Gene 84270.m00645 (T.vaginalis)
84270.m00645
Species: T.vaginalis
Alias: TvagK0913, 84270.m00645
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| 84270.m00645.AA | Protein | None | 350 | None | Fasta, JSON |
| 84270.m00645.kin_dom | Protein Kinase Domain | None | 246 | None | Fasta, JSON |
Protein domains of 84270.m00645.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 84270.m00645.AA | CAMKL | 186-248 | 28 | 3.1e-15 | 44.91 | In-house | 216-285 (297) | Show / Hide |
Range on Protein: 186-248 Range on HMM: 216-285/297 Sequence Identity: 28% (21 aa) KSDIWSLGILLWFMVTKKLPWN-------INNVVVMLKQIQKGTPDNIN---MLPVEFRDIIFSTLVLNPEKR | ||||.|..| .||. .||.. ... . |. ..... ... .. . ||.| . |. ||||| KVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKR |
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| Kinase | 84270.m00645.AA | MARK | 186-248 | 36 | 6.2e-14 | 42.1 | In-house | 186-250 (262) | Show / Hide |
Range on Protein: 186-248 Range on HMM: 186-250/262 Sequence Identity: 36% (24 aa) KSDIWSLGILLWFMVTKKLPWN--INNVVVMLKQIQKGTPDNINMLPVEFRDIIFSTLVLNPEKR | ||||||..| |||. ..|. .. . . |.|..| .| ....| |..| . |..|||.| KVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEER |
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| Kinase | 84270.m00645.AA | Ciliate-E2 | 170-248 | 23 | 1.5e-11 | 35.92 | In-house | 252-352 (365) | Show / Hide |
Range on Protein: 170-248 Range on HMM: 252-352/365 Sequence Identity: 23% (26 aa) GFLSPEYLT--------AGSFPTIKSDIWSLGILLWFMVTKKLPWNINNVVVMLKQIQKGTPD------------------NINMLPVEFRDIIFS---- |...|| | .. . |.||||||..| .|...|.|. ..||... | . . .. | |.| GYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKR TLVLNPEKR |. .|||| MLQKDPEKR |
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| Kinase | 84270.m00645.AA | CAMK | 186-248 | 21 | 1.4e-10 | 29.58 | In-house | 314-413 (425) | Show / Hide |
Range on Protein: 186-248 Range on HMM: 314-413/425 Sequence Identity: 21% (21 aa) KSDIWSLGILLWFMVTKKLPWNIN-------------NVVVMLKQIQKGTPD-NINMLPV-----------------------EFRDIIFSTLVLNPEKR |.|.||.|..| .|.. ..|.. | ....|.|| | ... | .| | . |. .|||| KCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKR |
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| Kinase | 84270.m00645.AA | MELK | 174-261 | 28 | 1.6e-10 | 31.85 | In-house | 168-254 (254) | Show / Hide |
Range on Protein: 174-261 Range on HMM: 168-254/254 Sequence Identity: 28% (25 aa) PEYLTAGSFPTIKSDIWSLGILLWFMVTKKLPWNINNVVVMLKQIQKGTPDNINMLPVEFRDIIFSTLVLNPEKRTDTQTLVHARPGV || . .. |.||.||||. .. ||.. |. .| |.|..| . . | .| .... | .|.|| . |.. | | PELIQGKQYIGSEADVWSMGILLYVLMCGFLPFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLN-HPWV |
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| Kinase | 84270.m00645.AA | GIN4 | 173-261 | 29 | 1.8e-10 | 29.22 | In-house | 202-293 (293) | Show / Hide |
Range on Protein: 173-261 Range on HMM: 202-293/293 Sequence Identity: 29% (27 aa) SPEYLTAGSFPTIKSDIWSLGILLWFMVTKKLPWNIN--NVVVMLKQIQKGTPDNINM--LPVEFRDIIFSTLVLNPEKRTDTQTLVHARPGV .|| . ||.|| |..|. ..| .||.. . |. .| ..||| . . . | .|.| ||. |||| |. ... | . APEIVMGIPYHGFASDVWSCGVILFALLTGHLPFDEEDGNIRKLLLKVQKGKYEMPSDDEISREAQDLIRKILVVDPEKRIKTRDILK-HPLI |
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| Kinase | 84270.m00645.AA | AGC | 171-248 | 22 | 4.5e-10 | 20.72 | In-house | 273-373 (395) | Show / Hide |
Range on Protein: 171-248 Range on HMM: 273-373/395 Sequence Identity: 22% (24 aa) FLSPEYLTAGSFPTIKSDIWS--LGILLWFMVTKKLPWNINNVV----------VMLKQIQKGT---PDNINM-------------LPVEFRDIIFSTLV ...|| | . |.|| ||.|. |.| . | . .|.. | ..|..| .... . . .| .|.| |. YMAPEIL-----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLC LNPEKR .|||| KDPEKR |
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| Kinase | 84270.m00645.AA | S_TKc | 9-261 | 17 | 8.6e-10 | -33.33 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 9-261
Range on HMM: 1-231/231
Sequence Identity: 17% (48 aa)
FTFIKALNSGFLGPSYLLKKDDNNQQYICKSFMKSAIGDDADVDNFVQILKISHRLKESCFLPFHYIYVMDEYIYAVRPFFEG--LALSAYIANC-----
..... . .| | |. .. . .... .| .. . .|||| . ...... ...| | . .| | || ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL
---ESDINIAYAQWKVLCRLYRHLHKRKISPNFIKPSNIFMENGNIAFITD-----IYPPPRSFNPTIHRSNPFDV--GFLSPEYLTAGSFPTIKSDIWS
. ... . ..| | ..|...| .||.||.. . |.| .. . | . ...|| | .. . |.|.||
RFPFPE-HARFYMYQICCALE-YCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------TTFCGTPWYMAPEVL---GYGKCKCDWWS
LGILLWFMVTKKLPWNINNVVVMLKQIQKGTPDNINMLPVEFRDIIFSTLVLNPEKRTDTQTLVH------ARPGV
.|..|. |.. . |. .. .|.|.| . |..|.| |. .|||| . . . | .
CGCILYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
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| Kinase | 84270.m00645.AA | ULK | 184-248 | 23 | 4.7e-09 | 27.83 | In-house | 234-317 (329) | Show / Hide |
Range on Protein: 184-248 Range on HMM: 234-317/329 Sequence Identity: 23% (20 aa) TIKSDIWSLGILLWFMVTKKLP---WNINNVV-----VMLKQ-------IQKGTPD-----NINMLPVEFRDIIFSTLVLNPEKR . |.||||||... |.. | | | .| . ... |.| .. |.. . |..|.| |. ....| DYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDR |
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| Kinase | 84270.m00645.AA | Ciliate-E2-Unclassified | 132-248 | 19 | 5.8e-09 | 27.25 | In-house | 170-340 (352) | Show / Hide |
Range on Protein: 132-248 Range on HMM: 170-340/352 Sequence Identity: 19% (34 aa) IKPSNIFMENGN---IAFITD-----IYPPP---RSFN---------PTIHRSNPFDVGFL----SPEYLTAGSFPT---IKSDIWSLGILLWFMVTKKL |||.||.. |.. |.| | . . .| . . .. ... .||.| . .|.||||||..| .|.. .. IKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYY PWNINNVVV----------------MLKQIQKGTPDNINMLP--------VEFRDIIF----STLVLNPEKR | . || ....|... ... .. . | |.| . |. ||.|| PFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKR |
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| Kinase | 84270.m00645.AA | Pkinase | 170-248 | 18 | 1.1e-08 | 31.75 | Pfam | 176-281 (293) | Show / Hide |
Range on Protein: 170-248 Range on HMM: 176-281/293 Sequence Identity: 18% (20 aa) GFLSPEYLTAGSFPTIKSDIWSLGILLWFMVTKKLPWNIN------NVVVMLKQIQKGTPDNINMLP---------------------VEFRDIIFSTLV ....|| . |. . |.|.||.|..|. |.....|. . .|...| .. .. . |..|.| . | WYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLC LNPEKR ..|.|| KDPKKR |
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| Kinase | 84270.m00645.AA | Ciliate-E2b | 184-206 | 47 | 8.4e-08 | 19.96 | In-house | 188-210 (272) | Show / Hide |
Range on Protein: 184-206 Range on HMM: 188-210/272 Sequence Identity: 47% (11 aa) TIKSDIWSLGILLWFMVTKKLPW |.|.||||.|| |... ...|| TYKVDIWSVGICLYEFMCGYVPW |
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| Kinase | 84270.m00645.AA | Ciliate-E2b | 9-45 | 31 | 2.7e-05 | 12.25 | In-house | 1-38 (272) | Show / Hide |
Range on Protein: 9-45 Range on HMM: 1-38/272 Sequence Identity: 31% (12 aa) FTFIKALNSGFLGPSYLLKK-DDNNQQYICKSFMKSAI . .|| | .| |. || .. .. .|.| |.. |. | MIYIKKLGFGQFGSVYLVWNTKNTKQYYAMKCISKNQI |
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| Kinase | 84270.m00645.AA | TyrKc | 9-258 | 16 | 4.4e-05 | -140.43 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 9-258 Range on HMM: 1-280/280 Sequence Identity: 16% (49 aa) FTFIKALNSGFLGP--SYLLKKDDNNQQYICKSFMKSAIGDDADVDNFVQILKISHRL--KESCFLPFHYIYVMD-------EYIYAVRPFFEGLALSAY |..| | .|. | .| .| |. ..| . | . ..| ..| . . . .. . . . | .. | . .. .| | ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY IANCESDINIAYAQWKVLCRLY-------RHLHKRKISPNFI----KPSNIFMENGNIAFITD------IYPP------PRSFNP--TIHRSNPFDVGFL . ... . ..| |. ..||.. |.| |. ..... |.| || . . .. .. . . LRKHRPK-----LCMKDLLSFCWQIACGMEYLHSK----NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM SPEYLTAGSFPTIKSDIWSLGILLW--FMVTKKLPWN-----INNVVVMLKQIQKGTPDNINM--------LPVEFRDIIFSTLVLNPEKRTDTQTLVHA .|| . | | |.|||.|| |...| | .. ... ..| |. . | . .. | | .|. . .||.| ..... APECINYGKF-TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHEC R F |
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| Kinase | 84270.m00645.AA | Ciliate-E2-Unclassified | 9-43 | 20 | 0.000936 | 8.93 | In-house | 1-39 (352) | Show / Hide |
Range on Protein: 9-43 Range on HMM: 1-39/352 Sequence Identity: 20% (8 aa) FTFIKALNSGFLGPSYLLKKDDNNQQY-----ICKSFMKS ...|| ...| | |........ || ..|. ... YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYK |
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| Kinase | 84270.m00645.AA | ULK | 132-149 | 30 | 0.095456 | 1.98 | In-house | 156-185 (329) | Show / Hide |
Range on Protein: 132-149 Range on HMM: 156-185/329 Sequence Identity: 30% (9 aa) IKPSNIFMENGN------------IAFITD |||.|| . ||. .. |.| IKPQNILIHNGQPKTDSKKVHPNGVLKIAD |
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