Gene 84337.m00134 (T.vaginalis)

84337.m00134

Species: T.vaginalis
Alias: TvagK0914, 84337.m00134
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
84337.m00134.AA Protein None 351 None Fasta, JSON
84337.m00134.kin_dom Protein Kinase Domain None 266 None Fasta, JSON

Protein domain

Protein domains of 84337.m00134.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 84337.m00134.AA MARK 186-249 31 1e-15 48.03 In-house 185-250 (262) Show / Hide 
Range on Protein: 186-249
Range on HMM: 185-250/262
Sequence Identity: 31% (21 aa)

YKADIWSLGILLWFMTVKKLPWN--INNVVVMLKQIQKGSPENFAVLPVEIRDIVASMLVFNPEKR
.|.||||||..| ||.. ..|.    .. . . |.|..|... .  ...|.|... ..|..|||.|
PKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEER
Kinase 84337.m00134.AA CAMKL 186-249 27 1.9e-15 45.61 In-house 215-285 (297) Show / Hide 
Range on Protein: 186-249
Range on HMM: 215-285/297
Sequence Identity: 27% (20 aa)

YKADIWSLGILLWFMTVKKLPWN-------INNVVVMLKQIQKGSPENFA---VLPVEIRDIVASMLVFNPEKR
.|.||||.|..| .| . .||..       ... .  |. ....  ...     .. . ||.  .||. |||||
PKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKR
Kinase 84337.m00134.AA Ciliate-E2 133-249 18 1e-12 39.96 In-house 187-352 (365) Show / Hide 
Range on Protein: 133-249
Range on HMM: 187-352/365
Sequence Identity: 18% (35 aa)

IKPSNIFMENGSIAFITD---------------------IYPPPR---TFNPTIHRSNPFDVGFL------------SPEYLIP----GSF---------
|||.||..      .|.|                     .|.  .   .  |.. .        .            .|.|. |    |           
IKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMD--------QIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKG

PTYKADIWSLGILLWFMTVKKLPWNINNVVVMLKQIQKGSPE------------------NFAVLPVEIRDIVAS----MLVFNPEKR
 .||.||||||..| .|  .|.|.        ..||...  .                  ..  .. |  |.       ||. .||||
YDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKR
Kinase 84337.m00134.AA MELK 188-260 33 2.9e-12 37.88 In-house 181-254 (254) Show / Hide 
Range on Protein: 188-260
Range on HMM: 181-254/254
Sequence Identity: 33% (25 aa)

ADIWSLGILLWFMTVKKLPWNINNVVVMLKQIQKGSPENFAVLPVEIRDIVASMLVFNPEKRVD-SEVLVHSRP
||.||.||||. . .  ||..  |. .| |.|..|  |    | .| ....  ||  .|.||.   ..| |   
ADVWSMGILLYVLMCGFLPFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV
Kinase 84337.m00134.AA Ciliate-E2-Unclassified 10-249 17 5.1e-11 34.49 In-house 1-340 (352) Show / Hide 
Range on Protein: 10-249
Range on HMM: 1-340/352
Sequence Identity: 17% (59 aa)

FSFLKSLNSGFLGPSYLLKKNDNNKQY-----ICKGFIKSAIGDDADVDNFIQIIKISRKLKEACFLP------------------YHYFYIM--DQYIY
. ..| ...|  |  |........ ||     ..|  |..         ......|.  ..|.  .                    ...||.   .|.||
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIY

AVRPFFEGLDLSAYIANCAT-------------------DINIV-----YAQWKVLCRLYRHLHKRK-ISPNFIKPSNIFMENGS---IAFITD------
 |  ..||.||. || .. .                   . ...     .  . .|. |  .||. . |    |||.||.. |.       |.|      
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLE-YLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKK

IYPP---PRTFN--------PTIHRSNPFDVGFLS---PEYLIPGSFPT----YKADIWSLGILLWFMTVKKLPWNINNVVV----------------ML
.  .     |..        . .  ..    ....   .  .. |  .     ||.||||||..| .|   ..| . ||                   ..
YQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLY

KQIQKGSPENFA--------VLPVEIRDIVA----SMLVFNPEKR
..|... ....          .. |  |..     .||. ||.||
QNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKR
Kinase 84337.m00134.AA Ciliate-E2c 185-251 24 2.5e-10 32.49 In-house 197-300 (310) Show / Hide 
Range on Protein: 185-251
Range on HMM: 197-300/310
Sequence Identity: 24% (25 aa)

TYKADIWSLGILLWFMTVKKLPWN-----------------INNVVVMLKQIQK--------------------GSPENFAVLPVEIRDIVASMLVFNPE
|.|.||||||..| .|  .||||                  . | .. |||. .                    .....   .  |. .. . ||.. .|
TEKSDIWSLGVTLYYMLCYKLPWESIQEYDSHNICNHCYPWWQNTMKHLKQHIWEYFNPQASAAGVSPITQNIHFPENYEQNISQEVKQLIHKMLQVDEE

KRVD
|| |
KRID
Kinase 84337.m00134.AA AGC 172-249 21 4.2e-10 20.8 In-house 273-373 (395) Show / Hide 
Range on Protein: 172-249
Range on HMM: 273-373/395
Sequence Identity: 21% (23 aa)

FLSPEYLIPGSFPTYKADIWS--LGILLWFMTVKKLPWNINNVV----------VMLKQIQKG-----SPENF-----------AVLPVEIRDIVASMLV
...|| |      .. .|.||  ||.|.  | . . | . .|..           | ..|..|      .. |             . .| .|..  .|.
YMAPEIL-----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLC

FNPEKR
 .||||
KDPEKR
Kinase 84337.m00134.AA CAMK 185-249 19 4.6e-10 27.89 In-house 312-413 (425) Show / Hide 
Range on Protein: 185-249
Range on HMM: 312-413/425
Sequence Identity: 19% (20 aa)

TYKADIWSLGILLWFMTVKKLPWNIN-------------NVVVMLKQIQKGSPE-NFAVLPV-----------------------EIRDIVASMLVFNPE
..|.|.||.|..| .| . ..|..               |   ....|.||  .     ..                        | .| . .||. .||
GPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPE

KR
||
KR
Kinase 84337.m00134.AA S_TKc 10-260 18 7.2e-10 -32.18 SMART 1-231 (231) Show / Hide 
Range on Protein: 10-260
Range on HMM: 1-231/231
Sequence Identity: 18% (50 aa)

FSFLKSLNSGFLGPSYLLKKNDNNKQYICKGFIKSAIGDDADVDNFIQIIKISRKLKEACFLPYHYFYIMDQYIYAVRPFFEG--LDLSAYIANC-----
. .|. . .|  |  |. .... .... .|             ..... |.| .| .      .....   ...| |  . .|   ||  || ..     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---ATDINIVYAQWKVLCRLYRHLHKRKISPNFIKPSNIFMENGSIAFITD-----IYPPPRTFNPTIHRSNPFDV--GFLSPEYLIPGSFPTY-KADIW
    .   . .  . ..| |  ..|...|    .||.||.. .     |.|     ..             . | .   ...|| |      .. |.|.|
RFPFPE-HARFYMYQICCALE-YCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------TTFCGTPWYMAPEVL----GYGKCKCDWW

SLGILLWFMTVKKLPWNINNVVVMLKQIQKGSPENFAVLPVEIRDIVASMLVFNPEKRVDSEVLV-------HSRP
|.|..|. | . . |.   .. .|.|.|           . | .|..  .|...||||   |.|        |   
SCGCILYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
Kinase 84337.m00134.AA ULK 185-249 24 1.4e-09 29.65 In-house 234-317 (329) Show / Hide 
Range on Protein: 185-249
Range on HMM: 234-317/329
Sequence Identity: 24% (21 aa)

TYKADIWSLGILLWFMTVKKLP---WNINNVV-----VMLKQ-------IQKGSPE-----NFAVLPVEIRDIVASMLVFNPEKR
.||.||||||...  | . | |   | .|  .       ...       |.|  ..     |  ..  |..|.   ||......|
DYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDR
Kinase 84337.m00134.AA Pkinase 171-249 17 2.4e-08 30.6 Pfam 176-281 (293) Show / Hide 
Range on Protein: 171-249
Range on HMM: 176-281/293
Sequence Identity: 17% (19 aa)

GFLSPEYLIPGSFPTYKADIWSLGILLWFMTVKKLPWNIN------NVVVMLKQIQKGSPENFAVLP---------------------VEIRDIVASMLV
....|| .  |.  ..|.|.||.|..|. |  ...|.         .  .|...| .. ..     .                      | .|.. ..| 
WYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLC

FNPEKR
..|.||
KDPKKR
Kinase 84337.m00134.AA Ciliate-E2b 185-207 52 1e-07 19.71 In-house 188-210 (272) Show / Hide 
Range on Protein: 185-207
Range on HMM: 188-210/272
Sequence Identity: 52% (12 aa)

TYKADIWSLGILLWFMTVKKLPW
|||.||||.|| |... ....||
TYKVDIWSVGICLYEFMCGYVPW
Kinase 84337.m00134.AA TyrKc 10-259 15 0.000554 -158.23 SMART 1-280 (280) Show / Hide 
Range on Protein: 10-259
Range on HMM: 1-280/280
Sequence Identity: 15% (47 aa)

FSFLKSLNSGFLGP--SYLLKKNDNNKQYICKGFIKSAIGDDADVDNFIQIIKISRKL--KEACFLPYHYFYIMD-------QYIYAVRPFFEGLDLSAY
 ...| | .|. |      .|          .  .|.   |   .  |.. ..| .||  .  . .  .   . .       . .. |  . .. ||  |
ITLGKKLGEGAFGEVYKGTWK---------IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

IANCATDINIVYAQWKVLCRLY-------RHLHKRKISPNFI----KPSNIFMENGSIAFITD------IYPP------PRTFNP--TIHRSNPFDVGFL
. ..  .      ..| |.          ..||..    |.|       |.   .. .. |.|      ||          .  .  . ..  .. .  .
LRKHRPK-----LCMKDLLSFCWQIACGMEYLHSK----NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM

SPEYLIPGSFPTYKADIWSLGILLW--FMTVKKLPWN-----INNVVVMLKQIQKGSPENFAV--------LPVEIRDIVASMLVFNPEKRVDSEVLVHS
.|| .  | | | | |.|| |...|  |   .. ...     ..|  |. .  | . ..  .          | |. .|  .   ..||.|   . ... 
APECINYGKF-TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHEC

R
 
F
Kinase 84337.m00134.AA Ciliate-E2b 10-46 26 0.002233 6.31 In-house 1-38 (272) Show / Hide 
Range on Protein: 10-46
Range on HMM: 1-38/272
Sequence Identity: 26% (10 aa)

FSFLKSLNSGFLGPSYLLKK-NDNNKQYICKGFIKSAI
. . |.| .|  |. || .. .. ...|  | ..|. |
MIYIKKLGFGQFGSVYLVWNTKNTKQYYAMKCISKNQI