Gene 86278.m00098 (T.vaginalis)

86278.m00098

Species: T.vaginalis
Alias: 86278.m00098, TvagK0997
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
86278.m00098.AA Protein None 336 None Fasta, JSON
86278.m00098.kin_dom Protein Kinase Domain None 257 None Fasta, JSON

Protein domain

Protein domains of 86278.m00098.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 86278.m00098.AA MELK 1-248 22 2.4e-12 38.21 In-house 4-254 (254) Show / Hide 
Range on Protein: 1-248
Range on HMM: 4-254/254
Sequence Identity: 22% (56 aa)

MNDLSNGFLGKTFLLKHNESSGTFVCKMISKEFLGNSDMVKAFIDKIKHLQDLNLTFIVNYTDILETETTIYLIRPYFNSQTLSSFLQSPDKQHDVNIVA
 ...  | ..|  |  |         |.. |. || .|. .   . .  |..|    |     ..|||  |...  |     .  .. . |. .. .   
HDEIGTGGFAKVKLACHILTNQMVAIKIMDKNQLG-HDLPRVKTE-MDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEETRH

LWKTIARSIMILHNNNISSLPIKPSNILIFNEKFISLTDM---YEIKSNIRWS-LETIDRKHLLFIPPEFFTDSTKLGPRSDTWSLGVLFAYMKGATLPW
... |  .|  .|    .   .|| |.|. ... . | |.      | ..    |.|     . .  ||       .|   | ||.|.|   .    ||.
FFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKTKGRKDYHNLQTC-CGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFLPF

NCSNVFTMVKKITNG--ELPTGLPEDCSANVERMLQVSPKNRPQIEDVIFDDNF
.  |.  | |||  |  | |  |       . .|||| || | .. ...  .  
DDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV
Kinase 86278.m00098.AA Ciliate-E2 43-248 14 2.6e-11 35.05 In-house 62-365 (365) Show / Hide 
Range on Protein: 43-248
Range on HMM: 62-365/365
Sequence Identity: 14% (47 aa)

FIDKIKHLQ-----------------DLNLTFIVNYTDILE--TETTIYLIRPYFNSQTLSSFLQ-----SPDKQH------DVNIVALWKTIAR-----
.| ...|.                   ||  .|... .  .  ....|||.  |.. ..| ....     .. ...      .  |  . | |..     
QIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTK

----------SIMILHNNN-ISSLPIKPSNILIFNEKFISLTDMYEIKSNI---------RWSLETIDRK------------------------HLLFIP
           .  ||..| |    |||.|||.     | ..|.   | .          . . . .. |                         . . .
AEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMA

PEFFT--------DSTKLGPRSDTWSLGVLFAYMKGATLPWNCSNVFTMVKKITNGELPTGLP----------------EDCSAN----VER----MLQV
|| .         ...  .  .| |||||.. .|    .|.         ..| ....    |                ...| .      .    |||.
PEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQK

SPKNRPQ-IEDVIFDDNF
 |..|.. .|...    |
DPEKRITGWEQILNHPWF
Kinase 86278.m00098.AA S_TKc 1-248 15 4.6e-11 -14.64 SMART 4-231 (231) Show / Hide 
Range on Protein: 1-248
Range on HMM: 4-231/231
Sequence Identity: 15% (43 aa)

MNDLSNGFLGKTFLLKHNESSGTFVCKMISKEFLGNSDMVKAFIDKIKHLQDLNLTFIVNYTDILETETTIYLIRPYFNS--QTLSSFLQSPDK------
.. .  |  || .. .|...   . .|.|.          . ..  |. |.  .  .||.. |. .. . .|..  | .    .| .....  .      
LRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

QHDVNIVALWKTIARSIMILHNNNISSLPIKPSNILIFNEKFISLTD-----MYEIKSNIRWSLETIDRKHLL----FIPPEFFTDSTKLGP-RSDTWSL
 .   .  . . |.. .  .|...|    .||.|||. .   | ..|      .               ...     ...|| .    . |. ..| ||.
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------------TTFCGTPWYMAPEVL----GYGKCKCDWWSC

GVLFAYMKGATLPWNCSNVFTMVKKITNGELPTGLPEDCSANVERMLQVSPKNRPQIEDVIF-------DDNF
|.... |     |.   ....| |||         ....   ....||. |..|| . ..         .  |
GCILYEMLCGYPPFP--QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 86278.m00098.AA AMPK 174-248 39 1.5e-10 27.56 In-house 178-254 (254) Show / Hide 
Range on Protein: 174-248
Range on HMM: 178-254/254
Sequence Identity: 39% (31 aa)

GPRSDTWSLGV-LFAYMKGATLPWNCSNVFTMVKKITNGE--LPTGLPEDCSANVERMLQVSPKNRPQIEDVIFDDNF
||  |.|| || |.| | ...||   .|. |  |||.|||  .|. | ....  ...|||| | .| .|.|.  .. |
GPEVDIWSCGVILYA-MLCGYLPFDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 86278.m00098.AA NuaK 174-242 36 2e-09 20.37 In-house 177-246 (252) Show / Hide 
Range on Protein: 174-242
Range on HMM: 177-246/252
Sequence Identity: 36% (26 aa)

GPRSDTWSLGVLFAYMKGATLPWNCSNVFTMVKKITNGEL--PTGLPEDCSANVERMLQVSPKNRPQIEDV
||  | ||||||   |   |.|   ..  ..|| |..|.   |.  | | .  .  ||.| |. |  |.|.
GPEVDCWSLGVLLYTMVYGTMPFDGHDFKHLVKQISQGAYYEPC-KPSDACMLIRWMLMVNPRRRATIYDI
Kinase 86278.m00098.AA CAMK 161-242 18 4e-09 24.79 In-house 285-419 (425) Show / Hide 
Range on Protein: 161-242
Range on HMM: 285-419/425
Sequence Identity: 18% (25 aa)

FIP-PEFFTD-------------STKLGPRSDTWSLGVLFAYMKGATLPWNCS-------------NVFTMVKKITNGELPTGLPE--------------
... || .                .  || .| ||.||.   |   ..|.. .             |   . .||..|.     |.              
YMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWD

------------DCSANVERMLQVSPKNRPQIEDV
            .|   . .|||| |..|. ||..
DISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQC
Kinase 86278.m00098.AA CAMKL 159-248 25 3.3e-08 22.15 In-house 197-297 (297) Show / Hide 
Range on Protein: 159-248
Range on HMM: 197-297/297
Sequence Identity: 25% (27 aa)

LLFIPPEFFTD--STKLGPRSDTWSLGVLFAYMKGATLPWNCS--------NVFTMVKKITNGELPTG----LPEDCSANVERMLQVSPKNRPQIEDVIF
. . .|| | .      ||  | ||.||.   |   .||...         |. .. .||  |         .. ||     .|||| |. || |...  
PPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMN

DDNF
.  .
HPWM
Kinase 86278.m00098.AA NIM1 164-248 27 4.7e-07 16.77 In-house 172-258 (258) Show / Hide 
Range on Protein: 164-248
Range on HMM: 172-258/258
Sequence Identity: 27% (24 aa)

PEFFTDSTKLGPRSDTWSLGVLFAYMKGATLPWNCSNVFTMVKKITNGE--LPTGLPEDCSANVERMLQVSPKNRPQIEDVIFDDNF
|| | |    |.  |.| ||.|  .|   . |     |  | | |. |.  .|  . . |   . .||.  |  |. |...  .   
PELFQDEHYIGEYVDVWALGILLYFMMTGVMPFRAETVPKMKKCILKGQYQIPDYVSLPCHRLIRGMLKHIPTQRYTIDQMMNHQWM
Kinase 86278.m00098.AA MARK 174-248 29 2e-06 17.56 In-house 184-262 (262) Show / Hide 
Range on Protein: 174-248
Range on HMM: 184-262/262
Sequence Identity: 29% (23 aa)

GPRSDTWSLGVLFAYMKGATLPWN--CSNVFTMVKKITNGELP--TGLPEDCSANVERMLQVSPKNRPQIEDVIFDDNF
||  |.|||||.  .|   ..|.   . .  .. |||..|. .  . .. .|   . |.|.| |. ||.||..  .  .
GPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 86278.m00098.AA Ciliate-E2-Unclassified 50-248 15 3e-06 17.66 In-house 75-352 (352) Show / Hide 
Range on Protein: 50-248
Range on HMM: 75-352/352
Sequence Identity: 15% (43 aa)

LQDLNLTFIVNYTDILETETTIYLIRPYFNSQTLSSFLQSPDK-----------------QHDVNIV-----ALWKTIARSIMILHNNN-ISSLPIKPSN
|....  |||.. .. ... .||..  |.. ..|. ....  |                   . ...      . . |   .  || .| |    |||.|
LLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPEN

ILIFNEK---FISLTDMYEIKSNI--------------RWSLETIDRK--HLLFI----PPEFFTDSTKLGPR---SDTWSLGVLFAYMKGATLPWNCSN
||. |..    | ..|   .| ..              .|. . .. .   . ..    .|| .      ..    .| |||||.. .|   ..| .. |
ILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNN

VFT----------------MVKKITNGELP----------TGLPEDCSANVE----RMLQVSPKNRPQIEDVIFDDNF
                   . ..| ....            .... .   ..    .||.. |..|...|...    |
CEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 86278.m00098.AA Ciliate-C3 77-140 33 3e-06 18.91 In-house 67-140 (140) Show / Hide 
Range on Protein: 77-140
Range on HMM: 67-140/140
Sequence Identity: 33% (25 aa)

YFNSQTLSSFLQSPD---KQHDVNIV-------ALWKTIARSIMILHNNNISSLPIKPSNILIFNEKFISLTDM
||. ||| .|..      |..| |          . | |   |  ||  ||    ||.|||||  .. | . | 
YFEGQTLEKFINEIYDNKKYQDQNHKDLKLQKLQISKQILQAIDYLHEHNIVHGDIKFSNILINSKDEIKIIDF
Kinase 86278.m00098.AA Pkinase 174-237 20 0.00076 14.68 Pfam 190-282 (293) Show / Hide 
Range on Protein: 174-237
Range on HMM: 190-282/293
Sequence Identity: 20% (19 aa)

GPRSDTWSLGVLFAYMKGATLPWNCS------NVFTMVKKITNGELPTGLP-----------------------EDCSANVERMLQVSPKNRP
||..| ||.|.....|    .|.  .      .   |...|  ..|.   |                       |.|   ....|.. || ||
GPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRP