Gene 93444.m00159 (T.vaginalis)
93444.m00159
Species: T.vaginalis
Alias: 93444.m00159, TvagK0784
External Links:
Annotation:
Group:
CAMK
Family:
CAMK-Tvag1
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| 93444.m00159.AA | Protein | None | 201 | None | Fasta, JSON |
| 93444.m00159.kin_dom | Protein Kinase Domain | None | 139 | None | Fasta, JSON |
Protein domains of 93444.m00159.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 93444.m00159.AA | Ciliate-E2-Unclassified | 29-149 | 20 | 4e-16 | 52.44 | In-house | 100-272 (352) | Show / Hide |
Range on Protein: 29-149
Range on HMM: 100-272/352
Sequence Identity: 20% (36 aa)
MDYIPGVTLESLLRN---------------HKRIRL-----------LYILEIITALNLQLKKMGEKGIKHRDLKPGNIVIDAD---FVPHILDWDDVT-
|.|..| .|. ... ..| .. |. .|. .|. .| ..| |||.|| ||..| . . . | |.
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHK---NNIIHRDIKPENILFDNNGKNYYIKIIDFGISKK
------------TGVSMTQSPYH----GTIRFA----APEIFEM-KKE----CASDIFSFGGIIFNMLTGKAPFDD
. ..... ||... |||... . . ..||.|.| |.. ||.|. ||.|
YQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYD
|
|||||||||
| Kinase | 93444.m00159.AA | Ciliate-E2 | 29-198 | 18 | 9.7e-15 | 47.0 | In-house | 113-304 (365) | Show / Hide |
Range on Protein: 29-198
Range on HMM: 113-304/365
Sequence Identity: 18% (44 aa)
MDYIPGVTLESLLRNHKRIRL------LYILEIITA-LNLQLKK-------------------MGEKG-IKHRDLKPGNIVIDADFVPHILDWD------
|.|. | .|.....|.| |. .|. | . . |. . . .|. | |||.|| ||.. . | |.
MEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYD
---------------------DVTTGVS------MTQSPYHGTIRFAAPEIFEMKKE----------CASDIFSFGGIIFNMLTGKAPFDDVYNNLDYIF
..|.| . ... . || . ||||...||. ..||.|.| |.. ||.|| ||
DDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF-----------
HFIPEEYDVEDVDEQEEDEYEQEDDEDKEKKVKKINKKNK
...|..|
--------------------------------QQQIKQCK
|
|||||||||
| Kinase | 93444.m00159.AA | CAMK | 68-166 | 16 | 1.2e-10 | 29.82 | In-house | 197-372 (425) | Show / Hide |
Range on Protein: 68-166
Range on HMM: 197-372/425
Sequence Identity: 16% (29 aa)
EKGIKHRDLKPGNIVIDAD-----------------FVPHILDWDDVTTGVS-------------------------MTQSPYHGTIRFAA-PEIFEMK-
...| |||||| || .| . . | |. . . . . || ..| ||... |
SHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKG
--------------KECASDIFSFGGIIFNMLTGKAPFDDVY-------------------NNLDYIFHFIPEEYD
..|. | | | . ||.|. ||.. . . . ..|.|.. .
HCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFS
|
|||||||||
| Kinase | 93444.m00159.AA | Pkinase | 68-149 | 30 | 4.3e-10 | 36.78 | Pfam | 126-214 (293) | Show / Hide |
Range on Protein: 68-149 Range on HMM: 126-214/293 Sequence Identity: 30% (28 aa) EKGIKHRDLKPGNIVIDADFVP----HILDWDDVT---TGVSMTQSPYHGTIRFAAPEI--FEMKKECASDIFSFGGIIFNMLTGKAPFDD ..|| |||||| || || . .. .| |. . . . . ||....|||. . . ..|..|.| |.. ||.|. ||.. SMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPG |
|||||||||
| Kinase | 93444.m00159.AA | TKL | 69-170 | 17 | 2.7e-08 | 25.97 | In-house | 159-310 (364) | Show / Hide |
Range on Protein: 69-170
Range on HMM: 159-310/364
Sequence Identity: 17% (27 aa)
KGIKHRDLKPGNIVIDADFV--------------PHILDWDDVTTGVSMTQSPY---------------------HGTIRFAAPEIFEMK--KECAS---
..| |||||. || .| .. . | | .. .... ||.|. |||..... ....
PPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGID
------------DIFSFGGIIFNMLTGKAPFDDVYNNLDYIFHFIPEEYDVEDV
|..||| ... .||.. |..| .. .... .| . . |
EFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQD-P-FEEMFMMV
|
|||||||||
| Kinase | 93444.m00159.AA | CAMK-Tt | 108-151 | 41 | 4e-08 | 23.6 | In-house | 297-342 (396) | Show / Hide |
Range on Protein: 108-151 Range on HMM: 297-342/396 Sequence Identity: 41% (19 aa) YHGTIRFAAPEIFEMKK--ECASDIFSFGGIIFNMLTGKAPFDDVY | ||. | |||||. |. | | | . || |. ||. | YTGTVAFSAPEIFNEDCCYDETIDMWSAGCILYTMLCGQEPFQAEY |
|||||||||
| S_TKc | 93444.m00159.AA | S_TKc | 1-200 | 17 | 5.1e-08 | -59.28 | SMART | 16-220 (231) | Show / Hide |
Range on Protein: 1-200
Range on HMM: 16-220/231
Sequence Identity: 17% (42 aa)
MEGFKIP--------------------LA------PKFFDTSVKHPGEPFDWVLMDYIPG--VTLESLLRNHKR------IRLLYILEIITALNLQLKKM
. . .. | |..|. . . .. |.|..| .| .......| . . .. . . |. .
YKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQD----DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYC
GEKGIKHRDLKPGNIVIDADFVPHILDWDDVTTGVSMTQSPYHGTIRFAAPEIFEMKKEC-ASDIFSFGGIIFNMLTGKAPFDDVYNNLDYIFHFIPEEY
..|| |||||| || .| . | | . . . || . |||.. . . ..|. |.| |.. ||.|. ||. ... .|. |
HSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG---
DVEDVDEQEEDEYEQEDDEDKEKKVKKINKKNKK--------R
..| |. ..|. .|. . .
----------------SPEAKD-FIRKCLQKDPEKRPTAEALQ
|
|||||||||
| Kinase | 93444.m00159.AA | MSK | 107-147 | 31 | 4.4e-07 | 19.99 | In-house | 164-210 (277) | Show / Hide |
Range on Protein: 107-147 Range on HMM: 164-210/277 Sequence Identity: 31% (15 aa) PYHGTIRFAAPEIFEM---KKE---CASDIFSFGGIIFNMLTGKAPF .. .|. ..|||. . ... | |..| | | . ||||. || SPCFTLHYMAPEMLRRGYAQDGGYDEACDWWSLGVILYTMLTGQVPF |
|||||||||
| Kinase | 93444.m00159.AA | RIPK | 100-158 | 25 | 2e-06 | 18.23 | In-house | 174-239 (290) | Show / Hide |
Range on Protein: 100-158 Range on HMM: 174-239/290 Sequence Identity: 25% (17 aa) GVSMTQSPYHGTIRFAAPEIFE--MKKE-----CASDIFSFGGIIFNMLTGKAPFDDVYNNLDYIF . ||. . ||. . .|| |. || ..|. ||. ... ||.| |. |. . . ... VYSMKSKNRWGTLSYMPPEHFRTDNKKPIKVVTPKYDVYSFAIVMWEVLTQKHPYEDRKCMMMIMM |
|||||||||
| Kinase | 93444.m00159.AA | CAMKL | 110-161 | 33 | 7e-06 | 14.59 | In-house | 195-255 (297) | Show / Hide |
Range on Protein: 110-161 Range on HMM: 195-255/297 Sequence Identity: 33% (21 aa) GTIRFAAPEIFEM--KKEC--ASDIFSFGGIIFNMLTGKAPFDDVYN------NLDYIFHFI |. ..|||||. |. . . || | | | ..|..|. |||| . | | .. | GSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKI |
|||||||||
| Kinase | 93444.m00159.AA | AGC | 110-149 | 36 | 1e-05 | 9.19 | In-house | 267-307 (395) | Show / Hide |
Range on Protein: 110-149 Range on HMM: 267-307/395 Sequence Identity: 36% (16 aa) G--TIRFAAPEIFEMKKECASDIFS--FGGIIFNMLTGKAPFDD | | . ||||. | |. | .| ... ||||. || . GPCTPEYMAPEIL---YGKACDWWSFGLGCLMYEMLTGYPPFYG |
|||||||||
| Kinase | 93444.m00159.AA | Ciliate-E2b | 28-86 | 24 | 1.6e-05 | 12.94 | In-house | 78-138 (272) | Show / Hide |
Range on Protein: 28-86 Range on HMM: 78-138/272 Sequence Identity: 24% (15 aa) LMDYIPGVTLESLLRNHK--RIRLLYILEIITALNLQLKKMGEKGIKHRDLKPGNIVIDAD .|... | |....|. . . . .| . | |. ...| .||.|| || .| . MMEFCNGMELFDVIREIGRLLLSTYDSQFYIASICLCLEYLHNQNIIYRDIKPENIMVDHK |
|||||||||
| Kinase | 93444.m00159.AA | AGC | 68-86 | 57 | 3.8e-05 | 7.68 | In-house | 171-191 (395) | Show / Hide |
Range on Protein: 68-86 Range on HMM: 171-191/395 Sequence Identity: 57% (12 aa) E-KGIKHRD-LKPGNIVIDAD . .|| ||| ||| ||..|.| SHMGIIHRDYLKPENILLDED |
|||||||||
| Kinase | 93444.m00159.AA | Ciliate-E2b | 110-166 | 26 | 7.3e-05 | 10.89 | In-house | 167-229 (272) | Show / Hide |
Range on Protein: 110-166 Range on HMM: 167-229/272 Sequence Identity: 26% (17 aa) GTIRFAAPEIFE-----MKK-ECASDIFSFGGIIFNMLTGKAPFDDVYNNLDYIFHFIPEEYD || . |||| . | ...||.|.| . . .. |. |.. . | .| ..|| GTPHYMAPEIIQSLQPGGKGYTYKVDIWSVGICLYEFMCGYVPWAEDVQDPYEIYQEIIKKYD |
|||||||||
| Kinase | 93444.m00159.AA | APH | 37-100 | 22 | 0.000205 | 15.94 | Pfam | 134-205 (248) | Show / Hide |
Range on Protein: 37-100 Range on HMM: 134-205/248 Sequence Identity: 22% (16 aa) LESLLRNHKRIRLLY---ILEIITALNLQLKKMGE-KGIKHRDLKPGNIVID--ADFVPH--ILDWDDVTTG |.. .|.. ... ..... | .|... .. |.|..|||...| .| . ..||||.. | LMDWCRCWVDPEWFDEDRQWWLWQRLWAWLEAHWPPPCWCHGDFHPGNVMWDPRPDGGRVTGVIDWDDACWG |
|||||||||
| Kinase | 93444.m00159.AA | CAMKL | 68-86 | 52 | 0.000234 | 9.65 | In-house | 145-163 (297) | Show / Hide |
Range on Protein: 68-86 Range on HMM: 145-163/297 Sequence Identity: 52% (10 aa) EKGIKHRDLKPGNIVIDAD ..|| |||.|| || .| . SHGIVHRDIKPENILLDEN |
|||||||||
| Kinase | 93444.m00159.AA | RIPK | 73-87 | 66 | 0.000351 | 10.11 | In-house | 132-146 (290) | Show / Hide |
Range on Protein: 73-87 Range on HMM: 132-146/290 Sequence Identity: 66% (10 aa) HRDLKPGNIVIDADF ||||||.|| .|..| HRDLKPENILVDNNF |
|||||||||
| Kinase | 93444.m00159.AA | MSK | 26-81 | 33 | 0.005238 | 6.0 | In-house | 77-132 (277) | Show / Hide |
Range on Protein: 26-81 Range on HMM: 77-132/277 Sequence Identity: 33% (19 aa) WVLMDYIPGVTLESLLRNHKRIRLLYILEIITALNLQLKKMGEKGIKHRDLKPGNI . |.|. | | .| .. .. .|. | . .. | .||| |||||| || YLVMEYCNGGELFTHIRKREHFDESECRMIMRELVMAVDHMHQKGIIHRDLKPENI |
|||||||||
| Kinase | 93444.m00159.AA | CAMK-Tt | 66-86 | 52 | 0.038886 | 2.5 | In-house | 240-260 (396) | Show / Hide |
Range on Protein: 66-86 Range on HMM: 240-260/396 Sequence Identity: 52% (11 aa) MGEKGIKHRDLKPGNIVIDAD | |. . |||||| || . | MHENYVCHRDLKPNNILCNED |
|||||||||