Gene TVAG_079450 (T.vaginalis)

TVAG_079450

Species: T.vaginalis
Alias: TVAG_079450, TvagK1040
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
TVAG_079450.AA Protein None 365 None Fasta, JSON
TVAG_079450.kin_dom Protein Kinase Domain None 248 None Fasta, JSON

Protein domain

Protein domains of TVAG_079450.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase TVAG_079450.AA Aur 186-255 26 1.3e-12 29.08 In-house 179-250 (257) Show / Hide 
Range on Protein: 186-255
Range on HMM: 179-250/257
Sequence Identity: 26% (19 aa)

DYKADNWSLGIILAYFLTGEIPFNT-KNVFTTLQQIN-TGTLQYAGEVSPEYDTIIKRLVKVNPTERAELSD
|.| | |.||...  ...|  ||   .| ..|...|   . .|.   .|.|    |... ...| .|  | .
DHKVDIWCLGVLCYELCHGCPPFESNENHDETYDRIKNKVDIQFPSHISKEAKDLISKILQHDPKQRMTLDQ
Kinase TVAG_079450.AA AGC 173-250 22 5.1e-12 25.86 In-house 273-373 (395) Show / Hide 
Range on Protein: 173-250
Range on HMM: 273-373/395
Sequence Identity: 22% (24 aa)

FLAPEFIAPEYEPDYKADNWS--LGIILAYFLTGEIPFNTKN----------VFTTLQQIN------TGTLQYA----------GEVSPEYDTIIKRLVK
..||| .      .. .| ||  ||...  .|||  ||. .|           . . |.|       .  ...            ..|||   .||.| .
YMAPEIL-----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLC

VNPTER
..|..|
KDPEKR
Kinase TVAG_079450.AA MARK 187-255 33 1.8e-11 33.95 In-house 185-255 (262) Show / Hide 
Range on Protein: 187-255
Range on HMM: 185-255/262
Sequence Identity: 33% (24 aa)

YKADNWSLGIILAYFLTGEIPFN--TKNVFTTLQQINTGTLQYAGEVSPEYDTIIKRLVKVNPTERAELSD
.|.| ||||..| . ..|  ||   |..  .  ..|..|  ..   ||.|   .|.|| .||| ||. ...
PKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEE
Kinase TVAG_079450.AA CAMKL 187-255 25 4.7e-11 31.37 In-house 215-290 (297) Show / Hide 
Range on Protein: 187-255
Range on HMM: 215-290/297
Sequence Identity: 25% (20 aa)

YKADNWSLGIILAYFLTGEIPFNTK--------NVFTTLQQINTGTLQYA--GEVSPEYDTIIKRLVKVNPTERAELSD
.|.| ||.|.||   ..|. ||.          |. . . .|..|  ..    .|| .   .|... .|||..|. . .
PKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQ
Kinase TVAG_079450.AA Ciliate-E2 173-250 25 5.9e-11 33.83 In-house 253-352 (365) Show / Hide 
Range on Protein: 173-250
Range on HMM: 253-352/365
Sequence Identity: 25% (27 aa)

FLAPEFIA-PEYE-------PDYKADNWSLGIILAYFLTGEIPFNTKNVFTTLQQINTGTLQYAGE------------------VSPEYDTIIKR----L
..||| .   .|.        |||.| ||||.|| ..|.|. ||        .|||  . ...  .                  .|.|   .||.    .
YMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRM

VKVNPTER
 ...| .|
LQKDPEKR
Kinase TVAG_079450.AA S_TKc 11-264 17 7.4e-11 -17.73 SMART 1-231 (231) Show / Hide 
Range on Protein: 11-264
Range on HMM: 1-231/231
Sequence Identity: 17% (47 aa)

YQYKRPLGRGHLGSSYVLQNNK-GSYVYCKEILKESIGNKEQVQKFKERIERIRSLNQKYILPYFAVLEYDNKLLLLRKYLNP--GNIIEEAPKIKA---
|.  |..|.|  |. |  ...| | .| .|.|           ....  |.  .. . ..|  .. | .  ..| .   |..   |.  .   | .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LGPNKIFAMWCALARTYHLLHQNHLAPNLIRATNLFFYNGSNIIITDLYLATNDVNVMVHNPSPLDYSFLAPEFIAPEYEPDY-KADNWSLGIILAY
   . .  .  . . ...    .|...     .   |... .  .| |.|  ||.   . ..  |      ..||| .      .. |.| ||.|.||. 
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-TTFCGTP-----WYMAPEVL----GYGKCKCDWWSCGCILYE

FLTGEIPFNTKNVFTTLQQINTGTLQYAGEVSPEYDTIIKRLVKVNPTERAELSDFIK-----MNDTLK
.|.|. ||   ........|           |||   .|... ...|..|    .  .     ...   
MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase TVAG_079450.AA MELK 11-262 18 1.6e-10 31.89 In-house 1-254 (254) Show / Hide 
Range on Protein: 11-262
Range on HMM: 1-254/254
Sequence Identity: 18% (49 aa)

YQYKRPLGRGHLG----SSYVLQNNKGSYVYCKEILKESIGNKEQVQKFKERIERIRSLNQKYILPYFAVLEYDNKLLLLRKYLNPGNIIEEAPKIKALG
|.    .| | ..    ....| |..   |  | . |. .|  . . . |  .. ...|  . |   . ..| ..|....  |   |.. .   . . | 
YEVHDEIGTGGFAKVKLACHILTNQM---VAIKIMDKNQLG--HDLPRVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLE

PNKIFAMWCALARTYHLLHQNHLAPNLIRATNLFFYNGSNIIITDLYL-ATNDVNVMVH--NPSPLDYSFLAPEFIAPEYEPDYKADNWSLGIILAYFLT
 .    ..  .      .|    |   ..  ||.| .  .. . |. | |    ..  |  .       . ||| |         || ||.||.|   . 
EEETRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMC

GEIPFNTKNVFTTLQQINTGTLQYAGEVSPEYDTIIKRLVKVNPTERAELSDFIKMNDT
| .||.  |.    ..|  |  .    .|||   .......|.|. | .. . .. .  
GFLPFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV
Kinase TVAG_079450.AA PLK1 11-262 20 1e-09 27.83 In-house 1-253 (253) Show / Hide 
Range on Protein: 11-262
Range on HMM: 1-253/253
Sequence Identity: 20% (51 aa)

YQYKRPLGRGHLGSSYVLQNNKGSYVYCKEILKESIGNKE-QVQKFKERIERIRSLNQKYILPYFAVLEYDNKLLLLRKYLNPGNIIEEAPKIKALGPNK
|.  | ||.|     | .....   |.   .   |.  |. | .|  . |.  |.|. . |  ..   | .. . ..    .   ..|   . ||.    
YEKGRFLGKGGFAHCYEIRDKDTKEVFAGKVVPKSLLIKQHQRDKMTQEIQIHRQLHHRHIVKFHHFFEDKQNVYIVLELCRRRSLMELHKRRKAITEPE

IFAMWCALARTYHLLHQNHLAPNLIRATNLFFYNGSNIIITDLYLATN-DVNVMVHNPSPLDYSFLAPEFIAPEYEPDYKADNWSLGIILAYFLTGEIPF
       ...  . ||.|..    ..  |||. .  .. | |  |||. . .            ..||| .. .    .  | ||.| |.   | |. ||
CRYYMYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHLQVKIGDFGLATKCEYDGERKKTLCGTPNYIAPEVLN-KKGHSFEVDIWSIGCIMYILLFGQPPF

NTKNVFTTLQQINTGTLQYAGEVSPEYDTIIKRLVKVNPTERAELSDFIKMNDT
 || .  | ..|     .   ..|.    .|..... .||.| . .  ....  
ETKCLKETYSRIKKNEYRIPSHISQPAAQLIRKMLDPDPTRRPTIEQVLNDEFF
Kinase TVAG_079450.AA Ciliate-E2-Unclassified 171-250 25 1e-09 29.9 In-house 226-340 (352) Show / Hide 
Range on Protein: 171-250
Range on HMM: 226-340/352
Sequence Identity: 25% (29 aa)

YSFL----APEFIAP-EYEPD--YKADNWSLGIILAYFLTGEIPFNTKNVFT----------------TLQQINTGTLQYAG--------EVSPEYDTII
....    ||| .   .|.    ||.| ||||.|| ..|.|. ||. .|                    .|.|. . .|.           .|||.  .|
PNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFI

K----RLVKVNPTER
.    .. |.|| .|
NDLLQKMLKKNPNKR
Kinase TVAG_079450.AA CAMKK 173-255 22 1.1e-09 26.45 In-house 276-389 (396) Show / Hide 
Range on Protein: 173-255
Range on HMM: 276-389/396
Sequence Identity: 22% (26 aa)

FLAPEFIAPEYEPD---------------YKADNWSLGIILAYFLTGEIPFNTKNVFTTLQ---QINTGTLQYAG-------------EVSPEYDTIIKR
|.|||..  | .                  .|| |.||. | .|..|..||. .| . ..    .|    ...               |.|.. . .|||
FMAPELCSKENQKENYNGYKYRFRFIYCGKAADIWALGVTLYCFVFGKCPFWHNNLMQLHHNYMKIKNDPIKFPENKEMLNNVSIYCPEISEDLKDLIKR

LVKVNPTERAELSD
. . |||.|  ...
MLEKNPTKRITIPQ
Kinase TVAG_079450.AA CAMK 172-251 18 4.4e-09 24.65 In-house 284-414 (425) Show / Hide 
Range on Protein: 172-251
Range on HMM: 284-414/425
Sequence Identity: 18% (24 aa)

SFLA-PEFIAP-------------EYEPDYKADNWSLGIILAYFLTGEIPFNTK-------------NVFTTLQQINTGTLQYAGE--------------
.. | || .               .   ..|.| ||.|.||   |.|. ||. .             |   ....| .|  ..  .              
EYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWW

----------VSPEYDTIIKRLVKVNPTERA
          ||.|    |... .|.|..|.
DDISDEFHHFVSQECKDLIRKMLQVDPEKRM
Kinase TVAG_079450.AA Pkinase 173-250 20 2.1e-05 20.22 Pfam 177-281 (293) Show / Hide 
Range on Protein: 173-250
Range on HMM: 177-281/293
Sequence Identity: 20% (22 aa)

FLAPEFIAPEYEPDYKADNWSLGIILAYFLTGEIPFNTK------NVFTTLQQINTGTLQYAGEVS---------------------PEYDTIIKRLVKV
..||| |    . ..|.| ||.|.||...|.|. ||  .      .    ...|  . | .  . .                     .|   .||.. ..
YMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCK

NPTER
.|..|
DPKKR
Kinase TVAG_079450.AA Ciliate-E2-Unclassified 11-97 13 0.020549 4.21 In-house 1-110 (352) Show / Hide 
Range on Protein: 11-97
Range on HMM: 1-110/352
Sequence Identity: 13% (15 aa)

YQYKRPLGRGHLGSSYVLQNNKGSYVYCKEILKESIGNKEQVQKFK-------ERIERI----------------RSLNQKYILPYFAVLEYDNKLLLLR
|   . .|.|  |. | .|..|  ..| ....| .. .| . ...|       ......                ....  .|. .| . . .... .  
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

KYLNPGNIIE
 |.. |. ..
EYCEGGDLWQ
Kinase TVAG_079450.AA Pkinase 11-85 20 1.905628 2.66 Pfam 1-77 (293) Show / Hide 
Range on Protein: 11-85
Range on HMM: 1-77/293
Sequence Identity: 20% (16 aa)

YQYKRPLGRGHLGSSYVLQNNKGSY-VYCKEILKESIGNKEQVQKFK--ERIERIRSLNQKYILPYFAVLEYDNKLLL
|. .|..|.|  |. |  .. . .  | .|.| |...  ........  | |.  ..|| ..|. .. . |..... .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSE-IQIMKRLNHPNIVRLYDWFEDKDHIYM