Gene 82699.m00089 (T.vaginalis)

82699.m00089

Species: T.vaginalis
Alias: 82699.m00089, TvagK0372
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
82699.m00089.AA Protein None 435 None Fasta, JSON
82699.m00089.kin_dom Protein Kinase Domain None 255 None Fasta, JSON

Protein domain

Protein domains of 82699.m00089.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH 82699.m00089.AA PH 18-112 25 1e-07 32.87 SMART 1-82 (82) Show / Hide 
Range on Protein: 18-112
Range on HMM: 1-82/82
Sequence Identity: 25% (24 aa)

PIFSSELKKKEGPLEMWKTCRCELYKKSIVI-KQGFSNPLIQNIDLSSKLEVNEIPSNVRYQFSIKSHNSTIYFLTENNNIFHQWVDAIRSILLSN
.| .  |.||.  .  || . . |. ..... |.     ..  |.||.  .|.| |      | |.. . |.|| .|.   ...|..||.. . .|
VIKEGWLYKKS--K-RWKKRWFVLFNDCLYYYKDK---KPKGSIPLSDC-TVRE-P-----CFEIHH-DRTYYFQCESEEEMQEWMQAIQKAIHNN
PH 82699.m00089.AA PH 18-110 24 1.3e-05 22.88 Pfam 1-92 (92) Show / Hide 
Range on Protein: 18-110
Range on HMM: 1-92/92
Sequence Identity: 24% (23 aa)

PIFSSELKKKEGPLEMWKTCRCELYKKSIVIKQGFSNPLIQNIDLSSKLEVNEIPSN-VRYQFSIKSHNS-TIYFLTENNNIFHQWVDAIRSILL
.| . .|.||.  .. || . . |  . ... .  .  .   |.||.  .| ..|.|  .. | |.. .  |.|| .|.   ...|..||.|.. 
VIKEGWLHKKG-KRKSWKKRWFVLFNNCLYYYKDDKYRPKGSIPLSDC-QVTKVPDNKRPHCFQIRT-DRRTYYFQAESEEEMNDWMQAIQSACR
Kinase 82699.m00089.AA AGC 120-374 28 5.5e-143 372.34 In-house 1-395 (395) Show / Hide 
Range on Protein: 120-374
Range on HMM: 1-395/395
Sequence Identity: 28% (112 aa)

FTIICTLGRGYFGKVLLCEHN------ITHDVYAIKTVKKAR---IMNEHKLHTIFAE------------RNILSVSH----------HPFIVT-MYFAF
| .. ..|.| |||| |....       | ..||.| .||..   |....... . .|            ||||.  .          |||||  ....|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTDKK--FYIGLEYVP---------GG-ALFRFLQ---IGRAMKISEVRFYVAE-------VALALDYLHS-KGILYRD-LKLENVLLCQDGHVKLTDFG
|....   |. .||.|         ||  ||  ||     . .  ...||| ||       ..|||.|||| .|| .|| ||.||.|| .|||.||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSKFVVEKG------------------------------------------------NYQQTSTFCG--TNEYLSPEMISDKPYGFEIDWWT--LGVFTY
|.| .. .|                                                . ..|.||||  | ||..||..    ||.. |||.  ||.. |
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EFLFTETPFYDKNLK----------KLYNNIL------TKEPRFP----------KDTPSVVKNFIRRLLNKEPSKRPT----------FEELKNDPFF
|.|.  .|||..|            .....|.      .....||          .   .  |..|..||.|.|.||..          .||.|| |.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 82699.m00089.AA Akt 120-374 40 2.7e-107 344.07 In-house 1-264 (264) Show / Hide 
Range on Protein: 120-374
Range on HMM: 1-264/264
Sequence Identity: 40% (107 aa)

FTIICTLGRGYFGKVLLCEHNITHDVY-AIKTVKKARIMNEHKLHTIFAERNILSVSHHPFIVTMYFAFQTDKKFYIGLEYVPGGALFRFLQIGRAMKIS
|...  ||.| ||||.|.. . | ..| |.|  || .| .  ..  ...|||||    ||||| ....||| .| |. ..|..|| ||  ||  | .. .
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

EVRFYVAEVALALDYLHSKGILYRD-LKLENVLLCQDGHVKLTDFGLSKFVVEKGNYQQTSTFCGTNEYLSPEMISDKPYGFEIDWWT-LGVFTYEFLFT
. |||.||. ||...||||.| ||| ||.||.|. .|||..||||||.|  . | . . | ||||| |||.||..... ..   |||. ||...||... 
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDH-DKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCG

ETPFYDKNLKKLYNNILTKEPRFP--KDTPSVVKNFIRRLLNKEPSKRP-----TFEELKNDPFF
  |||... .... .|.... .||  .      |..|..|||| |.||.     . .|.|..|.|
RPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 82699.m00089.AA SGK 120-374 37 7.69999999999e-101 312.17 In-house 1-283 (283) Show / Hide 
Range on Protein: 120-374
Range on HMM: 1-283/283
Sequence Identity: 37% (108 aa)

FTIICTLGRGYFGKVLLCEHNIT------------------HDVYAIKTVKKARIM-------NEHKLHTIFAER-NILSVSHHPFIVTMYFAFQTDKKF
| .. ..| | ||||.. .|  .                   ..||.|  .|. |        .  .   | ||| .||.   |||||   .||||..| 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YIGLEYVPGGALFRFLQIGRAMKISEVRFYVAEVALALDYLHSKGILYRDLKLENVLLCQDGHVKLTDFGLSKFVVEKGNYQQTSTFCGTNEYLSPEMIS
|  ..|| || .| .||  .  . ...|||.||...||.||||. | ||||| ||.||  .||..||||||.|  ... .   |.||||| ||| ||.. 
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTND--TTFTFCGTPEYLAPEVLR

DKPYGFEIDWWTLGVFTYEFLFTETPFYDKNLKKLYNNILTKEPRFPKDTPSVVKNFIRRLLNKEPSKR----PTFEELKNDPFF
 .|.. . ||| || . ||...   |||..| . .| ||. .. ..|.   .  .  |  ||.|.|.||      |.| || |||
KQPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 82699.m00089.AA AktR 120-374 40 2.7e-98 332.85 In-house 1-268 (268) Show / Hide 
Range on Protein: 120-374
Range on HMM: 1-268/268
Sequence Identity: 40% (110 aa)

FTIICTLGRGYFGKVLLCEHN-ITHDVYAIKTVKKARIMNEHKLHTIFAERNILS-VSHHPFIVTMYFAFQTDKKFYIGLEYVPGGALFRFLQIGRAMKI
|...  ||.| |||| |....  . ..||.| .||  | .. . | .  ||||.   . ||||| ....|||..| .. .||.||| ||. |.  . .. 
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

SEVRFYVAEVALALDYLHSK-GILYRDLKLENVLLCQDGHVKLTDFGLSK--FVVEKGNYQQTSTFCGTNEYLSPEMISD-KPYGFEIDWWTLGVFTYEF
...||| |.. |||.|||..  | ||||| || || .|||||.|||||||  |. .  . . . .||||.||..||||   |.... .|||..|.| || 
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMH--YDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEM

LFTETPFYDKNLKKLYNNILTKE---PRFPKDTPSVVKNFIR-RLLNKEPSKRPT-----FEELKNDPFF
..  .|||.|| . .. .|..|.   . .|..  |  |..|  .||.| | ||..     .||.|. |.|
VTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 82699.m00089.AA S_TKc 120-374 33 1.3e-96 328.18 SMART 1-231 (231) Show / Hide 
Range on Protein: 120-374
Range on HMM: 1-231/231
Sequence Identity: 33% (91 aa)

FTIICTLGRGYFGKVLLCEHNITHDVYAIKTVKKARIMNEHKLHTIFAERNILSVSHHPFIVTMYFAFQTDKKFYIGLEYVPG--GALFRFLQIGRA---
..|. ..|.| |||| .| |. |. ..||| .|           .|  |..||.  |||.||..| .||. ...|. .||..|  | ||....  .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---MKISEVRFYVAEVALALDYLHSKGILYRDLKLENVLLCQDGHVKLTDFGLSKFVVEKGNYQQTSTFCGTNEYLSPEMISDKPYGF-EIDWWTLGVFT
   .   ..|||......||.|.||.||..|||| ||.||..  |.|..||||....         .||||| .|..||..   .||. ..||| .|.  
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

YEFLFTETPFYDKNLKKLYNNILTKEPRFPKDTPSVVKNFIRRLLNKEPSKRPTFEELKN-------DPFF
||.|  ..||.  ........|.          .. .|.|||..|.|.|.||||  |. .       .|.|
YEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 82699.m00089.AA RSK-Unclassified 120-374 37 6.7e-91 285.73 In-house 1-283 (283) Show / Hide 
Range on Protein: 120-374
Range on HMM: 1-283/283
Sequence Identity: 37% (106 aa)

FTIICTLGRGYFGKVLLCEHNITHDVYAIKTVKKARIMNEHKLHTIFAERNILSVSHHPFIVTMYFAFQTDKKFYIGLEYVPGGALFRFLQIGRAMKISE
|  .  .|.| |||| | .   |  .||.|  .| ...   |   .  |.||.... ||||||.|..|||  . |  .|| .|| .|| ||  .  ...|
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

--VRFYVAEVALALDYLHSKGILYRDLKLENVLLCQDGHVKLTDFGLSKFV------VEK-------------GNYQQTSTFCGTNEYLSPEMISDKPYG
  ||||..|| .|| ||| ... ||||| .|..| |.|||.||||.||.        | |                  |  |||| ||| ||||     .
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGHT

FEIDWWTLGVFTYEFLFTETPFYDKNLKKLYNNILTKEPRFP--KDTPSVVKNFIRRLLNKEPSKR----PT-FEELKNDPFF
  .||||||.  || ||  .|.|  |   ...||.... .||  .      .  |..||.. |.||        .. |  |||
KAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF
Kinase 82699.m00089.AA Pkinase 120-374 29 2.8e-86 297.72 Pfam 1-293 (293) Show / Hide 
Range on Protein: 120-374
Range on HMM: 1-293/293
Sequence Identity: 29% (87 aa)

FTIICTLGRGYFGKVLLCEHNITHDVYAIKTVKKARIMNEHKLHTIF-AERNILSVSHHPFIVTMYFAFQTDKKFYIGLEYVPGG----ALFRFLQ--IG
..|. ..|.| ||.| .| |  | ...|.|..|| ..  . . . .  .|  |.   .||.||..| .|..... |. .||..||     ||....   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RAM--KISEVRFYVAEVALALDYLHSKGILYRDLKLENVLLCQDGHV----KLTDFGLSKFVVEKGNYQQTSTFCGTNEYLSPEMIS-DKPYGFEIDWWT
...     |..||. ... .|.|.||.||..||||.||.|. ..||.    |..||||.|..    |.. ..||||| .|..|| |  ...|| ..|.| 
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGVFTYEFLFTETPFYDK------NLKKLYNNILTKEPRFPKDTP---------------------SVVKNFIRRLLNKEPSKRPTFEELKNDPFF
.|.  ||.|. ..||...      . ......|. ....|. ...                     .  | ||...|.| |.||||.|.....|.|
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 82699.m00089.AA RSK 123-374 38 2.8e-85 289.63 In-house 1-278 (278) Show / Hide 
Range on Protein: 123-374
Range on HMM: 1-278/278
Sequence Identity: 38% (107 aa)

ICTLGRGYFGKVLLCEHNI---THDVYAIKTVKKARIMNEHK-LHTIFAERNILSVSH-HPFIVTMYFAFQTDKKFYIGLEYVPGGALFRFLQIGRA---
.  ||.| .||| ||   .   |  .|| | .||| |..  | . . ..|||||. .  |||||| . ||||..|.|. .||..|| ||. ||  .    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

MKISEVRFYVAEVALALDYLHSKGILYRDLKLENVLLCQ---DGHVKLTDFGLSKF-VVEKGNYQQTSTFCGTNEYLSPEMIS----DKPYGFEIDWWTL
.  .|..|| ||..||...||..|| .||||.||.|. .   .||.||||||..|  . ...  |.| |||.| ||. |||.     .. ..   |||.|
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHN--QWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSL

GVFTYEFLFTETPFYD---KNLKKLYNNILTKE--PRFP--KDTPSVVKNFIRRLLNKEPSKRPT-----FEELKNDPFF
||  || |.  .||.    .| |.. ..|....  ...|  .      |..||..| ..|.||..      ||.|..|.|
GVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 82699.m00089.AA PKC 120-374 36 8.6e-85 274.76 In-house 1-262 (262) Show / Hide 
Range on Protein: 120-374
Range on HMM: 1-262/262
Sequence Identity: 36% (97 aa)

FTIICTLGRGYFGKVLLCEHNITHDVYAIKTVKKARIMNEHKLHTIFAERNILSV-SHHPFIVTMYFAFQTDKKFYIGLEYVPGGALFRFLQIGRAMKIS
|. .  ||.| ||||.| |.  |  .|||| .||  |.  .      .|. .|.  . ||| . ..  |||  . .  .||| || |    |  |  | .
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

EVRFYVAEVALALDYLHSKGILYRDLKLENVLLCQDGHVKLTDFGLSKFVVEKGNYQQTSTFCGTNEYLSPEMISDKPYGFEIDWWTLGVFTYEFLFTET
  ||| ||...|| .||.||| ||||||.|||| ..||.|..|||..|  . .|  . ||||||| .|..|| .. ..||. .||| .||  ||..    
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNG--DTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQS

PFYDKNLKKLYNNILTKEPRFPKDTPSVVKNFIRRLLNKEPSKRPTF--------EELKNDPFF
||  ..   | ..|....|..|..     .. .  ...|.|.||           .. .  |||
PFHGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase 82699.m00089.AA MAST 120-374 29 1.3e-84 272.65 In-house 1-334 (334) Show / Hide 
Range on Protein: 120-374
Range on HMM: 1-334/334
Sequence Identity: 29% (97 aa)

FTIICTLGRGYFGKVLLCEHNITHDVYAIKTVKKARIMNEHKLHTIFAERNILSVSHHPFIVTMYFAFQTDKKFYIGLEYVPGGALFRFLQIGRAMKISE
|..|  ...| .||| | .|. | | .|.|..||.  .| . ... ..|||||...  ||.| |. .|||... .. .||. || ..  |..  ..  . 
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

VRFYVAEVALALDYLHSKGILYRDLKLENVLLCQDGHVKLTDFGLSKF-------VVEKG-------------------NYQQTST--------------
...|.||..|.|.||||.||  |||| .|.|.  .||.|||||||||.       ....|                   .|.|. .              
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDDLNMMYEGYTPPNIFNNSTDPMNKNQQDYSQFPGDFGINGNTNKNQIQ

-----------------------FCGTNEYLSPEMISDKP-YGFEIDWWTLGVFTYEFLFTETPFYDKNLKKLYNNILTKE---PRFPKD--------TP
                        ||| .|..|| | ... .|  .||| .|.  ||||   .|| |..  ....||| ..     .| .         .
QQQEQPQCQQQNMRPHNIHQNKQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMS

SVVKNFIRRLLNKEPSKRPTFE----ELKNDPFF
....  |..||.  |.||...     | |. |||
PEAQDLIEKLLQPDPRKRLGANNGADEVKQHPFF
Kinase 82699.m00089.AA Ciliate-E2-Unclassified 120-374 28 2.1e-83 283.37 In-house 1-352 (352) Show / Hide 
Range on Protein: 120-374
Range on HMM: 1-352/352
Sequence Identity: 28% (101 aa)

FTIICTLGRGYFGKVLLCEHNITHDVYAIKTVKKARIMNEHKLHT---------IFAERN-------------ILSVSHHPFIVTMYFAFQTDKKFYIGL
..|| ..|.| |||| .|.|. .  .||.|. ||..| . ..  .         .  ...             ||. . ||||| |...||.....|| .
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYVPGGALFRFLQI-----------------GRAMKISEVR-----FYVAEVALALDYLHSKG-ILYRDLKLENVLLCQDG---HVKLTDFGLSK---FV
||..|| |. ....                 ..     ...     || |.. ..|.|||.|. |..||.|.||.|. ..|   ..|..|||.||     
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

VEKGNYQQ-----------TSTFCGTNEYL----SPEMISDKPYG----FEIDWWTLGVFTYEFLFTETPFYDKNLKK----------------LYNNIL
...  ..|           ..|||||..|.    .||..  . |.    ...|.|.|||  ||.|| . ||||.| ..                ||.||.
NNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

TKEPRFPK--------DTPSVVKNFIR----RLLNKEPSKRPTFEELKNDPFF
 |.. |||        . .  .|.||.    ..|.| |.||.|||...| |.|
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 82699.m00089.AA Ciliate-E2 120-374 25 3.2e-81 276.13 In-house 1-365 (365) Show / Hide 
Range on Protein: 120-374
Range on HMM: 1-365/365
Sequence Identity: 25% (95 aa)

FTIICTLGRGYFGKVLLCEHNITHD-----------------------VYAIKTVKKARIMNEHKLHTIF----------AERNILSVSHHPFIVTMYFA
. .|  .|.| ||.| .|..  .                          ||.|..||  | .  .   |.           |.|||.   ||.|. || .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--TDKKFYIGLEYVPGGALFRFLQIGR-----------AMKISEVR---------------FYVAEVALALDYLHSKG-ILYRDLKLENVLLCQDGHV
||  .|...|. .||. || || .... .            ... |..               ||.|.. ||| |||||. |..||.|.||.|.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLTDFGLSKFVVEKGNY-----------------------------QQTSTFCGTNEYLSPEMISDKP---------YGFEIDWWTLGVFTYEFLFTETP
|..||||||.. .. ..                             ... |.||| .|..||... |.         |....|.| |||  ||.|| ..|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FYDKNLKKLYNNILTKEPRFP------------------KDTPSVVKNFIRR----LLNKEPSKRPT-FEELKNDPFF
|        ...|. .. .||                  |. .  .|..|..    .|.|.|.||.| .|...| |.|
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 82699.m00089.AA Pkinase_Tyr 120-278 26 6.2e-19 64.74 Pfam 1-172 (270) Show / Hide 
Range on Protein: 120-278
Range on HMM: 1-172/270
Sequence Identity: 26% (46 aa)

FTIICTLGRGYFGKVLLCEHN-----ITHDVYAIKTVKKARIMNEH-KLHTIFAERNILSVS-HHPFIVTMYFAFQ-TDKK--FYIGLEYVPGGALFRFL
 |.. .||.| ||.| ... .      . .| |.|.. |   | |. ..   ..| .|..   ||| || .| .    ..    || .||.|.| |  .|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPV-AVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

QI----GRAMKISEVRFYVAEVALALDYLHSKGILYRDLKLENVLLCQDGHVKLTDFGLSKFVVEKGNY-QQTS
.     ... ....   . ...| ...||.||..  |||   |.|.  ...|| .||||.. . ....| ....
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRG
Kinase 82699.m00089.AA TyrKc 120-372 21 7.1e-18 66.27 SMART 1-280 (280) Show / Hide 
Range on Protein: 120-372
Range on HMM: 1-280/280
Sequence Identity: 21% (63 aa)

FTIICTLGRGYFGKVLLCEHNITHDVYAIKTVKKARIMNEHKLHTIFAERNILSVS--HHPFIVTMYFAFQTD-------KKFYIGLEYVPGGALFRFLQ
 | . .||.| ||.| ... .      |.|..|.        .  .  | .|..    ||| || .| .  ..       .  .| .||.|.|.|  .|.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

IGRA-MKISEVRFYVAEVALALDYLHSKGILYRDLKLENVLLCQDGHVKLTDFGLSKFVVEK------GNYQQTSTFCGTNE-----YLSPEMISDKPYG
  |   . ..   .   .|   .|||||..  |||   |.|.  ...|| .|||||... ..      . |  ...  |..       ..|| | .. . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

FEIDWWTLGVFTYEFL-FTETPFYD-----KNLKKLYNNILTK-EPRFPKD--------TPSVVKNFIRRLLNKEPSKRPTFEELKNDP
.. | |  ||  .| . . ..| ..     .. . ..... .   .. |..         |. . . ...  . .|..||||.|.. . 
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 82699.m00089.AA S_TK_X 375-433 22 5.3e-07 30.5 SMART 1-79 (79) Show / Hide 
Range on Protein: 375-433
Range on HMM: 1-79/79
Sequence Identity: 22% (18 aa)

DNINWDDVYN--KRLKPPYIPKQV----TGRRATNFG---EKNRKDRTDSDATSVENTSE-----------FDGFSYAG
..|.||..||  |...||..||        . . ||    ...  . |. | .....  .           | ||.|  
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase 82699.m00089.AA Pkinase_Tyr 356-371 37 1.750728 2.26 Pfam 254-269 (270) Show / Hide 
Range on Protein: 356-371
Range on HMM: 254-269/270
Sequence Identity: 37% (6 aa)

NKEPSKRPTFEELKND
...|..||||.|. ..
HYDPEDRPTFSEIHEQ