Gene 81529.m00386 (T.vaginalis)

81529.m00386

Species: T.vaginalis
Alias: TvagK0904, 81529.m00386
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
81529.m00386.AA Protein None 385 None Fasta, JSON
81529.m00386.kin_dom Protein Kinase Domain None 209 None Fasta, JSON

Protein domain

Protein domains of 81529.m00386.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 81529.m00386.AA Ciliate-E2 116-268 24 5.9e-40 134.82 In-house 168-365 (365) Show / Hide 
Range on Protein: 116-268
Range on HMM: 168-365/365
Sequence Identity: 24% (54 aa)

SVIDAVKYLHENN-IIHNDIRPENVIYIDRGFKLSNFMHAQYVDFD-------------------TVTKS--------------YGTLNYQAPEFYIDR-
..|.|..|||..| ||| || |||...     |.. |  ....| |                   ..| .              .||..|.||| .    
CIILALEYLHSKNNIIHRDIKPENILF----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKK

------QTQYPKAADIWAMGLTLLFILTGKDPFIIPDDLSLKEKKDFLTQQIVES-KIKIP------------------EYLHPAAKNLISR----MLES
      |..| ...|||..| .| . |.|| ||                ||. .  ||..|                  ... . .|.||..    ||. 
YDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF----------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQK

NPTKRIT-VNELDKDPWI
.| ||||  ... . ||.
DPEKRITGWEQILNHPWF
Kinase 81529.m00386.AA CAMKL 60-268 25 1.4e-38 120.62 In-house 63-297 (297) Show / Hide 
Range on Protein: 60-268
Range on HMM: 63-297/297
Sequence Identity: 25% (60 aa)

IEILGSLS---HPCIHSLANYKLDGEI------AYLFFEKSQGN---AFTLIQEKGQ----LPEPEAGLKFLSVIDAVKYLHENNIIHNDIRPENVIYID
|.|. .|.   || | .|     . |        ||. |  .|     |  |...|     .||.||   |  ...||.|.|...|.| || |||.   .
IQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDE

RG--------FKLSNFMHAQ-YVDFDTVTKSYGTLNYQAPEFYID-RQTQYPKAADIWAMGLTLLFILTGKDPFIIPDDL--SLKEKKDFLTQQIVESKI
.|        | .||..  .   . .. . . |...|.||| . .  .  . ...|||..| .| ....|. ||  ...     . .  .. ....  . 
NGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YY

K-IPEYLHPAAKNLISRMLESNPTKRITVNELDKDPWI
  |. ..   ...||..||. ||.||.|. .. ..|| 
PPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 81529.m00386.AA CAMK 60-268 20 1.9e-37 117.74 In-house 82-425 (425) Show / Hide 
Range on Protein: 60-268
Range on HMM: 82-425/425
Sequence Identity: 20% (69 aa)

IEILGSLS-------HPCIHSLANYKLDGEI-------------------AYLFF---EKSQGN----A-FTLIQEKGQ---------------LPEPEA
|||. .|.       ||.| .|  .  |..                     |...   |  .|       |  |.|.|.               ..| ||
IEIMKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREA

GLKFLSVIDAVKYLHENNIIHNDIRPENVIYIDRG------------------FKLSNFMHAQYVDF-------------------------DTVTKSYG
   |  ...||.|.|..||.| |. |||. . |..                   |.. |  |...|                          .  . . |
RRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCG

TLNYQA-PEFYIDR------------QTQYPKAADIWAMGLTLLFILTGKDPFIIPDDLSLKE------KKDFLTQQIVESKIK-IPEY-----------
|. | | ||                 .. |....|.|..|  | . |.|. ||  ..| .  |          | ..| . |   .|.|           
TPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPE

------------LHPAAKNLISRMLESNPTKRITVNELDKDPWI
            . . .|.||..||. .|.||.|. .  ..||.
WWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 81529.m00386.AA Ciliate-E2-Unclassified 114-268 24 1.5e-33 113.74 In-house 149-352 (352) Show / Hide 
Range on Protein: 114-268
Range on HMM: 149-352/352
Sequence Identity: 24% (51 aa)

FLSVIDAVKYLHENN-IIHNDIRPENVIYIDRG----FKLSNFMHAQYVD-----------------FDTVTKSYGTLNYQ----APEFYIDRQTQYP--
|  .... .|||..| ||| || |||... . |     |.. |  . . .                 ..  .   ||.||.    ||| ....| ..   
FAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPE-VLQGQNYDHSK

-KAADIWAMGLTLLFILTGKDPFIIPDDLSLK--------------EKKDFLTQQIVESKIK---IPEYLHPAAKNLIS----RMLESNPTKRITVNELD
 ...|||..|  | ..|.|. ||  ... . .               ..... ..|  .| .   ||  ..| ||..|.    .||. || |||| ... 
AYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQIL

KDPWI
. ||.
NHPWF
Kinase 81529.m00386.AA MSK 96-268 29 2.8e-27 89.24 In-house 89-277 (277) Show / Hide 
Range on Protein: 96-268
Range on HMM: 89-277/277
Sequence Identity: 29% (55 aa)

FTLIQEKGQLPEPEAGLKFLSVIDAVKYLHENNIIHNDIRPENVIYIDR----GFKLSNFMHAQYVDFD--TVTKS-YGTLNYQAPEFYID---RQTQYP
|| |  ..   | |.   ..... ||...|.  ||| |. |||. . |.      ||. |  | .   |    .||  .|| | |||   .    .. | 
FTHIRKREHFDESECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNGHVKLIDFGFARLFPQDEEWRMKSPCFTLHYMAPEMLRRGYAQDGGYD

KAADIWAMGLTLLFILTGKDPFI--IPDDLSLKEKKDFLTQQIVESKIKIP----EYLHPAAKNLISRMLESNPTKRITVNELDKDPWI
.| |.| .| .|   |||. ||    .|     .    . . | ...  .|    .   |.||.||...|. .| || ..|.|... |.
EACDWWSLGVILYTMLTGQVPFQQNEDDRQHSCNSHHEIMKRICKGEFSFPGMAWQNMSPDAKDLIQWLLTKDPKKRLGMNDLRAHEWK
Kinase 81529.m00386.AA Pkinase 60-268 19 4.4e-26 93.29 Pfam 51-293 (293) Show / Hide 
Range on Protein: 60-268
Range on HMM: 51-293/293
Sequence Identity: 19% (51 aa)

IEILGSLSHPCIHSLANYKLDGEIAYLFFEKSQG-----NAFTLIQ--EKGQL--PEPEAGLKFLSVIDAVKYLHENNIIHNDIRPENVIYIDRGFK---
|.|. .|.||.|  |  .  |.   |. .|  .|       |..|.  ..| .  .| |.   .. .. ...|.|...||| |. |||. . ..|     
IQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDAC

-------LSNFM-HAQYVDFDTVTKSYGTLNYQAPEFYIDRQTQYPKAADIWAMGLTLLFILTGKDPFIIPDDLSLKEK-------KDFLTQQIVESKIK
       |. .. .  .. ..|..   ||..| |||     .. |....|.|..|..|   |.|.        .  ...       .... ..| . ...
VKICDFGLAKQFDY-NNS-MTTFC---GTPWYMAPEVIR-GGQYYGPKVDMWSCGCILYEMLCGR--------PPFPGHCWHDNHDQMQMICRIMGPPLH

IPEYLH---------------------PAAKNLISRMLESNPTKRITVNELDKDPWI
 ...                       ...| .|...|. .|.||.|  .. ..||.
FDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 81529.m00386.AA CAMKK-Unclassified 114-268 20 6.3e-26 81.19 In-house 184-392 (392) Show / Hide 
Range on Protein: 114-268
Range on HMM: 184-392/392
Sequence Identity: 20% (44 aa)

FLSVIDAVKYLHENN---------------------IIHNDIRPENVIYIDRGF------KLSNFMHAQYVD--FDT-VTKSYGTLNYQAPEFYIDR-QT
|. .. ...|.| .|                     ||| || |.|    . .       |.. |  .. .    .. .    ||. ..||||  .  ..
FRQCCKGLQYMHNFNQACSYIIIYINEFDKIDHFQDIIHRDIKPQNILIDHEDNDKGEHFKIADFGISVIMEHEQQKKLKNNAGTYCFMAPEFWSKENFK

QYPKA-------------------------ADIWAMGLTLLFILTGKDPFIIPDDLSLKEKKDFLTQQIVESKIKIP----EYLHPAAKNLISRMLESNP
. ...                         ||||. | |.  . ... ||   ..  |..      |.|  ..|. |      . . .|.|| .|.. ||
YDYNDYSFLPGTFNPLRKTYRIERICFYKKADIWSLGVTFYCMVYHSLPFWHKNLQELFH------QMICQKEINFPPQYHPHCSHEFKDLIQKMCDKNP

TKRITVNELDKDPWI
.||||.  . ..||.
KKRITIDQMLVHPWF
Kinase 81529.m00386.AA CAMKK 114-268 25 1.3e-24 74.63 In-house 182-396 (396) Show / Hide 
Range on Protein: 114-268
Range on HMM: 182-396/396
Sequence Identity: 25% (54 aa)

FLSVIDAVKYLH-ENN-------------------IIHNDIRPENVIYIDRG----FKLSNFMHAQYVDFDTVTKSY-------------GTLNYQAPEF
|. .| ...||| ...                   ||| || |.|    . |    .|.. |  .. .. .. |.|              ||  ..|||.
FRDCIKGLEYLHNYQKACSYIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFGVSHIFEGQDQTLSNCESCFQRELNKTAGTPAFMAPEL

YID-RQTQ-------------YPKAADIWAMGLTLLFILTGKDPFIIPDDLSLKEKKDFLTQQIVESKIK---------IPEYLHPAAKNLISRMLESNP
  .  |..               |||||||.| ||  ...|| ||.  ... |..  .   .. ......          .. . . .|.|| |||| ||
CSKENQKENYNGYKYRFRFIYCGKAADIWALGVTLYCFVFGKCPFWHNNLMQLHHNYMKIKNDPIKFPENKEMLNNVSIYCPEISEDLKDLIKRMLEKNP

TKRITVNELDKDPWI
|||||. .. ..||.
TKRITIPQIKVHPWV
Kinase 81529.m00386.AA STE 100-268 20 4.5e-23 78.39 In-house 144-359 (359) Show / Hide 
Range on Protein: 100-268
Range on HMM: 144-359/359
Sequence Identity: 20% (45 aa)

QEKGQLPEPEAGLKFLSVIDA-VKYLHENNIIHNDIRPENVIYIDRGFKLSNFMHAQYVDFD------------------TVTKSYGTLNYQAPEFYIDR
. .. .||.. .    ... .  .|||...||| || | |.       ||..| ..  .. .                    .   ||  . |||    .
H-QHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQN

Q----TQYPKAADIWAMGLTLLFILTGKDPF---IIPDDLSLKEKK-------DFLTQQIVESKIKIPEYLH-------------------PAAKNLISR
.     .|   .|||  |.|..  .||| |.     .  . .. ..       ..| ... .   ..|. |.                   |  |. |..
GQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL-CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINK

MLESNPTKRITVNELDK--DPWI
 |. .| || |...| |   |.|
CLQKDPNKRPTASQLLKSEHPFI
Kinase 81529.m00386.AA RSK 96-268 30 2.5e-22 78.65 In-house 89-278 (278) Show / Hide 
Range on Protein: 96-268
Range on HMM: 89-278/278
Sequence Identity: 30% (59 aa)

FTLIQEKGQ---LPEPEAGLKFLSVIDAVKYLHENNIIHNDIRPENVIYID----RGFKLSNFMHAQY--VDFDTVTKSY-GTLNYQAPEFYID---RQT
|| .|....   . | ||   .  .. ||..||.  ||| |. |||..| |    .  ||. |  . .   |.   |... .|..| |||  .    .| 
FTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEM-LKRANQQG

QYPKAADIWAMGLTLLFILTGKDPFIIPDDLSLKEKKDFLTQQIVESK--IKIP--EYLHPAAKNLISRMLESNPTKRIT-----VNELDKDPWI
 . ||.|.|  |  .   |||. ||  |.|    . .. . ..| . |   ..|  .|| ..||.||..||. .| ||..     ..|. ..||.
GHDKACDWWSLGVLMYEMLTGCPPFQGPND----NNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
S_TKc 81529.m00386.AA S_TKc 21-268 24 5e-20 73.78 SMART 1-231 (231) Show / Hide 
Range on Protein: 21-268
Range on HMM: 1-231/231
Sequence Identity: 24% (67 aa)

YYIE-----------YEAKKVNGQSYTAMEVIISRLCNFDYPQFLKIRNMIEILGSLSHPCIHSLANYKLDGEIAYLFFEKSQG---NAFTLIQEKGQ--
| |            | ..... . . |. .|             .||. |.|| .  || |  |  .  | .  |...|   |   . |..|...|   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LPEPEAGLKFLSVIDAVKYLHENNIIHNDIRPENVIYIDRGFKLSNFMHAQYVDFDTVTKSYGTLNYQAPEFYIDRQTQYPK-AADIWAMGLTLLF
    .|| .|   .  ...|..|.|...||| |. |||.   .   |.. |  |  .     |   ||..| |||       .| | ..|.|. | .|  
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL-----TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCILYE

ILTGKDPFIIPDDLSLKEKKDFLTQQIVESKIKIPEYLHPAAKNLISRMLESNPTKRITVNELDK-------DPWI
 |.|. ||            . . ..|.           | ||..|...|. .|.||.|. |. .       .||.
MLCGYPPFP---------QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 81529.m00386.AA MARK 167-268 33 4.2e-15 45.99 In-house 167-262 (262) Show / Hide 
Range on Protein: 167-268
Range on HMM: 167-262/262
Sequence Identity: 33% (35 aa)

GTLNYQAPEFYIDRQTQYPKAADIWAMGLTLLFILTGKDPFIIPDDLS--LKEKKDFLTQQIVESKIKIPEYLHPAAKNLISRMLESNPTKRITVNELDK
||. | |||  . ..  . ...|||..|  | |...|. ||    . .  .||    | ..|.  | .|| .. . ..|||.|.|  || .|.|. |. |
GTPPYMAPEI-FLKKPYDGPKVDIWSLGVVLYFMVCGYFPFD---GDTQDYKE----LYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMK

DPWI
.||.
HPWM
Kinase 81529.m00386.AA MARK 96-139 41 8.1e-14 41.72 In-house 90-135 (262) Show / Hide 
Range on Protein: 96-139
Range on HMM: 90-135/262
Sequence Identity: 41% (19 aa)

FTLIQEK--GQLPEPEAGLKFLSVIDAVKYLHENNIIHNDIRPENV
.  |...  | |.|.||   |  .. ||.|.|..||.| || |||.
YDYIKAHPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENI