Gene 93576.m00074 (T.vaginalis)

93576.m00074

Species: T.vaginalis
Alias: 93576.m00074, TvagK1023
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
93576.m00074.AA Protein None 101 None Fasta, JSON
93576.m00074.kin_dom Protein Kinase Domain None 92 None Fasta, JSON

Protein domain

Protein domains of 93576.m00074.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 93576.m00074.AA MARK 20-101 39 1.3e-29 94.09 In-house 108-189 (262) Show / Hide 
Range on Protein: 20-101
Range on HMM: 108-189/262
Sequence Identity: 39% (33 aa)

KYFTEISDALCYMHDQGIAHCDIKLSNILIDSFG--RAKLCDFGLAQFLKNANRINSTKIRGTLSYMSPEIMAGKGYDPFKADV
..|. |  |..|.|...|.|.|||. |||||. |   .|..|||..   .. .. |.    ||..||.|||. .| || .|.|.
RIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTF--CGTPPYMAPEIFLKKPYDGPKVDI
Kinase 93576.m00074.AA CAMKL 20-101 37 3.3e-29 90.23 In-house 131-219 (297) Show / Hide 
Range on Protein: 20-101
Range on HMM: 131-219/297
Sequence Identity: 37% (33 aa)

KYFTEISDALCYMHDQGIAHCDIKLSNILIDSFG--RAKLCDFGLAQFLK---NANRINSTKIRGTLSYMSPEIMAG--KGYDPFKADV
.||. | .|. |.|..||.| |||. |||.|. |   .|..|||.. . .   . .    .   |...||.||| .|  | || .|.|.
RYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDI
Kinase 93576.m00074.AA CAMK 11-101 21 3.3e-28 87.41 In-house 174-317 (425) Show / Hide 
Range on Protein: 11-101
Range on HMM: 174-317/425
Sequence Identity: 21% (31 aa)

KRVPIKTVTKYFTEISDALCYMHDQGIAHCDIKLSNILIDSF-----------------GRAKLCDFGLAQFLKNAN----------------------R
.|.. . . .||  | .|. |.|...|.|.|.|. |||.|.                  .  |..|||.|....  .                       
GRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEG

INSTKIRGTLSYMS-PEIMAG-------------KGYDPFKADV
   .   ||..||. ||.  |             | |...|.|.
QKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDM
Kinase 93576.m00074.AA AGC 21-96 25 2.3e-27 66.47 In-house 151-282 (395) Show / Hide 
Range on Protein: 21-96
Range on HMM: 151-282/395
Sequence Identity: 25% (34 aa)

YFTE-------ISDALCYMHD-QGIAHCD-IKLSNILIDSFGRAKLCDFGLAQFLKN-----------------------------------ANRIN---
|. |       |  || |.|. .|| | | .|. |||.|. |  ||.||||.  ..|                                   ..| |   
YAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQ

-----------STKIRG--TLSYMSPEIMAGKGYDP
            . . |  |  ||.|||     |..
EDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGK
Pkinase 93576.m00074.AA Pkinase 8-101 33 5.3e-23 82.41 Pfam 95-195 (293) Show / Hide 
Range on Protein: 8-101
Range on HMM: 95-195/293
Sequence Identity: 33% (35 aa)

LM---GKRV--PIKTVTKYFTEISDALCYMHDQGIAHCDIKLSNILIDSFGRA----KLCDFGLAQFLKNANRINSTKIRGTLSYMSPEIMAGKGYDPFK
..   ....  . ... .|...|  .| |.|..|| |.|.|..|||||. |      |.|||||| .... |    | . ||. ||.||.  |  |.. |
ISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

ADV
.|.
VDM
Kinase 93576.m00074.AA ULK 10-101 27 7e-23 76.76 In-house 124-239 (329) Show / Hide 
Range on Protein: 10-101
Range on HMM: 124-239/329
Sequence Identity: 27% (32 aa)

GKRVPIKTVTKYFTEISDALCYMHDQGIAHCDIKLSNILIDSF------------GRAKLCDFGLAQFLKNA----NRINSTK----IRGTLSYMSPEIM
.|| . . . ..|  |  .. ..|...| |.|||..||||.              |..|..|||.|... |     . . ...    ..||  ||.|.| 
KKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQIL

AGKG----YDPFKADV
 |.|    |. .|.|.
QGQGEQKPYYDYKCDI
Kinase 93576.m00074.AA Ciliate-E2-Unclassified 20-101 29 3.9e-22 73.59 In-house 147-253 (352) Show / Hide 
Range on Protein: 20-101
Range on HMM: 147-253/352
Sequence Identity: 29% (32 aa)

KYFTEISDALCYMHDQG-IAHCDIKLSNILIDSFG---RAKLCDFGLAQFLKNAN--------------RINSTKIRGTLSYM----SPEIMAGKGYDP-
.|| .| ..|.|.| .. | | |||..|||.|. |   . |..|||.. .... |              . ... . ||..||    .||.. |..||  
FYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHS

--FKADV
  .|.|.
KAYKCDI
Kinase 93576.m00074.AA TKL 24-101 21 6e-22 75.81 In-house 140-272 (364) Show / Hide 
Range on Protein: 24-101
Range on HMM: 140-272/364
Sequence Identity: 21% (29 aa)

EISDALCYMHDQG--------IAHCDIKLSNILIDSFGR--------------AKLCDFGLAQFLKN------------------ANRINSTKIRGTLSY
.|. ...|.| ..        |.|.|.| .|||.|. ..              .|.|||||..|...                   || .. ...||. .
DIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRW

MSPEIMAGKGYDP---------------FKADV
|.||.. |.....                |.||
MAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDV
Kinase 93576.m00074.AA ULK 10-101 28 1.2e-21 73.65 In-house 120-235 (324) Show / Hide 
Range on Protein: 10-101
Range on HMM: 120-235/324
Sequence Identity: 28% (33 aa)

GKRVPIKTVTKYFTEISDALCYMHDQGIAHCDIKLSNILIDSF------------GRAKLCDFGLAQFLKN----ANRINSTK----IRGTLSYMSPEIM
.|| . . . ..|  |  .. ..|...| |.|||..||||               |..|..|||.|... |    .. . ...    |.||  ||.|.| 
KKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQIL

AGKG----YDPFKADV
 |.|    |. .|.|.
QGQGEQKPYYDYKCDI
Kinase 93576.m00074.AA Ciliate-E2 11-101 24 1e-20 67.8 In-house 140-279 (365) Show / Hide 
Range on Protein: 11-101
Range on HMM: 140-279/365
Sequence Identity: 24% (35 aa)

KRVPIKTVTKYFTEISD---------------ALCYMHDQG-IAHCDIKLSNILIDSFGRAKLCDFGLAQFLKNANRINS--------------------
|.  .| . .....| .               || |.| .. | | |||..|||.      |..||||...... |  ..                    
KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGY

----------TKIRGTLSYMSPEIMAGKGYDP--------FKADV
            | ||. ||.|||  ||.||         .|.|.
MDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDI
Kinase 93576.m00074.AA RSK 16-95 32 6.4e-19 66.07 In-house 104-190 (278) Show / Hide 
Range on Protein: 16-95
Range on HMM: 104-190/278
Sequence Identity: 32% (28 aa)

KTVTKYFTEISDALCYMHDQGIAHCDIKLSNILIDS---FGRAKLCDFGLAQFLKNANRINSTKIRGTLSYMSPEIMA----GKGYD
...  |. ||. |. ..|.||| | |.|..||| |.    |. ||.|||..  ... .     . ..|. || ||. .    ..|.|
DEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHD
S_TKc 93576.m00074.AA S_TKc 1-98 14 0.000215 -112.48 SMART 1-231 (231) Show / Hide 
Range on Protein: 1-98
Range on HMM: 1-231/231
Sequence Identity: 14% (36 aa)

MIL-----------------------------------------------------------------------SCAPLMGKR--------VPIKTVTKY
  .                                                                       .   .. ||         |  .. .|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFY

FTEISDALCYMHDQGIAHCDIKLSNILIDSFGRAKLCDFGLAQFLKNANRINSTKIRGTLSYMSPEIMAGKGY---------------------------
. .| .|| |.|..|| |.|.| .|||.|.  . |.|||||| .|        | . ||. ||.||.. | |.                           
MYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL-GYGKCKCDWWSCGCILYEMLCGYPPFPQMQM

---------------------------------------DPFK
                                       .|. 
MFKKIGSPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF