Gene 92286.m00083 (T.vaginalis)

92286.m00083

Species: T.vaginalis
Alias: TvagK0415, 92286.m00083
External Links:
Annotation:

Classification

Group: AGC
Family: MAST
Subfamily: MAST

Sequence

Name Sequence Type Origin Length Description Download
92286.m00083.AA Protein None 696 None Fasta, JSON
92286.m00083.kin_dom Protein Kinase Domain None 258 None Fasta, JSON

Protein domain

Protein domains of 92286.m00083.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 92286.m00083.AA AGC 276-533 28 1.2e-133 347.63 In-house 1-395 (395) Show / Hide 
Range on Protein: 276-533
Range on HMM: 1-395/395
Sequence Identity: 28% (114 aa)

FTFLKRISGGAYARVFLAKKT------QTGDIYAVKVLKRRS-IQRKN--QVQRVLTE------------RDILHDCI----------SPYVVS-FYYSI
| ||| |. |.. .|.|..|       .||..||.|||| .  |..|.  .|....||            |.||  |           .|..|.  .|| 
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

TGVNN--LYLFMEYLP---------GG-DLYSLLE---QVGALDESSARFYIKQ-------IIEALQFLHE-HGIIHRD-LKPDNLLITADGMLKLTDFG
   ..  ||. |||.|         || .|.. |    . | .||. ||||. .       |. ||..||. .|||||| |||.|.|...|| .||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSYAGAVGR------------------------------------------------QISSDERIIG--TPDYVSPEVILCQSHGPTTDYWS--LGCIAY
|.  |  ..                                                .      . |  ||.|..||..    .|.. |.||  |||. |
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

ELISGIPPFHRDT----------ESMTLEAVI------TGRYEPI----------EDCSPELNDFITRLLDPDPERRLGAK-------GIEELKNHPWI
|...|.|||. |.          .  . . ..      . . .            .  |||. |.|..|| .|||.|||..       |.||.||||| 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 92286.m00083.AA S_TKc 276-533 33 1.6e-98 334.57 SMART 1-231 (231) Show / Hide 
Range on Protein: 276-533
Range on HMM: 1-231/231
Sequence Identity: 33% (91 aa)

FTFLKRISGGAYARVFLAKKTQTGDIYAVKVLKRRSIQRKNQVQRVLTERDILHDCISPYVVSFYYSITGVNNLYLFMEYLPG--GDLYSLLEQVGA---
...|. |  ||...|...... || |.|.|..|          .... |..||.    |..| .|...   ..||..|||..|  |||...... |    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LDESSARFYIKQIIEALQFLHEHGIIHRDLKPDNLLITADGMLKLTDFGLSYAGAVGRQISSDERIIGTPDYVSPEVILCQSHGP-TTDYWSLGCIA
   ..|  ||||..||..||...|.||||||||||.|.|..    .|..||||.              ..|||.|..|||.   ..|.   | ||.||| 
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

YELISGIPPFHRDTESMTLEAVITGRYEPIEDCSPELNDFITRLLDPDPERRLGAKGIEE----LKNHPWI
||...| |||.  .. |... .           |||. ||| ..|. |||.|..|  . .     |.|||.
YEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 92286.m00083.AA AktR 276-533 35 6e-84 285.19 In-house 1-268 (268) Show / Hide 
Range on Protein: 276-533
Range on HMM: 1-268/268
Sequence Identity: 35% (96 aa)

FTFLKRISGGAYARVFLAKKT-QTGDIYAVKVLKRRSIQRKNQVQRVLTERDILHDCI-SPYVVSFYYSITGVNNLYLFMEYLPGGDLYSLLEQVGALDE
|...| .  ||...|.|..|  .....|| |..|   |...|| ....|||.|. .|.  |  | ..|..   ..|.. ||| |||.|.. | . . ..|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

SSARFYIKQIIEALQFLHEH-GIIHRDLKPDNLLITADGMLKLTDFGLSY--AGAVGRQISSDERIIGTPDYVSPEVILC-QSHGPTTDYWSLGCIAYEL
. ||||. ||. ||..||.|  || |||||.|.|.  || .|.||||||      . ...     . ||| |..||.|.  . |. . |.|..|.  ||.
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEK--AYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEM

ISGIPPFHR-DTESMTLEAVITG--RYEPIEDCSPELNDFIT-RLLDPDPERRLG--AKGIEELKNHPWI
..|.|||   ... | .   |    . .. .. |... |.|. .||. .|. |||  ..|.||.|.||| 
VTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 92286.m00083.AA Pkinase 276-533 28 1.2e-82 285.66 Pfam 1-293 (293) Show / Hide 
Range on Protein: 276-533
Range on HMM: 1-293/293
Sequence Identity: 28% (86 aa)

FTFLKRISGGAYARVFLAKKTQTGDIYAVKVLKRRSIQRKNQVQRVL-TERDILHDCISPYVVSFYYSITGVNNLYLFMEYLPGG----DLYSLLE--QV
......|  |....|.....  ||.|.|||..|.|..  . ...... .|  |.. . .|..| .|.. .  ...|. |||..||    ||.....  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GAL--DESSARFYIKQIIEALQFLHEHGIIHRDLKPDNLLITADGML----KLTDFGLSYAGAVGRQISSDERIIGTPDYVSPEVIL-CQSHGPTTDYWS
|..  .|  ..||..||...|...|..|||||||||.|.||  .| .    |..||||.         |    . |||.|..||||. .| .||  | ||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGCIAYELISGIPPFHRD------TESMTLEAVITGRYEPIEDCS---------------------PELNDFITRLLDPDPERRLGAKGIEELKNHPWI
.||| ||...| |||  .      ..   .. .  ....  .. .                     .|. |||...|..||..|..   .|....|||.
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT---AEQILQHPWF
Kinase 92286.m00083.AA CAMK 281-533 19 2e-78 252.13 In-house 1-425 (425) Show / Hide 
Range on Protein: 281-533
Range on HMM: 1-425/425
Sequence Identity: 19% (83 aa)

RISGGAYARVFLAKKTQTG------------DIYAVKVLKRRSIQ-------------------------RKNQVQRVLTERDILHDCI-------SPYV
 .  |... |.|.. ..|.              .|.|..... ..                         | .  ..|. | .|.  .         | .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VSFYY---------------SITG-----VNNLYLFM---EYLPGG----DLYSLLEQV---------------GALDESSARFYIKQIIEALQFLHEHG
...|                . .       ...|..|   || .||    ||.. . .                | ..|. ||.|..||..|....|.|.
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IIHRDLKPDNLLITAD-----------------GMLKLTDFGLS--YAG---------AVGRQISSDE------------RIIGTPDYVS-PEVILCQS-
|.||||||.|.|.. .                 . .|..|||..  . .           |..   ..               ||| |.. |||.. .. 
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGH

-------------HGPTTDYWSLGCIAYELISGIPPFHRD-------------TESMTLEAVITGRYE-PIED-----------------------CSPE
             .|| .| ||.|.| | . .| |||  |             ... ..| ...|.|. | .                        .|.|
CNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQE

LNDFITRLLDPDPERRLGAKGIEELKNHPWI
  |.| ..| .|||.|.    ||. .||||.
CKDLIRKMLQVDPEKRM---TIEQCLNHPWM
Kinase 92286.m00083.AA Ciliate-E2 276-533 22 2.3e-78 266.66 In-house 1-365 (365) Show / Hide 
Range on Protein: 276-533
Range on HMM: 1-365/365
Sequence Identity: 22% (86 aa)

FTFLKRISGGAYARVFLAKKTQTGD-----------------------IYAVKVLKRRSIQRKNQVQRVL----------TERDILHDCISPYVVSFYYS
. |.| |  |... |...|. ...                        |||.|..| . |. ..|.....           |. ||    .|... .|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

IT--GVNNLYLFMEYLPGGDLYSLLE------------QVGALDESSARFYIKQIIE---------------ALQFLHEHG-IIHRDLKPDNLLITADGM
      ||.|| |||. ||||.....            . . ..|  .....|||..               ||..||. . |||||.||.|.|.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

LKLTDFGLSY----------AGAVGRQISSDER---------------------IIGTPDYVSPEVILCQS---------HGPTTDYWSLGCIAYELISG
.|..|||||              .....  . .                     |.||| |..||..  ..         ..   |.||||.| ||...|
IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

IPPFHRDTESMTLEAVITGRYE------------------PIEDCSPELNDFITR----LLDPDPERRLGAKGIEELKNHPWI
 |||        ..  . . ..                    ...|.|  |.| .    .|. ||| |..  |.|...||||.
KPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT--GWEQILNHPWF
Kinase 92286.m00083.AA RSK 279-533 34 5e-77 262.21 In-house 1-278 (278) Show / Hide 
Range on Protein: 279-533
Range on HMM: 1-278/278
Sequence Identity: 34% (97 aa)

LKRISGGAYARVFLAKKT---QTGDIYAVKVLKRRSIQRKNQ-VQRVLTERDILHDCI-SPYVVSFYYSITGVNNLYLFMEYLPGGDLYSLLEQVGA---
||    |.|  ||| .|.   .|| |||.||||.. | ...  . ...|||.|| .|  .| .|. .|.      ||| |||..||.|.  |.. .    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LDESSARFYIKQIIEALQFLHEHGIIHRDLKPDNLLITA---DGMLKLTDFGLSYAG-AV-GRQISSDERIIGTPDYVSPEVIL---CQS-HGPTTDYWS
..|. |.||. .|. |...||..|||||||||.| | .    .| .||||||..  . .  . .  .    ..| .|. ||..     |. |.   |.||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMT---FCYTIEYMAPEMLKRANQQGGHDKACDWWS

LGCIAYELISGIPPFHR---DTESMTLEAVITGR--YEPI--EDCSPELNDFITRLLDPDPERRLG--AKGIEELKNHPWI
||.. ||. .| |||.    .. . ... . .|.   .    .  |.|  |.|...|  ||..|||   ...||.|.|||.
LGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 92286.m00083.AA MASTL 276-476 46 1.5e-75 257.29 In-house 1-205 (283) Show / Hide 
Range on Protein: 276-476
Range on HMM: 1-205/283
Sequence Identity: 46% (95 aa)

FTFLKRISGGAYARVFLA-KKTQTGDIYAVKVLKRRSIQRKNQVQRVLTERDILHDCISPYVVSFYYSITGVNNLYLFMEYLPGGDLYSLLEQVGALDES
|. .| || ||. .|.|  |  . . .|||||.|.  .  || .  | .||| |    |...|. |||.  ....|| |||. |||. |||   |  || 
FVIVKPISRGAFGKVYLGYKNQKGKKLYAVKVMKKADMINKNMTHQVQAERDALALSKSQFCVHLYYSLQSASYVYLVMEYMIGGDVKSLLHMYGYFDEE

SARFYIKQIIEALQFLHEHGIIHRDLKPDNLLITADGMLKLTDFGLSYAGAVGRQIS---SDERIIGTPDYVSPEVILCQSHGPTTDYWS-LGCIAYELI
 |..||  .. ||..|| |||||||.||||.||  .| .||||||||    . | |    | ..|.|||||  ||  . | ||.  |.|. ||   ||  
MAIKYISEMVMALDYLHRHGIIHRDIKPDNMLISNEGHIKLTDFGLSKV-TMNRDINARVSMMDILGTPDYLKPEQDYQQTHGQVVDWWASLGVCFYEFM

SGIPPF
 |||||
KGIPPF
Kinase 92286.m00083.AA MAST 276-421 49 1.6e-72 233.05 In-house 1-146 (334) Show / Hide 
Range on Protein: 276-421
Range on HMM: 1-146/334
Sequence Identity: 49% (72 aa)

FTFLKRISGGAYARVFLAKKTQTGDIYAVKVLKRRSIQRKNQVQRVLTERDILHDCISPYVVSFYYSITGVNNLYLFMEYLPGGDLYSLLEQVGALDESS
|.| | || ||| .|.|.|.  |.|..|.||.| .   .||.|. | .||.||    .|.||...||    |.|.. |||. |||. |||. .|..||. 
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

ARFYIKQIIEALQFLHEHGIIHRDLKPDNLLITADGMLKLTDFGLS
|..|| ... .|..||.|||.||||||||.||...|  ||||||||
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLS
Kinase 92286.m00083.AA MAST 276-421 46 1.1e-70 214.92 In-house 1-149 (337) Show / Hide 
Range on Protein: 276-421
Range on HMM: 1-149/337
Sequence Identity: 46% (69 aa)

FTFLKRISGGAYARVFLAKKTQTGDIYAVKVLKRRSIQRKNQVQRVLTERDILHDCISPYVVSFYYSITG--VNNLYLFMEYLPGGDLYSLLEQVG-ALD
| |.| || ||| .|.|.|.  |.|..| ||.. . . .||||. |  ||.||     |.||...||      . |.. |||. |||  |||. .| ...
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

ESSARFYIKQIIEALQFLHEHGIIHRDLKPDNLLITADGMLKLTDFGLS
|. |..|| ... .| .||..||.||||||||.||...| .||||||||
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLS
Kinase 92286.m00083.AA NDR 276-421 45 4.4e-70 215.15 In-house 1-151 (350) Show / Hide 
Range on Protein: 276-421
Range on HMM: 1-151/350
Sequence Identity: 45% (69 aa)

FTFLKRISGGAYARVFLAKKTQTGDIYAVKVLKRRSIQRKNQVQRVLTERDILHDCI--SPYVVSFYYSITGVNNLYLFMEYLPGGDLYS---LLEQVGA
|...| |. ||. .|.|..|  ||.|||.|...   . .||||  |..||||.  .   .|.||. |||    ..||| |||.||||. .   || . . 
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI

LDESSARFYIKQIIEALQFLHEHGIIHRDLKPDNLLITADGMLKLTDFGLS
..|. |||||  ...|.  .|. |.||||.||||.|| .|| .|||||||.
FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLC
Kinase 92286.m00083.AA Akt 276-421 45 4e-62 197.34 In-house 1-148 (264) Show / Hide 
Range on Protein: 276-421
Range on HMM: 1-148/264
Sequence Identity: 45% (67 aa)

FTFLKRISGGAYARVFLAKKTQTGDIY-AVKVLKRRSIQRKNQVQRVLTERDILHDCISPYVVSFYYSITGVNNLYLFMEYLPGGDLYSLLEQVGALDES
|.||| .  |....|||.|| .|...| | |||| . |. ||||. ..||| ||  | .|..|. .||    ..||. |.| .||.|...| . .  .|.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

SARFYIKQIIEALQFLHEHGIIHRD-LKPDNLLITADGMLKLTDFGLS
 ||||. .|| |...||...|| || ||| |.|. .|| ..||||||.
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLC
Kinase 92286.m00083.AA MAST 430-533 41 2.2e-41 123.74 In-house 222-337 (337) Show / Hide 
Range on Protein: 430-533
Range on HMM: 222-337/337
Sequence Identity: 41% (48 aa)

ISSDERIIGTPDYVSPEVILCQS-HGPTTDYWSLGCIAYELISGIPPFHRDTES-MTLEAVIT--GRYEPIED--------CSPELNDFITRLLDPDPER
|  . ...||||| .||||| |. .|.. |.||.| | ||...|.|||  ||   |. . .|    . | .|.         |||  | | .||.|.|  
IHQNKQCCGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKK

RLGAKGIEELKNHPWI
||||.| .| |.||  
RLGANGADEIKQHPFF
Kinase 92286.m00083.AA MAST 429-533 40 6.3e-38 119.61 In-house 217-334 (334) Show / Hide 
Range on Protein: 429-533
Range on HMM: 217-334/334
Sequence Identity: 40% (48 aa)

QISSDERIIGTPDYVSPEVILCQS-HGPTTDYWSLGCIAYELISGIPPFHRDTESMTLEAVITGR------YEP-----IEDCSPELNDFITRLLDPDPE
.|  .....||||| .||||| |. ||.. |.||.| | ||.. |.|||  ||  .. . ..  .      .|.      |  |||  | | .||.|||.
NIHQNKQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPR

RRLGAK-GIEELKNHPWI
 ||||. | .| |.|| .
KRLGANNGADEVKQHPFF
Kinase 92286.m00083.AA NDR 435-533 39 6.2e-36 107.85 In-house 240-350 (350) Show / Hide 
Range on Protein: 435-533
Range on HMM: 240-350/350
Sequence Identity: 39% (44 aa)

RIIGTPDYVSPEVILC-QSHGPTTDYWSLGCIAYELISGIPPFHRDTESMTLEAVITGRYEPI-----EDC-----SPELNDFITRLLDPDPERRLGA--
...|||||  |||..  . ...| |.|||||| ||.. |.|||. ||   | . ..  . .       ..      |||  | |.||. |||..|||.  
STVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWK-QTWDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHG

KGIEELKNHPWI
||..| |.||. 
KGVDEIKSHPFF
Kinase 92286.m00083.AA Akt 438-533 36 5e-25 76.88 In-house 164-264 (264) Show / Hide 
Range on Protein: 438-533
Range on HMM: 164-264/264
Sequence Identity: 36% (37 aa)

GTPDYVSPEVILCQSHGPTTDYWS-LGCIAYELISGIPPF-HRDTESMTLEAVITGRYEPI--EDCSPELNDFITRLLDPDPERRLG--AKGIEELKNHP
||| | .||... . |. ..| |. |||. ||.. | ||| ..| . |  .   .. ..    .  |||  |.|..||  ||..|||   ....|.|.||
GTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYNQDHHQMF-KKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHP

WI
| 
WF
Kinase 92286.m00083.AA TyrKc 276-528 23 2.9e-15 24.22 SMART 1-280 (280) Show / Hide 
Range on Protein: 276-528
Range on HMM: 1-280/280
Sequence Identity: 23% (69 aa)

FTFLKRISGGAYARVFLAKKTQTGDIYAVKVLKRRSIQRKNQVQRVLTERDILHDC--ISPYVVSFYYSITGV-------NNLYLFMEYLPGGDLYSLLE
 |..| .  ||. .|.... .      |||.||  .      ..  . |  |..      | .| .|  .|           |.. ||| |.||| . | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

QVGA-LDESSARFYIKQIIEALQFLHEHGIIHRDLKPDNLLITADGMLKLTDFGLSYAGAVGRQISSD-------ERII-----GTPD-----YVSPEVI
  .  |  .    .  || .  ..||....|||||   | |.....  | .|||||      | | .|       . .      |. .       .||.|
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLS------RDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

LCQSHGPTTDYWSLGCIAYELIS-GIPPFHR-----DTESMTLEAVITG-RYEPIED--------CSPELNDFITRLLDPDPERRLGAKGIEELK
      . .| || |   .|. . | .|         . .  .| | .| | .. ..        |..|. . ...  . ||| |   . | |. 
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 92286.m00083.AA Pkinase_Tyr 276-421 28 2e-13 46.11 Pfam 1-158 (270) Show / Hide 
Range on Protein: 276-421
Range on HMM: 1-158/270
Sequence Identity: 28% (45 aa)

FTFLKRISGGAYARVFLAKKT----QTGDIYAVKVLKRRSIQRKNQVQRVLTERDILHDC-ISPYVVSFYYSIT-GVNN--LYLFMEYLPGGDLYSLLEQ
 ||.| .  ||. .|.... .    .|.   |||.||  . .. |  .  . |  |..     | .|..|  .|       .|. ||| |.|||.. | .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

----VGALDESSARFYIKQIIEALQFLHEHGIIHRDLKPDNLLITADGMLKLTDFGLS
     ..|. .    .  || .....|.....|||||   | |.| ..  | .||||.
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA