Gene TVAG_116390 (T.vaginalis)
TVAG_116390
Species: T.vaginalis
Alias: TvagK1044, TVAG_116390
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| TVAG_116390.AA | Protein | None | 579 | None | Fasta, JSON |
| TVAG_116390.kin_dom | Protein Kinase Domain | None | 128 | None | Fasta, JSON |
Protein domains of TVAG_116390.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | TVAG_116390.AA | Ciliate-E2-Unclassified | 67-151 | 25 | 6.5e-07 | 20.05 | In-house | 77-191 (352) | Show / Hide |
Range on Protein: 67-151 Range on HMM: 77-191/352 Sequence Identity: 25% (29 aa) DHPNIPKVHSLYFAEEKEKAVLSASY-------QYIQA-----------AENNGNVHSLLESKAI--------YNIFKTIQYIHQNG-IHHCDLDIANIL .||.. .|. .| . |.. . | |||. .|. . . . | .|. . | . ..|.|... | | |. ||| NHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENIL FLDNG---DIAIIDF | .|| | |||| FDNNGKNYYIKIIDF |
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| Kinase | TVAG_116390.AA | NuaK | 120-151 | 40 | 9e-06 | 10.56 | In-house | 112-143 (252) | Show / Hide |
Range on Protein: 120-151 Range on HMM: 112-143/252 Sequence Identity: 40% (13 aa) IQYIHQNGIHHCDLDIANILFLDNGDIAIIDF . | |...| | || ||| .|... | || VHYCHKHRICHRDLKLENILLDQNCNAKIADF |
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| Kinase | TVAG_116390.AA | CMGC | 113-151 | 23 | 1e-05 | 13.81 | In-house | 180-248 (513) | Show / Hide |
Range on Protein: 113-151 Range on HMM: 180-248/513 Sequence Identity: 23% (16 aa) I------YNIFKTIQ--YIHQNG--IHHCDLDIANILFLDN--------------------GDIAIIDF . | |.. . |.|... | |.|| .|||. .| | . |.|| MIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDF |
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| Kinase | TVAG_116390.AA | Ciliate-C3 | 116-151 | 41 | 1e-05 | 16.87 | In-house | 105-140 (140) | Show / Hide |
Range on Protein: 116-151 Range on HMM: 105-140/140 Sequence Identity: 41% (15 aa) IFKTIQYIHQNGIHHCDLDIANILFLDNGDIAIIDF | . |.|.| | | |. ..||| ...| |||| ILQAIDYLHEHNIVHGDIKFSNILINSKDEIKIIDF |
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| Kinase | TVAG_116390.AA | CDK10 | 116-151 | 36 | 1.2e-05 | 15.32 | In-house | 109-144 (285) | Show / Hide |
Range on Protein: 116-151 Range on HMM: 109-144/285 Sequence Identity: 36% (13 aa) IFKTIQYIHQNGIHHCDLDIANILFLDNGDIAIIDF . . ..|.|.| . | || ..|.|. |.| | . || MLRGLKYLHDNFMIHRDLKVSNLLMTDKGCIKVADF |
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| Kinase | TVAG_116390.AA | Kin1 | 116-151 | 50 | 1.5e-05 | 16.78 | In-house | 134-169 (279) | Show / Hide |
Range on Protein: 116-151 Range on HMM: 134-169/279 Sequence Identity: 50% (18 aa) IFKTIQYIHQNGIHHCDLDIANILFLDNGDIAIIDF | .||.| | | | || | ||. | ..| |||| IASALQYLHANNIVHRDLKIENIMISDSSEIKIIDF |
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| S_TKc | TVAG_116390.AA | S_TKc | 15-205 | 17 | 4.8e-05 | -102.99 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 15-205 Range on HMM: 1-231/231 Sequence Identity: 17% (44 aa) SNFKQFYGFGTGGNCYIRVNER------LKQIFKSYKLDKQNIDSVKHILRDTCIVAFDHPNIPKVHSLYFAEEK-----EKAVL--SASYQYIQAAENN . . | |. | .| .. . .|.| .||.| | .|||| | . . .. | . ..||. . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------EHIRREIQILKKHHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH GN---VHSLLESKAIYNIFKTIQYIHQNGIHHCDLDIANILFLDNGDIAIIDFD--------------------RYNQ-----------------GEI-- |. . . .| |.. ..|.|..|| |.|| .|||. . | |.|| |. |. GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQLTTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCGYPPF RHADEIFVNSILMEYSDEFALLIFSIIY-SGK--LSCSEDLR----NEIHDFV . .. . |. |.|. .| . . ... | |. .| .. P-QMQMMFKKIG---SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | TVAG_116390.AA | RSK | 114-151 | 40 | 7.1e-05 | 13.6 | In-house | 108-149 (271) | Show / Hide |
Range on Protein: 114-151 Range on HMM: 108-149/271 Sequence Identity: 40% (17 aa) YNIFKTIQYIHQNGIHHCDLDIANILFLDN----GDIAIIDF ..|... .| |. || | || .|||. | | | | || AEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDF |
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| Kinase | TVAG_116390.AA | SLK | 114-151 | 31 | 0.000251 | 10.37 | In-house | 104-141 (259) | Show / Hide |
Range on Protein: 114-151 Range on HMM: 104-141/259 Sequence Identity: 31% (12 aa) YNIFKTIQYIHQNGIHHCDLDIANILFLDNGDIAIIDF . . .....|.| . | || |||. .||. . || KHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADF |
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| Kinase | TVAG_116390.AA | KHS | 115-151 | 37 | 0.000294 | 10.08 | In-house | 104-140 (258) | Show / Hide |
Range on Protein: 115-151 Range on HMM: 104-140/258 Sequence Identity: 37% (14 aa) NIFKTIQYIHQNGIHHCDLDIANILFLDNGDIAIIDF .. . ..|.|..| | |. |||| |.||. . || ETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADF |
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| Kinase | TVAG_116390.AA | Ciliate-B3 | 108-172 | 22 | 0.000496 | 11.39 | In-house | 1-69 (69) | Show / Hide |
Range on Protein: 108-172 Range on HMM: 1-69/69 Sequence Identity: 22% (16 aa) LESKAIYNIFKTIQYIHQNGIHHCDLDIANILFLDNGDI-----AIIDFDRYNQGEIRHADEIFVNSILM . | . ..|. .|. | |||. . ||| ... | |||| .. . . | .. FALKHFHQVVEKIKILHEKNICHCDIKVDNIL-VNQQDKENYKVIIIDFGHCQRKCQNCKSEMICGTLTY |
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| Kinase | TVAG_116390.AA | Pkinase | 111-151 | 40 | 0.000765 | 14.67 | Pfam | 112-156 (293) | Show / Hide |
Range on Protein: 111-151 Range on HMM: 112-156/293 Sequence Identity: 40% (18 aa) KAIYNIFKTIQYIHQNGIHHCDLDIANILFLDNGDI----AIIDF . .| |.. ..|.|..|| |.|| .|||. .||.| |.|| FYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDF |
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