Gene 85323.m00058 (T.vaginalis)

85323.m00058

Species: T.vaginalis
Alias: 85323.m00058, TvagK0851
External Links:
Annotation:

Classification

Group: Other
Family: Other-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
85323.m00058.AA Protein None 255 None Fasta, JSON
85323.m00058.kin_dom Protein Kinase Domain None 126 None Fasta, JSON

Protein domain

Protein domains of 85323.m00058.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase 85323.m00058.AA Pkinase 111-235 27 1.9e-22 80.47 Pfam 80-213 (293) Show / Hide 
Range on Protein: 111-235
Range on HMM: 80-213/293
Sequence Identity: 27% (39 aa)

PLYRKG----TLTAYIQ--NNPNL--THLELLEKFYQICLDVRNIHNHNIILRDIKPDNILLDEFDKP----HYADFDVS----VFDTDKAYDVTGTRFY
.. ..|     | .||.  .. ..  .  |.   .|||.  .  .|...|| ||.||.|||.|. . .    . .|| ..          .....||..|
EYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWY

MAPEVEQNLFKLK-YVGYGVKSDIFSLGCVLNYMFNHNYPYS
|||||      .. . .|| |.|..|.||.| .|.. . |..
MAPEV------IRGGQYYGPKVDMWSCGCILYEMLCGRPPFP
Kinase 85323.m00058.AA STE 147-240 35 1.1e-19 66.33 In-house 168-274 (359) Show / Hide 
Range on Protein: 147-240
Range on HMM: 168-274/359
Sequence Identity: 35% (40 aa)

IHNHNIILRDIKPDNILLDEFDKPHYADFDVSVFDTD-------------------KAYDVTGTRFYMAPEV-EQNLFKLKYVGYGVKSDIFSLGCVLNY
.|.|.|| |||||.||||        .|| |.   ||                   | . ..||  .||||| .||  . .  ||..|.|| ||||..  
LHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-RDKGYDTKCDIWSLGCTIIE

MFNHNYPYSIYTPL
| . ..|.. ..|.
MATGKPPWHDMHPM
Kinase 85323.m00058.AA Ciliate-E2b 139-234 34 3.4e-18 52.02 In-house 110-210 (272) Show / Hide 
Range on Protein: 139-234
Range on HMM: 110-210/272
Sequence Identity: 34% (35 aa)

QICLDVRNIHNHNIILRDIKPDNILLDEFDKPHYADFDVS-VFDTDKA-----YDVTGTRFYMAPEVEQNLFKLKYVGYGVKSDIFSLGCVLNYMFNHNY
.|||  .  || ||| ||||| ||..|.   .  .|. .. .... .      . . || .|||||. | | .    ||..|.||.|.| .|  .     
SICLCLEYLHNQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFTIIGTPHYMAPEIIQSL-QPGGKGYTYKVDIWSVGICLYEFMCGYV

PY
|.
PW
Kinase 85323.m00058.AA Ciliate-E2-Unclassified 116-235 25 4.2e-18 59.42 In-house 106-271 (352) Show / Hide 
Range on Protein: 116-235
Range on HMM: 106-271/352
Sequence Identity: 25% (44 aa)

GTLTAYIQNNPN-----------------LTHLELL-----EKFYQICLDVRNIHNHN-IILRDIKPDNILLDEFD---KPHYADFDVS-----------
|.|  ||.....                 .|  . .       |.||..    .|  | || |||||.|||.|.     ..  .||  |           
GDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDT

-------VFDTDKAYDVTGTRFYM----APEVEQNLFKLKYVGYG----VKSDIFSLGCVLNYMFNHNYPYS
       ... .......||  ||    ||||      |.  .|.     |.||.|||..| .|   .||..
NQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEV------LQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFY
Kinase 85323.m00058.AA Ciliate-E2 116-234 24 1.2e-17 57.16 In-house 119-296 (365) Show / Hide 
Range on Protein: 116-234
Range on HMM: 119-296/365
Sequence Identity: 24% (45 aa)

GTLTAYIQNN-----------PNLTHLELLEKFYQICL---------------DVRNIHNHN-IILRDIKPDNILLDEFDKPHYADFDVSVFDTDK----
|.|  ||.||            ..|. | .. ..||.                 .. .|. | || |||||.|||.     .  .||  | . .|.    
GDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNR

------------------------------AYDVTGTRFYMAPEVEQNLFKL---KYVGYGVKSDIFSLGCVLNYMFNHNYPY
                              .. . ||  |||||. ..       |  ||. |.||.|||..| .|   ..|.
THKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF
Kinase 85323.m00058.AA AGC 147-224 21 1.5e-17 40.51 In-house 169-295 (395) Show / Hide 
Range on Protein: 147-224
Range on HMM: 169-295/395
Sequence Identity: 21% (30 aa)

IHN-HNIILRD-IKPDNILLDEFDKPHYADFDVSVF-----------------------------------------------------DTDKAYDVTG-
.|. ..|| || .||.||||||    . .||  .                                                       ..|...   | 
LHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGP

-TRFYMAPEVEQNLFKLKYVGYGVKSDIFS--LGCVL
 |  |||||.           ||   |. |  |||..
CTPEYMAPEIL----------YGKACDWWSFGLGCLM
Kinase 85323.m00058.AA CAMK 121-224 23 8.2e-16 46.74 In-house 154-324 (425) Show / Hide 
Range on Protein: 121-224
Range on HMM: 154-324/425
Sequence Identity: 23% (41 aa)

YIQNNPN---------------LTHLELLEKFYQICLDVRNIHNHNIILRDIKPDNILLDEFD-----------------KPHYADFDVS--VFD-----
||. ...               .|  |    | |||  |. .|.|||. ||.||.|||||. .                 .   .||  .  ...     
YIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNF

-------------------TDKAYDVTGTRFYMA-PEVEQNLFKLKY--------------VGYGVKSDIFSLGCVL
                   ..| ... ||  ||| |||      |..               .|| |.|. |.|..|
MCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEV------LNGKGHCNMQNATDEEKPYYGPKCDMWSCGVIL
Kinase 85323.m00058.AA Ciliate-E1 117-218 24 1.2e-15 47.71 In-house 82-202 (202) Show / Hide 
Range on Protein: 117-218
Range on HMM: 82-202/202
Sequence Identity: 24% (30 aa)

TLTAYIQ-------------NNPNLTHLELLEKFYQICLDVRNIHNHNIILRDIKPDNILLDEFDKPHYADFDVSV---FDTDKAYDVTGTRFYMAPEVE
.|. |.|             |. ..| ..... ..|.   .  .|..||| |||||.||| . ...  |.|| .|      ... ....|   |..|. .
SLKDYLQNHNRLEYWQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQ

QN---LFKLKYV-GYGVKSDIF
 |   . . ..   .. ||||.
YNCPEQ-EHNKNQKINYKSDIY
Kinase 85323.m00058.AA C8 144-224 32 1.5e-14 47.02 In-house 136-226 (226) Show / Hide 
Range on Protein: 144-224
Range on HMM: 136-226/226
Sequence Identity: 32% (30 aa)

VRNIHNHNIILRDIKPDNILLDEFDKPH----YADFDVSVF---DTDKAYDVT----GTRFYMAPEVEQNLFKLKYVGYGVKSDIFSLGCVL
| .|| .||. |||||.|.|. .  .       .||... .   . .. ..      ||  |.|||.|.   . .|  |  .||.||.| ||
VNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFAPEIEKK-QDNQYKQYRIQSDLFSVGLVL
Kinase 85323.m00058.AA Ciliate-A1 115-234 26 1.1e-13 42.87 In-house 85-230 (301) Show / Hide 
Range on Protein: 115-234
Range on HMM: 85-230/301
Sequence Identity: 26% (39 aa)

KGTLTAYIQNNPNLTHLELLEKFYQICLDVRNIHNHNIILRDIKPDNILLDEFDKPHYADFDVS-VFDTDK--------------------AYDVTGTRF
.| |  |. .|  .   |  |  |||   .  || |||. ||.||.|||. . ||   .|.  | .    .                         |.. 
YGNLFNYCYQNDYMKKEEIYEICYQIIEGYADIHDHNILHRDLKPQNILIHFDDKWKICDLGMSKQLEQNQDCCDDVNGCSFSKQVNKHYHTCKKGGNLY

YMAPEVEQNLF---KLKYVGYGVKSDIFSLGCVLNYMFN--HNYPY
||.||  |  .   ...    . .||..||||..    .     ||
YMSPEQYQMHYRDQMFIENKIYKQSDMYSLGCIICFLCYKEDSHPY
Kinase 85323.m00058.AA Ciliate-C8 144-224 28 2.2e-13 44.57 In-house 132-238 (238) Show / Hide 
Range on Protein: 144-224
Range on HMM: 132-238/238
Sequence Identity: 28% (30 aa)

VRNIHNHNIILRDIKPDNIL--LDEFDKPH--YAD------FDVSVFDTDKAY-----DVTGTRFY-----------MAPEVEQNLFKLKYVGYGVKSDI
| ..| .||. |||||.|.|  .|. . |    .|      |. . . ..         . ||  |           .|||||..  . ..  .  |||.
VNYLHCFNIMHRDIKPHNFLVCFDQQYQPTIKLCDFKKQCDFGFASQLPKNKSHYHSKKFKGTDQYIEMYFCGNWGYFAPEVEKKQSRIQSDIFSKKSDS

FSLGCVL
.|.| ||
YSVGLVL
S_TKc 85323.m00058.AA S_TKc 48-252 20 7e-10 -32.03 SMART 1-231 (231) Show / Hide 
Range on Protein: 48-252
Range on HMM: 1-231/231
Sequence Identity: 20% (53 aa)

PRGFKVLGYGAHSVVLHSDEFFSSHIF---KFSKLDLSVENKIKE-----ILGILIYYPNLAVPNKYFTSSPLYRK--GTLTAYIQNNPN------LTHL
 .  ...| || ..|    .  . .|.   . .  ..  | .| .     |  .. .. .    ....    .     |.|  ||....       ..  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-EHIRREIQILKKHHPNIVKLYDVFQD----DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-

ELLEKFYQICLDVRNIHNHNIILRDIKPDNILLDEFDKPHYADFDVSVFDTDKAYDVTGTRFYMAPEVEQNLFKLKYVGYGV-KSDIFSLGCVLNYMFNH
.    .||||. .  .|.|.|| ||.||.||||||      .|| .. .     . . ||..||||||          |||  |.|. |.||.|  |.  
HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---------GYGKCKCDWWSCGCILYEMLCG

NYPYSIYTPLIPKKVIY-------------------------L-------IDFM
  |..  ..    |.|                                    ..
YPPFP--QMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF