257 17 1.1e-27 85.71 In-house 104-425 (425) Show / Hide 
Range on Protein: 72-257
Range on HMM: 104-425/425
Sequence Identity: 17% (55 aa)

YESYES---------------------NVYILQ---EFCPNT------VDYMIRR--------------QKYLNKELLVKHSIAIAKAVAQLHHKQKPHL
|| ||.                     ..|.     |.|..        || ...               .... .   .    |. ||. .| .   |.
YEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHR

NLKPSNILIDEDE-----------------TIKLTDFGYPTDDEFGTCEN------------------------EFLNSLPFLA-PEYTSI---------
 ||| |||.|...                 .||..|||  .  . |  ..                        .|  .... | ||  .          
DLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNA

----TKQDPYKADIWALGVIFYMMYTGRIPWDGI-------------SKATIAENVLKEEPNLD--AIDN----------------------KEYADIIG
     . ...|.|.|..||| |.| .|. |..|              .   . |...| . . .   ...                      .|  | | 
TDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIR

SCLQLNPSDRPSIDDLLNVPLF
..|| .|..|..|.. || | .
KMLQVDPEKRMTIEQCLNHPWM
Kinase 89348.m00043.AA Pkinase 69-257 21 2.1e-27 97.97 Pfam 66-293 (293) Show / Hide 
Range on Protein: 69-257
Range on HMM: 66-293/293
Sequence Identity: 21% (49 aa)

IYAYESYESNVYILQEFCPN-----TVDYMIR--RQKYL--NKELLVKHSIAIAKAVAQLHHKQKPHLNLKPSNILIDEDETI----KLTDFGYPTD--D
....|. ....|. .|.|..         .|.  |.. .    . . .    |..... .| .   |  |||.|||||.. .|    |..|||       
YDWFED-KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY

EFGTCENEFLNSLPFLAPEYTSI-TKQDPYKADIWALGVIFYMMYTGRIPWDGI------SKATIAENVLKEEPNLDAIDN-------------------
  ..  . |  .....|||      . ...|.|.|..|.|.| |..|| |..|       ..  . ..... ..  |                       
-NNS-MTTFCGTPWYMAPEV-IRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHN

--KEYADIIGSCLQLNPSDRPSIDDLLNVPLF
  .|  |.| .||...|..||.....|. | |
WSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 89348.m00043.AA MARK 129-257 33 4.2e-26 82.46 In-house 130-262 (262) Show / Hide 
Range on Protein: 129-257
Range on HMM: 130-262/262
Sequence Identity: 33% (45 aa)

LKPSNILIDEDE--TIKLTDFGYPTDDEFGTCENEFLNSLPFLAPEYTSITKQDPYKADIWALGVIFYMMYTGRIPWDGIS--KATIAENVLKEEPN-LD
.|| ||||||.    ||..|||. .  . |.  |.|  ..|. ||| ..  . | .|.|||.|||. | | .|. |.|| .    .. ...|....   .
IKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPC

AIDNKEYADIIGSCLQLNPSDRPSIDDLLNVPLF
 .  ||  ..| . |..||..||.|..... | .
HVS-KECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 89348.m00043.AA CAMKL 129-257 29 9.6e-25 75.76 In-house 153-297 (297) Show / Hide 
Range on Protein: 129-257
Range on HMM: 153-297/297
Sequence Identity: 29% (43 aa)

LKPSNILIDEDE--TIKLTDFGYPTD-DEF----GTCENEFLNSLPFLAPEYTSI--TKQDPYKADIWALGVIFYMMYTGRIPWDGIS----KATIAENV
.|| |||.||.   .||..|||  .  ..     |   ..|  |.|. |||  .   .. | .|.|||..||| |.| .|. |.|. .    ...   . 
IKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YL

LKEEPNLDAIDN----K-EYADIIGSCLQLNPSDRPSIDDLLNVPLF
....  .   ..      .  |.| . || ||..||.|....| | .
YWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 89348.m00043.AA STE 65-257 19 1.1e-16 55.56 In-house 91-359 (359) Show / Hide 
Range on Protein: 65-257
Range on HMM: 91-359/359
Sequence Identity: 19% (55 aa)

NTTKIYAYESYE-------SNVYILQEFCP-NTVDYMIR-RQKYLNK------------ELLV-KHSIAIAKA-VAQLHHKQKPHLNLKPSNILIDEDET
|  | | .. .|       ....|  |...  ..| .|. . . ..             | .. .   .| |.  . || ... |  .||.|||.     
NIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----

IKLTDFGYPTDDEF-----------------GTCENEFLNSLPFLAPEYTSITKQDPY------KADIWALGVIFYMMYTGRIPWDGISKATIAENVL--
.||.|||  .  .                  .   | |  .  . |||  .  .|. .      |.||| ||     | ||. ||   .      . .  
VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-RDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFN

--------------KEEPNLDAIDN-------------------KEYADIIGSCLQLNPSDRPSIDDLLN--VPLF
              .. | |                        .|  | |  ||| .|..||. ..||.   | .
YHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 89348.m00043.AA ULK 168-257 24 3.3e-14 46.89 In-house 213-324 (324) Show / Hide 
Range on Protein: 168-257
Range on HMM: 213-324/324
Sequence Identity: 24% (28 aa)

FLAPEYTS----ITKQDPYKADIWALGVIFYMMYTGRIP---WDGISKA---------------TIAENVLKEEPNLDAIDN--KEYADIIGSCLQLNPS
. ||.  .      ... ||.||| ||.||| | .|. |   |   .                 .|  . ..  ..  ....  .|  |.|  .|| ...
YMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPP-KDPKISPECKDLIRRMLQYDEK

DRPSIDDLLNVPLF
|| |.....| |.|
DRISWEEIFNHPWF
Kinase 89348.m00043.AA ULK 168-257 26 1.7e-12 40.01 In-house 217-329 (329) Show / Hide 
Range on Protein: 168-257
Range on HMM: 217-329/329
Sequence Identity: 26% (30 aa)

FLAPEYTS----ITKQDPYKADIWALGVIFYMMYTGRIP---W-DGISKATIAEN----------VLKEEPNLD-----AIDNKEYADIIGSCLQLNPSD
. ||.  .      ... ||.||| ||.||| | .|. |   |     .  | ..          . |. .. .      .  .|  |.|  .|| ...|
YMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKD

RPSIDDLLNVPLF
| |...|.| |.|
RISWEELFNHPWF
Kinase 89348.m00043.AA PEK 79-148 18 2.9e-11 34.73 In-house 358-477 (655) Show / Hide 
Range on Protein: 79-148
Range on HMM: 358-477/655
Sequence Identity: 18% (22 aa)

VYILQEFCP-NTVDYMIRRQK--------------------------------------------YLNKELLVKHSIAIAKAVAQLHHKQKPHLNLKPSN
.||..|.|.  | ...|....                                            ...|... ..   |..... .|...  |  |||||
LYIQMEYCEKKTLRDWIDNNGCPVQFNYWRRNSCKNHYNNYIMNQCCFQSTWSMNMRQWDENNCMFWDKDQCWRIFRQILEGLNYIHSQGMIHRDLKPSN

ILIDEDET-----IKLTDFG
|..| |..     .|  |||
IFLDCDGQHHQMQVKIGDFG
Kinase 89348.m00043.AA PLK-Unclassified 76-148 36 2.3e-10 34.95 In-house 71-151 (264) Show / Hide 
Range on Protein: 76-148
Range on HMM: 71-151/264
Sequence Identity: 36% (30 aa)

ESNVYILQEFCPN-TVDYMIRRQ-------KYLNKELLVK-HSIAIAKAVAQLHHKQKPHLNLKPSNILIDEDETIKLTDFG
..||||| | ||| |.  .|.|        |.|. |. || ..  |..|.  || .   |  ||. ||..... ..|. |||
HENVYILLEYCPNGTLMEYIKRRNFQLFEKKRLT-EYEVKCYTYQIVQALKYLHQNRIIHRDLKLGNIFLNDNMEVKICDFG
Kinase 89348.m00043.AA TyrKc 14-257 20 3.6e-07 -106.8 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-280/280
Sequence Identity: 20% (60 aa)

LDLVETISSMKCGSVYIIRYPNCEKNYVLKSIPIEKFKQKDY----DYMMDS--TDVNTTKIYAYESYE-------SNVYILQEFCP--NTVDYMIRRQK
. | ... .   | ||  ..     .   |..  ..  ..|       |.       |  ..|.. . .         ..|. |..|  .  ||  ....
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

YLNKELLVKHSIAIAKAVAQLHHKQKPHLNLKPSNILIDEDETIKLTDFG-----YPT------DDEFGTCENEFLNS-LPF--LAPEYTSITKQDP---
 |. . |.. .. ||.  . ||.|.  |  |   |.|..|. |.| .|||     |        .|   . | .  .. ||   .|||  .|  ..    
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPE--CI--NYGKFT

YKADIWALGVIFYMMYT-GRIPWDG-----ISKATIAENVLKE-EPNLDAI--------DNKEYADIIGSCLQLNPSDRPSIDDLLNVPLF
 | |.|. ||  . ..| |  |. |     .| . . |.| .   .   .           .|  .|. .| . .|.|||.  ..  . .|
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 89348.m00043.AA PEK 228-257 33 7e-07 19.19 In-house 626-655 (655) Show / Hide 
Range on Protein: 228-257
Range on HMM: 626-655/655
Sequence Identity: 33% (10 aa)

KEYADIIGSCLQLNPSDRPSIDDLLNVPLF
.. ||.|  .|...|..|||....|. ..|
PKQADFIQWMLSHDPQQRPSAQQILQHEFF
Kinase 89348.m00043.AA ULK 126-148 31 9e-06 16.21 In-house 153-187 (329) Show / Hide 
Range on Protein: 126-148
Range on HMM: 153-187/329
Sequence Identity: 31% (11 aa)

HLNLKPSNILIDEDE------------TIKLTDFG
|  .||.||||...             ..|..|||
HRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFG
Kinase 89348.m00043.AA ULK 126-148 31 1.1e-05 16.17 In-house 149-183 (324) Show / Hide 
Range on Protein: 126-148
Range on HMM: 149-183/324
Sequence Identity: 31% (11 aa)

HLNLKPSNILIDEDE------------TIKLTDFG
|  .||.|||| ..             ..|..|||
HRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFG
Kinase 89348.m00043.AA PLK-Unclassified 232-257 38 0.000142 13.36 In-house 239-264 (264) Show / Hide 
Range on Protein: 232-257
Range on HMM: 239-264/264
Sequence Identity: 38% (10 aa)

DIIGSCLQLNPSDRPSIDDLLNVPLF
|.| . |..||. ||.|| ... | .
DLIQHILNWNPDQRPTIDQIMMHPFY
Kinase 89348.m00043.AA PLK-Unclassified 182-200 36 0.01135 6.27 In-house 187-205 (264) Show / Hide 
Range on Protein: 182-200
Range on HMM: 187-205/264
Sequence Identity: 36% (7 aa)

YKADIWALGVIFYMMYTGR
|. |.|..|.| | . .|.
YEVDCWSFGCILYTLLIGK
Kinase 89348.m00043.AA PEK 183-193 54 0.141553 0.37 In-house 574-584 (655) Show / Hide 
Range on Protein: 183-193
Range on HMM: 574-584/655
Sequence Identity: 54% (6 aa)

KADIWALGVIF
|.|...||.||
KVDMYSLGIIF