Gene 86997.m00243 (T.vaginalis)

86997.m00243

Species: T.vaginalis
Alias: 86997.m00243, TvagK0960
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
86997.m00243.AA Protein None 302 None Fasta, JSON
86997.m00243.kin_dom Protein Kinase Domain None 197 None Fasta, JSON

Protein domain

Protein domains of 86997.m00243.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 86997.m00243.AA Ciliate-E2 49-227 16 1.5e-17 56.77 In-house 58-350 (365) Show / Hide 
Range on Protein: 49-227
Range on HMM: 58-350/365
Sequence Identity: 16% (48 aa)

KNQQIFENMTKALNLVH----------------HKNIIKMYESFT--ENGNYFIVHNTYSTKNLEQ------ICPLPK---------EEVCMYSLQILS-
.. ...... . .. ..                |.|||||||.|    . |...|   .. ..|..      .. . .         .|.. .. |||. 
NQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQG

--------------AIEALHNAG-IYISNLNPKNIYFDRFGLVKIVDFKD----------------CFLMPKRF------------------CSKFAVTT
              |.| ||. . |   .. | || |     .||.||                  | ...  .                     .. | 
FKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTP

PRPAPELVEQTPY--------NPRSADLWNFGIVLFFLVNGRYPFHECKNID-------------------------TYKTEIQDLLK-----LLDSNEE
.  ||| ..  .|           ..|.| .|..|.... |..|| . ....                             | .||.|     .|. ..|
GYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF-QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPE
Kinase 86997.m00243.AA CAMKL 169-251 25 1.2e-15 46.25 In-house 201-291 (297) Show / Hide 
Range on Protein: 169-251
Range on HMM: 201-291/297
Sequence Identity: 25% (24 aa)

APELVEQ--TPYNPRSADLWNFGIVLFFLVNGRYPFHEC-------KNIDTYKTEIQDLLKLLDSNEEM-LHRDAIKGLLQLDPFDRPKLEDV
|||...   .||. . .| |  |..|...| |..|| .        .|| ... .|  . .  .   ..   || |...|| .| .||.....
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQI
Kinase 86997.m00243.AA Ciliate-E2-Unclassified 66-218 21 1.4e-15 50.56 In-house 80-287 (352) Show / Hide 
Range on Protein: 66-218
Range on HMM: 80-287/352
Sequence Identity: 21% (45 aa)

HKNIIKMYESFTENGNYFIVHNTYSTKNLEQIC---------------------PLPKEEVC-----MYSLQILSAIEALHNAG-IYISNLNPKNIYFDR
| .|.||.. |.   | .||      ..|.|..                      .. ....      |  |||...| ||  . |   .. | || || 
HPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDN

FG---LVKIVDFKDCF-----------------LMPKRFCSKFAVTTP-RP---APELVEQTPYNPR---SADLWNFGIVLFFLVNGRYPFH--ECKNID
 |    .|| ||  .                    ..  .. |. |    |   |||. ..  |. .   ..| | .|..|.... |.|||    |.  .
NGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQ

TYKTEIQDL
...|... .
QLITQWI-N
Kinase 86997.m00243.AA GIN4 63-257 26 1.9e-15 45.42 In-house 90-293 (293) Show / Hide 
Range on Protein: 63-257
Range on HMM: 90-293/293
Sequence Identity: 26% (55 aa)

LVHHKNIIKMYESFTENGNYFIVHNTYSTKNLEQI----CPLPKEEVCMYSLQILSAIEALHNAGIYISNLNPKNIYFDRFGL-VKIVDFKDCFLMPKRF
|. | |....|. . .| . ..|        | ..     |||  |   |  ||.  .   |  .|    | | |.  |..   .|| ||    |  .  
LISHPNVMRLYDVWETNNDLYLVLEYAEKGELFNYLVDHGPLPEREAIHYFRQIIIGVSYCHAFNICHRDLKPENLLLDHKYNRIKIADFGMAALETDNK

CSKFAVTTPR-PAPELVEQTPYNPRSADLWNFGIVLFFLVNGRYPFHEC-KNIDTYKTEIQDLLKLLDSNEEMLH--RDAIKGLLQLDPFDRPKLEDVNR
  . .   |   |||.|   ||.  ..| |  |..|| |. |. || |   || .    .|     . |..|.    .| |. .| .||  | |  |. .
LLETSCGSPHYAAPEIVMGIPYHGFASDVWSCGVILFALLTGHLPFDEEDGNIRKLLLKVQKGKYEMPSDDEISREAQDLIRKILVVDPEKRIKTRDILK

CFGL
   .
HPLI
Kinase 86997.m00243.AA CAMK 169-251 15 5.9e-14 40.66 In-house 288-419 (425) Show / Hide 
Range on Protein: 169-251
Range on HMM: 288-419/425
Sequence Identity: 15% (21 aa)

APELVEQ-------------TPYNPRSADLWNFGIVLFFLVNGRYPFHECKNIDTYK-----TEIQDLLKLLDSNE-EML--------------------
|||....              || ....| |  |..|.... |..|| . .. ....     .....|..   . . ..                     
APEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDIS

----------HRDAIKGLLQLDPFDRPKLEDV
           .| |...|| || .|...|..
DEFHHFVSQECKDLIRKMLQVDPEKRMTIEQC
Kinase 86997.m00243.AA SNRK 108-257 28 3e-13 39.48 In-house 104-254 (254) Show / Hide 
Range on Protein: 108-257
Range on HMM: 104-254/254
Sequence Identity: 28% (44 aa)

YSLQILSAIEALHNAGIYISNLNPKN-IYFDRFGLVKIVDFK-DCFLMPKRFCSKFAVTTPRPAPELVEQTPYNPRSADLWNFGIVLFFLVNGRYPFHEC
|  ||. ||.  |   .    | | | ..|.. |.||. ||      || .    .       |||..    |     |.|  |..|. || |. ||.| 
YFCQIMHAIDYCHQLHVVHRDLKPENVVFFEKQGMVKLTDFGFSNKFMPGEKLETSCGSLAYSAPEILLGDSYDAPAVDIWSLGVILYMLVCGQAPFQEA

KNIDTYKTEIQDLLKLLDSNEEMLHRDAIKGLLQLDPFDRPKLEDVNRCFGL
 . .|  | | |    . .      || |. .|. ||  |  ||..     .
NDSETL-TMIMDCKYTVPDHVSDECRDLIQSMLVRDPKKRASLEEIVSHSWV
S_TKc 86997.m00243.AA S_TKc 2-255 20 1.5e-12 7.22 SMART 1-231 (231) Show / Hide 
Range on Protein: 2-255
Range on HMM: 1-231/231
Sequence Identity: 20% (58 aa)

YVDISE---------WSMIVDK--RNYTIKNIVRQDNESSLVELVNHARSQTFFCTVTKNQQIFENMTKALNLVHHKNIIKMYESFTENGNYFIVHNTYS
|  . .         .  .  |  | . || |                             . ...  . |   ||.||.|.|..| . .....|    .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------------------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCD

T--KNLEQICP----------LPKEEVCMYSLQILSAIEALHNAGIYISNLNPKNIYFDRFGLVKIVDFKDCFLMPKRFCSKFAVTTPRPAPELVEQTPY
.   .| ..            .|  ... |  ||..|.| .|. ||    | | || .|.   .|| ||  . ..     . | .|    |||..   .|
GDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GY

NPRSADLWNFGIVLFFLVNGRYPFHECKNIDTYKTEIQDLLKLLDSNEEMLHRDAIKGLLQLDPFDRPKLEDVNR---------CF
.....| | .|..|. .. |. ||.          ..| ..|..        .| |...|| || .||   .. .          |
GKCKCDWWSCGCILYEMLCGYPPFP----------QMQMMFKKIG---SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 86997.m00243.AA MARK 169-212 36 5.1e-12 35.75 In-house 173-218 (262) Show / Hide 
Range on Protein: 169-212
Range on HMM: 173-218/262
Sequence Identity: 36% (17 aa)

APELVEQTPYNPRSADLWNFGIVLFFLVNGRYPFHECK--NIDTYK
|||.... ||. . .| |  |.||.|.| |..|| ..   . . ||
APEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYK
Kinase 86997.m00243.AA Ciliate-C1 169-204 41 2.8e-10 22.33 In-house 228-263 (328) Show / Hide 
Range on Protein: 169-204
Range on HMM: 228-263/328
Sequence Identity: 41% (15 aa)

APELVEQTPYNPRSADLWNFGIVLFFLVNGRYPFHE
|||| |. .|.  . |.  .|..|| .|.|  |||.
APELHEKQRYCGSKVDIFACGVILFCMVHGHPPFHK
Kinase 86997.m00243.AA ULK 169-245 24 8.8e-10 30.41 In-house 219-317 (329) Show / Hide 
Range on Protein: 169-245
Range on HMM: 219-317/329
Sequence Identity: 24% (25 aa)

APELVE----QTPYNPRSADLWNFGIVLFFLVNGRYPFHECKNIDTYKTEIQDLLKL------------LD---------SNEEMLHRDAIKGLLQLDPF
||....    | ||.   .|.| .|.... .. |..|| .. . |.|.  ||.|...            |.           .|.  .| |...|| |. 
APQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPEC--KDLIRRMLQYDEK

DR
||
DR
Kinase 86997.m00243.AA MELK 60-204 27 1.9e-09 28.15 In-house 50-202 (254) Show / Hide 
Range on Protein: 60-204
Range on HMM: 50-202/254
Sequence Identity: 27% (43 aa)

ALNLVHHKNIIKMYESFTENGNYFIVHNTYSTKNLEQIC----PLPKEEVCMYSLQILSAIEALHNAGIYISNLNPKNIYFDRFGLVKIVDFKDCFLMPK
||  ..|..| ..|     .  .|.| .  .  ..         |  ||  ..  ||.|||  .|  |    .| | |. ||    .|..||  |    |
ALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEETRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKT-K

RFCSKFAVTT-----PRPAPELVEQTPYNPRSADLWNFGIVLFFLVNGRYPFHE
    .  . |        ||||..   |    ||.|  ||.|. |. |  || .
GRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFLPFDD
Kinase 86997.m00243.AA Pkinase 59-124 20 5.4e-08 29.35 Pfam 52-129 (293) Show / Hide 
Range on Protein: 59-124
Range on HMM: 52-129/293
Sequence Identity: 20% (16 aa)

KALNLVHHKNIIKMYESFTENGNYFIVHNTYSTK----NLE------QICPL--PKEEVCMYSLQILSAIEALHNAGI
. .. ..|.||...|..|...... .|            |       . ...  . .|...| .|||...| .|. ||
QIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGI
Kinase 86997.m00243.AA Pkinase 169-246 20 8.4e-05 18.06 Pfam 179-282 (293) Show / Hide 
Range on Protein: 169-246
Range on HMM: 179-282/293
Sequence Identity: 20% (22 aa)

APELVEQTPYNPRSADLWNFGIVLFFLVNGRYPFHEC----KNIDTYKTEIQDLLKLLDSNEE-----------------------MLHRDAIKGLLQLD
|||..   .| ....| | .|..|. ...|| || ..    . .| ..   ... . |.....                          .| ||..|..|
APEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKD

PFDRP
| .||
PKKRP
Kinase 86997.m00243.AA CAMKL 61-85 23 0.000987 7.62 In-house 66-99 (297) Show / Hide 
Range on Protein: 61-85
Range on HMM: 66-99/297
Sequence Identity: 23% (8 aa)

LNLVH---HKNIIKMYESFTENGN------YFIV
. ...   |.||||.|| ..   .      ...|
MKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV
Kinase 86997.m00243.AA CAMK 61-85 15 0.018804 2.91 In-house 85-135 (425) Show / Hide 
Range on Protein: 61-85
Range on HMM: 85-135/425
Sequence Identity: 15% (8 aa)

LNL-------VHHKNIIKMYESFTENGN-------------------YFIV
...       ..|.||||.|| .  . .                   ...|
MKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMV
Kinase 86997.m00243.AA MARK 61-85 17 0.029813 3.36 In-house 53-80 (262) Show / Hide 
Range on Protein: 61-85
Range on HMM: 53-80/262
Sequence Identity: 17% (5 aa)

LNLVHHKNIIKMYESFT--ENGN-YFIV
. ...|.||||... .   ....  ...
MKKLDHPNIIKLFHVIEQDTEQHQIYLI
Kinase 86997.m00243.AA ULK 65-85 39 0.102538 1.87 In-house 76-98 (329) Show / Hide 
Range on Protein: 65-85
Range on HMM: 76-98/329
Sequence Identity: 39% (9 aa)

HHKNIIKMYESFTEN--GNYFIV
||.||.|.|. | .    |..|.
HHPNIVKLYDWFETSNHNNIYII