Gene 81146.m00064 (T.vaginalis)

81146.m00064

Species: T.vaginalis
Alias: TvagK0141, 81146.m00064
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
81146.m00064.AA Protein None 330 None Fasta, JSON
81146.m00064.kin_dom Protein Kinase Domain None 244 None Fasta, JSON

Protein domain

Protein domains of 81146.m00064.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 81146.m00064.AA S_TKc 14-257 27 1.7e-77 264.69 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-231/231
Sequence Identity: 27% (72 aa)

IICKDVIAKGGYGTILLVYSTQYKAEFALKKVPLKGFNQLEIETLTSLDHRNIISLYKCYRYNSFVYLLMEYCVS---DLDSFIRKNKN------IDPQT
    ..| ||..|.  ... .  . ..|.|...     . ||. | . .| ||. || ...  ...|. ||||     || ..|.|..       ... .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H

VRKYCFEILQALKACHDKKIAHGDIKPSNFLIDSYGRLKICDFGLSSLIRESFLASRYTGTPLFMSPELIKKEEYNAMKSDIWAAGVTFYFLATRKYPFR
.|.|. .|..||. ||...| | |.||.| |.|.  ..|||||||. ..      . . ||| .|.||..    |.  |.|.|. |...| ..... ||.
ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP

SETIDSLKEVILTGQYKSRNISDLELQDVISMCLKVDPNDRASIDELLS-------MPYF
  ... . ..|.          . |. | |. ||..||..| .. |.|        .|.|
--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 81146.m00064.AA CAMK 19-257 18 3.2e-70 225.26 In-house 1-425 (425) Show / Hide 
Range on Protein: 19-257
Range on HMM: 1-425/425
Sequence Identity: 18% (79 aa)

VIAKGGYGTILLVYSTQYK------------AEFALKKVPLKGFN---------------------------------QLEIETLTS-------LDHRNI
.. .|..|.  |.. .. .             ..| | .. |                                    . ||| . .       |||.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

ISLYKCYRY-------------------NSFVYLLM---EYCVS-----DLDSFIRKNKN---------------IDPQTVRKYCFEILQALKACHDKKI
|.||  |                     ....|. |   |||       || ..|.....               .. . .|.|   |..|.. ||...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

AHGDIKPSNFLIDSY-----------------GRLKICDFGLSSLIRESF------------------------LASRYTGTPLFMS-PELIKK------
.| |.|| | |.|.                  . .||.|||..  ....                         . . . ||| .|. ||....      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------EEYNAMKSDIWAAGVTFYFLATRKYPFRSE-------------TIDSLKEVILTGQYK-SRN----------------ISDL-------ELQD
       ..|   |.|.|..||  |.. . ..||...             ..  |.| |..|.|                     |||        | .|
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

VISMCLKVDPNDRASIDELLSMPYF
 |. .|.|||..|..|.. |. | .
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 81146.m00064.AA Pkinase 14-257 24 6.9e-65 226.68 Pfam 1-293 (293) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-293/293
Sequence Identity: 24% (71 aa)

IICKDVIAKGGYGTILLVYSTQYKAEFALKKVPLKGFNQ-------L--EIETLTSLDHRNIISLYKCYRYNSFVYLLMEYCVS-----DLDSFIR--KN
. .. .| .|..|.  . .   .  ..|.|...... .        .  ||. . .|.| ||. || ...... .|. ||||       || ..|.  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KNI--DPQTVRKYCFEILQALKACHDKKIAHGDIKPSNFLIDSYGRL----KICDFGLSSL--IRESFLASRYTGTPLFMSPELIKKEEYNAMKSDIWAA
...  .......|. .||..|. ||...| | |.||.|.|||. | .    |||||||. .  .  .  .. ..||| .|.||.|.. .|   |.|.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVTFYFLATRKYPFRSE------TIDSLKEVILTGQYKSRNISD---------------------LELQDVISMCLKVDPNDRASIDELLSMPYF
|...| ..... ||...      . . . . |. .....    .                      |..|.|. ||..||..| .....|  |.|
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 81146.m00064.AA CAMKL 13-257 26 7.3e-62 196.15 In-house 1-297 (297) Show / Hide 
Range on Protein: 13-257
Range on HMM: 1-297/297
Sequence Identity: 26% (80 aa)

GIICKDVIAKGGYGTILLVYSTQY-KAEFALKKVPLKGFN--------------------QLEIETLTSLD---HRNIISLYKCYRYNSF------VYLL
 .|.| .. ||..|.  |   ... . . | | .  |. .                    . ||. . .|.   | |||.|| ..   ..      .|| 
YRIGK-TLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

MEYCVSD---LDSFIRKNKN----IDPQTVRKYCFEILQALKACHDKKIAHGDIKPSNFLIDSYG--RLKICDFGLSSLIR------ESFLASRYTGTPL
|||| .    |  .|.|...    ...   |.|   |. |.. ||...|.| |||| | |.|. |   .||.|||.| ..|      . .|  .  |.| 
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFC-GSPP

FMSPELIKK--EEYNAMKSDIWAAGVTFYFLATRKYPFRSET--------IDSLKEVILTGQYKSRNISDL-ELQDVISMCLKVDPNDRASIDELLSMPY
.|.||....  ..|.. | |||..||. |.. . ..||. .|        |  |.. | .| |. .  ... ...| |.  |.|.|..|..|..... | 
YMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNHPW

F
.
M
Kinase 81146.m00064.AA ULK 14-257 23 8.4e-59 201.66 In-house 1-329 (329) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-329/329
Sequence Identity: 23% (78 aa)

IICKDVIAKGGYGTILLVYSTQYK----AEFALKKVPLKGFNQ---------------LEIETLTSLD--------HRNIISLYKCYRYN--SFVYLLME
.. .... || .|.    .  . |      .| |..... .||                ||...  |.        | ||. ||....      .|. ||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCVS-DLDSFIRKNKN----------IDPQTVRKYCFEILQALKACHDKKIAHGDIKPSNFLIDSY------------GRLKICDFGLSSLIRES----F
||   ||...| |||.          .  | .....  ||...|. |...| | ||||.| ||.              |.|||.|||..  . ..    .
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

LASRYT------GTPLFMSPELIK----KEEYNAMKSDIWAAGVTFYFLATRKYPFRSETIDSLK-----EV----------ILTGQYKSR-----NISD
..  ..      ||||.|.|....    ...|.  |.|||  |. || . . |.||..  . ...     .           | . . . .     ..  
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

LELQDVISMCLKVDPNDRASIDELLSMPYF
 |..| |. .|..|..|| |..||...| |
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 81146.m00064.AA ULK 14-257 23 1.2e-58 201.2 In-house 1-324 (324) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-324/324
Sequence Identity: 23% (77 aa)

IICKDVIAKGGYG-TILLVYSTQY---KAEFALKKVPLKGFNQ---------------LEIETLTSLD---HRN--IISLYKCYRYN--SFVYLLMEYCV
.. .... || .| .    .  .    .  .| |....|..|.                ||...  |.   | |  |. ||....     ..|. |||| 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

S-DLDSFIRKN---------KNIDPQTVRKYCFEILQALKACHDKKIAHGDIKPSNFLIDSY------------GRLKICDFGLSSLIRESFLASRYT--
  ||...| ||         |..  | .....  |....|. |...| | ||||.| ||               |.|||.|||..  . .  ..   .  
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

--------GTPLFMSPELIK----KEEYNAMKSDIWAAGVTFYFLATRKYPFRSETIDSLKE--------------VILTGQYKSR-----NISDLELQD
        ||||.|.|....    ...|.  |.|||  |. || . . ||||.|  . ....               | . . . .     ..   |..|
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

VISMCLKVDPNDRASIDELLSMPYF
 |. .|..|..|| |..|....| |
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 81146.m00064.AA AGC 14-257 16 1e-57 146.75 In-house 1-395 (395) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-395/395
Sequence Identity: 16% (67 aa)

IICKDVIAKGGYGTILLVYST------QYKAEFALKKVP-----------LKGFNQLE------------IETLTSLD----------HRNIIS-LYKCY
   . || ||..|.  ||         . .  .|.|..                .. |             . |. ..          | .|.. |. ..
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

RYNSF--VYLLMEYCV---------SDLDSFIRKNK-----NIDPQTVRKYCFE-------ILQALKACHD-KKIAHGD-IKPSNFLIDSYGRLKICDFG
  ..   .|..|||.           ....|... .       | ...| |. |       |. ||   |. ..| | | .|| | |.|. | .|..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSSLIRES---------------------------------------------------FLASRYTG--TPLFMSPELIKKEEYNAMKSDIWA--AGVTF
|.  .. .                                                   ....   |  || .|.|| .          |.|.   |. .
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGCLM

YFLATRKYPFRSETID----------SLKEVIL--------TGQYKS---------RNISDLELQDVISMCLKVDPNDRAS----------IDELLSMPY
| . | . ||.... .           . . |.          .. .         |..|. |..| |...|..||..|            ..|. . |.
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSP-EAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPW

F
|
F
Kinase 81146.m00064.AA Ciliate-E2 14-257 20 8.8e-57 193.44 In-house 1-365 (365) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-365/365
Sequence Identity: 20% (77 aa)

IICKDVIAKGGYGTILLV--YSTQYKA---------------------EFALKKVPLKGFNQLEIETLTS------------------LDHRNIISLYKC
..   .| .|..|.. ..  ...|..                      ..|.| .  .. .|.. |                      |.| ||| .| |
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YR--YNSFVYLLMEYCVS-DLDSFIRKN-----------KNIDPQTVRKYCFEILQ---------------ALKACHDKK-IAHGDIKPSNFLIDSYGRL
.    .. .|| ||||   || ..|..|           |... . ....  .|||               ||. .| |. | | ||||.| |.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KICDFGLSSLIRES--------------------------------FLASRYTGTPLFMSPELIKKEEYNA--------MKSDIWAAGVTFYFLATRKYP
||.|||||  . ..                                ... .. ||| .|.|| .....|.          |.|||..||..|.. . |.|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FRSETIDSLKEVILTGQYK------------------SRNISDLELQDVISM----CLKVDPNDRAS-IDELLSMPYF
|         . |. ....                  | .  ..| .| |.     .|..||. | . ....|  |.|
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 81146.m00064.AA MARK 17-257 31 3.5e-56 182.23 In-house 4-262 (262) Show / Hide 
Range on Protein: 17-257
Range on HMM: 4-262/262
Sequence Identity: 31% (82 aa)

KDVIAKGGYGTILLVYSTQYKAEFALKKVP---LKGFNQ-----LEIETLTSLDHRNIISLYKCYR--YNSF-VYLLMEYCVS-DLDSFIRKN--KNIDP
. .| .|.|..  |. .. .. ..|.| ..   |  ...      ||| . .||| |||.|..      ..  .|| |||. . .| ..|..     .  
LKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGRLHE

QTVRKYCFEILQALKACHDKKIAHGDIKPSNFLIDSYG--RLKICDFGLSSLIRESFLASRYTGTPLFMSPELIKKEEYNAMKSDIWAAGVTFYFLATRK
   |...  |. |.. ||.| |.| |||| | |||. |    ||.|||.|  | .  . ..  ||| .|.||...|..|.. | |||. ||  ||. . .
EEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGY

YPFRSET--IDSLKEVILTGQYK-SRNISDLELQDVISMCLKVDPNDRASIDELLSMPYF
.||.  |  .  |.. ||.|.|.   ..|. |... |.  |.|.|..|..|.|... | .
FPFDGDTQDYKELYKKILRGKYDIPCHVSK-ECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 81146.m00064.AA Ciliate-E2-Unclassified 14-257 20 8e-51 174.52 In-house 1-352 (352) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-352/352
Sequence Identity: 20% (74 aa)

IICKDVIAKGGYGTILLVYSTQYKAEF-------ALKKVPLKGFNQ-----LEIETLTS-------------------LDHRNIISLYKCYRYNSFVYLL
 .   .| .||.|.. ...  . | ..         ...  |  ..     .|.... .                   ..| .|. .. | .    .|. 
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEYCVS-DLDSFIRKNKN-----------------IDPQTVR-----KYCFEILQALKACHDKK-IAHGDIKPSNFLIDSYG---RLKICDFGLSSLIRE
||||   ||  .|.|.|.                 .. | ..     .|. .|||.|. .| |. | | ||||.| |.|. |   ..||.|||.|. . .
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

S------------FLASRYT----GTPLFM----SPELIKKEEYNAM---KSDIWAAGVTFYFLATRKYPFRSETIDS----------------LKEVIL
.            .. .  .    ||| .|    .||......|. .   |.|||. || .|.. . .||| ... ..                |.. |.
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

TGQYKSRN--------ISDLELQDVIS----MCLKVDPNDRASIDELLSMPYF
 .... ..        ... | .| |.     .||..|| | .....|  |.|
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 81146.m00064.AA STE 14-257 19 1.2e-47 164.59 In-house 1-359 (359) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-359/359
Sequence Identity: 19% (73 aa)

IICKDVIAKGGYGTILLVYST------QYKAE---------FALKKVPLKGFN----------------------QLEIETLTSLD--HRNIISLYKCYR
  . ..| ||..||  . .        . . .         .| |...|.  |                      . ||...  ..  | ||.  | || 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

YN-------SFVYLLMEYCV-SDLDSFIRKNKNIDP--------------QTVRKYCFEILQA-LKACHDKKIAHGDIKPSNFLIDSYGRLKICDFGLSS
..       . ... |||.    ||..|.... .                . ....|..||.. |.  |...| | ||||.| |.      |.||||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

LIRE-----------------SFLASRYTGTPLFMSPELIKKEE------YNAMKSDIWAAGVTFYFLATRKYPFRSETIDSLKEVILTGQ---------
 . .                 .      .||| .|.|| |....      |.. |.|||  | |   .|| |.|.  ..  .    |....         
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDT-KCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

----YKSRNISD----------------------LELQDVISMCLKVDPNDRASIDELLS--MPYF
     ..  . |                       |..| |. ||. |||.|.. ..||.   | .
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 81146.m00064.AA NEK 22-257 28 6.5e-44 152.21 In-house 9-286 (286) Show / Hide 
Range on Protein: 22-257
Range on HMM: 9-286/286
Sequence Identity: 28% (79 aa)

KGGYGTILLVYSTQYKAE-----FALKKVPLKGFNQ--------LEIETLTSLDHRNIISLYKCYRYNS--FVYLLMEYCVS--DLDSF---IRKNK---
.| .|.  .| ... . .     ...||. ... ..         |.  | .|.| ||.. | ..  .   . .  ||||    ||. .   | |.|   
QGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKSIKKQKQKG

-NIDPQTVRKYCFEILQALKACHDK-----KIAHGDIKPSNFLIDSYGR----LKICDFGLSSLIRES--FLASRYTGTPLFMSPELIKKEEYNAMKSDI
 ...  .. .... .. ||| .||.     || | ||||.|  ... ..    .|| |||.| .   .  .. . ..||| .||||... . ||  ||||
KYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNKPYN-NKSDI

WAAGVTFYFLATR--KYPFRSE--TIDSLKEVILTG-QYKSRNISDL-----ELQDVISMCLKVDPNDRASIDELLSMPYF
|. |.  | ..|   | ||...   . ||   |  | ||.   |..      .||..||..|..|| .| |....|.||. 
WSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYP--PIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase 81146.m00064.AA TyrKc 14-257 20 4.4e-13 -11.14 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-280/280
Sequence Identity: 20% (59 aa)

IICKDVIAKGGYGTILL-VYSTQYKAEFALKKVP---LKGFNQLEIETLTSL--DHRNIISLYKCYRYN-------SFVYLLMEYCVS-DLDSFIRKNKN
|  ....  | .|.. . ...     . | |..    .. |   |.. ...|  .| ||. || . .           ....|||.   ||....||...
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDAREDF-MREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

-IDPQTVRKYCFEILQALKACHDKKIAHGDIKPSNFLIDSYGRLKICDFGLSSLIRES--------FLASRY--TGT---PLF-MSPELIKKEEYNAMKS
 . ...  ..|. | .     |.|.. | |.   | |... .. ||.|||||  | .            ..    |    |.  |.|| |.. ...  ||
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-TKS

DIWAAGVTFYFLATRKYPFRSE------TIDSLKEVILTGQYKSRNIS---------DLELQDVISMCLKVDPNDRASIDELLSMPYF
|.|. ||. . . |.  .  ..      . . . | . .| .  .  .           |. .....| . ||.|| .  |.    .|
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 81146.m00064.AA Pkinase_Tyr 54-112 25 0.000231 15.4 Pfam 53-120 (270) Show / Hide 
Range on Protein: 54-112
Range on HMM: 53-120/270
Sequence Identity: 25% (17 aa)

EIETLTSL-DHRNIISLYKCYR-YNSF--VYLLMEYCVS-DLDSFIRK----NKNIDPQTVRKYCFEI
|......| .| ||..|| .         .|. |||.   ||... ||    ........  ..|..|
EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQI
Kinase 81146.m00064.AA Pkinase_Tyr 135-153 47 1.635664 2.36 Pfam 143-161 (270) Show / Hide 
Range on Protein: 135-153
Range on HMM: 143-161/270
Sequence Identity: 47% (9 aa)

LIDSYGRLKICDFGLSSLI
|... .  |||||||. .|
LVTENNVVKICDFGLARDI