Gene TVAG_134240 (T.vaginalis)
TVAG_134240
Species: T.vaginalis
Alias: TVAG_134240, TvagK1049
External Links:
Annotation:
Group:
Other
Family:
Other-Tvag3
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| TVAG_134240.AA | Protein | None | 2082 | None | Fasta, JSON |
| TVAG_134240.kin_dom | Protein Kinase Domain | None | 437 | None | Fasta, JSON |
Protein domains of TVAG_134240.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| IQ | TVAG_134240.AA | IQ | 12-32 | 38 | 0.001154 | 15.74 | Pfam | 1-21 (21) | Show / Hide |
Range on Protein: 12-32 Range on HMM: 1-21/21 Sequence Identity: 38% (8 aa) IDVVVRIQSIFRGYSYRKHLS . ...||. .||| |||. HRAAIKIQAWWRGYLARKHYR |
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| IQ | TVAG_134240.AA | IQ | 38-58 | 38 | 0.039813 | 10.76 | Pfam | 1-21 (21) | Show / Hide |
Range on Protein: 38-58 Range on HMM: 1-21/21 Sequence Identity: 38% (8 aa) NRNALKIQNAWKFHLMRQKIQ | |.||| .|. .|.|.. . HRAAIKIQAWWRGYLARKHYR |
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| Kinase | TVAG_134240.AA | Dicty3 | 1199-1224 | 34 | 6.3e-08 | 22.04 | In-house | 326-351 (351) | Show / Hide |
Range on Protein: 1199-1224 Range on HMM: 326-351/351 Sequence Identity: 34% (9 aa) SKLFIEIIATCLQIDPAKRPPIEQLL |... ..| |.|||| .|. ...|. SNFCKNFIQHCWQIDPNHRWDMHELI |
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| Kinase | TVAG_134240.AA | Ciliate-E2 | 1010-1229 | 12 | 1.4e-07 | 22.1 | In-house | 176-365 (365) | Show / Hide |
Range on Protein: 1010-1229
Range on HMM: 176-365/365
Sequence Identity: 12% (37 aa)
LHSKN-IILRTLYPDNIYLNGFQNQVMIGSLLDSQFLESQLAIPLPPKFTDYRN----------------------------------------------
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LHSKNNIIHRDIKPENILF---------------------------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTIC
---PFLPPEFFHKKASE-------WTTAFDVWQFGMLLLYILTGNLPKSYGEVLMSSLSQETIKKCQSEKQSFEGVLDENVIYPKPNFFYDWLEDFKVVS
....|| . .| . .... |.| .|..| . |.|..|
GTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF----------------------------------------------------
SLEKCTGECGEVFIQTDECNIKYSSILQLEHYSLLPYKNTKLNYD--------------------ESKLFIEIIAT----CLQIDPAKRPP-IEQLLRTY
. |. |.... |. . .| .|| || ||. .||.|
---------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHP
PF
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WF
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| Kinase | TVAG_134240.AA | STE | 1199-1230 | 48 | 2.2e-07 | 22.25 | In-house | 327-359 (359) | Show / Hide |
Range on Protein: 1199-1230 Range on HMM: 327-359/359 Sequence Identity: 48% (16 aa) SKLFIEIIATCLQIDPAKRPPIEQLLRT-YPFN |. |.. |. |||.|| ||| .|||. || SPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI |
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| Kinase | TVAG_134240.AA | STE20 | 1199-1230 | 46 | 3e-06 | 19.07 | In-house | 258-288 (288) | Show / Hide |
Range on Protein: 1199-1230 Range on HMM: 258-288/288 Sequence Identity: 46% (15 aa) SKLFIEIIATCLQIDPAKRPPIEQLLRTYPFN |. | . ...|||.||.||| .|||. || SPEFHDFVDKCLQKDPEKRPTASQLLK-HPFI |
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| Kinase | TVAG_134240.AA | NKF1 | 1079-1099 | 52 | 5e-06 | 16.79 | In-house | 186-206 (269) | Show / Hide |
Range on Protein: 1079-1099 Range on HMM: 186-206/269 Sequence Identity: 52% (11 aa) TAFDVWQFGMLLLYILTGNLP .. |||||| |. ..|||..| PSHDVWQFGVLIFCCLTGCFP |
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| Kinase | TVAG_134240.AA | FRAY | 1199-1229 | 41 | 7e-06 | 13.9 | In-house | 247-277 (277) | Show / Hide |
Range on Protein: 1199-1229 Range on HMM: 247-277/277 Sequence Identity: 41% (13 aa) SKLFIEIIATCLQIDPAKRPPIEQLLRTYPF ...| ..| ||| ||.||| ||. | GHSFKKMIEKCLQKDPSKRPTASELLKHKFF |
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| Kinase | TVAG_134240.AA | RCK | 1203-1230 | 39 | 1.5e-05 | 13.23 | In-house | 272-298 (298) | Show / Hide |
Range on Protein: 1203-1230 Range on HMM: 272-298/298 Sequence Identity: 39% (11 aa) IEIIATCLQIDPAKRPPIEQLLRTYPFN ||.. .||.|| ||. ..|.|. .|. IELMEKMLQWDPQKRITAQQALQ-HPYF |
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| Kinase | TVAG_134240.AA | PLK2 | 1204-1229 | 34 | 1.7e-05 | 13.39 | In-house | 232-257 (257) | Show / Hide |
Range on Protein: 1204-1229 Range on HMM: 232-257/257 Sequence Identity: 34% (9 aa) EIIATCLQIDPAKRPPIEQLLRTYPF ..|| | ||. ||......| | HLIARMLSPDPEDRPSLDHIIRHDFF |
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| Kinase | TVAG_134240.AA | CDKL | 1199-1229 | 32 | 2.8e-05 | 14.01 | In-house | 256-286 (286) | Show / Hide |
Range on Protein: 1199-1229 Range on HMM: 256-286/286 Sequence Identity: 32% (10 aa) SKLFIEIIATCLQIDPAKRPPIEQLLRTYPF .|. . .. ||..||..|. |||.. | NKKALDFMKKCLHMDPDERMTCEQLMHHPYF |
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| Kinase | TVAG_134240.AA | Ciliate-D1 | 1082-1100 | 42 | 3e-05 | 18.37 | In-house | 1-19 (19) | Show / Hide |
Range on Protein: 1082-1100 Range on HMM: 1-19/19 Sequence Identity: 42% (8 aa) DVWQFGMLLLYILTGNLPK |.|.||..|...|.|. | DIWSFGCILYEMLFGQPPF |
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| S_TKc | TVAG_134240.AA | S_TKc | 828-1229 | 11 | 7.6e-05 | -105.86 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 828-1229
Range on HMM: 1-231/231
Sequence Identity: 11% (48 aa)
EILGDLVKHELMKRVQESINKSFEKNLLDKMLPVQPIDLKLTQKEPDPNIKFCQMPFRNPELTEIFHRTSFELFPTHVQYGRDMDQKQFLRMFVLTPEIY
..... . . .| ..|. . |...
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------------------------------------------------------------
KKLSVQIDNVSKYSFVSRKVSICIPQVMTSSTEGFTKIVMTEDMKSL---PLSYFLKVHSFLGAD-PRLLSVAKSICSRCLSMLYNLHSKNIILRTLYPD
.. . . .. | . . . ... | .. . | ..| . | . | .|.... .. | .||..|| | | |.
------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPE
NIYLNGFQNQVMIGSLLDSQFLESQLAIPLPPKFTDYRNPF------LPPEFFHKKASEWTT-AFDVWQFGMLLLYILTGNLPKSYGEVLMSSLSQETIK
|| |. ...|. . .| . | ..|| . ... . |.| .| .| |.| | . |...|
NILLDE---HIKICDFGLARQL----------------TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCILYEMLCGYPPFP--------QMQMMFK
KCQSEKQSFEGVLDENVIYPKPNFFYDWLEDFKVVSSLEKCTGECGEVFIQTDECNIKYSSILQLEHYSLLPYKNTKLNYDESKLFIEIIATCLQIDPAK
|. |. ....| ||| ||.|
KIG-------------------------------------------------------------------------------SPEAKDFIRKCLQKDPEK
RPPIEQLLR-------TYPF
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RPTA-EALQDEWDIKCHPWF
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