Gene 96997.m00086 (T.vaginalis)

96997.m00086

Species: T.vaginalis
Alias: 96997.m00086, TvagK0442
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
96997.m00086.AA Protein None 417 None Fasta, JSON
96997.m00086.kin_dom Protein Kinase Domain None 251 None Fasta, JSON

Protein domain

Protein domains of 96997.m00086.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH 96997.m00086.AA PH 3-98 19 2.7e-12 48.09 SMART 1-82 (82) Show / Hide 
Range on Protein: 3-98
Range on HMM: 1-82/82
Sequence Identity: 19% (19 aa)

TTIEGWLHKKDPENSLWHRRYCILTENKLMIQKSQGEDYENFVSLTGDVKVEIDDKKPPPRIHIITDKNEVITLSSPDEPVFNKWAFLIIGATMNR
...||||.||   .  |..|...|... |.. |.   ..  ...|..  .|.  .      . |.. .. ..... ..|  ...|   |  |. | 
VIKEGWLYKKS--K-RWKKRWFVLFNDCLYYYKDK--KPKGSIPLSDC-TVRE-P-----CFEIHH-DR-TYYFQCESEEEMQEWMQAIQKAIHNN
PH 96997.m00086.AA PH 3-87 23 4.7e-10 38.89 Pfam 1-83 (92) Show / Hide 
Range on Protein: 3-87
Range on HMM: 1-83/92
Sequence Identity: 23% (20 aa)

TTIEGWLHKKDPENSLWHRRYCILTENKLMIQKSQGEDYENFVSLTGDVKVEIDDKKPPPRIHIITDKNE-VITLSSPDEPVFNKW
 ..|||||||   .. |..|...|..|.|.. |. ....   ..| .  .|..... . | .  |.  .. ..... ..|  .| |
VIKEGWLHKKG-KRKSWKKRWFVLFNNCLYYYKDDKYRPKGSIPLSDC-QVTKVPDNKRPHCFQIRT-DRRTYYFQAESEEEMNDW
Kinase 96997.m00086.AA AGC 106-356 32 2.3e-174 455.35 In-house 1-395 (395) Show / Hide 
Range on Protein: 106-356
Range on HMM: 1-395/395
Sequence Identity: 32% (129 aa)

FRIISVLGRGYYGKVMLCEEN------TTKELYAIKTIHKKM-LVNSD--KVQNALTE------------RNVLVRVH----------HPFIVS-LKTTF
|... |.|.| .|||.|....      .|...||.| . ||   |  .  .|....||            ||.|....          |||||. |. .|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTPTK--LYFAMEYAP---------GG-ELFFHLE---RKGAFHIHDVRIYVAE-------LALAIEYLHD-NNIIYRD-IKPENILLDSEGHVKITDFG
|....  ||| |||.|         || |||.||    ..| |    .|.| ||       ..||.||||. ..||.|| .||||||||..||.|.||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSKEME----------------------------------------------------EDTTSTLCG--SPNYMAPEIITHTRYGPAVDWWS--LGILMY
|.||.                                                     .|.|.|.||  .|.||||||.    ||.|.||||  ||.|||
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMLFGVQPFVNEN----------KSVLLMMIA------TCRVSFP----------RNANPDAQSLILGLLQKNPSERFG----------FEQIKSHPFF
|||.|  || ..|          .  .   |       ...| ||          |.  |.|..|| .||.|.|..| |          .|.||.||.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 96997.m00086.AA Akt 106-356 46 1.9e-142 458.19 In-house 1-264 (264) Show / Hide 
Range on Protein: 106-356
Range on HMM: 1-264/264
Sequence Identity: 46% (122 aa)

FRIISVLGRGYYGKVMLCEENTTKELY-AIKTIHKKMLVNSDKVQNALTERNVLVRVHHPFIVSLKTTFQTPTKLYFAMEYAPGGELFFHLERKGAFHIH
|... |||.| .|||.|.... |...| |.| . |..... ..|....||||.|... |||||.|.  |||..|||| |.|..|||||.|| ||. |   
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

DVRIYVAELALAIEYLHDNNIIYRD-IKPENILLDSEGHVKITDFGLSKEM---EEDTTSTLCGSPNYMAPEIITHTRYGPAVDWWS-LGILMYEMLFGV
  | |.||. ||||.|| .||||||  ||||||.|..||...|||||.||.   . |.| |.||.| |.||||.  . .. |||||. ||..||||..| 
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

QPFVNENKSVLLMMIATCRVSFP--RNANPDAQSLILGLLQKNPSERFG-----FEQIKSHPFF
 || |... ..   | .. | ||  ..  |....|| |||.|.|..| |      ..||.||.|
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 96997.m00086.AA SGK 106-356 39 1.8e-132 411.64 In-house 1-283 (283) Show / Hide 
Range on Protein: 106-356
Range on HMM: 1-283/283
Sequence Identity: 39% (112 aa)

FRIISVLGRGYYGKVMLCEENTT------------------KELYAIKTIHKKMLV-------NSDKVQNALTER-NVLVRVHHPFIVSLKTTFQTPTKL
|....|.| | .|||.. .   .                  . .||.| . |.  .       .  .. . ..|| ..|. . |||||.|.  |||..||
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YFAMEYAPGGELFFHLERKGAFHIHDVRIYVAELALAIEYLHDNNIIYRDIKPENILLDSEGHVKITDFGLSK-EMEE-DTTSTLCGSPNYMAPEIITHT
|| |.|. |||.|.|| | . |  . .|.|.||...|.||||. .||||| ||||||||..||...|||||.| .... |||.| ||.| |.|||.. . 
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

RYGPAVDWWSLGILMYEMLFGVQPFVNENKSVLLMMIATCRVSFPRNANPDAQSLILGLLQKNPSERFGFE----QIKSHPFF
 .. .||||.||...|||..|  || . ||. .   |      .|..  .|| .|| |||||.|..| |      .||.||||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 96997.m00086.AA AktR 106-356 45 4e-124 418.65 In-house 1-268 (268) Show / Hide 
Range on Protein: 106-356
Range on HMM: 1-268/268
Sequence Identity: 45% (121 aa)

FRIISVLGRGYYGKVMLCEEN-TTKELYAIKTIHKKMLVNSDKVQNALTERNVLV-RVHHPFIVSLKTTFQTPTKLYFAMEYAPGGELFFHLERKGAFHI
|... .||.| .|||.|.... .....||.| |.|| ...  . . ..||||..   . ||||| |. .||| .||.|.||| ||||||.|| .|. |  
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

HDVRIYVAELALAIEYLHDN-NIIYRDIKPENILLDSEGHVKITDFGLSK---EM-EEDTTSTLCGSPNYMAPEIITH-TRYGPAVDWWSLGILMYEMLF
 ..|.| |.  ||.||||.. ||||||.||||||||..||||||||||||    | ..... ..||.| |||||.||    .. .||||..||. |||..
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GVQPFVNENKSVLLMMIATCR-VSFPRNANP--DAQSLIL-GLLQKNPSERFG-----FEQIKSHPFF
|  || ..|.  .. .| ... ..|| ....   ...||  .||.||| .| |     .|.|||||.|
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 96997.m00086.AA RSK 109-356 41 2.3e-115 389.57 In-house 1-278 (278) Show / Hide 
Range on Protein: 109-356
Range on HMM: 1-278/278
Sequence Identity: 41% (114 aa)

ISVLGRGYYGKVMLCEEN---TTKELYAIKTIHKKMLVNSDK-VQNALTERNVLVRVH-HPFIVSLKTTFQTPTKLYFAMEYAPGGELFFHLERKGA---
..|||.| |||| || .     |. .|| | ..|...|...| .  ..||||.| |.  |||||.|. .|||..|||  ||| .||||| ||....    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FHIHDVRIYVAELALAIEYLHDNNIIYRDIKPENILLDS---EGHVKITDFGLSKEM---EEDTTSTLCGSPNYMAPEIIT---HTR-YGPAVDWWSLGI
|  .....| ||..||.|.||.  ||.||.||||||.|.   |||.|.||||..|..   ..  | | |.. .|||||...   . . .. |.||||||.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LMYEMLFGVQPFVN---ENKSVLLMMIATCR--VSFP--RNANPDAQSLILGLLQKNPSERFG-----FEQIKSHPFF
||||||.|  || .   .|.....  | ...  ...|   .  ..|..|| ..|...|. | |      |.||.||.|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 96997.m00086.AA PKA 106-356 43 8.3e-112 377.75 In-house 1-263 (263) Show / Hide 
Range on Protein: 106-356
Range on HMM: 1-263/263
Sequence Identity: 43% (116 aa)

FRIISVLGRGYYGKVMLCEENTTKELYAIKTIHKKMLVNSDKVQNALTERNVLVRVHHPFIV-SLKTTFQTPTKLYFAMEYAPGGELFFHLERKGAFHIH
| || .||.| .|.|||| . .... ||.|.. |   |    |.  ..|.|.|  ..||||| ... |||....||. |||.||||.| .| ..| |   
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

DVRIYVA-ELALAIEYLHDNNIIYRDIKPENILLDSEGHVKITDFGLSKEMEEDTTSTLCGSPNYMAPEIITHT-RYGPAVDWWSLGILMYEMLFGVQPF
. ..|.| .  ||.||||  |||||| ||||||.|..||.|||||| .|....  |.|||| | |.|||||. .  .| .||||.|||| ||||.|. ||
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD-RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPF

VNE--NKSVLLMMIATCRVSFPRNANPDA---QSLILGLLQKNPSERF-----GFEQIKSHPFF
 ..  ..  .   |. ... |||. ..||    .||  |||.....|.     | ..|| |..|
YDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 96997.m00086.AA PKC 106-356 43 9.20000000001e-108 350.4 In-house 1-262 (262) Show / Hide 
Range on Protein: 106-356
Range on HMM: 1-262/262
Sequence Identity: 43% (115 aa)

FRIISVLGRGYYGKVMLCEENTTKELYAIKTIHKKMLVNSDKVQNALTERNVLVRVH-HPFIVSLKTTFQTPTKLYFAMEYAPGGELFFHLERKGAFHIH
|. . |||.| .||||| |   |.|.|||| . | . .  | |  ..||. ||     ||| ..|  .|||. .|.|.|||  || | ||  . . |   
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

DVRIYVAELALAIEYLHDNNIIYRDIKPENILLDSEGHVKITDFGLSKE--MEEDTTSTLCGSPNYMAPEIITHTRYGPAVDWWSLGILMYEMLFGVQPF
  | | || ..|  .||...||||| | .|.|||.|||.||.|||..||  ...||||| || |.|.||||.    ||..||||..|.|||||. |  ||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

VNENKSVLLMMIATCRVSFPRNANPDAQSLILGLLQKNPSERFGF--------EQIKSHPFF
  |.   |   | . ....||    .| |.. |...|||..| |         . |..||||
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase 96997.m00086.AA S_TKc 106-356 34 3e-107 363.52 SMART 1-231 (231) Show / Hide 
Range on Protein: 106-356
Range on HMM: 1-231/231
Sequence Identity: 34% (93 aa)

FRIISVLGRGYYGKVMLCEENTTKELYAIKTIHKKMLVNSDKVQNALTERNVLVRVHHPFIVSLKTTFQTPTKLYFAMEYAPG--GELFFHLERKGA---
..|. ..|.| .|||..| .. |....||| |.          .... |...| . |||.|| |. .||. ..||. |||..|  |.|| .....|    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FHIHDVRIYVAELALAIEYLHDNNIIYRDIKPENILLDSEGHVKITDFGLSKEMEEDTTSTLCGSPNYMAPEIITHTRYGP-AVDWWSLGILMYEML
   |.  ..| |......|.||.|...||.||.||||||||.  |.||.||||....     .|.||.|.|||||..    ||. ..||||.|...||||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

FGVQPFVNENKSVLLMMIATCRVSFPRNANPDAQSLILGLLQKNPSERFGFEQIKS-------HPFF
 |  ||   .  ... .|            |.| ..| ..|||.|..| .  ..         ||.|
CGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 96997.m00086.AA RSK-Unclassified 106-356 38 1.8e-99 313.11 In-house 1-283 (283) Show / Hide 
Range on Protein: 106-356
Range on HMM: 1-283/283
Sequence Identity: 38% (110 aa)

FRIISVLGRGYYGKVMLCEENTTKELYAIKTIHKKMLVNSDKVQNALTERNVLVRVHHPFIVSLKTTFQTPTKLYFAMEYAPGGELFFHLE--RKGAFHI
|  .  .|.|  ||| | ..  |. .||.|  ||. ..   |.. ..||.|..    ||||| |   |||  .||  ||| .||..| ||   ..  |  
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

HDVRIYVAELALAIEYLHDNNIIYRDIKPENILLDSEGHVKITDFGLSKEM-----------------------EEDTTSTLCGSPNYMAPEIITHTRYG
 |||.|..|  .| ||||   .|||| ||.||.|. ||||. |||.||..                        .   |   ||.  |.|||.|     .
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGHT

PAVDWWSLGILMYEMLFGVQPFVNENKSVLLMMIATCRVSFP--RNANPDAQSLILGLLQKNPSERFG-----FEQIKSHPFF
 ||||| |||.|||||||. |.  .||  .   | .  |.||       ....||  |||.||. | |      . || ||||
KAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF
Kinase 96997.m00086.AA Pkinase 106-356 31 3.7e-97 333.87 Pfam 1-293 (293) Show / Hide 
Range on Protein: 106-356
Range on HMM: 1-293/293
Sequence Identity: 31% (93 aa)

FRIISVLGRGYYGKVMLCEENTTKELYAIKTIHKKMLVNSDKVQNAL-TERNVLVRVHHPFIVSLKTTFQTPTKLYFAMEYAPGG----ELFFHLE--RK
..|....|.| .|.| .| .  | ...|.|.| |.    . ...... .|  .. |..||.|| |. .|......|. |||..||    .|| ...  |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GAF--HIHDVRIYVAELALAIEYLHDNNIIYRDIKPENILLDSEGHV----KITDFGLSK---EMEEDTTSTLCGSPNYMAPEIIT-HTRYGPAVDWWSL
|.|    .... |. ... ..||.|...||.||.||||||.|..||.    ||.||||.|   .     ..|.||.|.|||||.|  .. |||.||.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GILMYEMLFGVQPFVNE------NKSVLLMMIATCRVSFPR---------------------NANPDAQSLILGLLQKNPSERFGFEQIKSHPFF
|...||||.|  || ..      .. ... .|  ....|..                     |........| ..|.|.|..| ..|||. ||.|
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 96997.m00086.AA p70 106-356 37 3.9e-93 315.73 In-house 1-299 (299) Show / Hide 
Range on Protein: 106-356
Range on HMM: 1-299/299
Sequence Identity: 37% (113 aa)

FRIISVLGRGYYGKVMLCEENT---TKELYAIKTIHKKMLVNSDKVQNALT--------------------------ERNVLVRVHHPFIVSLKTTFQTP
|  . |||.| ||||..    |   |  .|| | . | . | . |                                |||.|  | ||||. |   ||| 
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTN

TKLYFAMEYAPGGELFFHLERKGAFHIHDVRIYVAELALAIEYLHDNNIIYRDIKPENILLDSEGHVKITDFGLSKEMEEDTTS------------TLCG
 |||   || .||||| ||||.| .    .. | .|  .|.|.||   ||||| ||||..|.. |||. |||||.||  .| .             |.||
GKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCG

SPNYMAPEIITHTRYGPAVDWWSLGILMYEMLFGVQPFVNENKSVLLMMIATCR--VSFPRNANPDAQSLILGLLQKNPSERFG-----FEQIKSHPFF
 . ||||||.. . .. ||||||||.||| || |. ||  ||. .    |  ..  .. |    ...  ||  || ..|..| |      ..|..||||
TIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF
Kinase 96997.m00086.AA RSK 106-356 37 7.2e-92 311.51 In-house 1-271 (271) Show / Hide 
Range on Protein: 106-356
Range on HMM: 1-271/271
Sequence Identity: 37% (102 aa)

FRIISVLGRGYYGKVMLCEEN---TTKELYAIKTIHKKMLVNSDKVQNALTERNVLVRVHHPFIVSLKTTFQTPTKLYFAMEYAPGGELFFHLERKGAFH
. .....|.| ..|| .|       |. .||.| | |. ....|. . . .||..|  .|||||| |.  ||. .|.|  |. . ||.|| .| ... | 
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMFS

IHDVRIYVAELALAIEYLHDNNIIYRDIKPENILLDSE----GHVKITDFGLSKEM--EEDTTSTLCGSPNYMAPEIITHTRYGPAVDWWSLGILMYEML
  .|..| ||.||| ||||   |..|| ||||||.|.|    ||.||.|||..|..  |.  . | |.. ||||||..    .. |.||||.|.||||||
EREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEML

FGVQPFVNENKSVLLMMIATCRVSF-------PRNANPDAQSLILGLLQKNPSERFGF-----EQIKSHPFF
 |  ||.| ..  .  .|.   .         . .  . |..|. ..|  .|  | |      ||||.||.|
TGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase 96997.m00086.AA Pkinase_Tyr 106-296 27 6.1e-19 64.78 Pfam 1-208 (270) Show / Hide 
Range on Protein: 106-296
Range on HMM: 1-208/270
Sequence Identity: 27% (57 aa)

FRIISVLGRGYYGKVMLCEEN----TTKELYAIKTIHKKMLVNSDK--VQNALTERNVLVRV-HHPFIVSLKTTFQ--TPT-KLYFAMEYAPGGELFFHL
 ... .||.| .|.|.... .     ||   |.|..  |    ..    .  . | ...    ||| ||.|           ..|  |||.|.| |  .|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML--KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

ER----KGAFHIHDVRIYVAELALAIEYLHDNNIIYRDIKPENILLDSEGHVKITDFGLSKEM-EEDTT-STLC---GSPNYMAPEIITHTRYGPAVDWW
 .    |... ..|   . .. | . |||...|.| ||.   |.|......|||.||||.. . ..|.   .          |||| | . ..  . | |
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVW

SLGILMYEML
| |.||.|..
SFGVLMWEIF
Kinase 96997.m00086.AA TyrKc 106-356 23 2.1e-18 68.37 SMART 1-280 (280) Show / Hide 
Range on Protein: 106-356
Range on HMM: 1-280/280
Sequence Identity: 23% (69 aa)

FRIISVLGRGYYGKVMLCEENTTKELYAIKTIHKKMLVNSDKVQNALTERNVLVRV--HHPFIVSLKTTFQTP-------TKLYFAMEYAPGGELFFHLE
 . . .||.| .|.|.... .   .  |.|....        ..  . | ... ..  ||| || |     ..         |.  |||.|.| |  .| 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

RKGA-FHIHDVRIYVAELALAIEYLHDNNIIYRDIKPENILLDSEGHVKITDFGLSKEMEED------TTSTLC----GSP-----NYMAPEIITHTRYG
...  .   |   .    |   ||||..|.| ||.   |.|......|||.|||||.. ..|      .         |.        |||| | . .. 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

PAVDWWSLGILMYEML-FGVQPFVN------ENKSVLLMMIATCRVSFPRN--------ANPDAQSLILGLLQKNPSERFGFEQIKSHPFF
.. | || |..|.|.. .| ||  .      .|. |.    .  |   | |        . ..  ....   . .|..|  |..|  | .|
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 96997.m00086.AA S_TK_X 357-416 27 1e-05 25.96 SMART 1-79 (79) Show / Hide 
Range on Protein: 357-416
Range on HMM: 1-79/79
Sequence Identity: 27% (22 aa)

QGRDFDDYLQ--KKVKPIFVPISL----RRTDPVNFSTEFTQETPTDSVGSPLSCNK-------------EFEGFSFNG
 | |.|. ..  |...| |.|         ||  || .||| |||.... .| ..|              .|.||... 
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF