TVAG_137970

Species: T.vaginalis
Alias: TvagK1051, TVAG_137970
External Links:
Annotation:

Classification

Group: PKL
Family: PIK
Subfamily: FRAP

Sequence

Name Sequence Type Origin Length Description Download
TVAG_137970.AA Protein None 2176 None Fasta, JSON
TVAG_137970.kin_dom Protein Kinase Domain None 231 None Fasta, JSON

Protein domain

Protein domains of TVAG_137970.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

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Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase TVAG_137970.AA PIKK 2058-2105 33 6.7e-14 47.31 In-house 243-290 (290) Show / Hide
Range on Protein: 2058-2105
Range on HMM: 243-290/290
Sequence Identity: 33% (16 aa)

KVPFRLTPMFESALGTCGVNGPFRVSMMKYLKSIRHNANSLSPILQFV
|||||||.... |.|..||.|.|| .. . .. .| . ..|  ..  .
KVPFRLTRNMVNAMGPMGVEGVFRRCCEHVMMCMRQHRETLMTVCEVF

Kinase TVAG_137970.AA FATC 2144-2176 39 7.6e-08 28.15 Pfam 1-33 (33) Show / Hide
Range on Protein: 2144-2176
Range on HMM: 1-33/33
Sequence Identity: 39% (13 aa)

TGKDLDTEVDDLIKAATDMNNIAEMPSQWIPWW
.. .    ||.||. ||| .|.. | . | |||
EPLSVEQQVDRLIQEATDPENLCQMYIGWCPWW

Kinase TVAG_137970.AA ATR 2002-2105 18 2.5e-07 20.57 In-house 157-267 (267) Show / Hide
Range on Protein: 2002-2105
Range on HMM: 157-267/267
Sequence Identity: 18% (20 aa)

ANSWLNRVSTFSASTGALSVLSYLFGSVNSGPSDILFEKSTGATTFTAFRVTGES-------QKVPFRLTPMFESALGTCGVNGPFRVSMMKYLKSIRHN
. .|    . .  |. ..... |. |        ||..| .|      . .   |         ||||||   . ..|  . .| ||  .   .. .|..
PQQWYSSRENYCRSYAVWCMVGYIIGLGDRHTDNILIDKINGECVHVDYNCIFNSGEQFEVPEIVPFRLTHNMVFGMGPMKTYGLFRRACEVIMMCMRDH

ANSLSPILQFV
 . .  ...  
RDDIMSVWDCF

PI3Kc TVAG_137970.AA PI3Kc 1892-2172 12 1e-06 -61.16 SMART 1-336 (336) Show / Hide
Range on Protein: 1892-2172
Range on HMM: 1-336/336
Sequence Identity: 12% (43 aa)

SIIYKN----EPSEQFMALIDSFTSFINVE----HRSL-------IQISPGVTLHEILKGHISILDLL-ILYKQNC--------------------GQNP
..|.|.       .  | ..  .      .     |.|       | ..|.  . |  .   ..  .. ...|.                      ..  
AVIFKCGDDLRQDMRMMQMFRLMNKIWQKDKECRRRDLHMRPYKCIPTGPKCGMIEWVPNCETLHQIQKKYHKWKKMPMDYHQWFMFDMLVPEIQKNMY-

ELEILNITQKLDSLQEKEKKIRKIKHLTEGDNKF---TLAKAIFVTSRNAN-SWLNRVSTFSASTGALSVLSYLFGSVNSGPSDILFEKSTGA-------
 ....   ...    . .......|  ..  ..|   .|..    .. ..| .| .....|  |. . .. .|..|     .. |.. . ||        
MMIWHQQACHWMMMYQHMTHMEWLKYFEGATCPFKPPVLYDWFWEHFPDPNEDWWEARDNFTRSCAGYCMVTYILGIGDRHNDNIMLDMKTGHCFHIDFG

TTFTAFRVTGESQ-----KVPFRLTPMFESALG----TCGVNGPFRVSMMKYLKSIRHNANSLSPILQFVLGKTPFADPCLSKS--YVGKYGAETHLN-Q
  |. ...    .     .||||||...  . |      |. | ||  ... .. .|...|..  ...  ..     .||....   . ....  .|. .
HIFGHGPKKPGFKHHHRERVPFRLTHDMVYVMGGGGKPSGYFGYFRTCCCRAYRAMRKHSNLIMNLFEMMVYDP--IMPCWRMMEKDIKYLRQRFRLDHL

DIELLNERIVGTGKDLDTEVDDLIKAATDMNNIAEMPSQW
  |.  ...  |  .    ....    | |.....   | 
SDEEAAQYFMQT-MCTKLIEHSNESWTTRMYWMFHNWAQY

Kinase TVAG_137970.AA FRAP 2058-2102 37 0.000624 10.5 In-house 194-238 (251) Show / Hide
Range on Protein: 2058-2102
Range on HMM: 194-238/251
Sequence Identity: 37% (17 aa)

KVPFRLTPMFESALGTCGVNGPFRVSMMKYLKSIRHNANSLSPIL
|.||||| |   |.  ||..| .|.     .| || . .|.  .|
KIPFRLTRMLVNAMEACGIEGNYRNTCELVMKVIREHKESVMAVL