Gene 86997.m00231 (T.vaginalis)

86997.m00231

Species: T.vaginalis
Alias: TvagK0920, 86997.m00231
External Links:
Annotation:

Classification

Group: Other
Family: CDC7

Sequence

Name Sequence Type Origin Length Description Download
86997.m00231.AA Protein None 328 None Fasta, JSON
86997.m00231.kin_dom Protein Kinase Domain None 311 None Fasta, JSON

Protein domain

Protein domains of 86997.m00231.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 86997.m00231.AA S_TKc 15-325 23 5.2e-70 239.81 SMART 1-231 (231) Show / Hide 
Range on Protein: 15-325
Range on HMM: 1-231/231
Sequence Identity: 23% (76 aa)

FTIIGTIGVGSFSTVVKATNKK-GAMFALKKLFWNNSPDRIVKEIQWLNKLDHPNIVQLYGAYRAHDQATLVMGYVPH--TSFRSLLQN---------MT
..|. .|| |.|..| |...|| |  .|.|..      ..| .||| | | .|||||.||....  |   .|| |...   . ......         ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

CKIIKDYMRGLLSALQYLHSHKIIHRDVKPANFLFDPETGNGSLIDFGLCEEDNHPPPPQSTFAQSDYDDNDYDFNFPQLCQGRPKMQANRAGTRGFRAP
   .. ||. ...||.|.|||.|||||.||.| |.|    .  ..||||. .                                        ||. ..||
E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL-----------------------------------TTFCGTPWYMAP

EVLISYQNQTSAIDMWSTGVVLLSMLSGRYPFFKSPDDLTSLCEVSTIIGTKRLHEAAKLCRRKIHFPREQEGIAFPDLVKGLNPYFDQLGCDESVFDLL
|||   .  . ..|.|| |..|  ||.|. ||     ..  . ..                                               .... |..
EVL---GYGKCKCDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG---------------------------------------------SPEAKDFI

GRLMDPSPYTRITAEDALR-------HEFL
 ....  |  |.|| .||.       |...
RKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase 86997.m00231.AA Pkinase 15-325 24 2.7e-58 204.8 Pfam 1-293 (293) Show / Hide 
Range on Protein: 15-325
Range on HMM: 1-293/293
Sequence Identity: 24% (82 aa)

FTIIGTIGVGSFSTVVKATNKKGAM-FALKKLFWNNSPDRIVK------EIQWLNKLDHPNIVQLYGAYRAHDQATLVMGYVPHT----SFRSLLQ----
..|...|| |||..| |...|.    .|.|..   .  .   .      ||| ...|.|||||.||.... .|   .|| |....    .  ....    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

-NM--TCKIIKDYMRGLLSALQYLHSHKIIHRDVKPANFLFDPETGNG----SLIDFGLCEE-DNHPPPPQSTFAQSDYDDNDYDFNFPQLCQGRPKMQA
 ..  . . .|.||. .|..|.|.||..|||||.||.|.|.| ..|.      ..||||..  |                              .     
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFD----------------------------Y-NNS-MT

NRAGTRGFRAPEVLISYQNQTSAIDMWSTGVVLLSMLSGRYPFFKS---PDDLTSLCEVSTIIGTKRLHEAAKLCRRKIHFPREQEGIAFPDLVKGLNPY
 ..||....||||. ..|  ....|||| |..|  ||.|| ||  .   .. .. .  .  | |..   .  ..|..   | . .   .         . 
TFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-------F-HW

FDQLGCDESVFDLLGRLMDPSPYTRITAEDALRHEFL
.     .|.  |.. .. .. |. |.|||..| |...
TF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 86997.m00231.AA CDC7 15-156 34 9.6e-55 161.29 In-house 1-160 (522) Show / Hide 
Range on Protein: 15-156
Range on HMM: 1-160/522
Sequence Identity: 34% (55 aa)

FTIIGTIGVGSFSTVVKATNKKGA---------------MFALKKLFWNNSPDRIVKEIQWLNKLD-HPNIVQLYGAYRAHDQATLVMGYVPHTSFRSLL
....  || | ||.| ||| ...                 ||.|...  ..|.|| .|.| | ..  |.|.... .. |  |....|| | || ||. ..
YKVHDKIGEGTFSSVYKATCQRQPHVNKFASHFWNYCRRKFAIKHHIPTSHPERIMNELQCLTRMGGHHNVMGMCCCFRYNDHVHIVMPYFPHCSFQDFY

QNMT--CKIIKDYMRGLLSALQYLHSHKIIHRDVKPANFLFDPETGNGSLIDFGLCEEDN
  |.   . ||.||. |. || ..|.  |||||||| |||. ..|. . |.|||| ....
FHMNRDMEEIKHYMYNLFYALRHVHQFGIIHRDVKPSNFLYNRRTKKFLLVDFGLAQHMM
Kinase 86997.m00231.AA Ciliate-E2 15-325 21 1.1e-53 182.59 In-house 1-365 (365) Show / Hide 
Range on Protein: 15-325
Range on HMM: 1-365/365
Sequence Identity: 21% (88 aa)

FTIIGTIGVGSFSTVVKATN-KKGAMFALK----------------------KLFWNNSPDRIVKEIQWLN----------------KLDHPNIVQLYGA
. .|  || |.|..| |... |.. .||.|                      | . .|    | .||. ..                .|.||||...| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YR--AHDQATLVMGYVPHTSFRSLLQ--------------NMTCKIIKDYMRGLLS---------------ALQYLHSHK-IIHRDVKPANFLFDPETGN
.     .   ||| |. . . .....              ..|.| ||..|. .|.               ||.|||| . ||||| || | ||      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

GSLIDFGLCEEDNHPPPPQSTFAQSDYDDNDYDFNFPQLCQGRP----------------KMQANRAGTRGFRAPEVLI--SYQN------QTSAIDMWS
  .|||||.           .... |.... . ..  ....                    |. . .|| |. |||.|   .|.|       . ..|.||
IKIIDFGLS-----------KKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWS

TGVVLLSMLSGRYPFFKSPDDLTSLCEVSTIIGTKRLHEAAKLCRRKIHFPREQEGIAFPDLVKGLNPYF-DQLGCDESVFDLLGR----LMDPSPYTRI
 ||.|  ||.|..||                          . .  || || .. .    .  . . .   . . ..... ||. .    ...  |  ||
LGVILYEMLFGKPPF------------------------QQQIKQCKIDFPCPEWQKD-TQ-CI-Q-CKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRI

T-AEDALRHEFL
| .|..| |...
TGWEQILNHPWF
Kinase 86997.m00231.AA CMGC 15-325 17 6.9e-52 168.29 In-house 1-513 (513) Show / Hide 
Range on Protein: 15-325
Range on HMM: 1-513/513
Sequence Identity: 17% (92 aa)

FTIIGTIGVGSFSTVVKATNKK---------------GAMFALKKLFWNNSPD--------------RIVKEIQWLNKL-----------------DHPN
..||. || |....|.|...|.               . . |.||.. .   .              |.  ||. | .|                 .|.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVQLYGAYRAHD-----------------QATLVMGYVPHTSFRSLLQN------------------------------MTCKIIKDYMRGLLSALQ--Y
||.||  .. ..                 .  ||. |..|. .. . .|                              ..   |. ||. .| .|   |
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKY

LHSHK--IIHRDVKPANFLFDPET-------------------GNGSLIDFGLCEEDNHP------PPPQSTFAQSDYDDNDYDFNFPQLCQGRPK----
.|||.  ||||| ||.| |.....                   |.  ..||||.   ...      . ||| |                      |    
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQS-F----------------------KNVNK

------MQANRAGTRGFRAPEVLISYQNQT---------SAIDMWSTGVVLLSMLSG-------RYPFFK-----------SPDDLTSLCEVSTIIG---
      .  ..  ||  ||||.|..... |         ..||||| | ..  |. |       ..|.|.             ...  | .   ..|   
DDKPNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT

---------------TKRLHEAAKLCRRK--------------IHFPREQEGIAFPDLVKGLNPYFDQL-------------------------------
               ..   .  || ...              .     .    .... .   . . .|                               
WMIQKGKRHFNFCKHEEEWPNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFN

------GCDESVFDLLGRLMDPSPYTRITAEDALRHEFL
       ||.  .||| ...   |  |||||.||.|...
HQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase 86997.m00231.AA CDC7 182-267 52 5.9e-45 131.38 In-house 317-402 (522) Show / Hide 
Range on Protein: 182-267
Range on HMM: 317-402/522
Sequence Identity: 52% (45 aa)

LCQGRPKMQANRAGTRGFRAPEVLISYQNQTSAIDMWSTGVVLLSMLSGRYPFFKSPDDLTSLCEVSTIIGTKRLHEAAKLCRRKI
.|  .  . ||||||.||||||||  . .|| |||.|| ||..||.||||||||..|||.|.| .  ||.|..   ..|..   ||
CCMCPKQQHANRAGTPGFRAPEVLLKCPDQTTAIDIWSCGVIFLSLLSGRYPFFMAPDDMTALAQIMTIFGSEEIIKMAHFFGKKI
Kinase 86997.m00231.AA Ciliate-E2-Unclassified 15-235 23 1.2e-34 117.56 In-house 1-271 (352) Show / Hide 
Range on Protein: 15-235
Range on HMM: 1-271/352
Sequence Identity: 23% (67 aa)

FTIIGTIGVGSFSTVVKATNKKGAMFA------------LKKLFWNNSPDRIVKEIQWLNK------------------LDHPNIVQLYGAYRAHDQATL
..|| .|| |.|..| |. .||   ..             .|.  |.  . . ..... ||                  ..||.|| .. . .  .   .
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VMGYVPHTSFRSLLQN--------------------MTCKIIK-----DYMRGLLSALQYLHSHK-IIHRDVKPANFLFDPETG--NGSLIDFGLCEEDN
|| |... . .  ...                     |.. .|     .|.. .|..|.|||. . ||||| || | ||| . .  .  .||||.. . .
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

HPPPPQSTFAQSDYDDNDYDFNFPQLCQGRPKMQANRAGTRGFR----APEVLIS--YQNQTS-AIDMWSTGVVLLSMLSGRYPFF
 ..  . |. |            ... . ...|.  ..|| ..     ||||| .  | .... ..|.|| ||.|  || |.|||.
QNNNCD-TNQQ------------QKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFY
Kinase 86997.m00231.AA CAMKL 15-234 25 7.9e-34 105.23 In-house 1-236 (297) Show / Hide 
Range on Protein: 15-234
Range on HMM: 1-236/297
Sequence Identity: 25% (66 aa)

FTIIGTIGVGSFSTVVKATN-KK-GAMFALKKLFWNNSPD-----------------RIVKEIQWLNKLD---HPNIVQLYGAYRAHDQ------ATLVM
..|. |.| |||..|  ||. .  | . | | .  .   .                 || .||| . .|.   ||||..||  .   .         |||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

GYVPHTS--FRSLLQ-N------MTCKIIKDYMRGLLSALQYLHSHKIIHRDVKPANFLFDPETG-NGSLIDFGLCEE-D-NHPPPPQSTFAQSDYDDND
 |..  .      .. .      |. .  . | | ..||..|.|||.|.||| || | |.|     |  .||||.. . . .                  
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPC------------------

YDFNFPQLCQGRPKMQANRAGTRGFRAPEVLIS--YQNQTSAIDMWSTGVVLLSMLSGRYPF
          |. ..   . |.  . |||.. .   .    ..|.|| ||.|  |. |..||
--------IFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPF
Kinase 86997.m00231.AA STE 15-152 28 9.2e-33 113.05 In-house 1-194 (359) Show / Hide 
Range on Protein: 15-152
Range on HMM: 1-194/359
Sequence Identity: 28% (57 aa)

FTIIGTIGVGSFSTVVKATNKK----------------GAMFALKKL-----------------FWNNSPDR--IVKEIQWLNKLD--HPNIVQLYGAYR
...|. || |.| ||.|| |.|                | ..| |..                  . |. ..  | |||. ..|..  |||||. ||.| 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

AH-------DQATLVMGYVPHTSFRSLLQ-NMTC----------------KIIKDYMRGLLSA-LQYLHSHKIIHRDVKPANFLFDPETGNGSLIDFGLC
         |.  ..| |..  |...... .. |                ..|. . | .| . |.|||||.|||||.|||| |.        |.|||.|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL------VKLCDFGVC
Kinase 86997.m00231.AA Ciliate-E2a 15-234 27 1.3e-32 93.36 In-house 1-216 (275) Show / Hide 
Range on Protein: 15-234
Range on HMM: 1-216/275
Sequence Identity: 27% (68 aa)

FTIIGTIGVGSFSTVVKA----TNKKGAMFALKKLFWNNS--PDRIVKEIQWLNKLDHPNIVQLYGAYRAHDQATLVMGYVPHTSFR---SLLQNMTCK-
. .|  || |.|  |..|    |.|. || ...| . ..      . .||. . .|||||| .||. |  ...  ||| |.   .     .  .... . 
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEI

-IIKDYMRGLLS-ALQYLHSHKIIHRDVKPANFLFD---PET---GNGSLIDFGLCEED--NHPPPPQSTFAQSDYDDNDYDFNFPQLCQGRPKMQANRA
  |.|.|. ||. .|.|.|. .|.||| || |.||.   ..     .  .||||| .    .                              .|    . 
QEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKD-----------------------------EKKYMFQKC

GTRGFRAPEVLISYQ---NQ--TSAIDMWSTGVVLLSMLSGRYPF
|| |. ||||| . .   ..  .   |||| ||..  .|.|. ||
GTPGYVAPEVLNNKEVLKHKQYDTKCDMWSCGVIFYILLCGKPPF
Kinase 86997.m00231.AA CAMK 20-151 20 3.7e-32 100.37 In-house 1-242 (425) Show / Hide 
Range on Protein: 20-151
Range on HMM: 1-242/425
Sequence Identity: 20% (49 aa)

TIGVGSFSTVVKATNK-KG------------AMFALKKLF----------------------------W--NNSPDRIVKEIQWLNK-------LDHPNI
|.| |||..| ....|  .              .| | .                             |   .. ... .||. ..|       ||||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQLYGAYR------------AHDQ--------ATLVM---GYVPHT----S-FRSLLQN-----------------MTCKIIKDYMRGLLSALQYLHSHK
..|| .|               ..          .||    |..        |  . ..                 .| .  . |.| ..||..|.|||.
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IIHRDVKPANFLFDPET----------------GNGSLIDFGL
|.||| || | |.|                   .|  .||||.
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGF
Kinase 86997.m00231.AA CDK 15-151 29 1.3e-27 85.33 In-house 1-159 (284) Show / Hide 
Range on Protein: 15-151
Range on HMM: 1-159/284
Sequence Identity: 29% (50 aa)

FTIIGTIGVGSFSTVVKATNKK-G-----AMFALKKLFWNN-----SPDRIV----KEIQWLNKLDHPNIVQLYGAYRAHDQA-----------TLVMGY
. ..  || |.. .| || .|. |      . ||||.   |       . .      ||  | .| |||||.|.  .  .. .           ..|. |
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

VPHTSFRSLLQNMTCKIIKDYMRGLLSALQYLHSHKIIHRDVKPANFLFDPETGNGS-------LIDFGL
..|    ...       || ||. ||..| |.||..|.||| ||.| | .    ||.       . ||||
MDHD-LKKYMD------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILIN---NNGEVKCGRLKIADFGL
Kinase 86997.m00231.AA CK2 15-153 37 2.2e-27 78.18 In-house 1-144 (288) Show / Hide 
Range on Protein: 15-153
Range on HMM: 1-144/288
Sequence Identity: 37% (54 aa)

FTIIGTIGVGSFSTVVKATNKKGAMFA--LKKLFWNNSPDRIVKEIQWLNKLD-HPNIVQLYGAYRAHDQATL--VMGYVPHTSFRSLLQNMTCKIIKDY
. .|  || | .| | .. |.|       . |.   .   .|  ||. |..|  .|||..||.  .  .  .   |  ||  | || | | .|   |. |
YEVIRKIGRGKYSEVFEGINIKNNEKCKIVIKILKPVKKKKIKREIKILENLNGGPNIIKLYDIVKDPYSKVPALVFEYVNNTDFRQLYQTLTDYDIRYY

MRGLLSALQYLHSHKIIHRDVKPANFLFDPETGNGSLIDFGLCE
|. || || | ||  |.||||||.| . |.|    .||| || |
MFELLKALDYCHSMGIMHRDVKPHNIMIDHEKRKLRLIDWGLAE
Kinase 86997.m00231.AA CK2 193-325 25 3.1e-23 65.54 In-house 155-288 (288) Show / Hide 
Range on Protein: 193-325
Range on HMM: 155-288/288
Sequence Identity: 25% (35 aa)

RAGTRGFRAPEVLISYQNQTSAIDMWSTGVVLLSMLSGRYPFFKSPDDLTSLCEVSTIIGTKRLHEAAKLCRRKIHFPREQEGIAFPDLVKGLNPYFD--
| ..| ...|| |. ||    ..||||.|... ||.  . |||.  |  . | .. ...||. |..   | . .|| ..... |      |... . .  
RVASRYYKGPELLVDYQYYDYSLDMWSLGCMFASMIFKKEPFFHGHDNYDQLVKIVKVLGTEDLYKY--LDKYGIHLDPQFHDIMQQHKKKPWERFIHQE

-QLGCDESVFDLLGRLMDPSPYTRITAEDALRHEFL
 .  ... . |.| ...   .  |||| .|. |.. 
NKHLAHPEAIDFLDKMLRYDHQERITAKEAMEHPYF
Kinase 86997.m00231.AA Pkinase_Tyr 15-130 26 5.4e-12 41.25 Pfam 1-137 (270) Show / Hide 
Range on Protein: 15-130
Range on HMM: 1-137/270
Sequence Identity: 26% (36 aa)

FTIIGTIGVGSFSTVVKATNK-----KGAMFALKKLFWNNSPDR------IVKEIQWLNKL-DHPNIVQLYGAYR-AHDQ--ATLVMGYVPHTSFRSLLQ
 |.. ..| |.| .|.|.| |     ..   | |.|  ... ..        .|.. . .| .|||||.|||.     ..    .|| |.|| . .. |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

NM-------TCKIIKDYMRGLLSALQYLHSHKIIHRDV
.        | | . .. .   ....||.|...||||.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL
Kinase 86997.m00231.AA CDC7 299-325 51 5.4e-12 30.64 In-house 496-522 (522) Show / Hide 
Range on Protein: 299-325
Range on HMM: 496-522/522
Sequence Identity: 51% (14 aa)

FDLLGRLMDPSPYTRITAEDALRHEFL
.|||.|. .. | .|||||.|| | |.
YDLLDRCLEMNPHKRITAEEALKHPFF
Kinase 86997.m00231.AA TyrKc 15-325 17 3e-09 -73.02 SMART 1-280 (280) Show / Hide 
Range on Protein: 15-325
Range on HMM: 1-280/280
Sequence Identity: 17% (60 aa)

FTIIGTIGVGSFSTVVKATNKKGAMFALKKLFWNNSPDRIVKEIQWLNKL--DHPNIVQLYGAYRAH-------DQATLVMGYVPHTSFRSLLQNMT---
 | . ..| | | .|.|.| |   . | |.|  .     . .|.. . ||  .|||||.|||. . .       ..  .|| |.|| . .. |..     
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKL

-CKIIKDYMRGLLSALQYLHSHKIIHRDVKPANFLFDPETGNGSLIDFGLCEEDNHPPPPQSTFAQSDYDDNDYDFNFPQ-------LCQGRPKM-----
  |   ...    .  .||||...||||    | | . .                                        .       |.           
CMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---------------------------------------TVKISDFGLSRDIYDDDQQGE

--QANRAGT-RGFR--------APEVLISYQNQTSAIDMWSTGVVLLSMLSGRYPFFKSPDDLTSLCEVSTIIGTKRLHEAAKLCRRKIHFPREQEGIAF
  .  |. . .| .        |||..  |   |.. | || ||..  ...   .    .      .. . .|  ... .   . . . .     . .. 
SKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ--MMSNQEVI--EYVKQGYRMPQPPNDY----P-MS-

PDLVKGLNPYFDQLGCDESVFDLLGRLMDPSPYTRITAEDALRHEFL
          |   .| . ....  .  .  |  | | ..   ||..
----------F--VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 86997.m00231.AA Ciliate-E2a 294-325 34 5e-09 22.75 In-house 244-275 (275) Show / Hide 
Range on Protein: 294-325
Range on HMM: 244-275/275
Sequence Identity: 34% (11 aa)

CDESVFDLLGRLMDPSPYTRITAEDALRHEFL
|. . .||. .. .. |  ||||..|| | . 
CSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase 86997.m00231.AA CAMK 195-234 35 1.1e-08 23.34 In-house 281-334 (425) Show / Hide 
Range on Protein: 195-234
Range on HMM: 281-334/425
Sequence Identity: 35% (19 aa)

GTRGFRA-PEVLIS-------------YQNQTSAIDMWSTGVVLLSMLSGRYPF
|| .. | |||| .              .  . ..|||| ||.|  ||.|..||
GTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPF
Kinase 86997.m00231.AA CDK 287-325 30 1.3e-07 20.3 In-house 256-284 (284) Show / Hide 
Range on Protein: 287-325
Range on HMM: 256-284/284
Sequence Identity: 30% (12 aa)

PYFDQLGCDESVFDLLGRLMDPSPYTRITAEDALRHEFL
|..          ||| ...   |. ||.||.|| |...
PDY----------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase 86997.m00231.AA CAMK 300-325 30 8.3e-05 10.63 In-house 400-425 (425) Show / Hide 
Range on Protein: 300-325
Range on HMM: 400-425/425
Sequence Identity: 30% (8 aa)

DLLGRLMDPSPYTRITAEDALRHEFL
||. ... . |  |.|.|..|.|...
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 86997.m00231.AA CDK 200-234 32 0.000232 9.68 In-house 186-225 (284) Show / Hide 
Range on Protein: 200-234
Range on HMM: 186-225/284
Sequence Identity: 32% (13 aa)

RAPEVLISYQNQT--SAIDMWSTGVVLLSMLS---GRYPF
||||.|   .. .   .||||| | ..  |.    ... |
RAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLF
Kinase 86997.m00231.AA CAMKL 300-325 23 0.00123 7.31 In-house 272-297 (297) Show / Hide 
Range on Protein: 300-325
Range on HMM: 272-297/297
Sequence Identity: 23% (6 aa)

DLLGRLMDPSPYTRITAEDALRHEFL
||. ... . |  |.|... ..|...
DLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 86997.m00231.AA Ciliate-E2-Unclassified 300-325 38 0.00124 8.5 In-house 327-352 (352) Show / Hide 
Range on Protein: 300-325
Range on HMM: 327-352/352
Sequence Identity: 38% (10 aa)

DLLGRLMDPSPYTRITAEDALRHEFL
||| ....  |  |||.|..| | ..
DLLQKMLKKNPNKRITFEQILNHPWF
Kinase 86997.m00231.AA STE 194-238 27 0.004537 6.83 In-house 224-273 (359) Show / Hide 
Range on Protein: 194-238
Range on HMM: 224-273/359
Sequence Identity: 27% (14 aa)

AGTRGFRAPEVLIS-----YQNQTSAIDMWSTGVVLLSMLSGRYPFFK-SP
.||  . ||||.        .  .   |.|| | ... |. |..|... .|
VGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHP
Kinase 86997.m00231.AA STE 313-325 40 0.073169 2.51 In-house 345-359 (359) Show / Hide 
Range on Protein: 313-325
Range on HMM: 345-359/359
Sequence Identity: 40% (6 aa)

RITAEDALR--HEFL
| ||.. |.  |.|.
RPTASQLLKSEHPFI