Gene 84653.m00057 (T.vaginalis)

84653.m00057

Species: T.vaginalis
Alias: TvagK0994, 84653.m00057
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Unique

Sequence

Name Sequence Type Origin Length Description Download
84653.m00057.AA Protein None 630 None Fasta, JSON
84653.m00057.kin_dom Protein Kinase Domain None 170 None Fasta, JSON

Protein domain

Protein domains of 84653.m00057.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 84653.m00057.AA TESK 113-158 34 4.3e-05 11.54 In-house 100-149 (292) Show / Hide 
Range on Protein: 113-158
Range on HMM: 100-149/292
Sequence Identity: 34% (17 aa)

AFGIASGMKYANEEGYFHGDLTTDNIYIS----EDFTPLIHSVGLAKLYG
| .|| ||.|  ..| || |||  |. .     . ..  .   |||.. |
AYDIARGMSYLHSKGVFHRDLTSKNCLVRQRDNNQYEAVVGDFGLARVLG
Kinase 84653.m00057.AA RTKH 108-153 41 0.0001 12.01 In-house 116-161 (276) Show / Hide 
Range on Protein: 108-153
Range on HMM: 116-161/276
Sequence Identity: 41% (19 aa)

KLHNIAFGIASGMKYANEEGYFHGDLTTDNIYISEDFTPLIHSVGL
.|  || |||||| .  |    | ||   |...|    | |   ||
RLCDIAEGIASGMAFVSELRIVHRDLAARNVFVSRRLVPKIGDFGL
Kinase 84653.m00057.AA SrcB 108-156 38 0.000109 11.67 In-house 96-144 (251) Show / Hide 
Range on Protein: 108-156
Range on HMM: 96-144/251
Sequence Identity: 38% (19 aa)

KLHNIAFGIASGMKYANEEGYFHGDLTTDNIYISEDFTPLIHSVGLAKL
||  ..  || || |  .. | | ||   || .||     |   |||..
KLIDMSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARI
Kinase 84653.m00057.AA TK-Sp1 112-154 37 0.000137 12.18 In-house 119-161 (270) Show / Hide 
Range on Protein: 112-154
Range on HMM: 119-161/270
Sequence Identity: 37% (16 aa)

IAFGIASGMKYANEEGYFHGDLTTDNIYISEDFTPLIHSVGLA
|.  ||.|| |  .  |.||||   |. . ..    |   |||
ICRQIARGMEYISKTRYYHGDLAARNVLVGKGLMCKISDFGLA
Kinase 84653.m00057.AA TK 107-143 25 0.00014 10.43 In-house 235-276 (486) Show / Hide 
Range on Protein: 107-143
Range on HMM: 235-276/486
Sequence Identity: 25% (11 aa)

AKLHNIAFGIASGMKYANEE------GYFHGDLTTDNIYISED
. |. ... ||.|| |  .       .. |.|| . |. ..|.
HQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGEN
Kinase 84653.m00057.AA TKL 108-155 22 0.000147 12.35 In-house 133-202 (364) Show / Hide 
Range on Protein: 108-155
Range on HMM: 133-202/364
Sequence Identity: 22% (16 aa)

KLHNIAFGIASGMKYANEEG--------YFHGDLTTDNIYISEDFT--------------PLIHSVGLAK
.....| .||.|| |   ..          | ||...|| . |..|              . |   ||..
QRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSR
Kinase 84653.m00057.AA Ciliate-E4 109-144 33 0.000156 11.63 In-house 109-144 (150) Show / Hide 
Range on Protein: 109-144
Range on HMM: 109-144/150
Sequence Identity: 33% (12 aa)

LHNIAFGIASGMKYANEEGYFHGDLTTDNIYISEDF
. .|||   ..|.|    .  |||| . || ... |
IWQIAFCCINAMYYLQQVNITHGDLKPSNIFFDQYF
Kinase 84653.m00057.AA Jak 107-140 32 0.000185 11.85 In-house 118-151 (299) Show / Hide 
Range on Protein: 107-140
Range on HMM: 118-151/299
Sequence Identity: 32% (11 aa)

AKLHNIAFGIASGMKYANEEGYFHGDLTTDNIYI
....  |..|..||.| .. .| |||. ..||..
DWKMQFAKQICWGMHYLEDKRYIHGDVCARNILV
TyrKc 84653.m00057.AA TyrKc 17-206 14 0.000194 -150.87 SMART 1-280 (280) Show / Hide 
Range on Protein: 17-206
Range on HMM: 1-280/280
Sequence Identity: 14% (42 aa)

LKIVKELRNCKFGSATLAENVLTGQLSIINHVPFSMNV----LK-------------LGRM--VHLAFLPYQGVILQT------DTTQFALVEAATNLTL
..  |.| .. ||   ...                ..|    ||             . .    |   .   ||..|       .   . ..| . .  |
ITLGKKLGEGAFGEVYKGTWK--------------IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDL

TEFIKTLDPSDPAKDAKLHNIAFGIASGMKYANEEGYFHGDLTTDNIYISEDFTPLIHSVGLAKLYGLQ----------------RAN------------
 ....   |    . ..|..... ||.|| |  . .. | || . |. ..|..|  |   ||..  .                   ..            
KDYLRKHRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPEC

----------DVKSYGIIL-ETLFKGGNYTFE--------NDLAQKIKDG-----IVN-----------------------------TFTEICDLL
          || |.|. . | .  |.    .         .. ...|.|       |                             ||.||....
INYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 84653.m00057.AA Frk 111-156 32 0.000228 10.65 In-house 102-147 (260) Show / Hide 
Range on Protein: 111-156
Range on HMM: 102-147/260
Sequence Identity: 32% (15 aa)

NIAFGIASGMKYANEEGYFHGDLTTDNIYISEDFTPLIHSVGLAKL
..|  .|.|| |  .. | | ||   |. . |.    |   |||..
DMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARV
Kinase 84653.m00057.AA SrcA 108-156 36 0.000249 9.08 In-house 96-144 (250) Show / Hide 
Range on Protein: 108-156
Range on HMM: 96-144/250
Sequence Identity: 36% (18 aa)

KLHNIAFGIASGMKYANEEGYFHGDLTTDNIYISEDFTPLIHSVGLAKL
.|  .|  .|.|| |     | | || . || . |     |   |||.|
QLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGENLICKIADFGLARL
S_TKc 84653.m00057.AA S_TKc 17-234 15 0.000275 -114.04 SMART 1-231 (231) Show / Hide 
Range on Protein: 17-234
Range on HMM: 1-231/231
Sequence Identity: 15% (40 aa)

LKIVKELRNCKFGSATLAENVLTGQLS---IINHVPFSMNVLKLGRMVHLAFLPYQGVILQTDTTQFALVEAATN--LTLTEFIKTLDPSDP---AKDAK
 .|....    ||.  .. .. ||..    ||.     .. ... .. |  ..     . |. .  .   | . .   .| ..||   .  .        
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H

LHNIAFGIASGMKYANEEGYFHGDLTTDNIYISEDFTPLIHSV-----GLAKLY---------------GLQR-ANDVKSYGIILETLFKGGNYTFENDL
   ..  |.....|  . |  | ||  .|| ..|        .     |||...               |  . . |. | |.||  ..  |   |.   
ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQLTTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLC-GYPPFP--Q

AQKIKDGIVNTFTEICDLLYQNYSSNYISKLTHFD-----NARNISD-G-----TQFF
 |.. . |.           .   .  |.|. ..|      |  .   .      ..|
MQMMFKKIG----------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 84653.m00057.AA Ciliate-E4 381-400 45 0.16403 1.49 In-house 119-138 (150) Show / Hide 
Range on Protein: 381-400
Range on HMM: 119-138/150
Sequence Identity: 45% (9 aa)

ALSYCHSVGIHHGQLRPDCI
|..|  .|.| || |.|  |
AMYYLQQVNITHGDLKPSNI
Ank 84653.m00057.AA Ank 559-579 42 0.000731 18.19 Pfam 1-21 (33) Show / Hide 
Range on Protein: 559-579
Range on HMM: 1-21/33
Sequence Identity: 42% (9 aa)

DGSTALHAAVLRGNIESIRVL
|| |.|| |...|..| .. |
DGFTPLHLACRCGHTEVVKML
Ank 84653.m00057.AA Ank 526-558 30 0.016576 13.3 Pfam 1-33 (33) Show / Hide 
Range on Protein: 526-558
Range on HMM: 1-33/33
Sequence Identity: 30% (10 aa)

DVCPPLYIAAMNNNVRDIKRLIKSGANPNATAV
| . || .|....... .| |.. ||..||.  
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD